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High Order Whitney Forms on Simplices and the Question of Potentials Read chapter Read first chapter

2021 | OriginalPaper | Chapter

Mathematical Assessment of the Role of Three Factors Entangled in the Development of Glaucoma by Means of the Ocular Mathematical Virtual Simulator

Authors : Lorenzo Sala, Christophe Prud’homme, Giovanna Guidoboni, Marcela Szopos, Alon Harris

Published in: Numerical Mathematics and Advanced Applications ENUMATH 2019

Publisher: Springer International Publishing

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Abstract

Glaucoma is a multifactorial neurodegenerative disease that involves the optic nerve head and the death of the retinal ganglion cells. The main challenge in medicine is to understand the origin of this degeneration. In this paper we present a virtual clinical study employing the Ocular Mathematical Virtual Simulator (OMVS), a mathematical model, which is able to disentangle the hidden mechanisms and to investigate the causes of this ocular neurodegeneration. In particular, we focus our attention on the influence that intraocular pressure, intracranial pressure and arterial blood pressure set on the ocular hemodynamics.

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previous chapter Reduced Order Methods for Parametrized Non-linear and Time Dependent Optimal Flow Control Problems, Towards Applications in Biomedical and Environmental Sciences
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Metadata
Title
Mathematical Assessment of the Role of Three Factors Entangled in the Development of Glaucoma by Means of the Ocular Mathematical Virtual Simulator
Authors
Lorenzo Sala
Christophe Prud’homme
Giovanna Guidoboni
Marcela Szopos
Alon Harris
Copyright Year
2021
Book
Numerical Mathematics and Advanced Applications ENUMATH 2019

Print ISBN: 978-3-030-55873-4

Electronic ISBN: 978-3-030-55874-1

Copyright Year: 2021

DOI
https://doi.org/10.1007/978-3-030-55874-1_84

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