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2013 | OriginalPaper | Chapter

Relevance of Nanotechnology to Africa: Synthesis, Applications, and Safety

Authors : Ndeke Musee, Lucky Sikhwivhilu, Mary Gulumian

Published in: Chemistry for Sustainable Development in Africa

Publisher: Springer Berlin Heidelberg

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Abstract

In this chapter, two nanotechnology-based applications relevant to Africa in promoting sustainability and achievement of the Millennium development goals (MDGs) are presented. The applications comprise the provision of therapeutic treatment of diseases (HIV/AIDS and malaria) and the treatment of contaminated water through purification, remediation, and disinfection process to promote access to clean water to millions of African inhabitants without clean drinking water. Extensive examination of the available scientific literature suggests that nanotechnology can potentially improve the provision of health and water services in the African continent. While the authors agree these benefits are of great relevance to the continent, the chapter gives insights into the concerns related to the potential risks posed by nanotechnology-based products both to humans and other ecological systems. In addition, the chapter seeks to outline the chemistry underpinning the development of nanotechnology and its relevance in achieving sustainable development within the context of developmental challenges in Africa. Finally, as the future socioeconomic status will be mostly defined by nanotechnology capabilities, Africa should be alert to these changes and take advantage, particularly, at this early development phase of nanotechnology development.

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Literature
1.
go back to reference de Heer WA, Bonard J-M, Fauth K et al (1997) Electron field emitters based on carbon nanotube films. Adv Mater 9:87–89 de Heer WA, Bonard J-M, Fauth K et al (1997) Electron field emitters based on carbon nanotube films. Adv Mater 9:87–89
2.
go back to reference Tans SJ, Devoret MH, Dai H et al (1997) Individual single-wall carbon nanotubes as quantum wires. Nature 386:474–477 Tans SJ, Devoret MH, Dai H et al (1997) Individual single-wall carbon nanotubes as quantum wires. Nature 386:474–477
3.
go back to reference Dai H, Hafner JH, Rinzler AG et al (1996) Nanotubes as nanoprobes in scanning probe microscopy. Nature 384:147–150 Dai H, Hafner JH, Rinzler AG et al (1996) Nanotubes as nanoprobes in scanning probe microscopy. Nature 384:147–150
4.
go back to reference Gao G (2004) Synthesis, properties and applications. Imperial College Press, London Gao G (2004) Synthesis, properties and applications. Imperial College Press, London
5.
go back to reference Endo M, Takeuchi K, Igarashi S et al (1993) The production and structure of pyrolytic carbon nanotubes (PCNTs). J Phys Chem Solids 54:1841–1848 Endo M, Takeuchi K, Igarashi S et al (1993) The production and structure of pyrolytic carbon nanotubes (PCNTs). J Phys Chem Solids 54:1841–1848
6.
go back to reference Rinzler AG, Liu J, Dai H et al (1998) Large scale purification of single-wall carbon nanotubes: process, product, and characterization. Appl Phys A 67:29–37 Rinzler AG, Liu J, Dai H et al (1998) Large scale purification of single-wall carbon nanotubes: process, product, and characterization. Appl Phys A 67:29–37
7.
go back to reference Amelinckx S, Zhang XB, Bernaerts D et al (1994) A formation mechanism for catalytically grown helix-shaped graphite nanotubes. Science 265:635–639 Amelinckx S, Zhang XB, Bernaerts D et al (1994) A formation mechanism for catalytically grown helix-shaped graphite nanotubes. Science 265:635–639
8.
go back to reference Setlur AA, Dai JY, Lauerhaas JM, Chang RPH (1998) Formation of filled carbon nanotubes and nanoparticles using polycyclic aromatics hydrocarbon molecules. Carbon 36:721–723 Setlur AA, Dai JY, Lauerhaas JM, Chang RPH (1998) Formation of filled carbon nanotubes and nanoparticles using polycyclic aromatics hydrocarbon molecules. Carbon 36:721–723
9.
go back to reference Bladh K, Falk LKL, Rohmund F (2000) On the iron-catalysed growth of single-walled carbon nanotubes and encapsulated metal particles in the gas phase. Appl Phys A Mater Sci Process 70:317–322 Bladh K, Falk LKL, Rohmund F (2000) On the iron-catalysed growth of single-walled carbon nanotubes and encapsulated metal particles in the gas phase. Appl Phys A Mater Sci Process 70:317–322
10.
