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2018 | OriginalPaper | Chapter

2. Functionalization of Tamarind Gum for Drug Delivery

Authors : Amit Kumar Nayak, Dilipkumar Pal

Published in: Functional Biopolymers

Publisher: Springer International Publishing

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Abstract

Tamarind gum is a plant polysaccharide extracted from seed endosperm of the plant, Tamarindus indica Linn. (Family: Fabaceae). It is a neutral, nonionic, and branched polysaccharide having water solubility, hydrophilic, gel-forming, and mucoadhesive properties. In addition, tamarind gum is biodegradable, biocompatible, noncarcinogenic, and nonirritant. Tamarind gum is employed as a potential biopolymer in the fields of pharmaceutical, cosmetic, and food applications. In the recent years, it is widely tested and employed in various drug delivery applications as effective pharmaceutical excipients. Tamarind gum is being exploited in the formulation of oral, colon, ocular, buccal, and nasal drug delivery systems. Though tamarind gum is extensively used in various drug delivery formulations, it has some potential drawbacks such as unpleasant odor, dull color, poor solubility in water, tendency of fast degradability in aqueous environment. To overcome these restrictions, tamarind gum has been functionally derivatized through chemical treatment with a variety of functional groups such as carboxymethyl, acetal, hydroxyl alkyl, thiol, polymer grafting, etc. Recently, various functionally derivatized tamarind gums hold a great promise as potential pharmaceutical excipients in different kinds of improved drug delivery systems mainly because of its improved stability (lower degradability). These functionally derivatized tamarind gums hold enhanced mechanical behavior as well as competence in prolonged period-controlling drug releases. The present chapter contends with a broad review of different kinds of functionalizations of tamarind gum for their use in the development of various improved drug delivery systems. The first part includes sources, compositions, properties and uses of tamarind gum. Then, the latter part contains a comprehensive review of different functionalizations of tamarind gum in drug delivery.

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Ahuja M, Kumar S, Kumar A (2013) Tamarind seed polysaccharide-g-poly(N-vinyl-2-pyrrolidone): microwave-assisted synthesis, characterization and evaluation as mucoadhesive polymer. Int J Polym Mater Polym Biomater 62:544–549CrossRef

Ahuja M, Thakur K, Kumar A (2014) Amylopectin-g-poly(N-vinyl-2-pyrrolidone): synthesis, characterization and in vitro release behavior. Carbohydr Polym 108:127–134CrossRef

Avachat AM, Dash RR, Shrotriya SN (2011) Recent investigations of plant based natural gums, mucilages and resins in novel drug delivery systems. Indian J Pharm Educ Res 45:86–99

Avachat A, Gujar KN, Wagh KV (2013) Development and evaluation of tamarind seed glucan-based mucoadhesive buccal films of rizatriptan benzoate. Carbohydr Polym 91:537–542CrossRef

Bahulkar SS, Maunot NM, Surwase SS (2015) Synthesis, characterization of thiolated karaya gum and evaluation of effect of pH on its mucoadhesive and sustained release properties. Carbohydr Polym 130:183–190CrossRef

Bangle GS, Shinde GV, Umalkar DG, Rajesh KS (2011) Natural mucoadhesive material based buccal tablets of nitrendipine-formulation and in-vitro evaluation. J Pharm Res 4:33–38

Bera H, Boddupalli S, Nandikonda S, Kumar S, Nayak AK (2015) Alginate gel-coated oil-entrapped alginate–tamarind gum–magnesium stearate buoyant beads of risperidone. Int J Biol Macromol 78:102–111CrossRef

Bernkop-Schnürch A, Walker G, Zasti H (2001) Thiolation of polycarbophil enhances its inhibition of intestinal brush border membrane bound aminopeptidase N. J Pharm Sci 90:1907–1914CrossRef

Bernkop-Schnürch A, Kast CE, Guggi D (2003) Permeation enhancing polymers in oral delivery of hydrophilic molecules: thiomer/GSH systems. J Control Release 93:95–103CrossRef

Bhattacharya A, Mishra BN (2004) Grafting: a versatile means to modify polymers-technique, factors and application. Prog Polym Sci 29:767–814CrossRef

