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2010 | OriginalPaper | Chapter

Feedback Control Systems Using Environmentally and Enzymatically Sensitive Hydrogels

Authors : Irma Y. Sanchez, Nicholas A. Peppas

Published in: Biomedical Applications of Hydrogels Handbook

Publisher: Springer New York

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Abstract

A large number of hydrogels can be classified as smart materials that offer a natural integration of sensing, actuating, and regulating functions applicable to feedback control systems. This multifunctionality added to biocompatibility and enzyme-based selectivity characteristics enables self-regulation or implicit control in hydrogels-based devices to maintain physiological variables at a desired level or range by appropriate drug release. Therefore, hydrogels can enhance the performance of individual actuator and sensing units. Applications of hydrogels in explicit and implicit controller systems are presented based on recent experimental and theoretical research studies. Integration of cascade and feedforward control types of functionalities in hydrogels systems is suggested from their capability to respond to more than one stimulus. Enzymatic glucose sensing and insulin delivery are often used as references for the discussion of hydrogels in the development of sensor, actuator, and control technology due to the relevance of the diabetes disease.

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previous chapter Stimuli-Responsive Hydrogels and Their Application to Functional Materials

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Title: Feedback Control Systems Using Environmentally and Enzymatically Sensitive Hydrogels
Authors: Irma Y. Sanchez
Nicholas A. Peppas
Publisher: Springer New York
Book: Biomedical Applications of Hydrogels Handbook
Print ISBN: 978-1-4419-5918-8

Electronic ISBN: 978-1-4419-5919-5

Copyright Year: 2010
DOI: https://doi.org/10.1007/978-1-4419-5919-5_3

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