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Published in:
2006 | OriginalPaper | Chapter
On Genome Evolution with Innovation
Authors : Damian Wójtowicz, Jerzy Tiuryn
Published in: Mathematical Foundations of Computer Science 2006
Publisher: Springer Berlin Heidelberg
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We introduce and analyse a simple probabilistic model of genome evolution. It is based on three fundamental evolutionary events: gene
d
uplication,
l
oss and
i
nnovation, and it is called
DLI model
. The focus of the paper is around the size distribution of gene families. The formulas for equilibrium gene family sizes are derived showing that they follow a logarithmic distribution. We consider also a disjoint union of DLI models and we present the result of this study. Some empirical results for microbial genomes are presented.