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2024 | OriginalPaper | Chapter

Platinum Nanoparticles in Biomedical Applications: Antibacterial and Antiviral Perspectives

Authors : S. Shiva Samhitha, Srivathsava Surabhi, Sai Keerthi Saireddy, G. Santhosh

Published in: Nanoparticles in Modern Antimicrobial and Antiviral Applications

Publisher: Springer International Publishing

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Abstract

Transition metals, e.g., platinum (Pt), possess unique physicochemical and biological characteristics due to the presence of half-filled d-orbitals, with which they can exhibit variable oxidation states and catalytic ability and they can form complex and colored compounds. Besides, they display exceptional surficial properties that play a vital role in automobile catalytic converters and petrochemical cracking applications. However, catalysis is versatile and pivotal among the others that attracted attention owing to its diversity, which is further categorized as homogeneous, heterogeneous, and biocatalysts in terms of their functionality. Owing to their distinctive hard complex, heavy, and less-reactive nature, Pt nanoparticles (NPs) are very good catalytic materials and their compounds attracted considerable interest in the biomedical field of applications, such as nanomedicine, photothermal therapy, radiation dose enhancement, computed tomography (CT), and X-ray. Furthermore, Pt-based materials possess excellent antioxidant, antibacterial, antiviral, and anticancer nature, enabling them as nanocarriers, nanozymes, and nanosensors for diagnostic purposes. Cancer is one of the most intensely researched fields, where Pt derivatives, such as cisplatin, carboplatin, and oxaliplatin, are widely utilized in clinical research to combat various drug-resistant bacteria and to lessen the undesirable side effects of radiation and chemotherapy. Pt-based compounds have great potential and their drugs are being examined extensively ever since their anticancer activity was discovered. They have unexplored potential for the fabrication of drugs that are useful for viral infections. As a result, several novel Pt compounds were produced, some of which have intriguing antiviral characteristics. This chapter aims to demonstrate the potential use of Pt NPs in antibacterial and antiviral applications.

