Skip to main content
main-content
Top

Hint

Swipe to navigate through the chapters of this book

2019 | OriginalPaper | Chapter

High-Throughput Analytics in the Function of Personalized Medicine

Authors: Djuro Josić, Tamara Martinović, Urh Černigoj, Jana Vidič, Krešimir Pavelić

Published in: Personalized Medicine in Healthcare Systems

Publisher: Springer International Publishing

share
SHARE

Abstract

Rapid and highly reliable analysis of patient sample is the first premise and simultaneously the first step in the direction of right diagnosis and personalized treatment. However, this fact is frequently neglected. Despite this situation, almost unnoticed activities in this field started 55 years ago with the concept of a biosensor for fast monitoring of blood glucose and diabetes control, and blood glucose determination is still the driving force for optimization of these kinds of high-throughput analytical devices. The development of devices for high-throughput analytical methods for fast and accurate analysis started with the separation of molecules based on different size, charge and hydrophobicity and with the introduction of chromatographic and electrophoretic methods into clinical laboratories. The next step was their optimization towards the strategy for a fast analysis and miniaturization. One of the main tools for such kinds of analyses are different optimized supports and instruments for signal amplification that are used in such devices. The discovery and use of miniaturized chromatographic and electrophoretic systems based on monolithic supports was briefly discussed here. Their development in the direction of further miniaturization towards biosensors and nanobiosensors was also presented.
Footnotes
1
ESF Forward Look (2012).
 
2
Bošnjak et al. (2008).
 
3
Pavelić et al. (2016).
 
4
The Royal Swedish Academy of Sciences (2002).
 
5
Josić and Andjelković (2016).
 
6
Nobel Lectures Chemistry (1964).
 
7
Axén and Porath (1966).
 
8
Johansson et al. (1975).
 
9
Unger (1979) and Chang et al. (1976).
 
10
Josić et al. (1989).
 
11
Tennikova et al. (1990).
 
12
Hjertén et al. (1989).
 
13
Josić et al. (1992).
 
14
Josić et al. (1992) and Svec and Huber (2006).
 
15
Svec and Huber (2006) and Josić and Buchacher (2001).
 
16
Štrancar et al. (1996).
 
17
Podgornik et al. (2000).
 
18
Wu et al. (2001) and Švec and Lv (2015).
 
19
Ručević et al. (2006) and Opal et al. (2007).
 
20
Josić and Buchacher (2001).
 
21
Opal et al. (2007) and Chaaban et al. (2015).
 
22
Breen et al. (2012).
 
23
Pučić et al. (2011).
 
24
Brgles et al. (2011).
 
25
Burke et al. (1988).
 
26
Veeraragavan et al. (1991) and Manseth et al. (2004).
 
27
Husband et al. (2000).
 
28
Veeraragavan et al. (1991).
 
29
Manseth et al. (2004).
 
30
Brgles et al. (2011) and Šrajer Gajdošik et al. (2012).
 
31
Ahrends et al. (2010), Kotasinska et al. (2012) and Trusch et al. (2012).
 
32
Shu et al. (2012).
 
33
Šrajer Gajdošik et al. (2014).
 
34
Burnouf (2007).
 
35
Burnouf (2007) and Josić et al. (2000).
 
36
Cho (2015).
 
37
Schiel et al. (2011).
 
38
Černigoj et al. (2015).
 
39
Brown et al. (2010).
 
40
Brgles et al. (2011).
 
41
Brgles et al. (2011), Šrajer Gajdošik et al. (2012), Ahrends et al. (2010), Kotasinska et al. (2012), Trusch et al. (2012) and Josić and Clifton (2007).
 
42
Josić et al. (1992) and Abou-Rebyeh et al. (1991).
 
43
Štrancar et al. (1996).
 
44
Svec and Fréchet (1996).
 
45
Brgles et al. (2011), Ahrends et al. (2010) and Šrajer Gajdošik et al. (2014).
 
46
Ahrends et al. (2010).
 
47
Josić and Clifton (2007).
 
48
Trbojević-Akmačić et al. (2016).
 
49
Naldi et al. (2017).
 
50
Breen et al. (2012), Pučić et al. (2011), Naldi et al. (2017) and Breen et al. (2016).
 
51
Peterson et al. (2002).
 
52
Makaram et al. (2014).
 
53
Nayak et al. (2017).
 
54
Wang (2008).
 
55
Nayak et al. (2017), Wang (2008) and Witkowska Nery et al. (2016).
 
56
Zang et al. (2004).
 
57
Chen et al. (2013).
 
58
Sheng et al. (2012).
 
59
Odom et al. (2013).
 
60
Lusczek et al. (2017).
 
61
Champagne et al. (2016).
 
62
Cavally et al. (2017).
 
63
Vander Heiden et al. (2009).
 
64
Nayak et al. (2017), Du and Dong (2017) and Liu et al. (2010).
 
65
Wang (2008) and Witkowska Nery et al. (2016).
 
66
Clark et al. (2016).
 
67
Alves et al. (2016).
 
68
Zamperi et al. (2017) and Švec and Lv (2015).
 
69
Fu et al. (2017), Du and Dong (2017) and Ashley et al. (2017).
 
70
Wen et al. (2017).
 
71
Yang et al. (2017).
 
72
Du and Dong (2017).
 
73
Ashley et al. (2017).
 
74
Ručević et al. (2006).
 
75
Švec and Lv (2015) and Malik et al. (2013).
 
