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International Journal of Computer Assisted Radiology and Surgery OnlineFirst articles

16-08-2019 | Original Article

Force classification during robotic interventions through simulation-trained neural networks

Intravitreal injections are among the most common surgical interventions in ophthalmology with more than 4 million injections worldwide in 2014 alone [ 1 ]. This procedure is principally used in the treatment of diabetic maculopathy and for …

Andrea Mendizabal, Raphael Sznitman, Stephane Cotin

12-08-2019 | Original Article

GPU-based 3D iceball modeling for fast cryoablation simulation and planning

The treatment of abdominal tumors has undergone significant improvements with the introduction of percutaneous procedures based on thermal ablation. The advantages of these minimally invasive procedures are that they lead to faster patient …

Ehsan Golkar, Pramod P. Rao, Leo Joskowicz, Afshin Gangi, Caroline Essert

11-08-2019 | Original Article Open Access

FAConstructor: an interactive tool for geometric modeling of nerve fiber architectures in the brain

Fig. 1 Fiber orientation maps of a coronal section through the human brain obtained with 3D-PLI. The determined nerve fiber orientations are color-coded as indicated by the color sphere on the top left. a Whole brain section with long- and …

Jan André Reuter, Felix Matuschke, Miriam Menzel, Nicole Schubert, Kévin Ginsburger, Cyril Poupon, Katrin Amunts, Markus Axer

10-08-2019 | Original Article

Detection and segmentation of lymphomas in 3D PET images via clustering with entropy-based optimization strategy

Lymphoma is a cancer of the lymphatic system characterized by lymphocyte proliferation. There are 2 kinds of lymphomas: Hodgkin disease and non-Hodgkin lymphoma (NHL), and diffuse large B-cell lymphoma (DLBCL) is the most frequent non-Hodgkin …

Haigen Hu, Pierre Decazes, Pierre Vera, Hua Li, Su Ruan

07-08-2019 | Original Article

Computer-assisted intra-operative verification of surgical outcome for the treatment of syndesmotic injuries through contralateral side comparison

Fig. 1 Proposed workflow …

Sarina Thomas, Fabian Isensee, Simon Kohl, Maxim Privalov, Nils Beisemann, Benedict Swartman, Holger Keil, Sven Y. Vetter, Jochen Franke, Paul A. Grützner, Lena Maier-Hein, Marco Nolden, Klaus Maier-Hein

07-08-2019 | Original Article Open Access

Segmentation-based registration of ultrasound volumes for glioma resection in image-guided neurosurgery

In brain surgery for tumor removal, neurosurgeons usually plan the intervention on pre-surgical images. The most widely used modality for neurosurgery planning is magnetic resonance imaging [ 1 , 2 , 3 ]. To help physicians with the resection …

Luca Canalini, Jan Klein, Dorothea Miller, Ron Kikinis

07-08-2019 | Original Article

Improving realism in patient-specific abdominal ultrasound simulation using CycleGANs

Ultrasound (US) is a frequently used medical imaging technique that is extensively applied as an examination tool for diagnosis, treatment and in emergentology [ 17 ]. Compared to other modalities such as X-ray or computed tomography (CT), US …

Santiago Vitale, José Ignacio Orlando, Emmanuel Iarussi, Ignacio Larrabide

06-08-2019 | Original Article

Fusing information from multiple 2D depth cameras for 3D human pose estimation in the operating room

Robust human pose estimation is a key component for many of today’s and future computer vision tasks. Areas of usage range from surveillance systems to entertainment solutions to autonomous driving. Likewise, precise knowledge of 3D joint …

Lasse Hansen, Marlin Siebert, Jasper Diesel, Mattias P. Heinrich

05-08-2019 | Original Article

Synthesis of CT images from digital body phantoms using CycleGAN

Tom Russ, Stephan Goerttler, Alena-Kathrin Schnurr, Dominik F. Bauer, Sepideh Hatamikia, Lothar R. Schad, Frank G. Zöllner, Khanlian Chung

03-08-2019 | Original Article

Pitfalls in interventional X-ray organ dose assessment—combined experimental and computational phantom study: application to prostatic artery embolization

Over the last decades, the number of fluoroscopically guided interventions (FGI) increased considerably, putting a stronger focus on radiation protection, management, and safety for both patients and radiologists. In contrast to diagnostic …

Philipp Roser, Annette Birkhold, Xia Zhong, Philipp Ochs, Elizaveta Stepina, Markus Kowarschik, Rebecca Fahrig, Andreas Maier

