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Journal of Nanoparticle Research
Published in: Journal of Nanoparticle Research 10/2022

01-10-2022 | Review

Nanotechnology-based approaches in diagnosis and treatment of epilepsy

Authors: Tina Sepasi, Tahereh Ghadiri, Farhad Bani, Abbas Ebrahimi-Kalan, Sina Khodakarimi, Amir Zarebkohan, Ali Gorji

Published in: Journal of Nanoparticle Research | Issue 10/2022

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Abstract

Over 70 million people worldwide are suffering from different forms of epilepsy. Despite significant advances in the past few decades, between 20 and 40% of these patients would develop medically intractable epilepsy. Technological advances are essential in the identification of novel reliable diagnostic and therapeutic approaches and in improving the quality of health services for patients with epilepsy. Nanotechnology-based approaches offer potential effective methods to improve seizure detection and treatment. Nanomedicine-based nanoparticles can promote anti-convulsant therapy through improving pharmacokinetics and biodistribution of drugs as well as providing more efficient drugs and active molecule delivery systems. Furthermore, nanotechnology-based approaches can tackle barriers to a better diagnosis of epilepsy via the improvement of bioelectrical recording approaches as well as the development of novel biomarkers and imaging systems. In the present review, we summarized the current nanotechnology-based advances in the diagnosis and treatment of epilepsy and discussed how the knowledge of these achievements could convey a better treatment outcome in epilepsy.
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Metadata
Title
Nanotechnology-based approaches in diagnosis and treatment of epilepsy
Authors
Tina Sepasi
Tahereh Ghadiri
Farhad Bani
Abbas Ebrahimi-Kalan
Sina Khodakarimi
Amir Zarebkohan
Ali Gorji
Publication date
01-10-2022
Publisher
Springer Netherlands
Published in
Journal of Nanoparticle Research / Issue 10/2022
Print ISSN: 1388-0764
Electronic ISSN: 1572-896X
DOI
https://doi.org/10.1007/s11051-022-05557-6

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