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Vehicles Are Lazy: On Predicting Vehicle Transient Dynamics by Steady-State Responses Read chapter Read first chapter

2020 | OriginalPaper | Chapter

4. Nonlinear Modeling Application to Micro-/Nanorobotics

Authors : Ali Ghanbari, Mohsen Bahrami

Published in: Nonlinear Approaches in Engineering Applications

Publisher: Springer International Publishing

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Abstract

Micro-/nanorobots have the potential to revolutionize medicine by specific applications, such as targeted drug delivery, biopsy, hyperthermia, brachytherapy, scaffolding, in vivo ablation, sensing, marking, and stem cell therapy. Application of microrobots can move us to the stage that monitoring diseases, precise localized drug delivery, minimally invasive surgery, and novel therapies such as stem cell therapy are done using the tools inside the human body.
Since size is small and velocity is low, microrobots have a very low Reynolds (Re) number. A low Re number indicates the dominance of viscous forces and hence, swimming methodologies at microscale are different from those at the macroscale. Although motion of these microrobots is linear at Stokes flow, hydrodynamics of flagella and cilia involve nonlinear models that should be addressed for precise actuation and control of micro-/nanorobots. Nonlinear modeling is of great significance especially when the artificial filaments are fabricated from soft materials to mimic natural flagella and cilia and provide enhanced propulsion.
A great challenge in developing an autonomous microrobotic system is to provide power and control for the microrobot. Since untethered microrobots can be used as implants and have a higher maneuverability, the control system should benefit from a wireless actuation mechanism. Magnetic actuation can transfer a reasonable amount of power wirelessly. There are different systems for generating magnetic field and gradients:
• Permanent magnets
• Helmholtz coils, Maxwell coils, or a combination thereof
• Magnetic resonance imaging (MRI) systems
• Customized sets of electromagnetic coils