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Literature
go back to reference Abed, A., Derakhshan, M., Karimi, M., Shirazinia, M., Mahjoubin-Tehran, M., Homayonfal, M., Hamblin, M. R., Mirzaei, S. A., Soleimanpour, H., Dehghani, S., Dehkordi, F. F., & Mirzaei, H. (2022). Platinum nanoparticles in biomedicine: Preparation, anti-cancer activity, and drug delivery vehicles. Frontiers in Pharmacology, 13, 1–23. https://doi.org/10.3389/fphar.2022.797804CrossRef Abed, A., Derakhshan, M., Karimi, M., Shirazinia, M., Mahjoubin-Tehran, M., Homayonfal, M., Hamblin, M. R., Mirzaei, S. A., Soleimanpour, H., Dehghani, S., Dehkordi, F. F., & Mirzaei, H. (2022). Platinum nanoparticles in biomedicine: Preparation, anti-cancer activity, and drug delivery vehicles. Frontiers in Pharmacology, 13, 1–23. https://​doi.​org/​10.​3389/​fphar.​2022.​797804CrossRef
go back to reference Gurunathan, S., Jeyaraj, M., Kang, M. H., & Kim, J. H. (2019a). Tangeretin-assisted platinum nanoparticles enhance the apoptotic properties of doxorubicin: Combination therapy for osteosarcoma treatment. Nanomaterials (Basel, Switzerland), 9(8). https://doi.org/10.3390/NANO9081089 Gurunathan, S., Jeyaraj, M., Kang, M. H., & Kim, J. H. (2019a). Tangeretin-assisted platinum nanoparticles enhance the apoptotic properties of doxorubicin: Combination therapy for osteosarcoma treatment. Nanomaterials (Basel, Switzerland), 9(8). https://​doi.​org/​10.​3390/​NANO9081089
go back to reference Hashimoto, M., Yamaguchi, S., Sasaki, J. I., Kawai, K., Kawakami, H., Iwasaki, Y., & Imazato, S. (2016). Inhibition of matrix metalloproteinases and toxicity of gold and platinum nanoparticles in L929 fibroblast cells. European Journal of Oral Sciences, 124(1), 68–74. https://doi.org/10.1111/EOS.12235CrossRefPubMed Hashimoto, M., Yamaguchi, S., Sasaki, J. I., Kawai, K., Kawakami, H., Iwasaki, Y., & Imazato, S. (2016). Inhibition of matrix metalloproteinases and toxicity of gold and platinum nanoparticles in L929 fibroblast cells. European Journal of Oral Sciences, 124(1), 68–74. https://​doi.​org/​10.​1111/​EOS.​12235CrossRefPubMed
go back to reference Konieczny, P., Goralczyk, A. G., Szmyd, R., Skalniak, L., Koziel, J., Filon, F. L., Crosera, M., Cierniak, A., Zuba-Surma, E. K., Borowczyk, J., Laczna, E., Drukala, J., Pyza, E., Semik, D., Woznicka, O., Klein, A., & Jura, J. (2013). Effects triggered by platinum nanoparticles on primary keratinocytes. International Journal of Nanomedicine, 8, 3963–3975. https://doi.org/10.2147/IJN.S49612CrossRefPubMedPubMedCentral Konieczny, P., Goralczyk, A. G., Szmyd, R., Skalniak, L., Koziel, J., Filon, F. L., Crosera, M., Cierniak, A., Zuba-Surma, E. K., Borowczyk, J., Laczna, E., Drukala, J., Pyza, E., Semik, D., Woznicka, O., Klein, A., & Jura, J. (2013). Effects triggered by platinum nanoparticles on primary keratinocytes. International Journal of Nanomedicine, 8, 3963–3975. https://​doi.​org/​10.​2147/​IJN.​S49612CrossRefPubMedPubMedCentral
go back to reference Liu, J.-J., Orlova, N., Oakes, B. L., Ma, E., Spinner, H. B., Baney, K. L. M., Chuck, J., Tan, D., Knott, G. J., Harrington, L. B., Al-Shayeb, B., Wagner, A., Brötzmann, J., Staahl, B. T., Taylor, K. L., Desmarais, J., Nogales, E., & Doudna, J. A. (2019). CasX enzymes comprise a distinct family of RNA-guided genome editors. Nature, 566(7743), 218–223. https://doi.org/10.1038/s41586-019-0908-xCrossRefPubMedPubMedCentral Liu, J.-J., Orlova, N., Oakes, B. L., Ma, E., Spinner, H. B., Baney, K. L. M., Chuck, J., Tan, D., Knott, G. J., Harrington, L. B., Al-Shayeb, B., Wagner, A., Brötzmann, J., Staahl, B. T., Taylor, K. L., Desmarais, J., Nogales, E., & Doudna, J. A. (2019). CasX enzymes comprise a distinct family of RNA-guided genome editors. Nature, 566(7743), 218–223. https://​doi.​org/​10.​1038/​s41586-019-0908-xCrossRefPubMedPubMedCentral
