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Adaptive Filter Removes Variability Caused by Respiration from Impedance Cardiography Signal Read chapter Read first chapter

2020 | OriginalPaper | Chapter

Microneedle-Based Sensor Systems for Real-Time Continuous Transdermal Monitoring of Analytes in Body Fluids

Authors : Edina Vranić, Amina Tucak, Merima Sirbubalo, Ognjenka Rahić, Alisa Elezović, Jasmina Hadžiabdić

Published in: CMBEBIH 2019

Publisher: Springer International Publishing

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Abstract

Microneedles, tiny micron-sized structures, made of a variety of materials, have been recently developed for a painless and safe transdermal delivery of drugs through the skin. While microneedles minimally disrupt the outermost layer of the skin and create a pathway to deliver the therapeutic agents, they could also act as conduits for biosignal sensing. Microneedle-based sensors made of conductive and electrochemically reactive biomaterials can provide the valuable information on the levels of analytes in the blood. Also, researchers have realized the great potential of microneedles integrated with microelectrodes for extraction of interstitial fluid and capillary blood, for enhanced monitoring of patient health. Furthermore, they could serve as a tool for analysis of complex medical conditions and illnesses. This microneedle sensor technology can provide a sophisticated analytical approach for in situ and simultaneous detection of numerous analytes. The microneedles can also be used to measure metabolites, biomarkers, and drug level in the interstitial fluid and capillary blood, as well as for the use of microneedle array technology as biosensors for continuous monitoring of analytes in body fluids.

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Metadata
Title
Microneedle-Based Sensor Systems for Real-Time Continuous Transdermal Monitoring of Analytes in Body Fluids
Authors
Edina Vranić
Amina Tucak
Merima Sirbubalo
Ognjenka Rahić
Alisa Elezović
Jasmina Hadžiabdić
Copyright Year
2020
Book
CMBEBIH 2019

Print ISBN: 978-3-030-17970-0

Electronic ISBN: 978-3-030-17971-7

Copyright Year: 2020

DOI
https://doi.org/10.1007/978-3-030-17971-7_26