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Published in:
2011 | OriginalPaper | Chapter
Graph Model of Coalescence with Recombinations
Author : Laxmi Parida
Published in: Problem Solving Handbook in Computational Biology and Bioinformatics
Publisher: Springer US
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One of the primary genetic events shaping an autosomal chromosome is
recombination
. This is a process that occurs during meiosis, in eukaryotes, that results in the offsprings having different combinations of (homologous) genes, or chromosomal segments, of the two parents. The presence of these recombination events in the evolutionary history of each chromosome complicates the genetic landscape of a population, and understanding the manifestations of these genetic exchanges in the chromosome sequences has been a subject of intense curiosity (see [Hud83, Gri99, HSW05] and citations therein).