go back to reference Diener MD, Nichelson N, Alford JM (2000) Synthesis of single-walled carbon nanotubes in flames. J Phys Chem B 2000 104:9615–9620 Diener MD, Nichelson N, Alford JM (2000) Synthesis of single-walled carbon nanotubes in flames. J Phys Chem B 2000 104:9615–9620
11.
go back to reference Loiseau A, Willaime F (2000) Filled and mixed nanotubes: from TEM studies to the growth mechanism within a phase-diagram approach. Appl Surf Sci 164:227–240 Loiseau A, Willaime F (2000) Filled and mixed nanotubes: from TEM studies to the growth mechanism within a phase-diagram approach. Appl Surf Sci 164:227–240
12.
go back to reference Puddephatt RJ (1978) The chemistry of gold. Elsevier Science, Amsterdam Puddephatt RJ (1978) The chemistry of gold. Elsevier Science, Amsterdam
13.
go back to reference Hyatt AD, Eaton BT (eds) (1993) Immune-gold electron microscopy in virus diagnosis and research, CRC Press. Boca Raton, pp 178–454 Hyatt AD, Eaton BT (eds) (1993) Immune-gold electron microscopy in virus diagnosis and research, CRC Press. Boca Raton, pp 178–454
14.
go back to reference Hayat MA (1989) (ed) Colloidal gold: principles, methods and applications. Academic Press, San Diego Hayat MA (1989) (ed) Colloidal gold: principles, methods and applications. Academic Press, San Diego
15.
go back to reference Alivisatos AP (1996) Perspectives on physical chemistry of semiconductor nanocrystals. J Phys Chem 100:13226–13239 Alivisatos AP (1996) Perspectives on physical chemistry of semiconductor nanocrystals. J Phys Chem 100:13226–13239
16.
go back to reference Chan WCW, Nie S (1998) Quantum dot bioconjugates for ultra sensitive non isotopic detection. Sci 281:2016–2018 Chan WCW, Nie S (1998) Quantum dot bioconjugates for ultra sensitive non isotopic detection. Sci 281:2016–2018
17.
go back to reference Mckenzie KJ, Marken F (2003) Accumulation and reactivity of the redox protein cytochrome in mesoporous films of TiO2 phytate. Langmuir 19:4327–4331 Mckenzie KJ, Marken F (2003) Accumulation and reactivity of the redox protein cytochrome in mesoporous films of TiO2 phytate. Langmuir 19:4327–4331
18.
go back to reference Haruta M (1997) Size- and Support-dependency in catalysis of gold. Catal Today 36:153–166 Haruta M (1997) Size- and Support-dependency in catalysis of gold. Catal Today 36:153–166
19.
go back to reference Haruta M, Yamada N, Kobayashi T et al (1989) Gold catalysts prepared by coprecipitation for low-temperature oxidation of hydrogen and of carbon monoxide. J Catal 115:301–309 Haruta M, Yamada N, Kobayashi T et al (1989) Gold catalysts prepared by coprecipitation for low-temperature oxidation of hydrogen and of carbon monoxide. J Catal 115:301–309
20.
go back to reference Haruta M, Tsubota S, Kobayashi T et al (1993) Low-temperature oxidation of CO over gold supported on TiO2, α-Fe2O3, and Co3O4. J Catal 144:175–192 Haruta M, Tsubota S, Kobayashi T et al (1993) Low-temperature oxidation of CO over gold supported on TiO2, α-Fe2O3, and Co3O4. J Catal 144:175–192
21.
go back to reference Wang J, Koel BE (1998) IRAS studies of NO2, N2O3, and N2O4 adsorbed on Au(111) surfaces and reactions with co-adsorbed H2O. J Phys Chem A 102:8573–8579 Wang J, Koel BE (1998) IRAS studies of NO2, N2O3, and N2O4 adsorbed on Au(111) surfaces and reactions with co-adsorbed H2O. J Phys Chem A 102:8573–8579
22.