76
Huang et al. (2016a).
 
77
Fu et al. (2017).
 
78
Nayak et al. (2017), Wang (2008) and Witkowska Nery et al. (2016).
 
79
Wang (2008).
 
80
Witkowska Nery et al. (2016).
 
81
Lupinek et al. (2014).
 
82
Lupinek et al. (2014).
 
83
Huang et al. (2016a).
 
84
Huang et al. (2016b).
 
85
Zhong et al. (2016).
 
86
Fu et al. (2017).
 
87
Du and Dong (2017).
 
88
Wen et al. (2017).
 
89
Jianrong et al. (2004).
 
90
MacKenzie et al. (2009) and Zeng et al. (2011).
 
91
Malik et al. (2013) and Jianrong et al. (2004).
 
92
MacKenzie et al. (2009) and Zeng et al. (2011).
 
93
Tiwari and Turner (2014).
 
Literature
go back to reference Abou-Rebyeh H, Körber F, Schubert-Rehberg K, Reusch J, Josić D (1991) Carrier membrane as a stationary phase for affinity chromatography and kinetic studies of membrane bound enzymes. J Chromatogr B 566:341–350 CrossRef Abou-Rebyeh H, Körber F, Schubert-Rehberg K, Reusch J, Josić D (1991) Carrier membrane as a stationary phase for affinity chromatography and kinetic studies of membrane bound enzymes. J Chromatogr B 566:341–350 CrossRef
go back to reference Ahrends R, Lichtner B, Bertsch A, Kohlbacher O, Hildebrand D, Trusch M, Schlüter H (2010) Application of displacement chromatography for the proteome analysis of a human plasma protein fraction. J Chromatogr A 1217:3321–3329 CrossRef Ahrends R, Lichtner B, Bertsch A, Kohlbacher O, Hildebrand D, Trusch M, Schlüter H (2010) Application of displacement chromatography for the proteome analysis of a human plasma protein fraction. J Chromatogr A 1217:3321–3329 CrossRef
go back to reference Alves RC, Barroso MF, González-García MB, Oliveira MB, Delerue-Matos C (2016) New trends in food allergens detection: toward biosensing strategies. Crit Rev Food Sci Nutr 56:2304–2319 CrossRef Alves RC, Barroso MF, González-García MB, Oliveira MB, Delerue-Matos C (2016) New trends in food allergens detection: toward biosensing strategies. Crit Rev Food Sci Nutr 56:2304–2319 CrossRef
go back to reference Ashley J, Piekarska M, Segers C, Trinth L, Rodgers T, Willey R, Tothill IE (2017) An SPR based sensor for allergens detection. Biosens Bioelectron 88:109–113 CrossRef Ashley J, Piekarska M, Segers C, Trinth L, Rodgers T, Willey R, Tothill IE (2017) An SPR based sensor for allergens detection. Biosens Bioelectron 88:109–113 CrossRef
go back to reference Axén R, Porath J (1966) Chemical coupling of enzymes to cross-linked dextran (“Sephadex”). Nature 210:367–369 CrossRef Axén R, Porath J (1966) Chemical coupling of enzymes to cross-linked dextran (“Sephadex”). Nature 210:367–369 CrossRef
go back to reference Bošnjak H, Pavelić K, Kraljević Pavelić S (2008) Towards preventive medicine. High-throughput methods from molecular biology are about to change daily clinical practice. EMBO Rep 9:1056–1060 CrossRef Bošnjak H, Pavelić K, Kraljević Pavelić S (2008) Towards preventive medicine. High-throughput methods from molecular biology are about to change daily clinical practice. EMBO Rep 9:1056–1060 CrossRef
go back to reference Breen L, Cao L, Eom L, Šrajer Gajdošik M, Camara L, Giacometti J, Dupuy D, Josić D (2012) High-throughput fractionation of human plasma for fast enrichment of low- and high-abundance proteins. Blood Trans 10(Suppl 2):S89–S100 Breen L, Cao L, Eom L, Šrajer Gajdošik M, Camara L, Giacometti J, Dupuy D, Josić D (2012) High-throughput fractionation of human plasma for fast enrichment of low- and high-abundance proteins. Blood Trans 10(Suppl 2):S89–S100
go back to reference Breen L, Pučić-Baković M, Vučković F, Reiding K, Trbojević-Akmačić I, Šrajer Gajdošik M, Cook MI, Lopez M, Wuhrer M, Camara LM, Andjelković U, Dupuy DE, Josić D (2016) IgG and IgM glycosylation patterns in patients undergoing image-guided tumor ablation. Biochim Biophys Acta Gen Subj 1860:1786–1794 CrossRef Breen L, Pučić-Baković M, Vučković F, Reiding K, Trbojević-Akmačić I, Šrajer Gajdošik M, Cook MI, Lopez M, Wuhrer M, Camara LM, Andjelković U, Dupuy DE, Josić D (2016) IgG and IgM glycosylation patterns in patients undergoing image-guided tumor ablation. Biochim Biophys Acta Gen Subj 1860:1786–1794 CrossRef
go back to reference Brgles M, Clifton J, Walsh R, Huang F, Ručević M, Cao L, Hixson D, Müller E, Josić D (2011) Selectivity of monolithic supports under overloading conditions and their use for separation of human plasma and isolation of low abundance proteins. J Chromatogr A 1218:2389–2395 CrossRef Brgles M, Clifton J, Walsh R, Huang F, Ručević M, Cao L, Hixson D, Müller E, Josić D (2011) Selectivity of monolithic supports under overloading conditions and their use for separation of human plasma and isolation of low abundance proteins. J Chromatogr A 1218:2389–2395 CrossRef
