Top

Published in:

2020 | OriginalPaper | Chapter

Nanomaterials in Nutraceuticals Applications

Authors : Mahendra Singh, Navneeta Singh, Balakumar Chandrasekaran, Pran Kishore Deb

Published in: Integrative Nanomedicine for New Therapies

Publisher: Springer International Publishing

Activate our intelligent search to find suitable subject content or patents.

search-config

AI-assisted search

Off

Abstract

Diverse strategies are adopted to fight against various diseases and probable health risks. Besides the pharmaceutical approach, diet-based strategies are also deemed apt to avert various disorders. “Nutraceuticals” considered as bioactive components found in natural products. Bioactive components are additional nutritional ingredients that typically present in small quantities of foods that are used in day-to-day life and strongly believed to play a crucial role in the maintenance of our health. The food products used as nutraceuticals can be categorized as dietary fiber, prebiotics, probiotics, polyunsaturated fatty acids, antioxidants and other different types of herbal/natural foods. These nutraceuticals facilitate in combating a number of the major health problems including microbial infections. In recent years, nanotechnology-based formulations like micro- and nanoencapsulation have been a rising interest for nutraceutical, food and pharmaceutical applications. To enhance nutritional quality and stability of the nutraceuticals, one option is to encapsulate the functional ingredients using food-grade or “generally recognized as safe” (GRAS) materials that can exhibit controlled-release behavior. These diversity of building blocks and formulation methods led to nanocarriers like nanoemulsion, nanodispersion, nanoparticles, liposomes etc. with diverse physicochemical properties and functional characteristics. Based on the above-mentioned facts, this chapter provides an insight of some of the emerging nanomaterial-based applications being commercialized in nutraceuticals. A glimpse on various research work undertaken for the nanomaterials in the field of nutraceuticals is also discussed in this chapter.

Dont have a licence yet? Then find out more about our products and how to get one now:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

über 102.000 Bücher
über 537 Zeitschriften

aus folgenden Fachgebieten:

Automobil + Motoren
Bauwesen + Immobilien
Business IT + Informatik
Elektrotechnik + Elektronik
Energie + Nachhaltigkeit
Finance + Banking
Management + Führung
Marketing + Vertrieb
Maschinenbau + Werkstoffe
Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

inform now

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

über 67.000 Bücher
über 390 Zeitschriften

aus folgenden Fachgebieten:

Automobil + Motoren
Bauwesen + Immobilien
Business IT + Informatik
Elektrotechnik + Elektronik
Energie + Nachhaltigkeit
Maschinenbau + Werkstoffe

Jetzt Wissensvorsprung sichern!

inform now

previous chapter Nanomedicines in Tuberculosis: Diagnosis, Therapy and Nanodrug Delivery

next chapter Correction to: Integrative Nanomedicine for New Therapies

Aboalnaja, K. O., Yaghmoor, S., Kumosani, T. A., & McClements, D. J. (2016). Utilization of nanoemulsions to enhance bioactivity of pharmaceuticals, supplements, and nutraceuticals: Nanoemulsion delivery systems and nanoemulsion excipient systems. Expert opinion on drug delivery, 13(9), 1327–1336.CrossRef

Aditya, N. P., Chimote, G., Gunalan, K., Banerjee, R., Patankar, S., & Madhusudhan, B. (2012). Curcuminoids-loaded liposomes in combination with arteether protects against Plasmodium berghei infection in mice. Experimental Parasitology, 131(3), 292–299.CrossRef

Akhlaghi, S. P., Berry, R. M., & Tam, K. C. (2015). Modified cellulose nanocrystal for vitamin C delivery. An Official Journal of the American Association of Pharmaceutical Scientists, 16(2), 306–314.

Alaarg, A., Jordan, N. Y., Verhoef, J. J., Metselaar, J. M., Storm, G., & Kok, R. J. (2016). Docosahexaenoic acid liposomes for targeting chronic inflammatory diseases and cancer: An in vitro assessment. International Journal of Nanomedicine, 11, 5027.CrossRef

Alexander, M., Lopez, A. A., Fang, Y., & Corredig, M. (2012). Incorporation of phytosterols in soy phospholipids nanoliposomes: Encapsulation efficiency and stability. LWT-Food Science and Technology, 47(2), 427–436.CrossRef

Annunziata, G., Tenore, G. C., & Novellino, E. (2018). Resveratrol-based nutraceuticals for the management of diabetes and obesity: Real therapeutic potential or a mere palliative. Archives of Diabetes & Obesity, 1–2.

