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2017 | OriginalPaper | Chapter

9. Directional Transportation of Assembled Molecular Linear Motors

Authors : Ning Zhang, Xiang-Dong Li

Published in: Supramolecular Chemistry of Biomimetic Systems

Publisher: Springer Singapore

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Abstract

The transport and localization of organelles within a eukaryotic cell are dependent on a complex network of protein filaments called the cytoskeleton and the associated proteins, including actin filaments and myosins. Myosin is a molecular motor which has ATPase activity and is able to convert the energy from ATP into mechanical movement along actin filaments. To transport cargo efficiently and to prevent the futile hydrolysis of ATP, the motor activity of myosin must be tightly regulated. In the past two decades, considerable progress has been achieved in understanding new myosins and regulatory mechanism of myosin motors. This chapter will present a general view of myosin family and focus on the structure, function, and regulation of three myosins, i.e., smooth muscle myosin-2, myosin-5, and myosin-19.

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Metadata
Title
Directional Transportation of Assembled Molecular Linear Motors
Authors
Ning Zhang
Xiang-Dong Li
Copyright Year
2017
Publisher
Springer Singapore
DOI
https://doi.org/10.1007/978-981-10-6059-5_9

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