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Journal of Materials Engineering and Performance
Published in: Journal of Materials Engineering and Performance 1/2019

10-12-2018

Effects of Heat Treatment on Microstructure, Mechanical Properties, Corrosion Resistance and Cytotoxicity of ZM21 Magnesium Alloy as Biomaterials

Authors: Dayue Jiang, Yilong Dai, Yu Zhang, Yang Yan, Jiaji Ma, Ding Li, Kun Yu

Published in: Journal of Materials Engineering and Performance | Issue 1/2019

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Abstract

The effects of heat treatment on microstructure, mechanical properties, corrosion resistance and cytotoxicity of extruded Mg-2Zn-1Mn (wt.%) alloy were investigated for biomedical application in this study. The extruded alloy was T4 treated at 510 °C for 4 h and T5 treated at 200 °C for 16 h separately. The extruded Mg-Zn-Mn alloy mainly consists of MgxMny phases. After T4 treatment, the amount of MgxMny phases decreases and average grain size rises from 8 to 24 μm. After T5 treatment, Mg7Zn3 phase newly precipitates along the grain boundaries and the size of grain remains similar. Compared with the T4-treated samples, the extruded and T5-treated samples exhibit higher mechanical properties. The T5-treated samples have an ultimate tensile stress of 273 MPa and an elongation of 19.7%. On the other hand, T4-treated samples present higher corrosion resistance in electrochemical tests. The degradation rates of extruded, T4-treated and T5-treated samples are 0.44 mm/year, 0.48 mm/year and 0.50 mm/year, respectively, in Ringer’s solution at 37 ± 0.2 °C. In addition, T4-treated alloy does not induce toxicity to the L-929 cells in in vitro cytotoxicity test.
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Literature
1.
P. Trumbo, S. Schlicker, A.A. Yates, and M. Poos, Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein and Amino Acids, J. Am. Diet. Assoc., 2002, 102, p 1621–1630CrossRef
2.
F. Witte, J. Fischer, J. Nellesen, H.A. Crostack, V. Kaese, A. Pisch, F. Beckmann, and H. Windhagen, In Vitro and In Vivo Corrosion Measurements of Magnesium Alloys, Biomaterials, 2006, 27, p 1013–1018CrossRef
3.
P. Zartner, R. Cesnjevar, H. Singer, and M. Weyand, First Successful Implantation of a Biodegradable Metal Stent into the Left Pulmonary Artery of a Preterm Baby, Catheter. Cardiovasc. Interv., 2005, 66, p 590–594CrossRef
4.
D. Tie, R. Guan, H. Liu, A. Cipriano, Y. Liu, Q. Wang, Y. Huang, and N. Hort, An In Vivo Study on the Metabolism and Osteogenic Activity of Bioabsorbable Mg-1Sr Alloy, Acta Biomater., 2016, 29, p 455–467CrossRef
5.
S. Zhang, X. Zhang, C. Zhao, J. Li, Y. Song, C. Xie, H. Tao, Y. Zhang, Y. He, Y. Jiang, and Y. Bian, Research on an Mg-Zn Alloy as a Degradable Biomaterial, Acta Biomater., 2010, 6, p 626–640CrossRef
6.
Z. Li, X. Gu, S. Lou, and Y. Zheng, The Development of Binary Mg-Ca Alloys for Use as Biodegradable Materials Within Bone, Biomaterials, 2008, 29, p 1329–1344CrossRef