Aparna, C., Prathima, S., & Patnaik, R. (2015). Enhanced transdermal permeability of telmisartan by a novel nanoemulsion gel. International Journal of Pharmacy and Pharmaceutical Sciences, 7, 335–342.

Augustin, M. A., & Hemar, Y. (2009). Nano-and micro-structured assemblies for encapsulation of food ingredients. Chemical Society Reviews, 38(4), 902–912.CrossRef

Bochicchio, S., Barba, A. A., Grassi, G., & Lamberti, G. (2016). Vitamin delivery: Carriers based on nanoliposomes produced via ultrasonic irradiation. LWT-Food Science and Technology, 69, 9–16.CrossRef

Caccamo, D., Curro, M., Ferlazzo, N., Condello, S., & Ientile, R. (2012). Monitoring of transglutaminase2 under different oxidative stress conditions. Amino Acids, 42, 1037–1043.CrossRef

Calani, L., Brighenti, F., Bruni, R., & Del Rio, D. (2012). Absorption and metabolism of milk thistle flavanolignans in humans. Phytomedicine, 20(1), 40–46.CrossRef

Campos, D. A., Madureira, A. R., Gomes, A. M., Sarmento, B., & Pintado, M. M. (2014). Optimization of the production of solid Witepsol nanoparticles loaded with rosmarinic acid. Colloids and Surfaces B: Biointerfaces, 115, 109–117.CrossRef

Cencic, A., & Chingwaru, W. (2010). The role of functional foods, nutraceuticals, and food supplements in intestinal health. Nutrients, 2(6), 611–625.CrossRef

Chakraborty, A., & Dhar, P. (2017). A review on potential of proteins as an excipient for developing a nano-carrier delivery system. Critical Reviews in Therapeutic Drug Carrier Systems, 34(5), 453–488.

Choudhary, M., & Tomer, V. (2013). Cardioprotective effect of nutraceuticals—The emerging evidences. Proceedings of the Indian National Science Academy, 79(4), 985–996.

Criado, P., Fraschini, C., Salmieri, S., Becher, D., Safrany, A., & Lacroix, M. (2016). Free radical grafting of gallic acid (GA) on cellulose nanocrystals (CNCS) and evaluation of antioxidant reinforced gellan gum films. Radiation Physics and Chemistry, 118, 61–69.CrossRef

da Silva Malheiros, P., Daroit, D. J., & Brandelli, A. (2010). Food applications of liposome-encapsulated antimicrobial peptides. Trends in Food Science & Technology, 21(6), 284–292.CrossRef

Davi, G., Santilli, F., & Patrono, C. (2010). Nutraceuticals in diabetes and metabolic syndrome. Cardiovascular Therapeutics, 28(4), 216–226.CrossRef

De Felice, S. L. (1995). The nutraceutical revolution: Its impact on food industry R&D. Trends in Food Science & Technology, 6(2), 59–61.CrossRef

Dissanayake, M., & Vasiljevic, T. (2009). Functional properties of whey proteins affected by heat treatment and hydrodynamic high-pressure shearing. Journal of Dairy Science, 92, 1387–1397.CrossRef

Doktorovova, S., Souto, E. B., & Silva, A. M. (2014). Nanotoxicology applied to solid lipid nanoparticles and nanostructured lipid carriers—A systematic review of in vitro data. European Journal of Pharmaceutics and Biopharmaceutics, 87(1), 1–18.CrossRef

Duncan, T. V. (2011). Applications of nanotechnology in food packaging and food safety: Barrier materials, antimicrobials and sensors. Journal of Colloid and Interface Science, 363, 1–24.CrossRef

Eggersdorfer, M., & Wyss, A. (2018). Carotenoids in human nutrition and health. Archives of Biochemistry and Biophysics, 652, 18–26.CrossRef

El-Leithy, E. S., Makky, A. M., Khattab, A. M., & Hussein, D. G. (2018). Optimization of nutraceutical coenzyme Q10 nanoemulsion with improved skin permeability and anti-wrinkle efficiency. Drug Development and Industrial Pharmacy, 44(2), 316–328.CrossRef

Frede, K., Henze, A., Khalil, M., Baldermann, S., Schweigert, F. J., & Rawel, H. (2014). Stability and cellular uptake of lutein-loaded emulsions. Journal of Functional Foods, 8, 118–127.CrossRef

