Advertisement
Published in:
2016 | OriginalPaper | Chapter
Mutual Entrainment of Cardiac-Oscillators Through Mechanical Interaction
Authors : Koki Maekawa, Naoki Inoue, Masahiro Shimizu, Yoshihiro Isobe, Taro Saku, Koh Hosoda
Published in: Biomimetic and Biohybrid Systems
Publisher: Springer International Publishing
Activate our intelligent search to find suitable subject content or patents.
Select sections of text to find matching patents with Artificial Intelligence. powered by
Select sections of text to find additional relevant content using AI-assisted search. powered by
Abstract
This paper focus on bio-robots driven by cardiomyocyte-powered actuators. Towards biomaterial-based robotic actuators that exhibit co-operative motion, this study intends to deal with mutual entrainment between two cardiac-oscillators with mechanical interaction. The cardiac-oscillator is an oriented collagen sheet seeded cultured rat cardiomyocytes. Mechanically coupled cardiac-oscillator sysytem was developed consisting of two cardiac-oscillators connected mechanically via a PDMS film. Mechanically coupled cardiac-oscillator system and a single cardiac-oscillator was applied electric stimulation for investigating the function of mechanical structure. As a result of experiment, we observed mutual entrainment occurred in only mechanically coupled structure.