Bhattacharya A, Ray P (2009) Basic features and techniques. In: Bhattacharaya A, Rawlins J, Ray P (eds) Polymer grafting and crosslinking. Wiley, Hoboken

Chanda R, Mahapatro SK, Mitra T, Roy A, Bahadur S (2008) Development of oral mucoadhesive tablets of tarbutalline sulphate using some natural materials extracted from Albelmoschus esculeatus and Tamarindus indica. Res J Pharm Res 1:46–51

Chandramouli Y, Firoz S, Vikram A, Padmaja C, Chakravarthi RN (2012) Design and evaluation of controlled release matrix tablets of acyclovir sodium using tamarind seed polysaccharide. J Pharm Biol 2:55–62

Das B, Dutta S, Nayak AK, Nanda U (2014) Zinc alginate-carboxymethyl cashew gum microbeads for prolonged drug release: development and optimization. Int J Biol Macromol 70:505–515CrossRef

Datta R, Bandyopadhyay AK (2006) A new nasal drug delivery system for diazepam using natural mucoadhesive polysaccharide obtained from tamarind seeds. Saudi Pharm J 14:115–119

Deveswaran R, Abraham S, Bharath S, Basavraj BV, Furtado S, Madhavan V (2009) Design and characterization of diclofenac sodium tablets containing tamarind seed polysaccharide as release retardant. Int J PharmTech Res 1:191–195

Ghosh S, Pal S (2013) Modified tamarind kernel polysaccharide: a novel matrix for control release of aspirin. Int J Biol Macromol 58:296–300CrossRef

Gowda DV, Mahammad N, Vishnu Datta M (2014) Design and evaluation of carboxymethyl tamarind kernel polysaccharide controlled release spheroids/pellets and investigating the influence of compression. Int J Pharm Pharmaceut Sci 7:103–109

Goyal P, Kumar V, Sharma P (2007) Carboxymethylation of tamarind kernel powder. Carbohydr Polym 69:251–255CrossRef

Goyal P, Kumar V, Sharma P (2008) Cyanoethylation of tamarind kerner powder. Starch/Strake 60:41–47CrossRef

GRAS Notice (GRN) (2014) No. 503, Determination of the GRAS status of the addition of tamarind seed polysaccharide to conventional foods as a stabilizer and thickener. http://www.fda.gov/Food/IngredientsPackagingLabeling/GRAS/NoticeInventory/default.htm

Guilherme MR, Reis AV, Takahashi SH, Rubira AF, Feitosa JPA, Muniz EC (2005) Synthesis of a novel superabsorbent hydrogel by copolymerization of acrylamide and cashew gum modified with glycidyl methacrylate. Carbohydr Polym 61:464–471CrossRef

Gupta V, Puri R, Gupta S, Jain S, Rao GK (2010) Tamarind kernel gum: an upcoming natural polysaccharide. Syst Rev Pharm 1:50–54CrossRef

Hartemink R, Van Laere KMJ, Mertens AKC, Rombouts FM (1996) Fermentation of xyloglucan by intestinal bacteria. Anaerobe 2:223–230CrossRef

Hasnain MS, Nayak AK, Singh R, Ahmad F (2010) Emerging trends of natural-based polymeric systems for drug delivery in tissue engineering applications. Sci J UBU 1:1–13

Hemmati K, Ghaemy M (2016) Synthesis of new thermo/pH sensitive drug delivery systems based on tragacanth gum polysaccharide. Int J Biol Macromol 87:415–425CrossRef

Jana S, Saha A, Nayak AK, Sen KK, Basu SK (2013) Aceclofenac-loaded chitosan-tamarind seed polysaccharide interpenetrating polymeric network microparticles. Colloids Surf B Biointerfaces 105:303–309CrossRef

Jani GK, Shah DP, Prajapati VD, Jain V (2009) Gums and mucilages: versatile excipients for pharmaceutical formulations. Asian J Pharm Sci 4:309–323

Joseph J, Kanchalochana SN, Rajalakshmi G, Hari V, Durai RD (2012) Tamarind seed polysaccharide: a promising natural excipients for pharmaceuticals. Int J Green Pharm 6:270–278CrossRef