7.
K. Yu, L. Chen, J. Zhao, S. Li, Y. Dai, Q. Huang, and Z. Yu, In Vitro Corrosion Behavior and In Vivo Biodegradation of Biomedical β-Ca3(PO4)2/Mg–Zn Composites, Acta Biomater., 2012, 8, p 2845–2855CrossRef
8.
M.B. Kannan and R.K. Raman, In Vitro Degradation and Mechanical Integrity of Calcium-Containing Magnesium Alloys in Modified-Simulated Body Fluid, Biomaterials, 2008, 29, p 2306CrossRef
9.
V. Kaesel, P.T. Tai, F.W. Bach, H. Haferkamp, F. Witte, H. Windhagen, Approach to control the corrosion of magnesium by alloying, in: Magnesium: Proceedings of the 6th International Conference Magnesium Alloys and Their Applications, 2005, p. 534–539
10.
A. McGoron and D. Persaud-Sharma, Biodegradable Magnesium Alloys: A Review of Material Development and Applications, J. Biomater. Tissue Eng., 2011, 12, p 25–39
11.
M. Erinc, W.H. Sillekens, R. Mannens, and R.J. Werkhoven, Applicability of existing magnesium alloys as biomedical implant materials, Magnesium Technology. San Francisco, E.A. Nyberg, S.R. Agnew, N.R. Neelameggham, and M.Q. Pekguleryuz, Ed., Minerals, Metals and Materials Society, Warrendale, 2009, p 209–214
12.
M. Bamberger and G. Dehm, Trends in the Development of New Mg Alloys, Ann. Rev. Mater. Res., 2008, 38, p 505–533CrossRef
13.
T.D. Luckey and B. Venugopal, Metal Toxicity in Mammals. Volume 1. Physiologic and Chemical Basis for Metal Toxicity, Biochem. Soc. Trans., 1977, 6, p 819–820
14.
G. Song, Control of Biodegradation of Biocompatable Magnesium Alloys, Corros. Sci., 2007, 49, p 1696–1701CrossRef
15.
S. Farè, Q. Ge, M. Vedani, G. Vimercati, D. Gastaldi, F. Migliavacca, L. Petrini, and S. Trasatti, Evaluation of Material Properties and Design Requirements for Biodegradable Magnesium Stents, Matéria, 2010, 15(2), p 96–103
16.
E. Zhang, D. Yin, L. Xu, L. Yang, and K. Yang, Microstructure, Mechanical and Corrosion Properties and Biocompatibility of Mg–Zn–Mn Alloys for Biomedical Application, Mater. Sci. Eng. C Mater. Biol. Appl., 2009, 29, p 987–993CrossRef
17.
Y. Chen, Z. Xu, C. Smith, and J. Sankar, Recent Advances on the Development of Magnesium Alloys for Biodegradable Implants, Acta Biomater., 2014, 10, p 4561CrossRef
18.
Y. Song, E.H. Han, D. Shan, D.Y. Chang, and B.S. You, The Role of Second Phases in the Corrosion Behavior of Mg–5Zn Alloy, Corros. Sci., 2012, 60, p 238–245CrossRef
19.
X.-B. Liu, D.-Y. Shan, Y.-W. Song, and E.-H. Han, Effects of Heat Treatment on Corrosion Behaviors of Mg-3Zn Magnesium Alloy, Trans. Nonferrous Metal Soc., 2010, 20, p 1345–1350CrossRef
20.
X. Liu, D. Shan, Y. Song, R. Chen, and E. Han, Influences of the Quantity of Mg 2 Sn Phase on the Corrosion Behavior of Mg–7Sn Magnesium Alloy, Electrochim. Acta, 2011, 56, p 2582–2590CrossRef
21.
Y. Wang, D. Tie, R. Guan, N. Wang, Y. Shang, T. Cui, and J. Li, Microstructures, Mechanical Properties, and Degradation Behaviors of Heat-Treated Mg-Sr Alloys as Potential Biodegradable Implant Materials, J Mech. Behav. Biomed., 2018, 77, p 47–57CrossRef
