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Journal of Nanoparticle Research

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01-01-2015 | Research Paper

Evaluation of magnetic- and carbon-based nano-adsorbents application in pre-purification of paclitaxel from needles of Taxus baccata

Authors: M. R. Naghavi, E. Motamedi, J. Nasiri, H. Alizadeh, M. R. Fattahi Moghadam, A. Mashouf

Published in: Journal of Nanoparticle Research | Issue 1/2015

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Abstract

In this investigation, the proficiency of a number of magnetic carbon-based nano-adsorbents is evaluated in pre-purification process of the crude paclitaxel extract obtained from fresh needles of yew tree (Taxus baccata L.). The effectiveness and removal ability of color and impurities from crude extracts, for three novel candidate nano-adsorbents (i.e., Fe₃O₄ nanoparticles (Fe₃O₄Nps), graphite oxide (GO), and their hybrids Fe₃O₄Nps/GO) are compared with commercial graphite in three different solvents. In general, both HPLC and UV–Vis spectroscopy results demonstrate that in less polar solvent (i.e., dichloromethane), the adsorption is greatly affected by the electrostatic attractions, while in more polar solvents (i.e., acetone and ethanol) π–π electron interactions taking place between adsorbent and adsorbate are the most dominant factors in sorption. Considering decolorization efficiency, purity of taxol, recovery and reusability of adsorbents, Fe₃O₄Nps/GO (50 g/L) in dichloromethane is selected as the best medium for pre-purification of paclitaxel. Additionally, in kinetic studies the sorption equilibrium can be reached within 120 min, and the experimental data are well fitted by the pseudo-second-order model. The Langmuir sorption isotherm model correlates well with the sorption equilibrium data for the crude extract concentration (500–2,000 mg/L). Our findings display promising applications of Fe₃O₄Nps/GO, as a cost-effective nano-adsorbent, to provide a suitable vehicle toward improvement of paclitaxel pre-purification.

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Allen MJ, Tung VC, Kaner RB (2009) Honeycomb carbon: a review of graphene. Chem Rev 110:132–145CrossRef

Ambashta RD, Sillanpää M (2010) Water purification using magnetic assistance: a review. J Hazard Mater 180:38–49CrossRef

Badruddoza A, Tay A, Tan P, Hidajat K, Uddin M (2011) Carboxymethyl-β-cyclodextrin conjugated magnetic nanoparticles as nano-adsorbents for removal of copper ions: synthesis and adsorption studies. J Hazard Mater 185:1177–1186CrossRef

Bai Y, Ehlert M, Foo SSK (2000) Method for high yield and large scale extraction of paclitaxel from paclitaxel-containing material. Google Patents

Bourlinos AB, Gournis D, Petridis D, Szabó T, Szeri A, Dékány I (2003) Graphite oxide: chemical reduction to graphite and surface modification with primary aliphatic amines and amino acids. Langmuir 19:6050–6055CrossRef

Cao A, Liu Z, Chu S, Wu M, Ye Z, Cai Z, Chang Y, Wang S, Gong Q, Liu Y (2010) A facile one-step method to produce graphene–CdS quantum dot nanocomposites as promising optoelectronic materials. Adv Mater 22:103–106CrossRef

Chen J, Zou J, Zeng J, Song X, Ji J, Wang Y, Ha J, Chen X (2010) Preparation and evaluation of graphene-coated solid-phase microextraction fiber. Anal Chim Acta 678:44–49CrossRef

Chiou F-Y, Kan P, Chu I-M, Lee C-J (1997) Separation of taxol and cephalomannine by countercurrent chromatography. J Liq Chromatogr Relat Technol 20:57–61CrossRef

Delgado-Vargas F, Jiménez A, Paredes-López O (2000) Natural pigments: carotenoids, anthocyanins, and betalains—characteristics, biosynthesis, processing, and stability. Crit Rev Food Sci Nutr 40:173–289CrossRef