go back to reference Okumura M, Tanaka K, Ueda A et al (1997) The reactivities of Dimethylgold(III)Beta-Diketone on the Surface of TiO2–a novel preparation method for Au catalysts. Solid State Ion 95:143–149 Okumura M, Tanaka K, Ueda A et al (1997) The reactivities of Dimethylgold(III)Beta-Diketone on the Surface of TiO2–a novel preparation method for Au catalysts. Solid State Ion 95:143–149
23.
go back to reference Wei Z, Xin Q, Guo X et al (1990) Titanaia-modified hydrodesulphurization catalysts I : effect of preparation techniques on morphology and properties of TiO2-Al2O3 Carrier. Appl Catal A 63:305–309 Wei Z, Xin Q, Guo X et al (1990) Titanaia-modified hydrodesulphurization catalysts I : effect of preparation techniques on morphology and properties of TiO2-Al2O3 Carrier. Appl Catal A 63:305–309
24.
go back to reference Weibel A, Bouchet R, Knauth P (2006) Electrical properties and defect chemistry of anatase (TiO2). Solid State Ion 177:229–236 Weibel A, Bouchet R, Knauth P (2006) Electrical properties and defect chemistry of anatase (TiO2). Solid State Ion 177:229–236
25.
go back to reference Pajonk GM (1991) Aerogel catalysts. Appl Catal 72:217–266 Pajonk GM (1991) Aerogel catalysts. Appl Catal 72:217–266
26.
go back to reference Reluert J, Quijada R, Arias V (1998) Porous titania obtained through polymer incorporated composites. Chem Mater 10:3923–3927 Reluert J, Quijada R, Arias V (1998) Porous titania obtained through polymer incorporated composites. Chem Mater 10:3923–3927
27.
go back to reference Fox MA, Dulay MT (1993) Heterogeneous photocatalysis. Chem Rev 93:341–357 Fox MA, Dulay MT (1993) Heterogeneous photocatalysis. Chem Rev 93:341–357
28.
go back to reference Sopyan I, Murasawa S, Hashimoto S et al (1998) Highly efficient TiO2 film photocatalyst: degradation of gaseous acetaldehyde. Chem Lett 10:723–726 Sopyan I, Murasawa S, Hashimoto S et al (1998) Highly efficient TiO2 film photocatalyst: degradation of gaseous acetaldehyde. Chem Lett 10:723–726
29.
go back to reference Zhang Z, Wang C–C, Zakaria R et al (1998) Role of particle size in nanocrystalline TiO2-based photocatalysts. J Phys Chem B 102:10871–10878 Zhang Z, Wang C–C, Zakaria R et al (1998) Role of particle size in nanocrystalline TiO2-based photocatalysts. J Phys Chem B 102:10871–10878
30.
go back to reference Wang C–C, Ying JY (1999) Sol-Gel Synthesis and hydrothermal processing of anatase and rutile titania nanocrystals. Chem Mater 11:3113–3120 Wang C–C, Ying JY (1999) Sol-Gel Synthesis and hydrothermal processing of anatase and rutile titania nanocrystals. Chem Mater 11:3113–3120
31.
go back to reference Huang W, Tang X, Wang Y et al (2000) Selective synthesis of anatase and rutile via ultrasound irradiation. Chem Commun 15:1415–1416 Huang W, Tang X, Wang Y et al (2000) Selective synthesis of anatase and rutile via ultrasound irradiation. Chem Commun 15:1415–1416
32.
go back to reference Liu H, Yang W, Ma Y et al (2002) Promoted phase transition of titania nanoparticles prepared by a photo-assisted sol-gel method. New J Chem 26:975 Liu H, Yang W, Ma Y et al (2002) Promoted phase transition of titania nanoparticles prepared by a photo-assisted sol-gel method. New J Chem 26:975
33.
go back to reference Hoyer P (1996) Formation of a titanium dioxide nanotu be array. Langmuir 12:1411–1413 Hoyer P (1996) Formation of a titanium dioxide nanotu be array. Langmuir 12:1411–1413
34.
go back to reference Liu SM, Gan LM, Liu LH et al (2002) Synthesis of single-crystalline TiO2 nanotubes. Chem Mater 14:1391–1397 Liu SM, Gan LM, Liu LH et al (2002) Synthesis of single-crystalline TiO2 nanotubes. Chem Mater 14:1391–1397
35.
