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2022 | OriginalPaper | Chapter

Hybrid Nanostructures for Biomedical Applications

Authors : R. Rajakumari, Abhimanyu Tharayil, Sabu Thomas, Nandakumar Kalarikkal

Published in: Hybrid Phosphor Materials

Publisher: Springer International Publishing

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Abstract

Nanoparticles have great potential in the biomedical field owing to its superior properties. Hybrid nanomaterials can be used to perform both diagnostic and therapeutic function by a single system. These materials will have the synergistic beneficial features of the different nanomaterials incorporated. In this chapter, we have categorised the inorganic/organic hybrid nanomaterials which are being developed in the field of biomedical applications. In addition, summarized the most recently reported hybrid nanomaterials, nanoparticles and nanocomposites with their synthesis methods and physicochemical properties. This chapter will summarize the recent advances in the synthesis, design and applications of hybrid nanomaterials in the biomedical field. The applications especially the imaging, drug delivery and cancer therapeutic applications will be highlighted.

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Qiu, L.Y., Bae, Y.H.: Polymer architecture and drug delivery. Pharm. Res. 23, 1–30 (2006)CrossRef

Huebsch, N., Mooney, D.J.: Inspiration and application in the evolution of biomaterials. Nature 462, 426–432 (2009)CrossRef

Bobo, D., Robinson, K.J., Islam, J., Thurecht, K.J., Corrie, S.R.: Nanoparticle-based medicines: a review of FDA-approved materials and clinical trials to date. Pharm. Res. 33, 2373–2387 (2016)CrossRef

Allen, T.M., Cullis, P.R.: Drug delivery systems: entering the mainstream. Science 303(80), 1818–1822 (2004)

Ramakrishna, S., Mayer, J., Wintermantel, E., Leong, K.W.: Biomedical applications of polymer-composite materials: a review. Compos. Sci. Technol. 61, 1189–1224 (2001)CrossRef

Nicole, L., Rozes, L., Sanchez, C.: Integrative approaches to hybrid multifunctional materials: from multidisciplinary research to applied technologies. Adv. Mater. 22, 3208–3214 (2010)CrossRef

Mir, S.H., Nagahara, L.A., Thundat, T., Mokarian-Tabari, P., Furukawa, H., Khosla, A.: Organic-inorganic hybrid functional materials: an integrated platform for applied technologies. J. Electrochem. Soc. 165, B3137 (2018)CrossRef

Ling, D., Park, W., Park, Y.I., Lee, N., Li, F., Song, C., et al.: Multiple‐interaction ligands inspired by mussel adhesive protein: synthesis of highly stable and biocompatible nanoparticles. Angew. Chemie. Int. Ed. 50, 11360–11365 (2011)

Liu, H., Webster, T.J.: Mechanical properties of dispersed ceramic nanoparticles in polymer composites for orthopedic applications. Int. J. Nanomed. 5, 299 (2010)

10.

Hong, Z., Reis, R.L., Mano, J.F.: Preparation and in-vitro characterization of scaffolds of poly (l-lactic acid) containing bioactive glass ceramic nanoparticles. Acta Biomater. 4, 1297–1306 (2008)CrossRef

11.

Ates, B., Koytepe, S., Balcioglu, S., Ulu, A., Gurses, C.: Biomedical Applications of Hybrid Polymer Composite Materials. Elsevier Ltd (2017). https://doi.org/10.1016/B978-0-08-100785-3.00012-7

12.

Tsuru, K., Hayakawa, S., Osaka, A.: Medical Applications of Hybrid Materials. Weinheim. Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim (2007)

13.

Sanchez, C., Shea, K.J., Kitagawa, S.: Medical applications of organic–inorganic hybrid materials within the field of silica-based bioceramics. Chem. Soc. Rev. 40, 596–607 (2011). https://doi.org/10.1039/c0cs00025fCrossRef

14.

Chimene, D., Alge, D.L., Gaharwar, A.K.: Two-dimensional nanomaterials for biomedical applications: emerging trends and future prospects. Adv. Mater. 27, 7261–7284 (2015)CrossRef

15.

Adnan, M.M., Dalod, A.R.M., Balci, M.H., Glaum, J., Einarsrud, M.-A.: In-situ synthesis of hybrid inorganic–polymer nanocomposites. Polymers (Basel) 10, 1129 (2018)CrossRef

16.

Sanchez, C., Ribot, F., Lebeau, B.: Molecular design of hybrid organic-inorganic nanocomposites synthesized via sol-gel chemistry. J. Mater. Chem. 9, 35–44 (1999)CrossRef

17.

Daniel, M.-C., Astruc, D.: Gold nanoparticles: assembly, supramolecular chemistry, quantum-size-related properties, and applications toward biology, catalysis, and nanotechnology. Chem. Rev. 104, 293–346 (2004)CrossRef

18.

Magdolenova, Z., Collins, A., Kumar, A., Dhawan, A., Stone, V., Dusinska, M.: Mechanisms of genotoxicity. A review of in-vitro and in-vivo studies with engineered nanoparticles. Nanotoxicology 8, 233–278 (2014)

19.

Kelly, K.L., Coronado, E., Zhao, L.L., Schatz, G.C.: The optical properties of metal nanoparticles: the influence of size, shape, and dielectric environment (2003)

20.

El-Sayed, M.A.: Small is different: shape-, size-, and composition-dependent properties of some colloidal semiconductor nanocrystals. Acc. Chem. Res. 37, 326–333 (2004)CrossRef

21.

Zhao, N., Yan, L., Zhao, X., Chen, X., Li, A., Zheng, D., et al.: Versatile types of organic/inorganic nanohybrids: from strategic design to biomedical applications. Chem. Rev. 119, 1666–1762 (2018)CrossRef

22.

Vallet-Regí, M., Colilla, M., González, B.: Medical applications of organic–inorganic hybrid materials within the field of silica-based bioceramics. Chem. Soc. Rev. 40, 596–607 (2011)CrossRef

23.