go back to reference Brown A, Bill J, Tully T, Radhamohan A, Dowd C (2010) Overloading ion-exchange membranes as a purification step for monoclonal antibodies. Biotechnol Appl Biochem 56:59–70 CrossRef Brown A, Bill J, Tully T, Radhamohan A, Dowd C (2010) Overloading ion-exchange membranes as a purification step for monoclonal antibodies. Biotechnol Appl Biochem 56:59–70 CrossRef
go back to reference Burke LTW, Mant CT, Hodges RS (1988) A novel approach to reversed-phase preparative high-performance liquid chromatography of peptides. J Liq Chromat 11:1229–1247 CrossRef Burke LTW, Mant CT, Hodges RS (1988) A novel approach to reversed-phase preparative high-performance liquid chromatography of peptides. J Liq Chromat 11:1229–1247 CrossRef
go back to reference Burnouf T (2007) Modern plasma fractionation. Transfusion Med Rev 21:101–117 CrossRef Burnouf T (2007) Modern plasma fractionation. Transfusion Med Rev 21:101–117 CrossRef
go back to reference Cavally G, Justice JN, Boyle KE, D’Alessandro A, Eisenmesser EZ, Herrera JJ (2017) Interleukin 37 reverses the metabolic cost of inflammation, increases oxidative respiration, and improves exercise tolerance. Proc Natl Acad Sci USA 114:2313–2318 CrossRef Cavally G, Justice JN, Boyle KE, D’Alessandro A, Eisenmesser EZ, Herrera JJ (2017) Interleukin 37 reverses the metabolic cost of inflammation, increases oxidative respiration, and improves exercise tolerance. Proc Natl Acad Sci USA 114:2313–2318 CrossRef
go back to reference Černigoj U, Martinuč U, Cardoso S, Sekirnik R, Lendero Kranjc N, Štrancar A (2015) Sample displacement chromatography of plasmid DNA forms. J Chromatogr A 1414:103–109 CrossRef Černigoj U, Martinuč U, Cardoso S, Sekirnik R, Lendero Kranjc N, Štrancar A (2015) Sample displacement chromatography of plasmid DNA forms. J Chromatogr A 1414:103–109 CrossRef
go back to reference Chaaban H, Keshari RS, Silasi-Mansat R, Popescu NI, Mehta-D’Souza P, Lim Y-P, Lupu F (2015) Inter-α-inhibitor protein and its associated glycosaminolglycans protect against histone-induced injury. Blood 125:2286–2296 CrossRef Chaaban H, Keshari RS, Silasi-Mansat R, Popescu NI, Mehta-D’Souza P, Lim Y-P, Lupu F (2015) Inter-α-inhibitor protein and its associated glycosaminolglycans protect against histone-induced injury. Blood 125:2286–2296 CrossRef
go back to reference Champagne DP, Hatle KM, Fortner KA, D’Alessandro A, Thornton TM, Yang R, Torraba D, Tomás-Cortázar J, Jun YW, Ahn KH, Hansen KC, Haynes L, Anguita J, Rincon M (2016) Fine tuning of CD8 (+) T cell mitochondrial metabolism by the respiratory chain repressor MCJ dictates protection to influenza virus. Immunity 44:1299–1311 CrossRef Champagne DP, Hatle KM, Fortner KA, D’Alessandro A, Thornton TM, Yang R, Torraba D, Tomás-Cortázar J, Jun YW, Ahn KH, Hansen KC, Haynes L, Anguita J, Rincon M (2016) Fine tuning of CD8 (+) T cell mitochondrial metabolism by the respiratory chain repressor MCJ dictates protection to influenza virus. Immunity 44:1299–1311 CrossRef
go back to reference Chang S-H, Noel R, Regnier FE (1976) High speed ion exchange chromatography of proteins. Anal Chem 48:1839–1845 CrossRef Chang S-H, Noel R, Regnier FE (1976) High speed ion exchange chromatography of proteins. Anal Chem 48:1839–1845 CrossRef
go back to reference Chen P, Peng Y, He M, Yan X-C, Zhang Y, Liu X-N (2013) Sensitive electrochemical detection of creatinine at disposable screnn-printed carbon electrode mixed with ferrocenemethanol. Int J Electrochem Sci 8:8931–8939 Chen P, Peng Y, He M, Yan X-C, Zhang Y, Liu X-N (2013) Sensitive electrochemical detection of creatinine at disposable screnn-printed carbon electrode mixed with ferrocenemethanol. Int J Electrochem Sci 8:8931–8939
go back to reference Cho W (2015) Displacement phenomena in lectin affinity chromatography. Anal Chem 87:9612–9620 CrossRef Cho W (2015) Displacement phenomena in lectin affinity chromatography. Anal Chem 87:9612–9620 CrossRef
go back to reference Clark KD, Zhang C, Anderson JL (2016) Sample preparation for bioanalytical and pharmaceutical analysis. Anal Chem 88:11262–11270 CrossRef Clark KD, Zhang C, Anderson JL (2016) Sample preparation for bioanalytical and pharmaceutical analysis. Anal Chem 88:11262–11270 CrossRef