go back to reference Wang YQ, Hu GQ, Duan XF et al. (2002) Microstructure and formation mechanism of titanium dioxide nanotubes. Chem Phys Lett 365:427–431 Wang YQ, Hu GQ, Duan XF et al. (2002) Microstructure and formation mechanism of titanium dioxide nanotubes. Chem Phys Lett 365:427–431
36.
go back to reference Ivanovskaya VV, Enyashin AN, Ivanovskii AL (2003) Electronic structure of single-walled TiO2 and VO2 nanotubes. Mendeleev Commun 13:5–7 Ivanovskaya VV, Enyashin AN, Ivanovskii AL (2003) Electronic structure of single-walled TiO2 and VO2 nanotubes. Mendeleev Commun 13:5–7
37.
go back to reference Kasuga T, Hiramatu M, Hirano M et al (1997) Synthesis and functionalization titania nanotube. Mater Res 12:607–609 Kasuga T, Hiramatu M, Hirano M et al (1997) Synthesis and functionalization titania nanotube. Mater Res 12:607–609
38.
go back to reference Jung JH, Kobayashi H, van Bommel KJC et al (2002) Creation of novel helical ribbon and double-layered nanotube TiO2 structures using an organogel template. Chem Mater 14:1445–1447 Jung JH, Kobayashi H, van Bommel KJC et al (2002) Creation of novel helical ribbon and double-layered nanotube TiO2 structures using an organogel template. Chem Mater 14:1445–1447
39.
go back to reference Imai H, Takei Y, Shimizu K et al (1999) Direct preparation of anatase TiO2 nanotubes in porous alumina membranes. J Mater Chem 9:2971–2972 Imai H, Takei Y, Shimizu K et al (1999) Direct preparation of anatase TiO2 nanotubes in porous alumina membranes. J Mater Chem 9:2971–2972
40.
go back to reference Dignam MJ, Moskovits M (1973) Influence of surface roughness on the transmission and reflectance spectra of adsorbed species. J Chem Soc, Faraday Trans 2(69):95–78 Dignam MJ, Moskovits M (1973) Influence of surface roughness on the transmission and reflectance spectra of adsorbed species. J Chem Soc, Faraday Trans 2(69):95–78
41.
go back to reference Mahata N, Raghavan KV, Vishwanathan V et al (2001) Phenol hydrogenation over palladium supported on magnesia: relationship between catalyst structure and performance. Phys Chem Chem Phys 3:2712–2719 Mahata N, Raghavan KV, Vishwanathan V et al (2001) Phenol hydrogenation over palladium supported on magnesia: relationship between catalyst structure and performance. Phys Chem Chem Phys 3:2712–2719
42.
go back to reference Mahmood FS, Gould RD, Salih MH (1995) D.C. properties of ZnO thin films prepared by r.f. magnetron sputtering. Thin Solid Films 270:376–379 Mahmood FS, Gould RD, Salih MH (1995) D.C. properties of ZnO thin films prepared by r.f. magnetron sputtering. Thin Solid Films 270:376–379
43.
go back to reference Gorla CR, Emanetoglu NW, Liang S et al (1999) Structural, optical, and surface acoustic wave properties of epitaxial ZnO films grown on (0112) sapphire by metalorganic chemical vapor deposition. J Appl Phys 85:2595–2602 Gorla CR, Emanetoglu NW, Liang S et al (1999) Structural, optical, and surface acoustic wave properties of epitaxial ZnO films grown on (0112) sapphire by metalorganic chemical vapor deposition. J Appl Phys 85:2595–2602
44.
go back to reference Look DC (2001) Recent advances in ZnO materials and devices. Mater Sci Eng, B 80:383–387 Look DC (2001) Recent advances in ZnO materials and devices. Mater Sci Eng, B 80:383–387
45.
go back to reference Hvam JM (1973) Exciton-exciton interaction and laser emission in high-purity ZnO. Solid State Commun 12:95–97 Hvam JM (1973) Exciton-exciton interaction and laser emission in high-purity ZnO. Solid State Commun 12:95–97
46.