Kaur G, Jain S, Tiwary AK (2010) Chitosan-carboxymethyl tamarind kernel powder interpolymer complexation: investigations for colon drug delivery. Sci Pharm 78:57–78CrossRef

Kaur H, Ahuja M, Kumar S, Dilbaghi N (2012a) Carboxymethyl tamarind kernel polysaccharide nanoparticles for ophthalmic drug delivery. Int J Biol Macromol 50:833–839CrossRef

Kaur H, Yadav S, Ahuja M, Dilbaghi N (2012b) Synthesis, characterization and evaluation of thiolated tamarind seed polysaccharide as a mucoadhesive polymer. Carbohydr Polym 90:1543–1549CrossRef

Khalil MI, Hasehem A, Habiesh A (1990) Carboxymethylation of maize starch. Starch/Starke 42:60–63CrossRef

Khanna M, Nandi RC, Sarin JP (1987) Standardization of tamarind seed polyose for pharmaceutical use. Indian Drugs 24:268–269

Krauand AH, Leitner VM, Bernkop-Schnürch A (2003) Improvement in the in situ gelling properties of deactylated gellan gum by immobilization of thiol groups. J Pharm Sci 92:1234–1241CrossRef

Kulkarni GT, Gowthamarajan K, Dhobe RR, Yohanan F, Suresh B (2005) Development of controlled release spheroids using natural polysaccharide as release modifier. Drug Deliv 12:201–206CrossRef

Lang P, Masci G, Dentini M, Crescenzi V, Cooke D, Gidley MJ, Fanutti C, Reid JSG (1992) Tamarind seed polysaccharide: preparation, characterization and solution properties of carboxylated, sulphated and alkalaminated derivatives. Carbohydr Polym 17:185–198CrossRef

Mahajan HS, Tyagi VK, Patil RR, Dusunge SB (2013) Thilated xyloglucan: synthesis, characterization and evaluation as mucoadhesive in situ gelling agent. Carbohydr Polym 91:618–625CrossRef

Maity S, Sa B (2014a) Ca-carboxymethyl xanthan gum mini-matrices: swelling, erosion and their impact on drug release mechanism. Int J Biol Macromol 68:78–85CrossRef

Maity S, Sa B (2014b) Development and evaluation of Ca²⁺ ion crosslinked carboxymethyl xanthan gum tablet prepared by wet granulation technique. AAPS PharmSciTech 15:920–927CrossRef

Manchanda R, Arora SC, Manchanda R (2014) Tamarind seed polysaccharide and its modification-versatile pharmaceutical excipients—a review. Int J PharmTech Res 6:412–420

Manchanda R, Srivastava B, Arora SC, Manchanda R (2015) Optimization of carboxymethyl tamarind seed polysaccharide based glipizide matrix tablets using 3² full factorial design and response surface methodology. Der Pharm Lett 7:297–309

Martinez A, Iglesias I, Lozano R, Teijon JM, Blanco MD (2011) Synthesis and characterization of thiolated alginate–albumin nanoparticles stabilized by disulfide bonds. Evaluation as drug delivery systems. Carbohydr Polym 83:1311–1321CrossRef

Masoumi A, Ghaemy M (2014) Removal of metal ions from water using nanohydrogel tragacanth gum-g-polyamidoxime: isotherm and kinetic study. Carbohydr Polym 108:206–215CrossRef

Meenakshi, Ahuja M (2015) Metronidazole loaded carboxymethyl tamarind kernel polysaccharide-polyvinyl alcohol cryogels: preparation and characterization. Int J Biol Macromol 72:931–938CrossRef

Meenakshi, Ahuja M, Verma P (2014) MW-assisted synthesis of carboxymethyl tamarind kernel polysaccharide-g-polyacrylonitrile: optimization and characterization. Carbohydr Polym 113:532–538CrossRef

Mehra GR, Manish M, Rashi S, Neeraj G, Mishra DN (2010) Enhancement of miotic potential of pilocarpine by tamarind gum based in situ gelling ocular dosage form. Acta Pharm Sci 52:145–154

Mishra MU, Khandare JN (2011) Evaluation of tamarind seed polysaccharide as a biodegradable carrier for colon specific drug delivery. Int J Pharm Pharmaceut Sci 3:139–142