Gao, Z., Spilk, S., Momen, A., Muller, M. D., Leuenberger, U. A., & Sinoway, L. I. (2012). Vitamin C prevents hyperoxia-mediated coronary vasoconstriction and impairment of myocardial function in healthy subjects. European Journal of Applied Physiology, 112, 483–492.CrossRef

Ghosh, A., Mandal, A. K., Sarkar, S., & Das, N. (2011). Hepatoprotective and neuroprotective activity of liposomal quercetin in combating chronic arsenic induced oxidative damage in liver and brain of rats. Drug Delivery, 18, 451–459.CrossRef

Gopi, S., Amalraj, A., Haponiuk, J. T., & Thomas, S. (2016). Introduction of nanotechnology in herbal drugs and nutraceutical: A review. Journal of Nanomedicine and Biotherapeutic Discovery, 6, 143.CrossRef

Gosal, W. S., Clark, A. H., & Ross-Murphy, S. B. (2004). Fibrillar β-lactoglobulin gels: Part 1. Fibril Formation and Structure. Biomacromolecules, 5, 2408–2419.CrossRef

Grishkewich, N., Mohammed, N., Tang, J., & Tam, K. C. (2017). Recent advances in the application of cellulose nanocrystals. Current Opinion in Colloid & Interface Science, 29, 32–45.CrossRef

Gunasekaran, S., Xiao, L., & OuldEleya, M. M. (2006). Whey protein concentrate hydrogels as bioactive carriers. Journal of Applied Polymer Science, 99, 2470–2476.CrossRef

Huq, T., Fraschini, C., Khan, A., Riedl, B., Bouchard, J., & Lacroix, M. (2017). Alginate based nanocomposite for microencapsulation of probiotic: Effect of cellulose nanocrystal (CNC) and lecithin. Carbohydrate Polymers, 168, 61–69.CrossRef

Huq, T., Vu, K. D., Riedl, B., Bouchard, J., Han, J., & Lacroix, M. (2016). Development of probiotic tablet using alginate, pectin, and cellulose nanocrystals as excipients. Cellulose, 23(3), 1967–1978.CrossRef

Ipsen, R., & Otte, J. (2007). Self-assembly of partially hydrolysed alpha-lactalbumin. Biotechnology Advances, 25, 602–605.CrossRef

Javed, S., Kohli, K., & Ali, M. (2011). Reassessing bioavailability of silymarin. Alternative Medicine Review, 16(3), 239.

Kanoujia, J., Singh, M., Singh, P., & Saraf, S. A. (2016). Novel genipin crosslinked atorvastatin loaded sericin nanoparticles for their enhanced antihyperlipidemic activity. Materials Science and Engineering C: Materials for Biological Applications, 69, 967–976.CrossRef

Khan, A., Wen, Y., Huq, T., & Ni, Y. (2017). Cellulosic nanomaterials in food and nutraceutical applications: A review. Journal of Agriculture and Food Chemistry, 66(1), 8–19.CrossRef

Klyachko, N. L., Manickam, D. S., Brynskikh, A. M., Uglanova, S. V., Li, S., Higginbotham, S. M., et al. (2012). Crosslinked antioxidant nanozymes for improved delivery to CNS. Nanomedicine, 8, 119–129.CrossRef

Lee, D. M., Jackson, K. W., Knowlton, N., Wages, J., Alaupovic, P., Samuelsson, O., et al. (2011). Oxidative stress and inflammation in renal patients and healthy subjects. PLoS ONE, 6, e22360.CrossRef

Li, B., Du, W., Jin, J., & Du, Q. (2012a). Preservation of (-)-epigallocatechin-3-gallate antioxidant properties loaded in heat treated β-lactoglobulin nanoparticles. Journal of Agricultural and Food Chemistry, 60, 3477–3484.CrossRef

Li, N., Han, Z., Li, L., Zhang, B., Liu, Z., & Li, J. (2018). The anti-cataract molecular mechanism study in selenium cataract rats for baicalin ophthalmic nanoparticles. Drug Design, Development and Therapy, 12, 1399.CrossRef

Li, Y., Xiao, H., & McClements, D. J. (2012b). Encapsulation and delivery of crystalline hydrophobic nutraceuticals using nanoemulsions: Factors affecting polymethoxyflavone solubility. Food Biophysics, 7(4), 341–353.CrossRef