Dreyer DR, Park S, Bielawski CW, Ruoff RS (2010) The chemistry of graphene oxide. Chem Soc Rev 39:228–240CrossRef

Fan F-L, Qin Z, Bai J, Rong W-D, Fan F-Y, Tian W, Wu X-L, Wang Y, Zhao L (2012) Rapid removal of uranium from aqueous solutions using magnetic Fe₃O₄–SiO₂ composite particles. J Environ Radioact 106:40–46CrossRef

Ferrari A, Robertson J (2000) Interpretation of Raman spectra of disordered and amorphous carbon. Phys Rev B 61:14095CrossRef

Fornasiero P, Kašpar J, Graziani M (1999) On the rate determining step in the reduction of CeO₂–ZrO₂ mixed oxides. Appl Catal B Environ 22:L11–L14CrossRef

Freundlich H (1906) Über die adsorption in lösungen. Zeitschrift für Physikalische Chemie 57:385–470

Frey NA, Peng S, Cheng K, Sun S (2009) Magnetic nanoparticles: synthesis, functionalization, and applications in bioimaging and magnetic energy storage. Chem Soc Rev 38:2532–2542CrossRef

Gao Y, Li Y, Zhang L, Huang H, Hu J, Shah SM, Su X (2012) Adsorption and removal of tetracycline antibiotics from aqueous solution by graphene oxide. J Colloid Interf Sci 368:540–546CrossRef

Geim AK (2009) Graphene: status and prospects. Science 324:1530–1534CrossRef

Geim AK, Novoselov KS (2007) The rise of graphene. Nat Mater 6:183–191CrossRef

Geng J, Jung H-T (2010) Porphyrin functionalized graphene sheets in aqueous suspensions: from the preparation of graphene sheets to highly conductive graphene films. J Phys Chem C 114:8227–8234CrossRef

Gómez-Navarro C, Weitz RT, Bittner AM, Scolari M, Mews A, Burghard M, Kern K (2007) Electronic transport properties of individual chemically reduced graphene oxide sheets. Nano Lett 7:3499–3503CrossRef

Goncalves G, Marques PA, Granadeiro CM, Nogueira HI, Singh M, Gracio J (2009) Surface modification of graphene nanosheets with gold nanoparticles: the role of oxygen moieties at graphene surface on gold nucleation and growth. Chem Mater 21:4796–4802CrossRef

Guibal E, Van Vooren M, Dempsey BA, Roussy J (2006) A review of the use of chitosan for the removal of particulate and dissolved contaminants. Sep Sci Technol 41:2487–2514CrossRef

Hao Y-M, Man C, Hu Z-B (2010) Effective removal of Cu (II) ions from aqueous solution by amino-functionalized magnetic nanoparticles. J Hazard Mater 184:392–399CrossRef

Hartmut K (1983) Determinations of total carotenoids and chlorophylls b of leaf extracts in different solvents. In: Peach K, Tracey MV (eds) Analysis, vol 4., pp 142–196

He H, Klinowski J, Forster M, Lerf A (1998) A new structural model for graphite oxide. Chem Phys Lett 287:53–56CrossRef

Ho Y-S, McKay G (1999) Pseudo-second order model for sorption processes. Process Biochem 34:451–465CrossRef

Huang X, Zhang Y, Yuan D (2013) Preparation of sorbent based on porous monolith incorporated with graphene oxide nanosheets for stir cake sorptive extraction of strongly polar aromatic amines. Anal Methods 6:1510–1516CrossRef

Jang HR, Oh H-J, Kim J-H, Jung KY (2013) Synthesis of mesoporous spherical silica via spray pyrolysis: Pore size control and evaluation of performance in paclitaxel pre-purification. Microporous Mesoporous Mater 165:219–227CrossRef

Kassaee MZ, Motamedi E, Majdi M (2011) Magnetic Fe₃O₄-graphene oxide/polystyrene: fabrication and characterization of a promising nanocomposite. Chem Eng J 172:540–549