Oun, A.A., Shankar, S., Rhim, J.-W.: Multifunctional nanocellulose/metal and metal oxide nanoparticle hybrid nanomaterials. Crit. Rev. Food Sci. Nutr. 60, 435–460 (2020)CrossRef

24.

Liu, X., Zhang, Q., Knoll, W., Liedberg, B., Wang, Y.: Rational design of functional peptide-gold hybrid nanomaterials for molecular interactions. Adv. Mater. 32, 2000866 (2020)CrossRef

25.

Makvandi, P., Wang, C., Zare, E.N., Borzacchiello, A., Niu, L., Tay, F.R.: Metal‐based nanomaterials in biomedical applications: Antimicrobial activity and cytotoxicity aspects. Adv. Funct. Mater. 1910021 (2020)

26.

Park, W., Shin, H., Choi, B., Rhim, W.-K., Na, K., Han, D.K.: Advanced hybrid nanomaterials for biomedical applications. Prog. Mater. Sci. 100686 (2020)

27.

Xiao, M.-C., Chou, Y.-H., Hung, Y.-N., Hu, S.-H., Chiang, W.-H.: Hybrid polymeric nanoparticles with high zoledronic acid payload and proton sponge-triggered rapid drug release for anticancer applications. Mater. Sci. Eng. C 116, 111277 (2020)

28.

Pieretti, J.C., Rolim, W.R., Ferreira, F.F., Lombello, C.B., Nascimento, M.H.M., Seabra, A.B.: Synthesis, characterization, and cytotoxicity of Fe₃O₄@Ag hybrid nanoparticles: promising applications in cancer treatment. J. Clust. Sci. 31, 535–547 (2020)CrossRef

29.

Kango, S., Kalia, S., Celli, A., Njuguna, J., Habibi, Y., Kumar, R.: Surface modification of inorganic nanoparticles for development of organic–inorganic nanocomposites—a review. Prog. Polym. Sci. 38, 1232–1261 (2013)CrossRef

30.

Xie, Y., Hill, C.A.S., Xiao, Z., Militz, H., Mai, C.: Silane coupling agents used for natural fiber/polymer composites: a review. Compos. Part A. Appl. Sci. Manuf. 41, 806–819 (2010)CrossRef

31.

Hideshima, S., Hinou, H., Ebihara, D., Sato, R., Kuroiwa, S., Nakanishi, T., et al.: Attomolar detection of influenza A virus hemagglutinin human H1 and avian H5 using glycan-blotted field effect transistor biosensor. Anal. Chem. 85, 5641–5644 (2013)CrossRef

32.

Basuki, J.S., Esser, L., Zetterlund, P.B., Whittaker, M.R., Boyer, C., Davis, T.P.: Grafting of P (OEGA) onto magnetic nanoparticles using Cu(0) mediated polymerization: comparing grafting “from” and “to” approaches in the search for the optimal material design of nanoparticle MRI contrast agents. Macromolecules 46, 6038–6047 (2013)CrossRef

33.

Chatterjee, S., Karam, T.E., Rosu, C., Wang, C.-H., Youm, S.G., Li, X., et al.: Silica–conjugated polymer hybrid fluorescent nanoparticles: preparation by surface-initiated polymerization and spectroscopic studies. J. Phys. Chem. C 122, 6963–6975 (2018)CrossRef

34.

Chen, H., Wang, G.D., Chuang, Y.-J., Zhen, Z., Chen, X., Biddinger, P., et al.: Nanoscintillator-mediated X-ray inducible photodynamic therapy for in-vivo cancer treatment. Nano. Lett. 15, 2249–2256 (2015)CrossRef

35.

Tong, S., Hou, S., Zheng, Z., Zhou, J., Bao, G.: Coating optimization of superparamagnetic iron oxide nanoparticles for high T2 relaxivity. Nano. Lett. 10, 4607–4613 (2010)CrossRef

36.

Raula, J., Shan, J., Nuopponen, M., Niskanen, A., Jiang, H., Kauppinen, E.I., et al.: Synthesis of gold nanoparticles grafted with a thermoresponsive polymer by surface-induced reversible-addition-fragmentation chain-transfer polymerization. Langmuir 19, 3499–3504 (2003)CrossRef

37.

Pfaff, A., Schallon, A., Ruhland, T.M., Majewski, A.P., Schmalz, H., Freitag, R., et al.: Magnetic and fluorescent glycopolymer hybrid nanoparticles for intranuclear optical imaging. Biomacromol 12, 3805–3811 (2011)CrossRef

38.

Yan, J., Li, S., Cartieri, F., Wang, Z., Hitchens, T.K., Leonardo, J., et al.: Iron oxide nanoparticles with grafted polymeric analogue of dimethyl sulfoxide as potential magnetic resonance imaging contrast agents. ACS Appl. Mater. Interfaces 10, 21901–21908 (2018)CrossRef

39.

Kievit, F.M., Veiseh, O., Bhattarai, N., Fang, C., Gunn, J.W., Lee, D., et al.: PEI–PEG–chitosan-copolymer-coated iron oxide nanoparticles for safe gene delivery: synthesis, complexation, and transfection. Adv. Funct. Mater. 19, 2244–2251 (2009)CrossRef

40.

Cole, A.J., David, A.E., Wang, J., Galbán, C.J., Hill, H.L., Yang, V.C.: Polyethylene glycol modified, cross-linked starch-coated iron oxide nanoparticles for enhanced magnetic tumor targeting. Biomaterials 32, 2183–2193 (2011)CrossRef

41.

Liong, M., Shao, H., Haun, J.B., Lee, H., Weissleder, R.: Carboxymethylated polyvinyl alcohol stabilizes doped ferrofluids for biological applications. Adv. Mater. 22, 5168–5172 (2010)CrossRef

42.

Zhu, N., Ji, H., Yu, P., Niu, J., Farooq, M.U., Akram, M.W., et al.: Surface modification of magnetic iron oxide nanoparticles. Nanomaterials 8, 810 (2018)CrossRef

43.

