In the modern world, vascular diseases are associated with a high mortality rate. The knowledge of provenance mechanisms is critical to understanding their progress. Hemodynamics englobes important biomechanical factors intervening in different vascular diseases, especially intracranial aneurysms, where the hemodynamic environment actively influences their genesis, growth, and rupture.
In the present study, we assess the influence of the feeding frequency variation on different hemodynamic parameters inside intra-aneurysmal circulation, using computational fluid dynamics (CFD) combined with patient-specific MRI images.
The patient-specific model of Internal Carotid Artery (ICA) aneurysm was reconstructed from (Three-dimensional Time Of Flight Magnetic Resonance Imaging) 3D TOF MRI images. Navies-Stokes equations are solved inside the geometry using the finite-elements method. We carried out Twenty-seven simulations using different inlet flow rate frequencies to assess the influence of this change on hemodynamics in the aneurysm.
The Variation of the feeding frequency Boundary condition revealed the disturbance of the overall hemodynamic parameters assessed intracranial aneurysm (IA). The increase of the inlet frequency allowed observing the disturbance of the association between flow and pressure inside the aneurysmal sac. This dissociation can be related to the stagnation increase inside the aneurysmal dome in response to feeding frequency. Moreover, the flow profiles have been affected by the disturbance of flow pressure association, which allowed the observation of fluctuating pressure values with multiple high-pressure values on the aneurysmal sac and the peri-aneurismal segment.
The intra-aneurysmal flow is influenced highly by the feeding inlet frequency, which imbalance the pressure-flow stability causing an unfavourable hemodynamic environment inside the aneurysmal sac leading to growth or the rupture of the aneurysm.
