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Multistep Continuous-Flow Processes for the Preparation of Heterocyclic Active Pharmaceutical Ingredients Read chapter Read first chapter

2018 | OriginalPaper | Chapter

Photochemical Synthesis of Heterocycles: Merging Flow Processing and Metal-Catalyzed Visible Light Photoredox Transformations

Author : Toma Glasnov

Published in: Flow Chemistry for the Synthesis of Heterocycles

Publisher: Springer International Publishing

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Abstract

The ubiquitous presence of heterocyclic moieties in everyday life justifies the ongoing intensive research within the synthetic community to discover effective methodologies for their construction. As the social concern regarding environmental protection gains importance, the use of light as the ultimate green promoter for chemical reactions has been revived in the scientific community. Specifically, visible-light photoredox processes based on metal- and organic photosensitizer are attracting significant attention and have seen an exceptional advance recently.
Additionally, continuous-flow processing has enabled a safer and more efficient generation of various heterocycles, whilst allowing their syntheses in a scalable manner. In this chapter, recent achievements in the area of continuous-flow aided photoredox synthesis are covered, including some general remarks on instrumentation, theoretical background and selected flow UV-photochemistry examples.

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Metadata
Title
Photochemical Synthesis of Heterocycles: Merging Flow Processing and Metal-Catalyzed Visible Light Photoredox Transformations
Author
Toma Glasnov
Copyright Year
2018
Book
Flow Chemistry for the Synthesis of Heterocycles

Print ISBN: 978-3-319-94327-5

Electronic ISBN: 978-3-319-94328-2

Copyright Year: 2018

DOI
https://doi.org/10.1007/7081_2018_20