Li, F., Lu, J., Kong, X., Hyeon, T., Ling, D.: Dynamic nanoparticle assemblies for biomedical applications. Adv Mater 29, 1605897 (2017)CrossRef

44.

Nie, Z., Petukhova, A., Kumacheva, E.: Properties and emerging applications of self-assembled structures made from inorganic nanoparticles. Nat. Nanotechnol. 5, 15–25 (2010)CrossRef

45.

Ling, D., Hackett, M.J., Hyeon, T.: Surface ligands in synthesis, modification, assembly and biomedical applications of nanoparticles. Nano. Today 9, 457–477 (2014)CrossRef

46.

Grzelczak, M., Vermant, J., Furst, E.M., Liz-Marzán, L.M.: Directed self-assembly of nanoparticles. ACS Nano 4, 3591–3605 (2010)CrossRef

47.

Ling, D., Lee, N., Hyeon, T.: Chemical synthesis and assembly of uniformly sized iron oxide nanoparticles for medical applications. Acc. Chem. Res. 48, 1276–1285 (2015)CrossRef

48.

Kim, J.S., Rieter, W.J., Taylor, K.M.L., An, H., Lin, W., Lin, W.: Self-assembled hybrid nanoparticles for cancer-specific multimodal imaging. J. Am. Chem. Soc. 129, 8962–8963 (2007)CrossRef

49.

Si, S., Raula, M., Paira, T.K., Mandal, T.K.: Reversible self-assembly of carboxylated peptide-functionalized gold nanoparticles driven by metal-ion coordination. Chem. Phys. Chem. 9, 1578–1584 (2008)CrossRef

50.

Klajn, R., Olson, M.A., Wesson, P.J., Fang, L., Coskun, A., Trabolsi, A., et al.: Dynamic hook-and-eye nanoparticle sponges. Nat. Chem. 1, 733–738 (2009)

51.

Prasad, S., Achazi, K., Böttcher, C., Haag, R., Sharma, S.K.: Fabrication of nanostructures through self-assembly of non-ionic amphiphiles for biomedical applications. RSC Adv. 7, 22121–22132 (2017)CrossRef

52.

Horcajada, P., Gref, R., Baati, T., Allan, P.K., Maurin, G., Couvreur, P., et al.: Metal–organic frameworks in biomedicine. Chem. Rev. 112, 1232–1268 (2012)CrossRef

53.

He, C., Liu, D., Lin, W.: Nanomedicine applications of hybrid nanomaterials built from metal–ligand coordination bonds: nanoscale metal–organic frameworks and nanoscale coordination polymers. Chem. Rev. 115, 11079–11108 (2015)CrossRef

54.

Moon, H.R., Lim, D.-W., Suh, M.P.: Fabrication of metal nanoparticles in metal–organic frameworks. Chem. Soc. Rev. 42, 1807–1824 (2013)CrossRef

55.

Wang, L., Zheng, M., Xie, Z.: Nanoscale metal–organic frameworks for drug delivery: a conventional platform with new promise. J. Mater. Chem. B 6, 707–717 (2018)CrossRef

56.

Wu, M., Yang, Y.: Metal–organic framework (MOF)-based drug/cargo delivery and cancer therapy. Adv. Mater. 29, 1606134 (2017)CrossRef

57.

Stock, N., Biswas, S.: Synthesis of metal-organic frameworks (MOFs): routes to various MOF topologies, morphologies, and composites. Chem. Rev. 112, 933–969 (2012)CrossRef

58.

Chen, B., Yang, Z., Zhu, Y., Xia, Y.: Zeolitic imidazolate framework materials: recent progress in synthesis and applications. J. Mater. Chem. A 2, 16811–16831 (2014)CrossRef

59.

Xuan, W., Zhu, C., Liu, Y., Cui, Y.: Mesoporous metal–organic framework materials. Chem. Soc. Rev. 41, 1677–1695 (2012)CrossRef

60.

Fang, J., Nakamura, H., Maeda, H.: The EPR effect: unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect. Adv. Drug Deliv. Rev. 63, 136–151 (2011)CrossRef

61.

Greish, K.: Enhanced Permeability and Retention (EPR) Effect for Anticancer Nanomedicine Drug Targeting, pp. 25–37. Springer, Cancer Nanotechnol. (2010)

62.

Nichols, J.W., Bae, Y.H.E.P.R.: Evidence and fallacy. J. Control Release 190, 451–464 (2014)CrossRef

63.

Koh, K., Wong-Foy, A.G., Matzger, A.J.: A crystalline mesoporous coordination copolymer with high microporosity. Angew. Chemie. Int. Ed. 47, 677–680 (2008)CrossRef

64.

Han, L., Qi, H., Zhang, D., Ye, G., Zhou, W., Hou, C., et al.: A facile and green synthesis of MIL-100 (Fe) with high-yield and its catalytic performance. New. J. Chem. 41, 13504–13509 (2017)CrossRef

65.

Miller, M.A., Wang, C.-Y., Merrill, G.N.: Experimental and theoretical investigation into hydrogen storage via spillover in IRMOF-8. J. Phys. Chem. C 113, 3222–3231 (2009)CrossRef

66.

Ishiwata, T., Furukawa, Y., Sugikawa, K., Kokado, K., Sada, K.: Transformation of metal–organic framework to polymer gel by cross-linking the organic ligands preorganized in metal–organic framework. J. Am. Chem. Soc. 135, 5427–5432 (2013)CrossRef

67.

Chen, X., Tong, R., Shi, Z., Yang, B., Liu, H., Ding, S., et al.: MOF nanoparticles with encapsulated autophagy inhibitor in controlled drug delivery system for antitumor. ACS Appl. Mater. Interfaces 10, 2328–2337 (2018)CrossRef

68.

He, C., Lu, K., Liu, D., Lin, W.: Nanoscale metal–organic frameworks for the co-delivery of cisplatin and pooled siRNAs to enhance therapeutic efficacy in drug-resistant ovarian cancer cells. J. Am. Chem. Soc. 136, 5181–5184 (2014)CrossRef

69.