Mishra A, Pal S (2007) Polyacrylonitrile-grafted okra mucilage: a renewable reservoir to polymeric materials. Carbohydr Polym 68:95–100CrossRef

Mishra A, Yadav A, Pal S, Singh A (2006) Biodegradable graft copolymers of fenugreek mucilage and polyacrylamide: a renewable reservoir to biomaterials. Carbohydr Polym 65:58–63CrossRef

Mishra A, Clark JH, Pal S (2008) Modification of okra mucilage with acrylamide: synthesis, characterization and swelling behaviour. Carbohydr Polym 72:608–615CrossRef

Mittal H, Jindal R, Kaith BS, Maity A, Ray SS (2014) Synthesis and flocculation properties of gum ghatti and poly(acrylamide-co-acrylonitrile) based biodegradable hydrogels. Carbohydr Polym 114:321–329CrossRef

Mittal H, Jindal R, Kaith BS, Maity A, Ray SS (2015) Flocculation and adsorption properties of biodegradable gum-ghatti-grafted poly(acrylamide-co-methacrylic acid) hydrogels. Carbohydr Polym 115:617–628CrossRef

Nandi RC (1975) A process for preparation of polyose from the seeds of Tamarindus indica. Indian Patent 142092

Nandi G, Patra P, Priyadarshini R, Kaity S, Ghosh LK (2015) Synthesis, characterization and evaluation of methacrylamide grafted gellan as sustainedrelease tablet matrix. Int J Biol Macromol 72:965–974CrossRef

Nayak AK (2016) Tamarind seed polysaccharide-based multiple-unit systems for sustained drug release. In: Kalia S, Averous L (eds) Biodegradable and bio-based polymers: environmental and biomedical applications. WILEY-Scrivener, Hoboken, pp 469–492CrossRef

Nayak AK, Pal D (2011) Development of pH-sensitive tamarind seed polysaccharide-alginate composite beads for controlled diclofenac sodium delivery using response surface methodology. Int J Biol Macromol 49:784–793CrossRef

Nayak AK, Pal D (2012) Natural polysaccharides for drug delivery in tissue engineering. Everyman’s Sci XLVI:347–352

Nayak AK, Pal D (2013) Ionotropically-gelled mucoadhesive beads for oral metformin HCl delivery: formulation, optimization and antidiabetic evaluation. J Sci Ind Res 72:15–22

Nayak AK, Pal D (2016) Chitosan-based interpenetrating polymeric network systems for sustained drug release. In: Tiwari A, Patra HK, Choi J-W (eds) Advanced theranostics materials. WILEY-Scrivener, Hoboken, pp 183–208

Nayak AK, Pal D, Pany DR, Mohanty B (2010) Evaluation of Spinacia oleracea L. leaves mucilage as innovative suspending agent. J Adv Pharm Technol Res 1:338–341CrossRef

Nayak AK, Pal D, Pradhan J, Ghorai T (2012) The potential of Trigonella foenum-graecum L. seed mucilage as suspending agent. Indian J Pharm Educ Res 46:312–317

Nayak AK, Pal D, Malakar J (2013) Development, optimization and evaluation of emulsion-gelled floating beads using natural polysaccharide-blend for controlled drug release. Polym Eng Sci 53:338–350CrossRef

Nayak AK, Pal D, Santra K (2014a) Development of calcium pectinate-tamarind seed polysaccharide mucoadhesive beads containing metformin HCl. Carbohydr Polym 101:220–230CrossRef

Nayak AK, Pal D, Santra K (2014b) Tamarind seed polysaccharide-gellan mucoadhesive beads for controlled release of metformin HCl. Carbohydr Polym 103:154–163CrossRef

Nayak AK, Pal D, Santra K (2015) Screening of polysaccharides from tamarind, fenugreek and jackfruit seeds as pharmaceutical excipients. Int J Biol Macromol 79:756–760CrossRef

Olusola A, Toluwalope AG, Olutayo O (2014) Carboxymethylation of Anacardium occidentale L. exudate gum: synthesis and characterization. Sch Acad J Pharm 3:213–216