Khajeh M, Laurent S, Dastafkan K (2013) Nanoadsorbents: classification, preparation, and applications (with emphasis on aqueous media). Chem Rev 113:7728–7768CrossRef

Kim J-H, Kang I-S, Choi H-K, Hong S-S, Lee H-S (2000) Fractional precipitation for paclitaxel pre-purification from plant cell cultures of Taxus chinensis. Biotechnol Lett 22:1753–1756CrossRef

Langmuir I (1918) The adsorption of gases on plane surfaces of glass, mica and platinum. J Am Chem Soc 40:1361–1403CrossRef

Lerf A, He H, Forster M, Klinowski J (1998) Structure of graphite oxide revisited. J Phys Chem B 102:4477–4482CrossRef

Liao M-H, Chen D-H (2002) Preparation and characterization of a novel magnetic nano-adsorbent. J Mater Chem 12:3654–3659CrossRef

Liu T, Li Y, Du Q, Sun J, Jiao Y, Yang G, Wang Z, Xia Y, Zhang W, Wang K, Zhu H, Wu D (2012) Adsorption of methylene blue from aqueous solution by graphene. Colloids Surf B Biointerfaces 90:197–203CrossRef

Lu AH, EeL Salabas, Schüth F (2007) Magnetic nanoparticles: synthesis, protection, functionalization, and application. Angew Chem Int Ed 46:1222–1244CrossRef

Ma H-L, Zhang Y, Hu Q-H, Yan D, Yu Z-Z, Zhai M (2012) Chemical reduction and removal of Cr(VI) from acidic aqueous solution by ethylenediamine-reduced graphene oxide. J Mater Chem 22:5914–5916CrossRef

Madadrang CJ, Kim HY, Gao G, Wang N, Zhu J, Feng H, Gorring M, Kasner ML, Hou S (2012) Adsorption behavior of EDTA-graphene oxide for Pb(II) removal. ACS Appl Mater Interfaces 4:1186–1193CrossRef

Miao F, Wijeratne S, Zhang Y, Coskun UC, Bao W, Lau CN (2007) Phase coherent transport in graphene quantum billiards. Science 317:1530–1533

Nakada K, Fujita M, Dresselhaus G, Dresselhaus MS (1996) Edge state in graphene ribbons: nanometer size effect and edge shape dependence. Phys Rev B 54:17954CrossRef

Novoselov KS, Geim AK, Morozov S, Jiang D, Zhang Y, Dubonos S, Grigorieva I, Firsov A (2004) Electric field effect in atomically thin carbon films. Science 306:666–669CrossRef

Oh H-J, Jang HR, Jung KY, Kim J-H (2012) Evaluation of adsorbents for separation and purification of paclitaxel from plant cell cultures. Process Biochem 47:331–334CrossRef

Pasricha R, Gupta S, Srivastava AK (2009) A facile and novel synthesis of Ag–graphene-based nanocomposites. Small 5:2253–2259CrossRef

Pyo S-H, Song B-K, Ju C-H, Han B-H, Choi H-J (2005) Effects of absorbent treatment on the purification of paclitaxel from cell cultures of Taxus chinensis and yew tree. Process Biochem 40:1113–1117CrossRef

Rao KV, Hanuman JB, Alvarez C, Stoy M, Juchum J, Davies RM, Baxley R (1995) A new large-scale process for taxol and related taxanes from Taxus brevifolia. Pharm Res 12:1003–1010CrossRef

Rocchiccioli-Deltcheff C, Franck R, Cabuil V, Massart R (1987) Surfacted ferrofluids: interactions at the surfactant-magnetic iron oxide interface. Leuk Res 5:126–127

Scheer H (1991) Structure and occurence of chlorophylls. In: Scheer H (ed) Chlorophylls. CRC-Press, Boca Raton, pp 3–30