go back to reference Du Y, Dong S (2017) Nucleic acid biosensors: recent advances and perspectives. Anal Chem 89:189–215 CrossRef Du Y, Dong S (2017) Nucleic acid biosensors: recent advances and perspectives. Anal Chem 89:189–215 CrossRef
go back to reference ESF Forward Look (2012) Personalised medicine for the European citizen. Towards more precise medicine for the diagnosis, treatment and prevention of disease (iPM). European Science Foundation, Strasbourg ESF Forward Look (2012) Personalised medicine for the European citizen. Towards more precise medicine for the diagnosis, treatment and prevention of disease (iPM). European Science Foundation, Strasbourg
go back to reference Fu X, Chen L, Choo J (2017) Optical probes for ultrasensitive immunoassay. Anal Chem 89:124–137 CrossRef Fu X, Chen L, Choo J (2017) Optical probes for ultrasensitive immunoassay. Anal Chem 89:124–137 CrossRef
go back to reference Hjertén S, Liao JL, Zhang R (1989) High-performance liquid chromatography on continuous polymer beds. J Chromatogr A 473:273–275 CrossRef Hjertén S, Liao JL, Zhang R (1989) High-performance liquid chromatography on continuous polymer beds. J Chromatogr A 473:273–275 CrossRef
go back to reference Huang X, Aguilar ZP, Xu H, Li W, Xiong Y (2016a) Membrane-based lateral flow immunochromatograhic strip with nanoparticles as reporters for detection: a review. Biosens Bioelctron 75:166–180 CrossRef Huang X, Aguilar ZP, Xu H, Li W, Xiong Y (2016a) Membrane-based lateral flow immunochromatograhic strip with nanoparticles as reporters for detection: a review. Biosens Bioelctron 75:166–180 CrossRef
go back to reference Huang H, Jiang D, Zhu P, Pi F, Ji J, Sun C, Sun J, Sun X (2016b) A novel mast cell co-culture microfluidic chip for the electrochemical evaluation of food allergen. Biosens Bioelctron 83:126–133 CrossRef Huang H, Jiang D, Zhu P, Pi F, Ji J, Sun C, Sun J, Sun X (2016b) A novel mast cell co-culture microfluidic chip for the electrochemical evaluation of food allergen. Biosens Bioelctron 83:126–133 CrossRef
go back to reference Husband DL, Mant CT, Hodges RS (2000) Development of simultaneous purification methodology for multiple synthetic peptides by reversed-phase sample displacement chromatography. J Chromatogr A 893:81–94 CrossRef Husband DL, Mant CT, Hodges RS (2000) Development of simultaneous purification methodology for multiple synthetic peptides by reversed-phase sample displacement chromatography. J Chromatogr A 893:81–94 CrossRef
go back to reference Jain KK (2008) The handbook of nanomedicine. Humana Press, Basel, pp 91–116 Jain KK (2008) The handbook of nanomedicine. Humana Press, Basel, pp 91–116
go back to reference Jianrong C, Yuging M, Nongyne H, Xiaohua W, Sijiao L (2004) Nanotechnology and biosensors. Biotech Adv 22:505–518 CrossRef Jianrong C, Yuging M, Nongyne H, Xiaohua W, Sijiao L (2004) Nanotechnology and biosensors. Biotech Adv 22:505–518 CrossRef
go back to reference Johansson KE, Blomqvist J, Hjertén S (1975) Purification of membrane proteins from Acholeplasma laidlawii by agarose suspension electrophoresis in Tween 20 and polyacrylamide and dextran gel electrophoresis in detergent-free media. J Biol Chem 250:2463–2469 Johansson KE, Blomqvist J, Hjertén S (1975) Purification of membrane proteins from Acholeplasma laidlawii by agarose suspension electrophoresis in Tween 20 and polyacrylamide and dextran gel electrophoresis in detergent-free media. J Biol Chem 250:2463–2469
go back to reference Josić D, Andjelković U (2016) The role of proteomics in personalized medicine. In: Bodiroga-Vukobrat N, Pavelić K, Rukavina D, Sander GG (eds) Personalised medicine: a new medical and social challenge (Europeanization and globalization). Springer International Publishing, Switzerland, pp 179–218 CrossRef Josić D, Andjelković U (2016) The role of proteomics in personalized medicine. In: Bodiroga-Vukobrat N, Pavelić K, Rukavina D, Sander GG (eds) Personalised medicine: a new medical and social challenge (Europeanization and globalization). Springer International Publishing, Switzerland, pp 179–218 CrossRef
go back to reference Josić D, Buchacher A (2001) Application of monoliths as supports for affinity chromatography and fast enzymatic conversion. J Biochem Biophys Methods 49:153–174 CrossRef Josić D, Buchacher A (2001) Application of monoliths as supports for affinity chromatography and fast enzymatic conversion. J Biochem Biophys Methods 49:153–174 CrossRef