Pal D, Mitra S (2010) A preliminary study on the in vitro antioxidant activity of the stems of Opuntia vulgaris. J Adv Pharm Technol Res 1:268–272CrossRef

Pal D, Nayak AK (2012) Novel tamarind seed polysaccharide-alginate mucoadhesive microspheres for oral gliclazide delivery. Drug Deliv 19:123–131CrossRef

Pal D, Nayak AK (2015) Alginates, blends and microspheres: controlled drug delivery. In: Mishra M (ed) Encyclopedia of biomedical polymers and polymeric biomaterials. Taylor & Francis Group, New York, pp 89–98CrossRef

Pal S, Gorain MK, Giri A, Bandyopadhyayay A, Panda AB (2011) In-situ silica incorporated carboxymethyl tamarind: development and application of a novel hybride nanocomposite. Int J Biol Macromol 49:1152–1159CrossRef

Pal D, Banerjee S, Ghosh A (2012) Dietary-induced cancer prevention: an expanding research arena of emerging diet related to healthcare system. J Adv Pharm Technol Res 3:16–24CrossRef

Pandey BPK, Kumar R, Taunk K (2001) Graft copolymerization of acrylamide onto xanthan gum. Carbohydr Polym 46:185–189CrossRef

Pandey VS, Verma SK, Yadav M, Behari K (2014) Guar gum-g-N,N′-dimethylacrylamide: synthesis, characterization and applications. Carbohydr Polym 99:284–290CrossRef

Parvathy KS, Susheelamma NS, Tharanathan RN, Goankar AK (2005) A simple non-aqueous method for carboxymethylation of galactomannan. Carbohydr Polym 62:137–141CrossRef

Prajapati VD, Jani GK, Moradiya NG, Randeria NP (2013) Pharmaceutical applications of various natural gums, mucilages and their modified forms. Carbohydr Polym 92:1685–1699CrossRef

Prashanth KVH, Tharanathan RN (2003) Studies on graft copolymerization of chitosan with synthetic monomers. Carbohydr Polym 54:343–353CrossRef

Rana V, Rai P, Tiwari AK, Singh RS, Kenedy JF, Knill CJ (2011) Modified gums: approaches and application in drug delivery. Carbohydr Polym 83:1031–1047

Rani P, Sen G, Mishra S, Jha U (2012) Microwave assisted synthesis of polyacrylamide grafted gum ghatti and its application as flocculant. Carbohydr Polym 89:275–281CrossRef

Rao PS, Srivastava HC (1973) Tamarind. In: Whistler RL (ed) Industrial Gums, 2nd edn. Academic Press, New York, pp 369–411CrossRef

Rao PS, Ghosh TP, Krishna S (1946) Extraction and purification of tamarind seed polysaccharide. J Sci Ind Res 4:705

Samal PK, Dangi JS (2014) Isolation, preliminary characterization and hepatoprotective activity of polysaccharides from Tamarindus indica L. Carbohydr Polym 102:1–7CrossRef

Sand A, Yadav M, Mishra DK, Behari K (2010) Modification of alginate by grafting of N-vinyl-2-pyrrolidone and studies of physicochemical properties in terms of swelling capacity, metal-ion uptake and flocculation. Carbohydr Polym 80:1147–1154CrossRef

Sarkar A, Mandre NR, Panda AB, Pal S (2013) Amylopectin grafted with poly(acrylic acid): development and application of a high performance flocculent. Carbohydr Polym 95:753–759CrossRef

Setia A, Kumar R (2014) Microwave assisted synthesis and optimization of Aegle marmelos-g-poly(acrylamide): release kinetics studies. Int J Biol Macromol 65:462–470CrossRef

Sharma R, Ahuja M (2011) Thiolated pectin—synthesis, characterization and evaluation as a mucoadhesive polymer. Carbohydr Polym 85:658–663CrossRef

Sharma BR, Kumar V, Soni PL (2004) Carbamoylethylation of guar gum. Carbohydr Polym 58:449–451CrossRef

Singh B, Chauhan N, Kumar S (2008) Radiation crosslinked psyllium and polyacrylic acid based hydrogels for use in colon specific drug delivery. Carbohydr Polym 73:446–455CrossRef