Arun Kumar, S., Balasubramaniam, B., Bhunia, S., Jaiswal, M.K., Verma, K., Khademhosseini, A., et al.: Two‐dimensional metal organic frameworks for biomedical applications. Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol. e1674 (2020)

70.

Chae, D.W., Kim, B.C.: Characterization on polystyrene/zinc oxide nanocomposites prepared from solution mixing. Polym. Adv. Technol. 16, 846–850 (2005)CrossRef

71.

Li, S., Meng Lin, M., Toprak, M.S., Kim, D.K., Muhammed, M.: Nanocomposites of polymer and inorganic nanoparticles for optical and magnetic applications. Nano. Rev. 1, 5214 (2010)CrossRef

72.

Yuan, W., Wang, F., Chen, Z., Gao, C., Liu, P., Ding, Y., et al.: Efficient grafting of polypropylene onto silica nanoparticles and the properties of PP/PP-g-SiO₂ nanocomposites. Polymer (Guildf) 151, 242–249 (2018)CrossRef

73.

Chen, W.-C., Lin, R.-C., Tseng, S.-M., Kuo, S.-W.: Minimizing the strong screening effect of polyhedral oligomeric silsesquioxane nanoparticles in hydrogen-bonded random copolymers. Polymers (Basel) 10, 303 (2018)CrossRef

74.

Zhang, L., Su, H., Cai, J., Cheng, D., Ma, Y., Zhang, J., et al.: A multifunctional platform for tumor angiogenesis-targeted chemo-thermal therapy using polydopamine-coated gold nanorods. ACS Nano 10, 10404–10417 (2016)CrossRef

75.

Hu, W.-H., Huang, K.-W., Chiou, C.-W., Kuo, S.-W.: Complementary multiple hydrogen bonding interactions induce the self-assembly of supramolecular structures from heteronucleobase-functionalized benzoxazine and polyhedral oligomeric silsesquioxane nanoparticles. Macromolecules 45, 9020–9028 (2012)CrossRef

76.

Wu, Y.-C., Kuo, S.-W.: Self-assembly supramolecular structure through complementary multiple hydrogen bonding of heteronucleobase-multifunctionalized polyhedral oligomeric silsesquioxane (POSS) complexes. J. Mater. Chem. 22, 2982–2991 (2012)CrossRef

77.

Cheng, Y., Zeiger, D.N., Howarter, J.A., Zhang, X., Lin, N.J., Antonucci, J.M., et al.: In-situ formation of silver nanoparticles in photocrosslinking polymers. J. Biomed. Mater. Res. Part B. Appl. Biomater. 97, 124–131 (2011)CrossRef

78.

Shen, X.-J., Yang, S., Shen, J.-X., Ma, J.-L., Wu, Y.-Q., Zeng, X.-L., et al.: Improved mechanical and antibacterial properties of silver-graphene oxide hybrid/polylactid acid composites by in-situ polymerization. Ind. Crops Prod. 130, 571–579 (2019)CrossRef

79.

Mohammad Shafiee, M.R., Sattari, A., Kargar, M., Ghashang, M.: MnO₂/Cr₂O₃/PANI nanocomposites prepared by in-situ oxidation polymerization method: optical and electrical behaviors. J. Appl. Polym. Sci. 136, 47219 (2019)CrossRef

80.

Liu, C., Zhang, L., Liu, H., Cheng, K.: Delivery strategies of the CRISPR-Cas9 gene-editing system for therapeutic applications. J. Control Release 266, 17–26 (2017)CrossRef

81.

Ramesan, M.T., Anjitha, T., Parvathi, K., Anilkumar, T., Mathew, G.: Nano zinc ferrite filler incorporated polyindole/poly (vinyl alcohol) blend: Preparation, characterization, and investigation of electrical properties. Adv. Polym. Technol. 37, 3639–3649 (2018)CrossRef

82.

Thakor, A.S., Gambhir, S.S.: Nanooncology: The future of cancer diagnosis and therapy. CA Cancer J. Clin. (2013). https://doi.org/10.3322/caac.21199CrossRef

83.

Padmanabhan, P., Kumar, A., Kumar, S., Chaudhary, R.K., Gulyás, B.: Nanoparticles in practice for molecular-imaging applications: an overview. Acta Biomater. (2016). https://doi.org/10.1016/j.actbio.2016.06.003CrossRef

84.

Pang, L., Zhang, C., Qin, J., Han, L., Li, R., Hong, C., et al.: A novel strategy to achieve effective drug delivery: exploit cells as carrier combined with nanoparticles. Drug Deliv. (2017). https://doi.org/10.1080/10717544.2016.1230903CrossRef

85.

Bulbake, U., Doppalapudi, S., Kommineni, N., Khan, W.: Liposomal formulations in clinical use: an updated review. Pharmaceutics (2017). https://doi.org/10.3390/pharmaceutics9020012CrossRef

86.

Baeza, A., Colilla, M., Vallet-Regí, M.: Advances in mesoporous silica nanoparticles for targeted stimuli-responsive drug delivery. Expert Opin. Drug Deliv. (2015). https://doi.org/10.1517/17425247.2014.953051CrossRef

87.

Doughty, A.C.V., Hoover, A.R., Layton, E., Murray, C.K., Howard, E.W., Chen, W.R.: Nanomaterial applications in photothermal therapy for cancer. Materials (Basel) (2019). https://doi.org/10.3390/ma12050779CrossRef

88.

Levchenko, I., Bazaka, K., Keidar, M., Xu, S., Fang, J.: Hierarchical multicomponent inorganic metamaterials: intrinsically driven self-assembly at the nanoscale. Adv. Mater. (2018). https://doi.org/10.1002/adma.201702226CrossRef

89.

Silva, C.O., Pinho, J.O., Lopes, J.M., Almeida, A.J., Gaspar, M.M., Reis, C.: Current trends in cancer nanotheranostics: metallic, polymeric, and lipid-based systems. Pharmaceutics (2019). https://doi.org/10.3390/pharmaceutics11010022CrossRef

90.

