Abstract
Process capability modeling became a tool for the systematization and codification of knowledge for process oriented activities in various areas. Enterprise SPICE defines a domain independent integrated model for enterprise-wide assessment and continuous process improvement. This paper presents the use of a SPICE conformant application dependent process modeling to support a smart specialization based regional innovation strategy process. Smart specialization is the main approach for the development and implementation of innovation strategies to improve of European regions within the programming period 2014–2020 driven by EU structural funds. The work presented in this paper provides the details of the regional innovation strategy process capability assessment model that is designed as an extension of the Enterprise SPICE Model.