go back to reference Klingshirn C (1975) Room-temperature stimulated emission of ZnO: alternatives to excitonic lasing. Phys Status Solidi B 71:547–556 Klingshirn C (1975) Room-temperature stimulated emission of ZnO: alternatives to excitonic lasing. Phys Status Solidi B 71:547–556
47.
go back to reference Caillaud FA, Smith A, Baumard JM (1992) Additives content in ZnO films prepared by spray pyrolysis. J Eur Ceram Soc 9:447–452 Caillaud FA, Smith A, Baumard JM (1992) Additives content in ZnO films prepared by spray pyrolysis. J Eur Ceram Soc 9:447–452
48.
go back to reference Musić S, Dragčević D, Malijković M et al (2003) Influence of chemical synthesis on the crystallization and properties of zinc oxide. Mater Chem Phys 77:521–530 Musić S, Dragčević D, Malijković M et al (2003) Influence of chemical synthesis on the crystallization and properties of zinc oxide. Mater Chem Phys 77:521–530
49.
go back to reference Wang X, Li Y (2002) Selected-control hydrothermal synthesis of α- and β-MnO2 single crystal nanowires. J Am Chem Soc 124:2880–2881 Wang X, Li Y (2002) Selected-control hydrothermal synthesis of α- and β-MnO2 single crystal nanowires. J Am Chem Soc 124:2880–2881
50.
go back to reference Chu D, Zeng Y, Jiang D (2007) Controlled growth and properties of Pb2+ doped ZnO nanodisks. Mater Res Bull 42:814–819 Chu D, Zeng Y, Jiang D (2007) Controlled growth and properties of Pb2+ doped ZnO nanodisks. Mater Res Bull 42:814–819
51.
go back to reference Sun Y, Xia Y (2002) Shape-controlled synthesis of gold and silver nanoparticles. Science 298:2176–2179 Sun Y, Xia Y (2002) Shape-controlled synthesis of gold and silver nanoparticles. Science 298:2176–2179
52.
go back to reference Kirk-Othmer (1993) Encyclopedia of chemical technology***, vol 5. Wiley, Canada Kirk-Othmer (1993) Encyclopedia of chemical technology***, vol 5. Wiley, Canada
53.
go back to reference Christoffel EG (1989) Laboratory studies of heterogeneous catalytic processes. Elsevier, Oxford Christoffel EG (1989) Laboratory studies of heterogeneous catalytic processes. Elsevier, Oxford
54.
go back to reference Corma A (1995) Inorganic solid acids and their use in acid-catalyzed hydrocarbon reactions. Chem Rev 95:559–614 Corma A (1995) Inorganic solid acids and their use in acid-catalyzed hydrocarbon reactions. Chem Rev 95:559–614
55.
go back to reference Ardizzone S, Bianchi CL, Ragaini V et al (1999) SO4-ZrO2 catalysts for the esterification of benzoic to methylbenzoate. Catal Lett 62:59–65 Ardizzone S, Bianchi CL, Ragaini V et al (1999) SO4-ZrO2 catalysts for the esterification of benzoic to methylbenzoate. Catal Lett 62:59–65
56.
go back to reference Salamanca-Buentello F, Persad DL, Court EB et al (2005) Nanotechnology and the developing world. PLoS Med 2:383–386 Salamanca-Buentello F, Persad DL, Court EB et al (2005) Nanotechnology and the developing world. PLoS Med 2:383–386
57.
go back to reference UNEP (2007) UNEP Emerging Challenges—Nanotechnology and the Environment, Geo Yearbook 2007. Nairobi, Kenya, UNEP UNEP (2007) UNEP Emerging Challenges—Nanotechnology and the Environment, Geo Yearbook 2007. Nairobi, Kenya, UNEP
58.
go back to reference Montgomery MA, Elimelech M (2007) Water and sanitation in developing countries: including health in the equation. Environ Sci Technol 41:17–24 Montgomery MA, Elimelech M (2007) Water and sanitation in developing countries: including health in the equation. Environ Sci Technol 41:17–24
59.
go back to reference Eshelby K (2007) Dying for a drink. BMJ 334:610–612 Eshelby K (2007) Dying for a drink. BMJ 334:610–612
61.