22.
X. Li, J.-H. Jiang, Y.-H. Zhao, A.-B. Ma, D.-J. Wen, and Y.-T. Zhu, Effect of Equal-Channel Angular Pressing and Aging on Corrosion Behavior of ZK60Mg Alloy, Trans. Nonferrous Metal Soc., 2015, 25, p 3909–3920CrossRef
23.
Y. Yan, H. Cao, Y. Kang, K. Yu, T. Xiao, J. Luo, Y. Deng, H. Fang, H. Xiong, and Y. Dai, Effects of Zn Concentration and Heat Treatment on the Microstructure, Mechanical Properties and Corrosion Behavior of As-Extruded Mg-Zn Alloys Produced by Powder Metallurgy, J. Alloy. Compd., 2017, 693, p 1277–1289CrossRef
24.
International A. Standard Test Methods for Determining Average Grain Size, 2013
25.
J.A. Helsen and H. Jürgen Breme, Metals as Biomaterials, Wiley, New York, 1998, p 522ISBN 0-471-96935-4
26.
Z. Shi and A. Atrens, An Innovative Specimen Configuration for the Study of Mg Corrosion, Corros. Sci., 2011, 53, p 226–246CrossRef
27.
B.S. Institution, EN ISO 10993-5. Biological evaluation of medical devices. Part 5. Tests for in vitro cytotoxicity, ANSI/AAMI, Arlington, 1999
28.
Y. Zhou, Y. Li, D. Luo, Y. Ding, and P. Hodgson, Microstructures, Mechanical and Corrosion Properties and Biocompatibility of as Extruded Mg–Mn–Zn–Nd Alloys for Biomedical Applications, Mater. Sci. Eng. C Mater. Biol. Appl., 2015, 49, p 93–100CrossRef
29.
X. Wang, P. Zhang, L.H. Dong, X.L. Ma, J.T. Li, and Y.F. Zheng, Microstructure and Characteristics of Interpenetrating β-TCP/Mg–Zn–Mn Composite Fabricated by Suction Casting, Mater. Des., 2014, 54, p 995–1001CrossRef
30.
D. Lin, F. Hung, T. Lui, and M. Yeh, Heat Treatment Mechanism and Biodegradable Characteristics of ZAX1330Mg Alloy, Mater. Sci. Eng. C Mater. Biol. Appl., 2015, 51, p 300–308CrossRef
31.
Y. Song, E.-H. Han, D. Shan, C.D. Yim, and B.S. You, The Effect of Zn Concentration on the Corrosion Behavior of Mg–xZn alloys, Corros. Sci., 2012, 65, p 322–330CrossRef
32.
C.N. Cao and J.Q. Zhang, An Introduction of Electrochemical Impedance Spectroscopy Science, Science Press, Beijing, 2002, p 86–106
33.
M. Jamesh, S. Kumar, and T.S.N.S. Narayanan, Corrosion Behavior of Commercially Pure Mg and ZM21Mg Alloy in Ringer’s Solution—Long Term Evaluation by EIS, Corros. Sci., 2011, 53, p 645–654CrossRef
34.
G. Song, A. Atrens, D. Stjohn, J. Nairn, and Y. Li, The Electrochemical Corrosion of Pure Magnesium in 1N NaCl, Corros. Sci., 1997, 39, p 855–875CrossRef
35.
Okamoto H, Phase Diagrams for Binary Alloys, in Workshops on Abstract State Machines, 2000.
36.
E.O. Hall, Yield Point Phenomena in Metals and Alloys, Macmillan, London, 1970CrossRef
37.
A.J. Ardell, Precipitation Hardening, Metall. Trans. A, 1985, 16, p 2131–2165CrossRef
38.
D. Zhang, X. Hao, D. Fang, and Y. Chai, Effects of Heat Treatment on Microstructure and Mechanical Properties of as-Extruded Mg-9Sn-1.5Y-0.4Zr Magnesium Alloy, Rare Metal Mater. Eng., 2016, 45, p 2208–2213CrossRef
39.