Lin, N., Huang, J., & Dufresne, A. (2012). Preparation, properties and applications of polysaccharide nanocrystals in advanced functional nanomaterials: A review. Nanoscale, 4(11), 3274.CrossRef

McClements, D. J., & Rao, J. (2011). Food-grade nanoemulsions: Formulation, fabrication, properties, performance, biological fate, and potential toxicity. Critical Reviews in Food Science and Nutrition, 51(4), 285–330.CrossRef

Mehrad, B., Ravanfar, R., Licker, J., Regenstein, J. M., & Abbaspourrad, A. (2018). Enhancing the physicochemical stability of β-carotene solid lipid nanoparticle (SLNP) using whey protein isolate. Food Research International, 105, 962–969.CrossRef

Mohammadi, M., Pezeshki, A., Mesgari Abbasi, M., Ghanbarzadeh, B., & Hamishehkar, H. (2017). Vitamin D3-loaded nanostructured lipid carriers as a potential approach for fortifying food beverages; in vitro and in vivo evaluation. Advanced Pharmaceutical Bulletin, 7(1), 61–71.CrossRef

Mozafari, M. R. (2005). Liposomes: An overview of manufacturing techniques. Cellular & Molecular Biology Letters, 10(4), 711–719.

Mukherjee, S., Ray, S., & Thakur, R. S. (2009). Solid lipid nanoparticles: A modern formulation approach in drug delivery system. Indian Journal of Pharmaceutical Sciences, 71(4), 349.CrossRef

Muller, R. H., & Keck, C. M. (2004). Challenges and solutions for the delivery of biotech drugs—A review of drug nanocrystal technology and lipid nanoparticles. Journal of Biotechnology, 113, 151–170.CrossRef

Muller, R. H., Radtke, M., & Wissing, S. A. (2002). Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in cosmetic and dermatological preparations. Advanced Drug Delivery Reviews, 54, S131–S155.CrossRef

Nacka, F., Cansell, M., Meleard, P., & Combe, N. (2001). Incorporation of alpha-tocopherol in marine lipid-based liposomes: In vitro and in vivo studies. Lipids, 36, 1313–1320.CrossRef

Najafian, L., & Babji, A. S. (2012). A review of fish-derived antioxidant and antimicrobial peptides: Their production, assessment, and applications. Peptides, 33, 178–185.CrossRef

Nicolai, T., & Durand, D. (2013). Controlled food protein aggregation for new functionality. Current Opinion in Colloid & Interface Science, 18, 249–256.CrossRef

Niki, E. (2014). Role of vitamin E as a lipid-soluble peroxyl radical scavenger: In vitro and in vivo evidence. Free Radical Biology and Medicine, 66, 3–12.CrossRef

Pandey, M., Verma, R. K., & Saraf, S. A. (2010). Nutraceuticals: New era of medicine and health. Asian Journal of Pharmaceutical and Clinical Research, 3(1), 11–15.

Prasad, S., Gupta, S. C., & Tyagi, A. K. (2017). Reactive oxygen species (ROS) and cancer: Role of antioxidative nutraceuticals. Cancer Letters, 387, 95–105.CrossRef

Ramezanzade, L., Hosseini, S. F., & Nikkhah, M. (2017). Biopolymer-coated nanoliposomes as carriers of rainbow trout skin-derived antioxidant peptides. Food Chemistry, 234, 220–229.CrossRef

Rashidinejad, A., Birch, E. J., Sun-Waterhouse, D., & Everett, D. W. (2014). Delivery of green tea catechin and epigallocatechin gallate in liposomes incorporated into low-fat hard cheese. Food Chemistry, 156, 176–183.CrossRef

Relkin, P., & Shukat, R. (2012). Food protein aggregates as vitamin-matrix carriers: Impact of processing conditions. Food Chemistry, 134, 2141–2148.CrossRef

Riemann, A., Schneider, B., Ihling, A., Nowak, M., Sauvant, C., Thews, O., & Gekle, M. (2011). Acidic environment leads to ROS-induced MAPK signaling in cancer cells. PLoS ONE, 6, e22445

Sadeghi, R., Kalbasi, A., Emam-jomeh, Z., Razavi, S. H., Kokini, J., & Moosavi-Movahedi, A. A. (2013). Biocompatible nanotubes as potential carrier for curcumin as a model bioactive compound. Journal of Nanoparticle Research, 15, 1–11.CrossRef

Severino, P., Andreani, T., Macedo, A. S., FangueiroJF, Santana M. H. A., Silva, A. M., & Souto, E. B. (2012). Current state-of-art and new trends on lipid nanoparticles (SLN and NLC) for oral drug delivery. Journal of Drug Delivery, 12, 1–10.CrossRef

Shah, A. V., Desai, H. H., Thool, P., Dalrymple, D., & Serajuddin, A. T. (2018). Development of self-microemulsifying drug delivery system for oral delivery of poorly water-soluble nutraceuticals. Drug Development and Industrial Pharmacy, 44(6), 895–901.CrossRef

Shahidi, F., & Li, Q. (2014). Biologically active peptides from foods. Applied Food Protein Chemistry, 75–98.

Shinde, N., Bangar, B., Deshmukh, S., & Kumbhar, P. (2014). Nutraceuticals: A review on current status. Research Journal of Pharmacy and Technology, 7(1), 1–5.

Shoji, Y., & Nakashima, H. (2004). Nutraceutics and delivery systems. Journal of Drug Targeting, 12, 385–391.CrossRef

Shpigelman, A., Cohen, Y., & Livney, Y. D. (2012). Thermally-induced β-lactoglobulin-EGCG nanovehicles: Loading, stability, sensory and digestive-release study. Food Hydrocolloids, 29, 57–67.CrossRef

Singh, M., Kanoujia, J., Parashar, P., Arya, M., Tripathi, C. B., Sinha, V. R., et al. (2018). Augmented bioavailability of felodipine through an α-linolenic acid-based microemulsion. Drug Delivery and Translational Research, 8(1), 204–225.CrossRef

Singh, M., Kanoujia, J., Singh, P., Tripathi, C. B., Arya, M., Parashar, P., et al. (2016a). Development of an α-linolenic acid containing soft nanocarrier for oral delivery: In vitro and in vivo evaluation. RSC Advances, 81, 77590–77602.CrossRef

Singh, P., Singh, M., Kanoujia, J., Arya, M., Saraf, S. K., & Saraf, S. A. (2016b). Process optimization and photostability of silymarin nanostructured lipid carriers: Effect on UV-irradiated rat skin and SK-MEL 2 cell line. Drug Delivery and Translational Research, 6(5), 597–609.CrossRef

Sinha, V. R., & Kumria, R. (2001). Polysaccharides in colon-specific drug delivery. International Journal of Pharmaceutics, 224, 19–38.CrossRef

Sivakumar, M., Tang, S. Y., & Tan, K. W. (2014). Cavitation technology—A greener processing technique for the generation of pharmaceutical nanoemulsions. Ultrasonics Sonochemistry, 21, 2069–2083.

Solans, C., Izquierdo, P., Nolla, J., Azemar, N., & Garcia-Celma, M. J. (2005). Nanoemulsions. Current Opinion in Colloid & Interface Science, 10(3–4), 102–110.CrossRef

Souyoul, S. A., Saussy, K. P., & Lupo, M. P. (2018). Nutraceuticals: A review. Dermatologic Therapy, 1–12.

Spernath, A., & Aserin, A. (2006). Microemulsions as carriers for drugs and nutraceuticals. Advances in Colloid and Interface Science, 128, 47–64.

Takahashi, M., Uechi, S., Takara, K., Asikin, Y., & Wada, K. (2009). Evaluation of an oral carrier system in rats: Bioavailability and antioxidant properties of liposome-encapsulated curcumin. Journal of Agriculture and Food Chemistry, 57, 9141–9146.CrossRef

Takechi, R., Pallebage-Gamarallage, M. M., Lam, V., Giles, C., & Mamo, J. C. (2013). Nutraceutical agents with anti-inflammatory properties prevent dietary saturated-fat induced disturbances in blood–brain barrier function in wild-type mice. Journal of Neuroinflammation, 10(1), 842.CrossRef

Tan, C., Xue, J., Lou, X., Abbas, S., Guan, Y., Feng, B., et al. (2014). Liposomes as delivery systems for carotenoids: Comparative studies of loading ability, storage stability and in vitro release. Food Function, 5(6), 1232–1240.CrossRef

Tasset, I., Pontes, A. J., Hinojosa, A. J., de la Torre, R., & Tunez, I. (2011). Olive oil reduces oxidative damage in a 3-nitropropionic acid-induced Huntington’s disease-like rat model. Nutritional Neuroscience, 14, 106–111.