Singh B, Varshney L, Francis S, Rajneesh (2016) Designing tragacanth gum based sterile hydrogel by radiation method for use in drug delivery and wound dressing applications. Int J Biol Macromol 88:586–602CrossRef

Singha AS, Shama A, Thakur VK (2008) X-ray diffraction, morphological, and thermal studies on methylmethacrylate graft copolymerized Saccharum ciliare fiber. Int J Polym Anal Charact 13(6):447–462CrossRef

Sonawane S, Bhalekar M, Shimpi S (2014) Preparation and evaluation of microshperes of xyloglucan and its thiolated xylogucan derivative. Int J Biol Macromol 69:499–505CrossRef

Tattiyakul J, Muangnapoh C, Poommarinvarakul S (2010) Isolation and rheological properties of tamarind seed polysaccharide from tamarind karnel powder using protease enzyme and high-intensity ultrasound. J Food Sci 75:253–260CrossRef

Thakur VK, Singha AS (2011) Rapid synthesis, characterization, and physicochemical analysis of biopolymer-based graft copolymers. Int J Polym Anal Charact 16(3):153–164CrossRef

Thakur VK, Thakur MK (2015) Recent advances in green hydrogels from lignin: a review. Int J Biol Macromol 72:834–847CrossRef

Thakur VK, Singha AS, Thakur MK (2012) In-air graft copolymerization of ethyl acrylate onto natural cellulosic polymers. Int J Polym Anal Charact 17(1):48–60CrossRef

Thakur VK, Thakur MK, Gupta RK (2013a) Graft copolymers from cellulose: synthesis, characterization and evaluation. Carbohydr Polym 97:18–25CrossRef

Thakur VK, Thakur MK, Gupta RK (2013b) Rapid synthesis of graft copolymers from natural cellulose fibers. Carbohydr Polym 98:820–828CrossRef

Thakur VK, Singha AS, Thakur MK (2013c) Synthesis of natural cellulose-based graft copolymers using methyl methacrylate as an efficient monomer. Adv Polym Technol 32(S1):E741–E748CrossRef

Thakur VK, Thakur MK, Gupta RK (2013d) Graft copolymers from natural polymers using free radical polymerization. Int J Polym Anal Charact 18(7):495–503CrossRef

Thakur VK, Thakur MK, Gupta RK (2014a) Graft copolymers of natural fibers for green composites. Carbohydr Polym 104:87–93CrossRef

Thakur VK, Thunga M, Madbouly SA, Kessler MR (2014b) PMMA-g-SOY as a sustainable novel dielectric material. RSC Adv 4(35):18240–18249CrossRef

Thakur MK, Thakur VK, Gupta RK, Pappu A (2016) Synthesis and applications of biodegradable soy based graft copolymers: a review. ACS Sustain Chem Eng 4(1):1–17CrossRef

Tiwari A, Singh V (2008) Microwave induced synthesis of gum acacia-graft-polyaniline. Carbohydr Polym 74:427–434CrossRef

Togru H, Arsian N (2003) Production of carboxymethyl cellulose from sugar beet pulp cellulose and rheological behaviour of carboxymethylcellulose. Carbohydr Polym 54:74–84

Vijan V, Kaity S, Biswas S, Isaac J, Ghosh A (2012) Microwave assisted synthesis and characterization of acrylamide grafted gellan, application indrug delivery. Carbohydr Polym 90:496–506CrossRef

Wang A, Wang W (2013) Gum-g-copolymers: synthesis, properties and applications. In: Kalia S, Sabaa MW (eds) Polysaccharide based graft copolymers. Springer, Berlin

Zhang J, Xu S, Zhang S, Du Z (2008) Preparation and characterization of tamarind gum/sodium alginate composite gel beads. Iran Polym J 17:899–906

Title: Functionalization of Tamarind Gum for Drug Delivery
Authors: Amit Kumar Nayak
Dilipkumar Pal
Publisher: Springer International Publishing
Book: Functional Biopolymers
Print ISBN: 978-3-319-66416-3

Electronic ISBN: 978-3-319-66417-0

Copyright Year: 2018
DOI: https://doi.org/10.1007/978-3-319-66417-0_2

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