S.Z. Zhu, T.J. Luo, T.A. Zhang, Y.T. Liu, and Y.S. Yang, Effects of Extrusion and Heat Treatments on Microstructure and Mechanical Properties of Mg–8Zn–1Al–0.5Cu–0.5Mn Alloy, Trans. Nonferrous Metal Soc., 2017, 27, p 73–81CrossRef
40.
H. Zhang, J. Fan, L. Zhang, G. Wu, W. Liu, W. Cui, and S. Feng, Effect of Heat Treatment on Microstructure, Mechanical Properties and Fracture Behaviors of Sand-Cast Mg-4Y-3Nd-1Gd-0.2Zn-0.5Zr Alloy, Mater. Sci. Eng. A Struct. Mater., 2016, 677, p 411–420CrossRef
41.
M.P. Staiger, A.M. Pietak, J. Huadmai, and G. Dias, Magnesium and its Alloys as Orthopedic Biomaterials: A Review, Biomaterials, 2006, 27, p 1728–1734CrossRef
42.
A. Atrens, G.L. Song, M. Liu, Z. Shi, F. Cao, and M.S. Dargusch, Review of Recent Developments in the Field of Magnesium Corrosion, Adv. Eng. Mater., 2015, 17, p 400–453CrossRef
43.
G.L. Song, 1–Corrosion electrochemistry of magnesium (Mg) and its alloys, Corrosion of Magnesium Alloys, G.L. Song, Ed., Woodhead, Cambridge, 2011, p 3–65 CrossRef
44.
G. Song, A. Atrens, and M. Dargusch, Influence of Microstructure on the Corrosion of Diecast AZ91D, Corros. Sci., 1998, 41, p 249–273CrossRef
45.
M.M. Avedesian, H. Baker, Magnesium and magnesium alloys-ASM specialty handbook, in Workshops on Abstract State Machines, 1999
46.
A. Atrens, M. Liu, N.I.Z. Abidin, and G.L. Song, 3–Corrosion of magnesium (Mg) alloys and metallurgical influence, Corrosion of Magnesium Alloys, G.L. Song, Ed., Woodhead, Cambridge, 2011, p 117–165 CrossRef
47.
A. Atrens, G.L. Song, F. Cao, Z. Shi, and P.K. Bowen, Advances in Mg Corrosion and Research Suggestions, J. Magn. Alloys, 2013, 1, p 177–200CrossRef
48.
Z. Shi, F. Cao, G.L. Song, and A. Atrens, Low Apparent Valence of Mg During Corrosion, Corros. Sci., 2014, 88, p 434–443CrossRef
49.
A. Pardo, M.C. Merino, A.E. Coy, R. Arrabal, F. Viejo, and E. Matykina, Corrosion Behaviour of Magnesium/Aluminium Alloys in 3.5 wt% NaCl, Corros. Sci., 2008, 50, p 823–834CrossRef
50.
X. Gu, W. Zhou, Y. Zheng, L. Dong, Y. Xi, and D. Chai, Microstructure, Mechanical Property, Bio-Corrosion and Cytotoxicity Evaluations of Mg/HA Composites, Mater. Sci. Eng. C Mater. Biol. Appl., 2010, 30, p 827–832CrossRef
51.
Y. Dai, Y. Lu, D. Li, K. Yu, D. Jiang, Y. Yan, L. Chen, and T. Xiao, Effects of Polycaprolactone Coating on the Biodegradable Behavior and Cytotoxicity of Mg-6%Zn-10%Ca3(PO4)2 Composite in Simulated Body Fluid, Mater. Lett., 2017, 198, p 118–120CrossRef
Metadata
Title
Effects of Heat Treatment on Microstructure, Mechanical Properties, Corrosion Resistance and Cytotoxicity of ZM21 Magnesium Alloy as Biomaterials
Authors
Dayue Jiang
Yilong Dai
Yu Zhang
Yang Yan
Jiaji Ma
Ding Li
Kun Yu
Publication date
10-12-2018
Publisher
Springer US
Published in
Journal of Materials Engineering and Performance / Issue 1/2019
Print ISSN: 1059-9495
Electronic ISSN: 1544-1024
DOI
https://doi.org/10.1007/s11665-018-3781-0

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