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2019 | OriginalPaper | Chapter

Model-Based Analysis of Spinal Cord Stimulation for Chronic Pain

Authors : Scott F. Lempka, Hans Zander, Carlos J. Anaya, Alexandria Wyant, John G. Ozinga IV, Andre G. Machado

Published in: Converging Clinical and Engineering Research on Neurorehabilitation III

Publisher: Springer International Publishing

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Abstract

Spinal cord stimulation (SCS) is a widely-used therapy for chronic pain management. Computational models provide a valuable tool to study the effects of SCS on the nervous system. However, it is critical that these models include sufficient detail to correlate model predictions with clinical effects, including patient-specific data. Therefore, in this study, we developed a patient-specific computer model for a patient undergoing SCS to treat neuropathic pain. The patient-specific model predicted sensory threshold estimates that were consistent with the corresponding clinical measurements. These results demonstrate the potential for patient-specific computer models to quantitatively describe the axonal response to SCS and to address scientific questions related to clinical SCS.

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Metadata
Title
Model-Based Analysis of Spinal Cord Stimulation for Chronic Pain
Authors
Scott F. Lempka
Hans Zander
Carlos J. Anaya
Alexandria Wyant
John G. Ozinga IV
Andre G. Machado
Copyright Year
2019
DOI
https://doi.org/10.1007/978-3-030-01845-0_8