31-07-2019 | Review Article

Deep learning-based digital subtraction angiography image generation

Clinical digital subtraction angiography (DSA) plays an important role in diagnosing cardiovascular disease [ 1 ], such as cerebral thrombosis, coronary heart disease and vasculitis. The DSA images are subtracted from the mask image and live images …

Yufeng Gao, Yu Song, Xiangrui Yin, Weiwen Wu, Lu Zhang, Yang Chen, Wanyin Shi

30-07-2019 | Original Article

Flow-splitting-based computation of outlet boundary conditions for improved cerebrovascular simulation in multiple intracranial aneurysms

Fig. 1 Illustration of complex vascular domains represented by 3D surface models with eight intracranial aneurysms from two patients. The first case exhibits four aneurysms (A1–A4) at a single vessel tree with twelve vessel outlets. The second case …

Sylvia Saalfeld, Samuel Voß, Oliver Beuing, Bernhard Preim, Philipp Berg

30-07-2019 | Original Article

Accurate and interpretable evaluation of surgical skills from kinematic data using fully convolutional neural networks

Over the last century, the standard training exercise of Dr. William Halsted has dominated surgical education in various regions of the world [ 18 ]. His training methodology of “see one, do one, teach one” is still one of the most adopted …

Hassan Ismail Fawaz, Germain Forestier, Jonathan Weber, Lhassane Idoumghar, Pierre-Alain Muller

29-07-2019 | Original Article

Prediction outcomes for anterior vertebral body growth modulation surgery from discriminant spatiotemporal manifolds

Anterior vertebral body growth modulation (AVBGM) is a corrective spine surgery, connecting a segment of vertebrae together by a flexible polypropylene cable applied to the spine anteriorly. This fusion-less technique applies compressive forces on …

William Mandel, Olivier Turcot, Dejan Knez, Stefan Parent, Samuel Kadoury

27-07-2019 | Original Article Open Access

Novel automated vessel pattern characterization of larynx contact endoscopic video images

The larynx (voice box) is part of the head and neck region, and laryngeal cancer belongs to the most common cancer types with high incidence and mortality. Precancerous lesions such as laryngeal dysplasia precede the development of laryngeal …

Nazila Esmaeili, Alfredo Illanes, Axel Boese, Nikolaos Davaris, Christoph Arens, Michael Friebe

26-07-2019 | Original Article

Fully automated intracranial ventricle segmentation on CT with 2D regional convolutional neural network to estimate ventricular volume

Hydrocephalus, or pathologic enlargement of the intracranial ventricles, is one cause of elevated intracranial pressure which can have devastating consequences. Due to the unchanging volume of the cranial vault, relatively small increases in …

Trevor J. Huff, Parker E. Ludwig, David Salazar, Justin A. Cramer

26-07-2019 | Original Article

Co-localized augmented human and X-ray observers in collaborative surgical ecosystem

In modern orthopedic surgery, there is a growing interest toward employing minimally invasive and percutaneous approaches [ 1 , 2 ]. In fracture repair, percutaneous treatments yield fewer complications, reduced blood loss and damage to soft tissue …

Javad Fotouhi, Mathias Unberath, Tianyu Song, Jonas Hajek, Sing Chun Lee, Bastian Bier, Andreas Maier, Greg Osgood, Mehran Armand, Nassir Navab

23-07-2019 | Original Article

Robust GPU-based virtual reality simulation of radio-frequency ablations for various needle geometries and locations

In liver cancer therapy besides the conservatively used open laparotomy [ 9 , 30 ], there are several options for the treatment of primary liver tumors.

Niclas Kath, Heinz Handels, Andre Mastmeyer

18-07-2019 | Original Article

Radiation-free methods for navigated screw placement in slipped capital femoral epiphysis surgery

Currently, many clinical procedures employ computer-assisted surgery (CAS) methods to improve the performance and precision of the entire surgical process including pre-planning, execution and postoperative verification. Orthopedic surgery is a …

Bamshad Azizi Koutenaei, Javad Fotouhi, Farshid Alambeigi, Emmanuel Wilson, Ozgur Guler, Mathew Oetgen, Kevin Cleary, Nassir Navab

17-07-2019 | Original Article

A “eye-in-body” integrated surgery robot system for stereotactic surgery

Robot-assisted stereotactic surgery is increasingly being valued clinically for its accuracy and stability [ 1 , 2 ]. In stereotactic surgery, the patient’s anatomy and surgical plan can vary, the patient may shift and move, and the robotic arm may …

Liang Li, Julia Wu, Hui Ding, Guangzhi Wang