go back to reference Josić D, Clifton JG (2007) Use of monolithic supports in proteomics technology. J Chromatogr A 1144:2–13 CrossRef Josić D, Clifton JG (2007) Use of monolithic supports in proteomics technology. J Chromatogr A 1144:2–13 CrossRef
go back to reference Josić D, Zeilinger K, Lim Y-P, Raps M, Hofmann W, Reutter W (1989) Preparative isolation of glycoproteins from plasma membranes of different rat organs. J Chromatogr A 484:327–335 CrossRef Josić D, Zeilinger K, Lim Y-P, Raps M, Hofmann W, Reutter W (1989) Preparative isolation of glycoproteins from plasma membranes of different rat organs. J Chromatogr A 484:327–335 CrossRef
go back to reference Josić D, Reusch J, Löster K, Baum O, Reutter W (1992) High performance membrane chromatography of serum and plasma membrane proteins. J Chromatogr A 590:59–76 CrossRef Josić D, Reusch J, Löster K, Baum O, Reutter W (1992) High performance membrane chromatography of serum and plasma membrane proteins. J Chromatogr A 590:59–76 CrossRef
go back to reference Josić D, Hoffer L, Buchacher A, Schwill F, Biesert L, Klöcking H-P, Hellstern P, Rokicka-Milewska R, Klukowska A (2000) Manufacturing of prothrombin complex concentrate aiming a low thrombinicity. Thromb Res 100:433–441 CrossRef Josić D, Hoffer L, Buchacher A, Schwill F, Biesert L, Klöcking H-P, Hellstern P, Rokicka-Milewska R, Klukowska A (2000) Manufacturing of prothrombin complex concentrate aiming a low thrombinicity. Thromb Res 100:433–441 CrossRef
go back to reference Kotasinska M, Richter W, Thiemann J, Schlüter H (2012) Cation exchange displacement batch chromatography of proteins guided by screening of protein purification parameters. Electrophoresis 35:3170–3176 Kotasinska M, Richter W, Thiemann J, Schlüter H (2012) Cation exchange displacement batch chromatography of proteins guided by screening of protein purification parameters. Electrophoresis 35:3170–3176
go back to reference Liu J, Chen C-F, Chang C-W, DeVoe DL (2010) Flow-through immunosensors using antibody-immobilized polymer monoliths. Biosens Bioelectron 26:182–188 CrossRef Liu J, Chen C-F, Chang C-W, DeVoe DL (2010) Flow-through immunosensors using antibody-immobilized polymer monoliths. Biosens Bioelectron 26:182–188 CrossRef
go back to reference Lupinek C, Wollmann E, Baar A, Banerjee S, Breiteneder H, Broecker BM et al (2014) Advances in allergen-microarray technology for diagnosis and monitoring of allergy: the MeDALL allergen-chip. Methods 66:106–119 CrossRef Lupinek C, Wollmann E, Baar A, Banerjee S, Breiteneder H, Broecker BM et al (2014) Advances in allergen-microarray technology for diagnosis and monitoring of allergy: the MeDALL allergen-chip. Methods 66:106–119 CrossRef
go back to reference Lusczek ER, Muratore SL, Dubick MA, Beilman J (2017) Assessment of key plasma metabolites in combat causalities. J Trauma Acute Care Surg 82:309–316 CrossRef Lusczek ER, Muratore SL, Dubick MA, Beilman J (2017) Assessment of key plasma metabolites in combat causalities. J Trauma Acute Care Surg 82:309–316 CrossRef
go back to reference MacKenzie R, Auzelyte V, Olliges S et al (2009) Nanowire development and characterization for applications in biosensing. In: Micheli G, Leblebici Y, Gijs M, Vörös J (eds) Nanosyst design & technology. Springer, pp 143–173 MacKenzie R, Auzelyte V, Olliges S et al (2009) Nanowire development and characterization for applications in biosensing. In: Micheli G, Leblebici Y, Gijs M, Vörös J (eds) Nanosyst design & technology. Springer, pp 143–173
go back to reference Makaram P, Owens D, Aceros J (2014) Trends in nanomaterial-based non-invasive diabetes sensing technologies. Diagnostica (Basel) 4:27–46 Makaram P, Owens D, Aceros J (2014) Trends in nanomaterial-based non-invasive diabetes sensing technologies. Diagnostica (Basel) 4:27–46
go back to reference Malik P, Katyal V, Malik V, Asatkar A, Inwati G, Mukherjee TK (2013) ISRN nanobiosensors: concepts and variations nanomaterials. Article ID 327435 Malik P, Katyal V, Malik V, Asatkar A, Inwati G, Mukherjee TK (2013) ISRN nanobiosensors: concepts and variations nanomaterials. Article ID 327435
go back to reference Manseth E, Skjervold PO, Flengsrud R (2004) Sample displacement chromatography of Atlantic Salmon (Salmo salar) thrombin. J Biochem Biophys Methods 60:39–47 CrossRef Manseth E, Skjervold PO, Flengsrud R (2004) Sample displacement chromatography of Atlantic Salmon (Salmo salar) thrombin. J Biochem Biophys Methods 60:39–47 CrossRef
