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1992 | OriginalPaper | Chapter

Quantitation of 7-(2-Hydroxyethyl)guanine Produced by Endogenous and Environmental Ethylene Oxide in DNA of Lymphocytes

Authors : H. M. Bolt, H. Peter, M. Leutbecher, H. Ottenwälder, H. W. Goergens, U. Föst

Published in: Environmental Hygiene III

Publisher: Springer Berlin Heidelberg

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Analysis of macromolecular adducts of ethylene oxide is a tool which allows determination of internal target doses of this carcinogen (Bolt et al., 1988). An important aspect is that ethylene is converted in the living organism to ethylene oxide, and that ethylene is produced endogenously (Filser and Bolt, 1983; Schmiedel et al., 1983).

Metadata
Title
Quantitation of 7-(2-Hydroxyethyl)guanine Produced by Endogenous and Environmental Ethylene Oxide in DNA of Lymphocytes
Authors
H. M. Bolt
H. Peter
M. Leutbecher
H. Ottenwälder
H. W. Goergens
U. Föst
Copyright Year
1992
Publisher
Springer Berlin Heidelberg
DOI
https://doi.org/10.1007/978-3-642-77112-5_14