Tian, Y. Y., Ge, L., Duan, X. L., Gao, Z. Q., & Chang, Y. Z. (2007). Lycopene liposomes: Lycopene release in vitro and pharmaceutical behaviors and antioxidation in vivo. Yao Xue Xue Bao, 42, 1107–1111.

Ting, Y. W., Jiang, Y., Ho, C. T., & Huang, Q. R. (2014). Common delivery systems for enhancing in vivo bioavailability and biological efficacy of nutraceuticals. Journal of Functional Foods, 7, 112–128.CrossRef

Tripathi, C. B., Parashar, P., Arya, M., Singh, M., Kanoujia, J., Kaithwas, G., et al. (2018). QbD-based development of α-linolenic acid potentiated nanoemulsion for targeted delivery of doxorubicin in DMBA-induced mammary gland carcinoma: In vitro and in vivo evaluation. Drug Delivery and Translational Research, 10, 1–22.

Ullah, H., Wahid, F., Santos, H. A., & Khan, T. (2016). Advances in biomedical and pharmaceutical applications of functional bacterial cellulose-based nanocomposites. Carbohydrate Polymers, 150, 330–352.CrossRef

Vakilinezhad, M. A., Tanha, S., Montaseri, H., Dinarvand, R., Azadi, A., & Javar, H. A. (2018). Application of response surface method for preparation, optimization, and characterization of nicotinamide loaded solid lipid nanoparticles. Advanced Pharmaceutical Bulletin, 8(2), 245.CrossRef

Wagoner, J., Morishima, C., Graf, T. N., Oberlies, N. H., Teissier, E., Pecheur, E. I., et al. (2011). Differential in vitro effects of intravenous versus oral formulations of silibinin on the HCV life cycle and inflammation. PLoS ONE, 6, e16464.CrossRef

Wang, D., Zhao, P., Cuia, F., & Li, X. (2007). Preparation and characterization of solid lipid nanoparticles loaded with total flavones of Hippophae rhamnoides (TFH). PDA Journal of Pharmaceutical Science and Technology, 61, 110–120.

Wang, Y., Xu, H., Fu, Q., Ma, R., & Xiang, J. (2011). Protective effect of resveratrol derived from Polygonum cuspidatum and its liposomal form on nigral cells in Parkinsonian rats. Journal of the Neurological Sciences, 304, 29–34.CrossRef

Weber, S., Zimmer, A., & Pardeike, J. (2014). Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for pulmonary application: A review of the state of the art. European Journal of Pharmaceutics and Biopharmaceutics, 86, 7–22.CrossRef

Xianquan, S., Shi, J., Kakuda, Y., & Yueming, J. (2005). Stability of lycopene during food processing and storage. Journal of Medicinal Food, 8(4), 413–422.CrossRef

Yi, J., Liu, Y., Zhang, Y., & Gao, L. (2018). Fabrication of resveratrol-loaded whey protein-dextran colloidal complex for the stabilization and delivery of β-carotene emulsions. Journal of Agriculture and Food Chemistry, 66(36), 9481–9489.CrossRef

Yu, H., & Huang, Q. (2012). Improving the oral bioavailability of curcumin using novel organogel-based nanoemulsions. Journal of Agriculture and Food Chemistry, 60(21), 5373–5379.CrossRef

Zheng, Y., Monty, J., & Linhardt, R. J. (2015). Polysaccharide-based nanocomposites and their applications. Carbohydrate Research, 405, 23–32.CrossRef

Zimet, P., & Livney, Y. D. (2009). Beta-lactoglobulin and its nanocomplexes with pectin as vehicles for ω-3 polyunsaturated fatty acids. Food Hydrocolloids, 23, 1120–1126.CrossRef

Title: Nanomaterials in Nutraceuticals Applications
Authors: Mahendra Singh
Navneeta Singh
Balakumar Chandrasekaran
Pran Kishore Deb
Publisher: Springer International Publishing
Book: Integrative Nanomedicine for New Therapies
Print ISBN: 978-3-030-36259-1

Electronic ISBN: 978-3-030-36260-7

Copyright Year: 2020
DOI: https://doi.org/10.1007/978-3-030-36260-7_14

Springer Professional

Abstract

Please log in to get access to your license.

Dont have a licence yet? Then find out more about our products and how to get one now:

Springer Professional "Wirtschaft+Technik"

Springer Professional "Technik"

Premium Partners