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Published in:
Introduction to Nanomedicine Read chapter Read first chapter

2016 | OriginalPaper | Chapter

5. Modeling Nanoparticle Optics

Authors : Renat R. Letfullin, Thomas F. George

Published in: Computational Nanomedicine and Nanotechnology

Publisher: Springer International Publishing

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Abstract

As we discussed in the preceding Chap. 4, the optimal range of nanoparticle sizes and optimal wavelength of radiation for effective activating/heating of nanoparticles in tumor cells can be calculated on the basis of the Lorenz–Mie diffraction theory at the single-scattering approximation. The Mie formalism requires the use of two dimensionless input parameters: the complex refractive index of the nanoparticle and the surrounding medium at the given wavelength. In this chapter we introduce a computer software and perform Mie simulations of absorption, scattering, and extinction efficiencies of different types of nanoparticles as a function of particle size and the wavelength of radiation in different surrounding biological media. Also, we calculate and then use the differences in optical properties of normal and cancer cell organelles in order to design new cancer detection and treatment methods.

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previous chapter Introduction to Light–Particle Interactions
next chapter Thermal Interaction of Particle and Radiation
Appendix
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Metadata
Title
Modeling Nanoparticle Optics
Authors
Renat R. Letfullin
Thomas F. George
Copyright Year
2016
Book
Computational Nanomedicine and Nanotechnology

Print ISBN: 978-3-319-43575-6

Electronic ISBN: 978-3-319-43577-0

Copyright Year: 2016

DOI
https://doi.org/10.1007/978-3-319-43577-0_5