2015 | OriginalPaper | Chapter
Magnetic Resonance Current Density Imaging: Applications to Electrochemotherapy and Irreversible Electroporation
Authors : Igor Serša, Franci Bajd, Matej Kranjc, Oh In Kwon, Hyung Joong Kim, Tong In Oh, Eung Je Woo, Damijan Miklavčič
Published in: 6th European Conference of the International Federation for Medical and Biological Engineering
Publisher: Springer International Publishing
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Electrochemotherapy (ECT) and Irreversible Electroporation (IRE) are two advanced methods in medical treatment that both critically depend on the magnitude and duration of the applied electric field over the targeted tissue (tumor or other tissue abnormality). Therefore a method that would enable a reliable monitoring of the electric field during application of ECT or IRE electric pulses is of a high priority. Recent advances in magnetic resonance imaging (MRI) and electrical impedance tomography (EIT) indicate that a combination of the two methods is a good candidate for the task. In this study, theory and results on a model system demonstrate current capability of MRI and EIT for monitoring ECT and IRE treatment.