Murugan, C., Sharma, V., Murugan, R.K., Malaimegu, G., Sundaramurthy, A.: Two-dimensional cancer theranostic nanomaterials: synthesis, surface functionalization and applications in photothermal therapy. J. Control Release (2019). https://doi.org/10.1016/j.jconrel.2019.02.015CrossRef

91.

Tan, Y.Y., Yap, P.K., Xin Lim, G.L., Mehta, M., Chan, Y., Ng, S.W., et al.: Perspectives and advancements in the design of nanomaterials for targeted cancer theranostics. Chem. Biol. Interact. (2020). https://doi.org/10.1016/j.cbi.2020.109221CrossRef

92.

Bejarano, J., Navarro-Marquez, M., Morales-Zavala, F., Morales, J.O., Garcia-Carvajal, I., Araya-Fuentes, E., et al.: Nanoparticles for diagnosis and therapy of atherosclerosis and myocardial infarction: evolution toward prospective theranostic approaches. Theranostics (2018). https://doi.org/10.7150/thno.26284CrossRef

93.

Ali, E.S., Sharker, S.M., Islam, M.T., Khan, I.N., Shaw, S., Rahman, M.A., et al.: Targeting cancer cells with nanotherapeutics and nanodiagnostics: current status and future perspectives. Semin. Cancer Biol. (2020). https://doi.org/10.1016/j.semcancer.2020.01.011CrossRef

94.

Li, Z., Ye, E., David, L.R., Loh, X.J.: Recent advances of using hybrid nanocarriers in remotely controlled therapeutic delivery. Small (2016). https://doi.org/10.1002/smll.201601129

95.

Das, S.S., Bharadwaj, P., Bilal, M., Barani, M., Rahdar, A., Taboada, P., et al.: Stimuli-responsive polymeric nanocarriers for drug delivery, imaging, and theragnosis. Polymers (Basel) (2020). https://doi.org/10.3390/polym12061397CrossRef

96.

Kim, H.S., Lee, D.Y.: Photothermal therapy with gold nanoparticles as an anticancer medication. J. Pharm. Investig. (2017). https://doi.org/10.1007/s40005-016-0292-6CrossRef

97.

Poon, W., Zhang, Y.N., Ouyang, B., Kingston, B.R., Wu, J.L.Y., Wilhelm, S., et al.: Elimination pathways of nanoparticles. ACS Nano (2019). https://doi.org/10.1021/acsnano.9b01383CrossRef

98.

Wu, J.L., Wang, C.Q., Zhuo, R.X., Cheng, S.X.: Multi-drug delivery system based on alginate/calcium carbonate hybrid nanoparticles for combination chemotherapy. Colloids Surfaces B Biointerfaces (2014). https://doi.org/10.1016/j.colsurfb.2014.09.047CrossRef

99.

Nakamura, Y., Mochida, A., Choyke, P.L., Kobayashi, H.: Nanodrug delivery: is the enhanced permeability and retention effect sufficient for curing cancer? Bioconjug. Chem. (2016). https://doi.org/10.1021/acs.bioconjchem.6b00437CrossRef

100.

Zhang, Z., Tongchusak, S., Mizukami, Y., Kang, Y.J., Ioji, T., Touma, M., et al.: Induction of anti-tumor cytotoxic T cell responses through PLGA-nanoparticle mediated antigen delivery. Biomaterials (2011). https://doi.org/10.1016/j.biomaterials.2011.01.067CrossRef

101.

Ge, J., Lei, J., Zare, R.N.: Bovine serum albumin—poly(methyl methacrylate) nanoparticles: an example of frustrated phase separation. Nano Lett. (2011). https://doi.org/10.1021/nl201303qCrossRef

102.

Kang, S., Ahn, S., Lee, J., Kim, J.Y., Choi, M., Gujrati, V., et al.: Effects of gold nanoparticle-based vaccine size on lymph node delivery and cytotoxic T-lymphocyte responses. J. Control Release (2017). https://doi.org/10.1016/j.jconrel.2017.04.024CrossRef

103.

Zhang, L., Wu, S., Qin, Y., Fan, F., Zhang, Z., Huang, C., et al.: Targeted codelivery of an antigen and dual agonists by hybrid nanoparticles for enhanced cancer immunotherapy. Nano. Lett. (2019). https://doi.org/10.1021/acs.nanolett.9b00030CrossRef

104.

Huh, Y.M., Lee, E.S., Lee, J.H., Jun, Y.W., Kim, P.H., Yun, C.O., et al.: Hybrid nanoparticles for magnetic resonance imaging of target-specific viral gene delivery. Adv. Mater. (2007). https://doi.org/10.1002/adma.200701952CrossRef

105.

You, Y.H., Lin, Y.F., Nirosha, B., Chang, H.T., Huang, Y.F.: Polydopamine-coated gold nanostar for combined antitumor and antiangiogenic therapy in multidrug-resistant breast cancer. Nanotheranostics (2019). https://doi.org/10.7150/ntno.36842CrossRef

106.

Wu, F., Liu, Y., Wu, Y., Song, D., Qian, J., Zhu, B.: Chlorin e6 and polydopamine modified gold nanoflowers for combined photothermal and photodynamic therapy. J. Mater. Chem. B (2020). https://doi.org/10.1039/c9tb02646kCrossRef

107.

Schweiger, C., Pietzonka, C., Heverhagen, J., Kissel, T.: Novel magnetic iron oxide nanoparticles coated with poly(ethylene imine)-g-poly(ethylene glycol) for potential biomedical application: synthesis, stability, cytotoxicity and MR imaging. Int. J. Pharm. (2011). https://doi.org/10.1016/j.ijpharm.2010.12.046CrossRef

108.

Park, W., Cho, S., Han, J., Shin, H., Na, K., Lee, B., et al.: Advanced smart-photosensitizers for more effective cancer treatment. Biomater. Sci. (2018). https://doi.org/10.1039/c7bm00872dCrossRef

109.

