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1987 | OriginalPaper | Chapter

Miotic Effect of Echothiophate Iodide in Humans: Possible Role of Iris Substance P

Authors : M. Fanciullacci, M. Nicolodi, U. Pietrini, P. Geppetti, S. Rizzo, F. Sicuteri

Published in: Substance P and Neurokinins

Publisher: Springer New York

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In man trigeminal stimulation produces constriction of the pupil: this pupillary effect can be attributed to substance P (SP) release from trigeminal sensory nerve fibers [1]. In fact SP-1ike immunoreactive nerve fibers have been visualized in iris sphincter muscle [2]. This discovery has opened question about the pathophysiological role of SP in the human iris. Our radioimmunological and pupillopharmacological data have been carried out to clarify this problem.

Metadata
Title
Miotic Effect of Echothiophate Iodide in Humans: Possible Role of Iris Substance P
Authors
M. Fanciullacci
M. Nicolodi
U. Pietrini
P. Geppetti
S. Rizzo
F. Sicuteri
Copyright Year
1987
Publisher
Springer New York
DOI
https://doi.org/10.1007/978-1-4612-4672-5_92