Evolving Properties of Biological Materials Captured via Needle-Based Cavity Expansion Method

The article delves into the challenges of quantifying the mechanical properties of biological tissues, which change over time and health states. It introduces the Volume Controlled Cavity Expansion (VCCE) method, demonstrated through experiments on gelatin and liver tissues. VCCE allows for localized, non-destructive measurements, capturing subtle changes in tissue stiffness over time. The study reveals that conventional constitutive models may not adequately capture the complexity of these changes, advocating for empirical models. The findings suggest that VCCE could revolutionize diagnostic methods by providing real-time, sensitive measurements of tissue health.