go back to reference Naldi M, Černogoj U, Štrancar A, Bartolini M (2017) Towards automation in protein digestion: development of monolithic trypsin immobilized reactor for highly efficient on-line digestion and analysis. Talanta 167:143–157 CrossRef Naldi M, Černogoj U, Štrancar A, Bartolini M (2017) Towards automation in protein digestion: development of monolithic trypsin immobilized reactor for highly efficient on-line digestion and analysis. Talanta 167:143–157 CrossRef
go back to reference Nayak S, Blumenfeld NR, Laksanasopin T, Sia SK (2017) Point-of-care diagnostic: recent developments in connected age. Anal Chem 89:102–123 CrossRef Nayak S, Blumenfeld NR, Laksanasopin T, Sia SK (2017) Point-of-care diagnostic: recent developments in connected age. Anal Chem 89:102–123 CrossRef
go back to reference Nobel Lectures Chemistry 1942–1962 (1964) Elsevier, Amsterdam Nobel Lectures Chemistry 1942–1962 (1964) Elsevier, Amsterdam
go back to reference Odom SR, Howell MD, Silva GS, Nielsen VM, Grupta A, Shapiro NI, Talmor D (2013) Lactate clearance as a predictor of mortality in trauma patients. J Trauma Acute Care Surg 74:999–1004 CrossRef Odom SR, Howell MD, Silva GS, Nielsen VM, Grupta A, Shapiro NI, Talmor D (2013) Lactate clearance as a predictor of mortality in trauma patients. J Trauma Acute Care Surg 74:999–1004 CrossRef
go back to reference Opal SM, Lim Y-P, Siryaporn E, Moldawer LL, Pribble JP, Palardy JE, Souza S (2007) Longitudinal studies of inter-alpha inhibitor proteins in severely septic patients: a potential clinical marker and mediator of severe sepsis. Crit Care Med 35:387–392 CrossRef Opal SM, Lim Y-P, Siryaporn E, Moldawer LL, Pribble JP, Palardy JE, Souza S (2007) Longitudinal studies of inter-alpha inhibitor proteins in severely septic patients: a potential clinical marker and mediator of severe sepsis. Crit Care Med 35:387–392 CrossRef
go back to reference Pavelić K, Sedić M, Pavelić Kraljević S (2016) Introduction to personalized medicine. In: Bodiroga-Vukobrat N, Pavelić K, Rukavina D, Sander GG (eds) Personalised medicine: a new medical and social challenge (Europeanization and globalization). Springer International Publishing, Switzerland, pp 300–320 Pavelić K, Sedić M, Pavelić Kraljević S (2016) Introduction to personalized medicine. In: Bodiroga-Vukobrat N, Pavelić K, Rukavina D, Sander GG (eds) Personalised medicine: a new medical and social challenge (Europeanization and globalization). Springer International Publishing, Switzerland, pp 300–320
go back to reference Peterson DS, Rohr T, Svec F, Fréchet MJ (2002) Enzymatic microreactor-on-a-chip: protein mapping using trypsin immobilized on porous polymer monoliths moulded in channels of microfluidic devices. Anal Chem 74:4081–4088 CrossRef Peterson DS, Rohr T, Svec F, Fréchet MJ (2002) Enzymatic microreactor-on-a-chip: protein mapping using trypsin immobilized on porous polymer monoliths moulded in channels of microfluidic devices. Anal Chem 74:4081–4088 CrossRef
go back to reference Podgornik A, Barut M, Štrancar A, Josić D, Koloini T (2000) Construction of large-volume monolithic columns. Anal Chem 72:5693–5699 CrossRef Podgornik A, Barut M, Štrancar A, Josić D, Koloini T (2000) Construction of large-volume monolithic columns. Anal Chem 72:5693–5699 CrossRef
go back to reference Pučić M, Knežević A, Vidič J, Adamczyk B, Novoknet M, Polašek O (2011) High throughput isolation and glycosylation analysis of IgG-variability and heritability of the IgG glycome in three isolated human populations. Mol Cell Proteomics 10:M111.010090 CrossRef Pučić M, Knežević A, Vidič J, Adamczyk B, Novoknet M, Polašek O (2011) High throughput isolation and glycosylation analysis of IgG-variability and heritability of the IgG glycome in three isolated human populations. Mol Cell Proteomics 10:M111.010090 CrossRef
go back to reference Ručević M, Clifton JG, Huang F, Li X, Callanan H, Hixson DC, Josić D (2006) Use of short monolithic columns for isolation of low abundance membrane proteins. J Chromatogr A 1123:199–204 CrossRef Ručević M, Clifton JG, Huang F, Li X, Callanan H, Hixson DC, Josić D (2006) Use of short monolithic columns for isolation of low abundance membrane proteins. J Chromatogr A 1123:199–204 CrossRef
go back to reference Schiel JE, Tong Z, Sakulthaew C, Hage DS (2011) Development of a flow-based ultafast immunoextraction and reverse displacement immunoassay: analysis of free drug fractions. Anal Chem 83:9387–9390 CrossRef Schiel JE, Tong Z, Sakulthaew C, Hage DS (2011) Development of a flow-based ultafast immunoextraction and reverse displacement immunoassay: analysis of free drug fractions. Anal Chem 83:9387–9390 CrossRef
go back to reference Sheng Z-H, Zheng X-Q, Xu J-Y, Bao W-J, Wang F-B, Xia X-H (2012) Electrochemical sensor based on nitrogen doped graphene: simultaneous determination of ascorbic acid, dopamine and uric acid. Biosens Biolectron 34:125–131 CrossRef Sheng Z-H, Zheng X-Q, Xu J-Y, Bao W-J, Wang F-B, Xia X-H (2012) Electrochemical sensor based on nitrogen doped graphene: simultaneous determination of ascorbic acid, dopamine and uric acid. Biosens Biolectron 34:125–131 CrossRef
go back to reference Shu Q-H, Shi Z-C, Sun Y (2012) Dynamic behavior of binary component ion-exchange displacement chromatography of proteins visualized by confocal laser scanning microscopy. J Chromatogr A 1257:48–57 CrossRef Shu Q-H, Shi Z-C, Sun Y (2012) Dynamic behavior of binary component ion-exchange displacement chromatography of proteins visualized by confocal laser scanning microscopy. J Chromatogr A 1257:48–57 CrossRef
go back to reference Šrajer Gajdošik M, Clifton J, Josić D (2012) Sample displacement chromatography as a method for purification of proteins and peptides from complex mixtures. J Chromatogr A 1239:1–9 CrossRef Šrajer Gajdošik M, Clifton J, Josić D (2012) Sample displacement chromatography as a method for purification of proteins and peptides from complex mixtures. J Chromatogr A 1239:1–9 CrossRef
go back to reference Šrajer Gajdošik M, Kovač S, Malatesti N, Müller E, Josić D (2014) Ion-exchange sample displacement chromatography as a method for fast and simple isolation of low- and high-abundance proteins from complex biological mixtures. Food Technol Biotechnol 52:58–63 Šrajer Gajdošik M, Kovač S, Malatesti N, Müller E, Josić D (2014) Ion-exchange sample displacement chromatography as a method for fast and simple isolation of low- and high-abundance proteins from complex biological mixtures. Food Technol Biotechnol 52:58–63
go back to reference Štrancar A, Koselj P, Schwinn H, Josić D (1996) Application of compact, porous disks for fast separation of biopolymers and in-process control in biotechnology. Anal Chem 68:3483–3488 CrossRef Štrancar A, Koselj P, Schwinn H, Josić D (1996) Application of compact, porous disks for fast separation of biopolymers and in-process control in biotechnology. Anal Chem 68:3483–3488 CrossRef
go back to reference Svec F, Fréchet JM (1996) New designs of macroporous polymers and supports: from separation to biocatalysis. Science 273:205–211 CrossRef Svec F, Fréchet JM (1996) New designs of macroporous polymers and supports: from separation to biocatalysis. Science 273:205–211 CrossRef
go back to reference Svec F, Huber F (2006) Monolithic materials: promises, challenges, achievements. Anal Chem 78:2101–2107 CrossRef Svec F, Huber F (2006) Monolithic materials: promises, challenges, achievements. Anal Chem 78:2101–2107 CrossRef
go back to reference Švec F, Lv Y (2015) Advances and recent trends in the field of monolithic columns for chromatography. Anal Chem 87:250–273 CrossRef Švec F, Lv Y (2015) Advances and recent trends in the field of monolithic columns for chromatography. Anal Chem 87:250–273 CrossRef
go back to reference Tennikova TB, Svec F, Belenkii BG (1990) High performance membrane chromatography. A novel method for protein separation. J Liquid Chromatogr 13:63–70 CrossRef Tennikova TB, Svec F, Belenkii BG (1990) High performance membrane chromatography. A novel method for protein separation. J Liquid Chromatogr 13:63–70 CrossRef
go back to reference Tiwari A, Turner PF (eds) (2014) Biosensors nanotehnology. Wiley, Scrivene Publishing, USA Tiwari A, Turner PF (eds) (2014) Biosensors nanotehnology. Wiley, Scrivene Publishing, USA
go back to reference Trbojević-Akmačić I, Nemec B, Vidič U, Malić S, Miklić K, Černogoj U, Vidič J, Lendero Kranjc N, Štrancar A, Lauc G, Lenac Roviš T, Pučić-Baković M (2016) Chromatographic monoliths for high-throughput immunoaffinity isolation of transferrin from human plasma. Croat Chem Acta 89:203–211 CrossRef Trbojević-Akmačić I, Nemec B, Vidič U, Malić S, Miklić K, Černogoj U, Vidič J, Lendero Kranjc N, Štrancar A, Lauc G, Lenac Roviš T, Pučić-Baković M (2016) Chromatographic monoliths for high-throughput immunoaffinity isolation of transferrin from human plasma. Croat Chem Acta 89:203–211 CrossRef