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Literature
1.
Nelson, B. J., Kaliakatsos, I. K., & Abbott, J. J. (2010). Microrobots for minimally invasive medicine. Annual Review of Biomedical Engineering, 12, 55–85.CrossRef
2.
Sitti, M., Giltinan, J., & Yim, S. (2015). Biomedical applications of untethered mobile milli/microrobots. Proceedings of the IEEE, 103, 205–224.CrossRef
3.
Ceylan, H., Giltinan, J., Kozielskia, K., & Sitti, M. (2017). Mobile microrobots for bioengineering applications. Lab on a Chip, 17, 1705–1724.CrossRef
4.
Chen, X. Z., Hoop, M., Mushtaq, F., Siringil, E., Hu, C., Nelson, B. J., & Pané, S. (2017). Recent developments in magnetically driven micro- and nanorobots. Applied Materials Today, 9, 37–48.CrossRef
5.
Ghanbari, A., Bahrami, M., & Nobari, M. R. H. (2011). Methodology for artificial microswimming using magnetic actuation. Physical Review E, 83, 046301.CrossRef
6.
Ghanbari, A., & Bahrami, M. (2011). A novel swimming microrobot based on artificial cilia for biomedical applications. Journal of Intelligent and Robotic Systems, 63, 399–416.CrossRef
7.
Zhang, L., Abbott, J. J., Dong, L., Kratochvil, B. E., Bell, D., & Nelson, B. J. (2009). Artificial bacterial flagella: fabrication and magnetic control. Applied Physics Letters, 94, 064107.CrossRef
8.
Abbott, J. J., Peyer, K. E., Lagomarsino, M. C., Zhang, L., Dong, L., Kaliakatsos, I. K., & Nelson, B. J. (2009). How should microrobots swim? International Journal of Robotics Research, 28, 1434–1447.CrossRef
9.
Huang, H., Chao, Q., Sakar, M. S., & Nelson, B. J. (2017). Optimization of tail geometry for the propulsion of soft microrobots. IEEE Robotics and Automation Letters, 2, 727–732.CrossRef
10.
Martel, S., Mohammadi, M., Felfoul, O., Lu, Z., & Pouponneau, P. (2009). Flagellated magnetotactic bacteria as controlled MRI-trackable propulsion and steering systems for medical nanorobots operating in the human microvasculature. International Journal of Robotics Research, 28, 571–582.CrossRef
11.
Martel, S., Felfoul, O., Mathieu, J., Chanu, A., Tamaz, S., Mohammadi, M., Mankiewicz, M., & Tabatabaei, N. (2009). MRI-based medical nanorobotic platform for the control of magnetic nanoparticles and flagellated bacteria for target interventions in human capillaries. International Journal of Robotics Research, 28, 1169–1182.CrossRef
12.
Kummer, M. P., Abbott, J. J., Kratochvil, B. E., Borer, R., Sengul, A., & Nelson, B. J. (2010). Octomag: An electromagnetic system for 5-DOF wireless micromanipulation. IEEE Transactions on Robotics, 26, 1006–1017.CrossRef
13.
Schuerle, S., Erni, S., Flink, M., Kratochvil, B. E., & Nelson, B. J. (2013). Three-dimensional magnetic manipulation of micro-and nanostructures for applications in life sciences. IEEE Transactions on Magnetics, 49, 321–330.CrossRef
14.
Zhang, Z., & Menq, C. H. (2011). Design and modeling of a 3-D magnetic actuator for magnetic microbead manipulation. IEEE/ASME Transactions on Mechatronics, 16, 421–430.CrossRef
15.
Grady, M. S., Howard, M. A., III, Molloy, J. A., Ritter, R. C., Quate, E. G., & Gillies, G. T. (1990). Nonlinear magnetic stereotaxis: three dimensional, in vivo remote magnetic manipulation of a small object in canine brain. Medical Physics, 17, 405–415.CrossRef
16.
Taylor, G. I. (1951). Analysis of the swimming of microscopic organisms. Proceedings of the Royal Society of London. Series A: Mathematical and Physical Sciences, A209, 447–461.MathSciNetMATH
17.
Gray, J., & Hancock, G. (1955). The propulsion of sea-urchin spermatozoa. Journal of Experimental Biology, 32, 802–814.
18.
Brokaw, C. J. (1970). Bending moments in free-swimming flagella. Journal of Experimental Biology, 53, 445–464.
19.
Gueron, S., & Liron, N. (1992). Ciliary motion modeling, and dynamic multicilia interactions. Biophysical Journal, 63, 1045–1058.CrossRef
20.
Childress, S. (1981). Mechanics of swimming and flying. New York: Cambridge University Press.CrossRef
21.
Lighthill, J. L. (1975) Mathematical biofluiddynamics. In Regional Conference Series in Applied Mathematics, SIAM (pp. 45–62).
22.
Johnson, R. E., & Brokaw, C. J. (1979). Flagellar hydrodynamics: a comparison between resistive-force theory and slender-body theory. Biophysical Journal, 25, 113–127.CrossRef
23.
Gueron, S., & Levit-Gurevich, K. (1998). Computation of the internal forces in cilia: application to ciliary motion, the effects of viscosity, and ciliainteractions. Biophysical Journal, 74, 1658–1676.CrossRef
24.
Brennen, C., & Winet, H. (1977). Fluid mechanics of propulsion by cilia and flagella. Annual Review of Fluid Mechanics, 9, 339–398.CrossRef
25.
Feng, J., Joseph, D. D., Glowinski, R., & Pan, T. W. (1995). A three-dimensional computation of the force and torque on an ellipsoid settling slowly through a viscoelastic fluid. Journal of Fluid Mechanics, 283, 1–16.MathSciNetCrossRef
26.
Kim, S., Lee, S., Lee, J., Nelson, B. J., Zhang, L., & Choi, H. (2016). Fabrication and manipulation of ciliary microrobots with non-reciprocal magnetic actuation. Scientific Reports, 6, 30713.CrossRef
27.
Gibbons, I. R. (1981). Cilia and flagella of eukaryotes. Journal of Cell Biology, 91, 107s–124s.CrossRef
28.
Sleigh, M. A. (1962). The biology of cilia and flagella. Oxford: Pergamon Press.
29.
Sleigh, M. A. (1968) Patterns of ciliary beating. In Aspects of cell motility (22nd Symposium of the Society for Experimental Biology) (pp. 131–150).
30.
Peyer, K. E., Zhang, L., & Nelson, B. J. (2013). Bio-inspired magnetic swimming microrobots for biomedical applications. Nanoscale, 5, 1259–1272.CrossRef
31.
Kim, S., Qiu, F., Kim, S., Ghanbari, A., Moon, C., Zhang, L., Nelson, B. J., & Choi, H. (2013). Fabrication and characterization of magnetic microrobots for three-dimensional cell culture and targeted transportation. Advanced Materials, 25, 5863–5868.CrossRef
32.
Ghanbari, A., Chang, P. H., Nelson, B. J., & Choi, H. (2014). Electromagnetic steering of a magnetic cylindrical microrobot using optical feedback closed-loop control. International Journal of Optomechatronics, 8, 129–145.CrossRef
33.
Evans, B. A., Shields, A. R., Lloyd Carroll, R., Washburn, S., Falvo, M. R., & Superfine, R. (2007). Magnetically actuated nanorod arrays as biomimetic cilia. Nano Letters, 7, 1428–1434.CrossRef
34.
Goubault, C. (2003). Flexible magnetic filaments as micromechanical sensors. Physical Review Letters, 91, 260802.CrossRef
35.
Roper, M., Dreyfus, R., Baudry, J., Fermigier, M., Bibette, J., & Stone, H. A. (2006). On the dynamics of magnetically driven elastic filaments. Journal of Fluid Mechanics, 554, 167–190.MathSciNetCrossRef
36.
Ghanbari, A., Chang, P. H., Nelson, B. J., & Choi, H. (2014). Magnetic actuation of a cylindrical microrobot using time-delay-estimation closed-loop control: modeling and experiments. Smart Materials and Structures, 23, 035013.CrossRef
37.
Metadata
Title
Nonlinear Modeling Application to Micro-/Nanorobotics
Authors
Ali Ghanbari
Mohsen Bahrami
Copyright Year
2020
Book
Nonlinear Approaches in Engineering Applications

Print ISBN: 978-3-030-18962-4

Electronic ISBN: 978-3-030-18963-1

Copyright Year: 2020

DOI
https://doi.org/10.1007/978-3-030-18963-1_4

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