Innovative, long-lasting and eco-friendly surface decontamination approach using modified Titania based on nanotechnology

Hospital-acquired infections (HAI), usually known as nosocomial infections, have become a major challenge and they are frequently associated with resistance to the highest priority critically important antimicrobials. In this line, the treatment of each infection can be compromised. The solid surfaces of the hospital become significant sources of transmission and lead most often to the contamination and cross-contamination of nosocomial pathogens to the patients and staff. Traditional biocides (i.e. detergent, alcohol, chloride-based and antibiotics) have limited effectiveness over time. As alternative to this sanitization approach, modified Nano TiO₂ coating, was selected for this preliminary study. After applying the coat on a solid surface, it will become change to a transparent antimicrobial film. When light fall on coated particles, they generate electron–hole pairs. These generated pairs will react with moisture and oxygen from the air which generates reactive radicals with capacity to attack microbial cells and promote their death. From in vitro study, the coating is inhibiting three types of bacteria (E. coli, S. aureus, P. aeruginosa) by growing and colonizing on the solid surfaces. Nanoparticle acts constantly and is durable over time due to the activity as photocatalyst which can reduce and contain the proliferation of microorganisms. In such a scenario, Ecobactix comes as a safe and long-lasting antibacterial shield for surfaces. Modified TiO₂ coating based on photocatalysis (nano Titania) is a promising, long-lasting and effective biocidal technique for disinfection surfaces, especially innovative product around the nosocomial environment.