go back to reference Mohammadi, H., Abedi, A., Akbarzadeh, A., Mokhtari, M. J., Shahmabadi, H. E., Mehrabi, M. R., Javadian, S., & Chiani, M. (2013). Evaluation of synthesized platinum nanoparticles on the MCF-7 and HepG-2 cancer cell lines. International Nano Letters, 3(1), 1–5. https://doi.org/10.1186/2228-5326-3-28CrossRef Mohammadi, H., Abedi, A., Akbarzadeh, A., Mokhtari, M. J., Shahmabadi, H. E., Mehrabi, M. R., Javadian, S., & Chiani, M. (2013). Evaluation of synthesized platinum nanoparticles on the MCF-7 and HepG-2 cancer cell lines. International Nano Letters, 3(1), 1–5. https://​doi.​org/​10.​1186/​2228-5326-3-28CrossRef
go back to reference Nishanthi, R., Malathi, S., John Paul, S., & Palani, P. (2019). Green synthesis and characterization of bioinspired silver, gold and platinum nanoparticles and evaluation of their synergistic antibacterial activity after combining with different classes of antibiotics. Materials Science and Engineering: C, 96, 693–707. https://doi.org/10.1016/J.MSEC.2018.11.050CrossRef Nishanthi, R., Malathi, S., John Paul, S., & Palani, P. (2019). Green synthesis and characterization of bioinspired silver, gold and platinum nanoparticles and evaluation of their synergistic antibacterial activity after combining with different classes of antibiotics. Materials Science and Engineering: C, 96, 693–707. https://​doi.​org/​10.​1016/​J.​MSEC.​2018.​11.​050CrossRef
go back to reference Ramkumar, V. S., Pugazhendhi, A., Prakash, S., Ahila, N. K., Vinoj, G., Selvam, S., Kumar, G., Kannapiran, E., & Rajendran, R. B. (2017). Synthesis of platinum nanoparticles using seaweed Padina gymnospora and their catalytic activity as PVP/PtNPs nanocomposite towards biological applications. Biomedicine & Pharmacotherapy, 92, 479–490. https://doi.org/10.1016/J.BIOPHA.2017.05.076CrossRef Ramkumar, V. S., Pugazhendhi, A., Prakash, S., Ahila, N. K., Vinoj, G., Selvam, S., Kumar, G., Kannapiran, E., & Rajendran, R. B. (2017). Synthesis of platinum nanoparticles using seaweed Padina gymnospora and their catalytic activity as PVP/PtNPs nanocomposite towards biological applications. Biomedicine & Pharmacotherapy, 92, 479–490. https://​doi.​org/​10.​1016/​J.​BIOPHA.​2017.​05.​076CrossRef
go back to reference Sung, H., Ferlay, J., Siegel, R. L., Laversanne, M., Soerjomataram, I., Jemal, A., & Bray, F. (2021). Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: a Cancer Journal for Clinicians, 71(3), 209–249. https://doi.org/10.3322/CAAC.21660CrossRefPubMed Sung, H., Ferlay, J., Siegel, R. L., Laversanne, M., Soerjomataram, I., Jemal, A., & Bray, F. (2021). Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: a Cancer Journal for Clinicians, 71(3), 209–249. https://​doi.​org/​10.​3322/​CAAC.​21660CrossRefPubMed
go back to reference Williams, K. R., & Burstein, G. T. (1997). Low temperature fuel cells: Interactions between catalysts and engineering design. Catalysis Today, 38, 401–410.CrossRef Williams, K. R., & Burstein, G. T. (1997). Low temperature fuel cells: Interactions between catalysts and engineering design. Catalysis Today, 38, 401–410.CrossRef
go back to reference Zhao, Y., Chen, F., Pan, Y., Li, Z., Xue, X., Okeke, C. I., Wang, Y., Li, C., Peng, L., Wang, P. C., Ma, X., & Liang, X. J. (2015). Nanodrug formed by Coassembly of dual anticancer drugs to inhibit cancer cell drug resistance. ACS Applied Materials & Interfaces, 7(34), 19295–19305. https://doi.org/10.1021/ACSAMI.5B05347CrossRef Zhao, Y., Chen, F., Pan, Y., Li, Z., Xue, X., Okeke, C. I., Wang, Y., Li, C., Peng, L., Wang, P. C., Ma, X., & Liang, X. J. (2015). Nanodrug formed by Coassembly of dual anticancer drugs to inhibit cancer cell drug resistance. ACS Applied Materials & Interfaces, 7(34), 19295–19305. https://​doi.​org/​10.​1021/​ACSAMI.​5B05347CrossRef
Metadata
Title
Platinum Nanoparticles in Biomedical Applications: Antibacterial and Antiviral Perspectives
Authors
S. Shiva Samhitha
Srivathsava Surabhi
Sai Keerthi Saireddy
G. Santhosh
Copyright Year
2024
DOI
https://doi.org/10.1007/978-3-031-50093-0_3

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