Wang, M., Chen, Z., Zheng, W., Zhu, H., Lu, S., Ma, E., et al.: Lanthanide-doped upconversion nanoparticles electrostatically coupled with photosensitizers for near-infrared-triggered photodynamic therapy. Nanoscale (2014). https://doi.org/10.1039/c4nr01826eCrossRef

110.

Morgan, N.Y., Kramer-Marek, G., Smith, P.D., Camphausen, K., Capala, J.: Nanoscintillator conjugates as photodynamic therapy-based radiosensitizers: Calculation of required physical parameters. Radiat. Res. (2009). https://doi.org/10.1667/RR1470.1CrossRef

111.

Kamkaew, A., Chen, F., Zhan, Y., Majewski, R.L., Cai, W.: Scintillating nanoparticles as energy mediators for enhanced photodynamic therapy. ACS Nano (2016). https://doi.org/10.1021/acsnano.6b01401CrossRef

112.

Bos, A.J.J.: Thermoluminescence as a research tool to investigate luminescence mechanisms. Materials (Basel) (2017). https://doi.org/10.3390/ma10121357CrossRef

113.

Jing, X., Yang, F., Shao, C., Wei, K., Xie, M., Shen, H., et al.: Role of hypoxia in cancer therapy by regulating the tumor microenvironment. Mol. Cancer (2019). https://doi.org/10.1186/s12943-019-1089-9CrossRef

114.

Senthebane, D.A., Rowe, A., Thomford, N.E., Shipanga, H., Munro, D., Al Mazeedi, M.A.M., et al.: The role of tumor microenvironment in chemoresistance: to survive, keep your enemies closer. Int. J. Mol. Sci. (2017). https://doi.org/10.3390/ijms18071586CrossRef

115.

Yang, G., Tian, J., Chen, C., Jiang, D., Xue, Y., Wang, C., et al.: An oxygen self-sufficient NIR-responsive nanosystem for enhanced PDT and chemotherapy against hypoxic tumors. Chem. Sci. (2019). https://doi.org/10.1039/c9sc00985jCrossRef

116.

Lin, T., Zhao, X., Zhao, S., Yu, H., Cao, W., Chen, W., et al.: O₂-generating MnO₂ nanoparticles for enhanced photodynamic therapy of bladder cancer by ameliorating hypoxia. Theranostics (2018). https://doi.org/10.7150/thno.22465CrossRef

117.

Jha, S., Sharma, P.K., Malviya, R.: Hyperthermia: role and risk factor for cancer treatment. Achiev. Life Sci. (2016). https://doi.org/10.1016/j.als.2016.11.004CrossRef

118.

Wang, H., Li, X., Tse, B.W.C., Yang, H., Thorling, C.A., Liu, Y., et al.: Indocyanine green-incorporating nanoparticles for cancer theranostics. Theranostics (2018). https://doi.org/10.7150/thno.22872CrossRef

119.

Mout, R., Ray, M., Yesilbag Tonga, G., Lee, Y.W., Tay, T., Sasaki, K., et al.: Direct cytosolic delivery of CRISPR/Cas9-ribonucleoprotein for efficient gene editing. ACS Nano (2017). https://doi.org/10.1021/acsnano.6b07600CrossRef

120.

Zhao, Y., Liu, W., Tian, Y., Yang, Z., Wang, X., Zhang, Y., et al.: Anti-EGFR peptide-conjugated triangular gold nanoplates for computed tomography/photoacoustic imaging-guided photothermal therapy of non-small cell lung cancer. ACS Appl. Mater. Interfaces (2018). https://doi.org/10.1021/acsami.7b19013CrossRef

121.

Chang, C.W., Van Spreeuwel, A., Zhang, C., Varghese, S.: PEG/clay nanocomposite hydrogel: a mechanically robust tissue engineering scaffold. Soft Matter (2010). https://doi.org/10.1039/c0sm00067aCrossRef

122.

Zhao, L., Tang, M., Weir, M.D., Detamore, M.S., Xu, H.H.K.: Osteogenic media and rhBMP-2-induced differentiation of umbilical cord mesenchymal stem cells encapsulated in alginate microbeads and integrated in an injectable calcium phosphate-chitosan fibrous scaffold. Tissue Eng. Part A (2011). https://doi.org/10.1089/ten.tea.2010.0521CrossRef

123.

Paul, A., Hasan, A., Kindi, H.A., Gaharwar, A.K., Rao, V.T.S., Nikkhah, M., et al.: Injectable graphene oxide/hydrogel-based angiogenic gene delivery system for vasculogenesis and cardiac repair. ACS Nano (2014). https://doi.org/10.1021/nn5020787

124.

Noh, M., Kim, S.H., Kim, J., Lee, J.R., Jeong, G.J., Yoon, J.K., et al.: Graphene oxide reinforced hydrogels for osteogenic differentiation of human adipose-derived stem cells. RSC Adv. (2017). https://doi.org/10.1039/c7ra02410jCrossRef

125.

Liu, X., Miller, A.L., Park, S., Waletzki, B.E., Terzic, A., Yaszemski, M.J., et al.: Covalent crosslinking of graphene oxide and carbon nanotube into hydrogels enhances nerve cell responses. J. Mater. Chem. B (2016). https://doi.org/10.1039/c6tb01722cCrossRef

126.

Navaei, A., Saini, H., Christenson, W., Sullivan, R.T., Ros, R., Nikkhah, M.: Gold nanorod-incorporated gelatin-based conductive hydrogels for engineering cardiac tissue constructs. Acta Biomater. (2016). https://doi.org/10.1016/j.actbio.2016.05.027CrossRef

127.

Lih, E., Park, W., Park, K.W., Chun, S.Y., Kim, H., Joung, Y.K., et al.: A bioinspired scaffold with anti-inflammatory magnesium hydroxide and decellularized extracellular matrix for renal tissue regeneration. ACS Cent. Sci. (2019). https://doi.org/10.1021/acscentsci.8b00812CrossRef

128.

Duarah, R., Singh, Y.P., Gupta, P., Mandal, B.B., Karak, N.: High performance bio-based hyperbranched polyurethane/carbon dot-silver nanocomposite: a rapid self-expandable stent. Biofabrication (2016). https://doi.org/10.1088/1758-5090/8/4/045013CrossRef

129.

Jeong, D.W., Park, W., Bedair, T.M., Kang, E.Y., Kim, I.H., Park, D.S., et al.: Augmented re-endothelialization and anti-inflammation of coronary drug-eluting stent by abluminal coating with magnesium hydroxide. Biomater. Sci. (2019). https://doi.org/10.1039/c8bm01696hCrossRef

130.

Bassous, N., Cooke, J.P., Webster, T.J.: Enhancing stent effectiveness with nanofeatures. Methodist. Debakey Cardiovasc. J. (2016). https://doi.org/10.14797/mdcj-12-3-163CrossRef

131.

Akturk, O., Kismet, K., Yasti, A.C., Kuru, S., Duymus, M.E., Kaya, F., et al.: Collagen/gold nanoparticle nanocomposites: a potential skin wound healing biomaterial. J. Biomater. Appl. (2016). https://doi.org/10.1177/0885328216644536CrossRef

132.

Tan, A., Farhatnia, Y., Goh, D., Natasha, G., de Mel, A., Lim, J., et al.: Surface modification of a polyhedral oligomeric silsesquioxane poly(carbonate-urea) urethane (POSS-PCU) nanocomposite polymer as a stent coating for enhanced capture of endothelial progenitor cells. Biointerphases (2013). https://doi.org/10.1186/1559-4106-8-23CrossRef

133.

Steinmetz, N.F., Hong, V., Spoerke, E.D., Lu, P., Breitenkamp, K., Finn, M.G., et al.: Buckyballs meet viral nanoparticles: candidates for biomedicine. J. Am. Chem. Soc. (2009). https://doi.org/10.1021/ja902293wCrossRef

134.

Lee, P.W., Hsu, S.H., Tsai, J.S., Chen, F.R., Huang, P.J., Ke, C.J., et al.: Multifunctional core-shell polymeric nanoparticles for transdermal DNA delivery and epidermal Langerhans cells tracking. Biomaterials (2010). https://doi.org/10.1016/j.biomaterials.2009.11.100CrossRef

135.

Ha, Y.J., Lee, S.M., Mun, C.H., Kim, H.J., Bae, Y., Lim, J.H., et al.: Methotrexate-loaded multifunctional nanoparticles with near-infrared irradiation for the treatment of rheumatoid arthritis. Arthritis Res. Ther. (2020). https://doi.org/10.1186/s13075-020-02230-yCrossRef

136.

Askari, A., Tajvar, S., Nikkhah, M., Mohammadi, S., Hosseinkhani, S.: Synthesis, characterization and in-vitro toxicity evaluation of doxorubicin-loaded magnetoliposomes on MCF-7 breast cancer cell line. J. Drug Deliv. Sci. Technol. (2020). https://doi.org/10.1016/j.jddst.2019.101447CrossRef

137.

Xu, C., Wang, B., Sun, S.: Dumbbell-like Au-Fe₃O₄ nanoparticles for target-specific platin delivery. J. Am. Chem. Soc. (2009). https://doi.org/10.1021/ja900790vCrossRef

138.

Gu, H., Zheng, R., Zhang, X.X., Xu, B.: Facile one-pot synthesis of bifunctional heterodimers of nanoparticles: a conjugate of quantum dot and magnetic nanoparticles. J. Am. Chem. Soc. (2004). https://doi.org/10.1021/ja0496423CrossRef

139.

Jiang, J., Gu, H., Shao, H., Devlin, E., Papaefthymiou, G.C., Ying, J.Y.: Bifunctional Fe₃O₄-Ag heterodimer nanoparticles for two-photon fluorescence imaging and magnetic manipulation. Adv. Mater. (2008). https://doi.org/10.1002/adma.200800498CrossRef

140.

Wang, G., Gao, W., Zhang, X., Mei, X.: Au nanocage functionalized with ultra-small Fe₃O₄ nanoparticles for targeting T1–T2 dual MRI and CT imaging of tumor. Sci. Rep. (2016). https://doi.org/10.1038/srep28258CrossRef

141.

Li, C., Chen, T., Ocsoy, I., Zhu, G., Yasun, E., You, M., et al.: Gold-coated Fe₃O₄ nanoroses with five unique functions for cancer cell targeting, imaging, and therapy. Adv. Funct. Mater. (2014). https://doi.org/10.1002/adfm.201301659CrossRef

142.

Ganipineni, L.P., Ucakar, B., Joudiou, N., Bianco, J., Danhier, P., Zhao, M., et al.: Magnetic targeting of paclitaxel-loaded poly(lactic-co-glycolic acid)-based nanoparticles for the treatment of glioblastoma. Int. J. Nanomed. (2018). https://doi.org/10.2147/IJN.S165184CrossRef

143.

Zhang, R.X., Ahmed, T., Li, L.Y., Li, J., Abbasi, A.Z., Wu, X.Y.: Design of nanocarriers for nanoscale drug delivery to enhance cancer treatment using hybrid polymer and lipid building blocks. Nanoscale (2017). https://doi.org/10.1039/c6nr08486aCrossRef

144.

Sailor, M.J., Park, J.H.: Hybrid nanoparticles for detection and treatment of cancer. Adv. Mater. (2012). https://doi.org/10.1002/adma.201200653CrossRef

145.

Ba, H., Rodríguez-Fernández, J., Stefani, F.D., Feldmann, J.: Immobilization of gold nanoparticles on living cell membranes upon controlled lipid binding. Nano. Lett. (2010). https://doi.org/10.1021/nl101454aCrossRef

146.

Paasonen, L., Sipilä, T., Subrizi, A., Laurinmäki, P., Butcher, S.J., Rappolt, M., et al.: Gold-embedded photosensitive liposomes for drug delivery: triggering mechanism and intracellular release. J. Control Release (2010). https://doi.org/10.1016/j.jconrel.2010.07.095CrossRef

147.