go back to reference DST (2005) National nanotechnology strategy. Department of Science and Technology, Pretoria DST (2005) National nanotechnology strategy. Department of Science and Technology, Pretoria
62.
go back to reference DST (2010) Nanoscience and nanotechnology 10-year research plan. Department of Science and Technology, Pretoria DST (2010) Nanoscience and nanotechnology 10-year research plan. Department of Science and Technology, Pretoria
63.
go back to reference Hillie T, Hlophe M (2007) Nanotechnology and the challenge of clean water. Nat Nanotechnol 2:663–664 Hillie T, Hlophe M (2007) Nanotechnology and the challenge of clean water. Nat Nanotechnol 2:663–664
64.
go back to reference Hillie T, Munasinghe M, Hlope M et al. (2006) Nanotechnology, water and development, Paper commissioned as part of the Global Dialogue on Nanotechnology and the poor: opportunities and risks, Meridian Institute’s, Web link: http://www.merid.org/nano/waterpaper Hillie T, Munasinghe M, Hlope M et al. (2006) Nanotechnology, water and development, Paper commissioned as part of the Global Dialogue on Nanotechnology and the poor: opportunities and risks, Meridian Institute’s, Web link: http://​www.​merid.​org/​nano/​waterpaper
65.
go back to reference Theron J, Walker JA, Cloete TE (2008) Nanotechnology and water treatment: applications and emerging opportunities. Crit Rev Microbiol 34:43–69 Theron J, Walker JA, Cloete TE (2008) Nanotechnology and water treatment: applications and emerging opportunities. Crit Rev Microbiol 34:43–69
66.
go back to reference Baker RW (2004) Membrane technology and applications. Wiley, England Baker RW (2004) Membrane technology and applications. Wiley, England
67.
go back to reference Srivastava AK, Srivastava ON, Talapatra S et al (2004) Carbon nanotube filters. Nat Mat 3:610–614 Srivastava AK, Srivastava ON, Talapatra S et al (2004) Carbon nanotube filters. Nat Mat 3:610–614
68.
go back to reference Tully DC, Frechet JMJ (2001) Dendrimers at surfaces and interfaces: chemistry and applications. J Chem Commun 14:1229–1239 Tully DC, Frechet JMJ (2001) Dendrimers at surfaces and interfaces: chemistry and applications. J Chem Commun 14:1229–1239
69.
go back to reference Gao C, Yan D (2004) Hyperbranched polymers: from synthesis to applications. Prog Polym Sci 29:183–275 Gao C, Yan D (2004) Hyperbranched polymers: from synthesis to applications. Prog Polym Sci 29:183–275
70.
go back to reference Del Valle EMM (2004) Cyclodextrins and their uses, A review. Process Biochem 39:1033–1046 Del Valle EMM (2004) Cyclodextrins and their uses, A review. Process Biochem 39:1033–1046
71.
go back to reference Mamba BB, Krause RW, Malefetse TJ et al (2007) Monofunctionalized cyclodextrin polymers for the removal of organic pollutants from water. Environ Chem Lett 5:79–84 Mamba BB, Krause RW, Malefetse TJ et al (2007) Monofunctionalized cyclodextrin polymers for the removal of organic pollutants from water. Environ Chem Lett 5:79–84
72.
go back to reference Salipira KL, Mamba BB, Krause RW et al (2008) Cyclodextrin polyurethanes polymerised with carbon nanotubes for the removal of organic pollutants in water. Water SA 34:113–118 Salipira KL, Mamba BB, Krause RW et al (2008) Cyclodextrin polyurethanes polymerised with carbon nanotubes for the removal of organic pollutants in water. Water SA 34:113–118
73.
go back to reference Sawicki R, Mercier L (2006) Evaluation of mesoporous cyclodextrin-silica nanocomposites for the removal of pesticides from aqueous media. Environ Sci Technol 40:1978–1983 Sawicki R, Mercier L (2006) Evaluation of mesoporous cyclodextrin-silica nanocomposites for the removal of pesticides from aqueous media. Environ Sci Technol 40:1978–1983
74.