go back to reference Trusch M, Tillack K, Kwiatkowski M, Bertsch A, Ahrends R, Kohlbacher O, Martin R, Sospedra M, Schlüter H (2012) Displacement chromatography as a first separating step in online two-dimensional chromatography coupled to mass spectrometry analysis of complex protein sample – the proteome of neutrophils. J Chromatogr A 1232:288–294 CrossRef Trusch M, Tillack K, Kwiatkowski M, Bertsch A, Ahrends R, Kohlbacher O, Martin R, Sospedra M, Schlüter H (2012) Displacement chromatography as a first separating step in online two-dimensional chromatography coupled to mass spectrometry analysis of complex protein sample – the proteome of neutrophils. J Chromatogr A 1232:288–294 CrossRef
go back to reference Unger KK (1979) Porous silica: its properties and use in column liquid chromatography. J Chromatogr Library, Elsevier Unger KK (1979) Porous silica: its properties and use in column liquid chromatography. J Chromatogr Library, Elsevier
go back to reference Vander Heiden MG, Cantley LC, Thompson B (2009) Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 324:1029–1033 CrossRef Vander Heiden MG, Cantley LC, Thompson B (2009) Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 324:1029–1033 CrossRef
go back to reference Veeraragavan K, Bernier A, Braendli E (1991) Sample displacement mode chromatography: purification of proteins by use of a high-performance anion-exchange column. J Chromatogr A 541:207–220 CrossRef Veeraragavan K, Bernier A, Braendli E (1991) Sample displacement mode chromatography: purification of proteins by use of a high-performance anion-exchange column. J Chromatogr A 541:207–220 CrossRef
go back to reference Wen W, Yan X, Zhu C, Du D, Lin Y (2017) Recent advances in electrochemical immunoassays. Anal Chem 89:138–156 CrossRef Wen W, Yan X, Zhu C, Du D, Lin Y (2017) Recent advances in electrochemical immunoassays. Anal Chem 89:138–156 CrossRef
go back to reference Witkowska Nery E, Kundys M, Jeleń PS, Jönsson-Niedziółka M (2016) Electrochemical glucose sensing: is there still room for improvement. Anal Chem 88:11271–11282 CrossRef Witkowska Nery E, Kundys M, Jeleń PS, Jönsson-Niedziółka M (2016) Electrochemical glucose sensing: is there still room for improvement. Anal Chem 88:11271–11282 CrossRef
go back to reference Wu C, Davey MH, Svec F, Fréchet MJ (2001) Monolithic porous polymer for on-chip solid phase extraction and preconcentration prepared by photoinitiated in situ polymerization within a microfluidic device. Anal Chem 71:5088–5096 Wu C, Davey MH, Svec F, Fréchet MJ (2001) Monolithic porous polymer for on-chip solid phase extraction and preconcentration prepared by photoinitiated in situ polymerization within a microfluidic device. Anal Chem 71:5088–5096
go back to reference Yang Y, Noviana E, Nguyen MP, Geiss BJ, Dandy DS, Henry CS (2017) Paper-based microfluidic devices: emerging themes and applications. Anal Chem 89:71–91 CrossRef Yang Y, Noviana E, Nguyen MP, Geiss BJ, Dandy DS, Henry CS (2017) Paper-based microfluidic devices: emerging themes and applications. Anal Chem 89:71–91 CrossRef
go back to reference Zamperi M, Sekar K, Zamboni N, Sauer U (2017) Frontiers of high-throughput metabolomics. Curr Opin Chem Biol 36:15–23 CrossRef Zamperi M, Sekar K, Zamboni N, Sauer U (2017) Frontiers of high-throughput metabolomics. Curr Opin Chem Biol 36:15–23 CrossRef
go back to reference Zang F, Wang X, Ai S, Sun Z, Wan Q, Zhu Z, Xian Y, Jin L, Yamamoto K (2004) Immobilization of uricase on ZnO nanorods for a reagentless uric acid biosensor. Anal Chim Acta 519:155–160 CrossRef Zang F, Wang X, Ai S, Sun Z, Wan Q, Zhu Z, Xian Y, Jin L, Yamamoto K (2004) Immobilization of uricase on ZnO nanorods for a reagentless uric acid biosensor. Anal Chim Acta 519:155–160 CrossRef
go back to reference Zeng S, Yong K-T, Roy I, Dinh X-Q, Yu X, Luan F (2011) A review on functionalized gold nanoparticles for biosensing applications. Plasmonics 6:491–506 CrossRef Zeng S, Yong K-T, Roy I, Dinh X-Q, Yu X, Luan F (2011) A review on functionalized gold nanoparticles for biosensing applications. Plasmonics 6:491–506 CrossRef
go back to reference Zhong X, Qiao L, Gasilova N, Liu B, Girault HH (2016) Mass barcode signal amplification for multiplex allergy diagnosis by MALDI-MS. Anal Chem 88:6184–6189 CrossRef Zhong X, Qiao L, Gasilova N, Liu B, Girault HH (2016) Mass barcode signal amplification for multiplex allergy diagnosis by MALDI-MS. Anal Chem 88:6184–6189 CrossRef
Metadata
Title
High-Throughput Analytics in the Function of Personalized Medicine
Authors
Djuro Josić
Tamara Martinović
Urh Černigoj
Jana Vidič
Krešimir Pavelić
Copyright Year
2019
DOI
https://doi.org/10.1007/978-3-030-16465-2_6

Premium Partner