Scheuermann GM, Rumi L, Steurer P, Bannwarth W, Mülhaupt R (2009) Palladium nanoparticles on graphite oxide and its functionalized graphene derivatives as highly active catalysts for the Suzuki-Miyaura coupling reaction. J Am Chem Soc 131:8262–8270CrossRef

Stankovich S, Piner RD, Chen X, Wu N, Nguyen ST, Ruoff RS (2006a) Stable aqueous dispersions of graphitic nanoplatelets via the reduction of exfoliated graphite oxide in the presence of poly (sodium 4-styrenesulfonate). J Mater Chem 16:155–158CrossRef

Stankovich S, Piner RD, Nguyen ST, Ruoff RS (2006b) Synthesis and exfoliation of isocyanate-treated graphene oxide nanoplatelets. Carbon 44:3342–3347CrossRef

Tuinstra F, Koenig JL (2003) Raman spectrum of graphite. J Chem Phys 53:1126–1130CrossRef

van Rozendaal EL, Lelyveld GP, van Beek TA (2000) Screening of the needles of different yew species and cultivars for paclitaxel and related taxoids. Phytochemistry 53:383–389CrossRef

Vanhaelen-Fastre R, Diallo B, Jaziri M, Faes M, Homes J, Vanhaelen M (1992) High-speed countercurrent chromatography separation of taxol and related diterpenoids from Taxus baccata. J Liq Chromatogr Relat Technol 15:697–706CrossRef

Wani MC, Taylor HL, Wall ME, Coggon P, McPhail AT (1971) Plant antitumor agents. VI. Isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia. J Am Chem Soc 93:2325–2327CrossRef

Watchueng J, Kamnaing P, Gao J-M, Kiyota T, Yeboah F, Konishi Y (2011) Efficient purification of paclitaxel from yews using high-performance displacement chromatography technique. J Chromatogr A 1218:2929–2935CrossRef

Wu Q, Feng C, Wang C, Wang Z (2013) A facile one-pot solvothermal method to produce superparamagnetic graphene–Fe₃O₄ nanocomposite and its application in the removal of dye from aqueous solution. Colloids Surf B Biointerfaces 101:210–214CrossRef

Xu C, Wang X, Zhu J (2008) Graphene-metal particle nanocomposites. J Phys Chem C 112:19841–19845CrossRef

Xu Y, Liu Z, Zhang X, Wang Y, Tian J, Huang Y, Ma Y, Zhang X, Chen Y (2009) A graphene hybrid material covalently functionalized with porphyrin: synthesis and optical limiting property. Adv Mater 21:1275–1279CrossRef

Yang S-T, Chang Y, Wang H, Liu G, Chen S, Wang Y, Liu Y, Cao A (2010) Folding/aggregation of graphene oxide and its application in Cu²⁺ removal. J Colloid Interface Sci 351:122–127CrossRef

Yang S-T, Chen S, Chang Y, Cao A, Liu Y, Wang H (2011) Removal of methylene blue from aqueous solution by graphene oxide. J Colloid Interf Sci 359:24–29CrossRef

Zhang C, Sui J, Li J, Tang Y, Cai W (2012) Efficient removal of heavy metal ions by thiol-functionalized superparamagnetic carbon nanotubes. Chem Eng J 210:45–52CrossRef

Zhao G, Li J, Ren X, Chen C, Wang X (2011) Few-layered graphene oxide nanosheets as superior sorbents for heavy metal ion pollution management. Environ Sci Technol 45:10454–10462CrossRef

Title: Evaluation of magnetic- and carbon-based nano-adsorbents application in pre-purification of paclitaxel from needles of Taxus baccata
Authors: M. R. Naghavi
E. Motamedi
J. Nasiri
H. Alizadeh
M. R. Fattahi Moghadam
A. Mashouf
Publication date: 01-01-2015
Publisher: Springer Netherlands
Published in: Journal of Nanoparticle Research / Issue 1/2015
Print ISSN: 1388-0764
Electronic ISSN: 1572-896X
DOI: https://doi.org/10.1007/s11051-014-2830-3

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