go back to reference Arkas M, Allabashi R, Tsiourvas D et al (2006) Organic/inorganic hybrid filters based on dendritic and cyclodextrin “nanosponges” for the removal of organic pollutants from water. Environ Sci Technol 40:2771–2777 Arkas M, Allabashi R, Tsiourvas D et al (2006) Organic/inorganic hybrid filters based on dendritic and cyclodextrin “nanosponges” for the removal of organic pollutants from water. Environ Sci Technol 40:2771–2777
75.
go back to reference Nair AS, Pradeep T (2003) Halocarbon mineralization and catalytic destruction by metal nanoparticles. Curr Sci 84:1560–1564 Nair AS, Pradeep T (2003) Halocarbon mineralization and catalytic destruction by metal nanoparticles. Curr Sci 84:1560–1564
76.
go back to reference Predeep TA, Anshup (2009) Nobel metal nanoparticles for water purification: a critical review. Thin Solid Films 517:6441–6478 Predeep TA, Anshup (2009) Nobel metal nanoparticles for water purification: a critical review. Thin Solid Films 517:6441–6478
77.
go back to reference Pradeep TA (2009) In: Savage N, Diallo M, Duncan J, Street A, Sustich R (eds) Nanotechnology applications for clean water. William Andrew Publication, USA, p 2009 Pradeep TA (2009) In: Savage N, Diallo M, Duncan J, Street A, Sustich R (eds) Nanotechnology applications for clean water. William Andrew Publication, USA, p 2009
78.
go back to reference Schwarzenbach RP, Escher BI, Fenner K et al (2006) The challenge of micropollutants in aquatic systems. Sci 313:1072–1077 Schwarzenbach RP, Escher BI, Fenner K et al (2006) The challenge of micropollutants in aquatic systems. Sci 313:1072–1077
79.
go back to reference Ahluwalia SS, Goyal D (2007) Microbial and plant derived biomass for removal of heavy metals from wastewater. Bioresour Technol 98:2243–2257 Ahluwalia SS, Goyal D (2007) Microbial and plant derived biomass for removal of heavy metals from wastewater. Bioresour Technol 98:2243–2257
80.
go back to reference Savage N, Diallo MS (2005) Nanomaterials and water purification: opportunities and challenges. J Nanopart Res 7:331–342 Savage N, Diallo MS (2005) Nanomaterials and water purification: opportunities and challenges. J Nanopart Res 7:331–342
81.
go back to reference Tratnyek PG, Johnson RL (2006) Nanotechnologies for environmental cleanup. Nanotoday 1:44–48 Tratnyek PG, Johnson RL (2006) Nanotechnologies for environmental cleanup. Nanotoday 1:44–48
82.
go back to reference Li Q, Mahendra S, Lyon DY et al (2008) Antimicrobial nanomaterials for water disinfection and microbial control: potential applications and implications. Water Res 42:4591–4602 Li Q, Mahendra S, Lyon DY et al (2008) Antimicrobial nanomaterials for water disinfection and microbial control: potential applications and implications. Water Res 42:4591–4602
83.
go back to reference Wang CB, Zhang WX (1997) Synthesizing nanoscale iron particles for rapid and complete dechlorination of TCE and PCBs. Environ Sci Technol 31:2154–2156 Wang CB, Zhang WX (1997) Synthesizing nanoscale iron particles for rapid and complete dechlorination of TCE and PCBs. Environ Sci Technol 31:2154–2156
84.
go back to reference Liou YH, Lo SL, Kuan WH et al (2006) Effect of precursor concentration on the characterics of nanoscale zerovalent iron and its reactivity with nitrate. Wat Res 40:2485–2492 Liou YH, Lo SL, Kuan WH et al (2006) Effect of precursor concentration on the characterics of nanoscale zerovalent iron and its reactivity with nitrate. Wat Res 40:2485–2492
85.
go back to reference Sohn K, Kang SW, Ahn S et al (2006) Fe(0) nanoparticles for nitrate reduction: stability, reactivity, and transformation. Environ Sci Technol 40:5514–5519 Sohn K, Kang SW, Ahn S et al (2006) Fe(0) nanoparticles for nitrate reduction: stability, reactivity, and transformation. Environ Sci Technol 40:5514–5519
86.
go back to reference Cao J, Elliott D, Zhang WX (2005) Perchlorate reduction by nanoscale iron particles. J Nanopart Res 7:499–506 Cao J, Elliott D, Zhang WX (2005) