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Published in: Cellulose 12/2021

08-07-2021 | Review Paper

Nanocellulose based hydrogel or aerogel scaffolds for tissue engineering

Authors: Zhenke Wei, Chaojun Wu, Ronggang Li, Dongmei Yu, Qijun Ding

Published in: Cellulose | Issue 12/2021

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Abstract

Some structures and properties of hydrogel or aerogel tissue engineering scaffolds can be regulated by adding nanocellulose due to its biocompatibility, biodegradability, hydrophilic and excellent mechanical properties. In this review, we briefly introduce the category, characteristics and preparation methods of nanocellulose. Then we cover the most recent work on nanocellulose based hydrogel or aerogel scaffolds, and present an in-depth discussion of the roles of nanocellulose in skin, bone, vessel, cartilage, soft tissue, muscle, heart and tooth hydrogel or aerogel scaffolds. The addition of nanocellulose not only has a great influence on the Young’s modulus, compressive Young’s modulus, swelling rate, gel time, surface morphology, porosity, the antibacterial properties of scaffolds, but also can regulate the balances among these properties in order to promote the proliferation rates of cells and the biorecognition sites of the scaffolds. Finally, some challenges of nanocellulose based scaffolds are also prospected. We anticipate that the review supplies some guides for nanocellulose applied in scaffolds.

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Metadata
Title
Nanocellulose based hydrogel or aerogel scaffolds for tissue engineering
Authors
Zhenke Wei
Chaojun Wu
Ronggang Li
Dongmei Yu
Qijun Ding
Publication date
08-07-2021
Publisher
Springer Netherlands
Published in
Cellulose / Issue 12/2021
Print ISSN: 0969-0239
Electronic ISSN: 1572-882X
DOI
https://doi.org/10.1007/s10570-021-04021-3

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