Wu, G., Mikhailovsky, A., Khant, H.A., Fu, C., Chiu, W., Zasadzinski, J.A.: Remotely triggered liposome release by near-infrared light absorption via hollow gold nanoshells. J. Am. Chem. Soc. (2008). https://doi.org/10.1021/ja802656dCrossRef

148.

Liu, T.Y., Huang, T.C.: A novel drug vehicle capable of ultrasound-triggered release with MRI functions. Acta Biomater. (2011). https://doi.org/10.1016/j.actbio.2011.06.038CrossRef

149.

Chen, Y., Bose, A., Bothun, G.D.: Controlled release from bilayer-decorated magnetoliposomes via electromagnetic heating. ACS Nano (2010). https://doi.org/10.1021/nn100274vCrossRef

150.

Mikhaylov, G., Mikac, U., Magaeva, A.A., Itin, V.I., Naiden, E.P., Psakhye, I., et al.: Ferri-liposomes as an MRI-visible drug-delivery system for targeting tumours and their microenvironment. Nat. Nanotechnol. (2011). https://doi.org/10.1038/nnano.2011.112CrossRef

151.

Al-Jamal, W.T., Al-Jamal, K.T., Tian, B., Lacerda, L., Bomans, P.H., Frederik, P.M., et al.: Lipid - Quantum dot bilayer vesicles enhance tumor cell uptake and retention in-vitro and in-vivo. ACS Nano (2008). https://doi.org/10.1021/nn700176aCrossRef

152.

Weng, K.C., Noble, C.O., Papahadjopoulos-Sternberg, B., Chen, F.F., Drummond, D.C., Kirpotin, D.B., et al.: Targeted tumor cell internalization and imaging of multifunctional quantum dot-conjugated immunoliposomes in-vitro and in-vivo. Nano. Lett. (2008). https://doi.org/10.1021/nl801488uCrossRef

153.

Li, H., Wang, J., Huang, G., Wang, P., Zheng, R., Zhang, C., et al.: Multifunctionalized microbubbles for cancer diagnosis and therapy. Anticancer Agents Med. Chem. (2013). https://doi.org/10.2174/1871520611313030004CrossRef

154.

Accardo, A., Tesauro, D., Morelli, G.: Peptide-based targeting strategies for simultaneous imaging and therapy with nanovectors. Polym. J. (2013). https://doi.org/10.1038/pj.2012.215CrossRef

155.

Namiki, Y., Namiki, T., Yoshida, H., Ishii, Y., Tsubota, A., Koido, S., et al.: A novel magnetic crystal-lipid nanostructure for magnetically guided in-vivo gene delivery. Nat. Nanotechnol. (2009). https://doi.org/10.1038/nnano.2009.202CrossRef

156.

Wang, W., Cheng, D., Gong, F., Miao, X., Shuai, X.: Design of multifunctional micelle for tumor-targeted intracellular drug release and fluorescent imaging. Adv. Mater. (2012). https://doi.org/10.1002/adma.201104066CrossRef

157.

Park, J.H., Von Maltzahn, G., Ruoslahti, E., Bhatia, S.N., Sailor, M.J.: Micellar hybrid nanoparticles for simultaneous magnetofluorescent imaging and drug delivery. Angew. Chemie. Int. Ed. (2008). https://doi.org/10.1002/anie.200801810CrossRef

158.

Xu, H., Cheng, L., Wang, C., Ma, X., Li, Y., Liu, Z.: Polymer encapsulated upconversion nanoparticle/iron oxide nanocomposites for multimodal imaging and magnetic targeted drug delivery. Biomaterials (2011). https://doi.org/10.1016/j.biomaterials.2011.08.053CrossRef

159.

Vieweger, M., Goicochea, N., Koh, E.S., Dragnea, B.: Photothermal imaging and measurement of protein shell stoichiometry of single HIV-1 Gag virus-like nanoparticles. ACS Nano (2011). https://doi.org/10.1021/nn202184xCrossRef

160.

Lee, S.M., Kim, H.J., Ha, Y.J., Park, Y.N., Lee, S.K., Park, Y.B., et al.: Targeted chemo-photothermal treatments of rheumatoid arthritis using gold half-shell multifunctional nanoparticles. ACS Nano (2013). https://doi.org/10.1021/nn301215qCrossRef

161.

Cho, H.S., Dong, Z., Pauletti, G.M., Zhang, J., Xu, H., Gu, H., et al.: Fluorescent, superparamagnetic nanospheres for drug storage, targeting, and imaging: A multifunctional nanocarrier system for cancer diagnosis and treatment. ACS Nano (2010). https://doi.org/10.1021/nn101000eCrossRef

162.

Wang, C., Chen, J., Talavage, T., Irudayaraj, J.: Gold Nanorod/Fe3O4 nanoparticle “nano-pearl- necklaces” for simultaneous targeting, dual-mode imaging, and photothermal ablation of cancer cells. Angew. Chemie. Int. Ed. (2009). https://doi.org/10.1002/anie.200805282CrossRef

163.

Bhirde, A.A., Patel, V., Gavard, J., Zhang, G., Sousa, A.A., Masedunskas, A., et al.: Targeted killing of cancer cells in-vivo and in-vitro with EGF-directed carbon nanotube-based drug delivery. ACS Nano (2009). https://doi.org/10.1021/nn800551sCrossRef

164.

Bertrand, N., Wu, J., Xu, X., Kamaly, N., Farokhzad, O.C.: Cancer nanotechnology: the impact of passive and active targeting in the era of modern cancer biology. Adv. Drug Deliv. Rev. (2014). https://doi.org/10.1016/j.addr.2013.11.009CrossRef

Title: Hybrid Nanostructures for Biomedical Applications
Authors: R. Rajakumari
Abhimanyu Tharayil
Sabu Thomas
Nandakumar Kalarikkal
Publisher: Springer International Publishing
Book: Hybrid Phosphor Materials
Print ISBN: 978-3-030-90505-7

Electronic ISBN: 978-3-030-90506-4

Copyright Year: 2022
DOI: https://doi.org/10.1007/978-3-030-90506-4_12

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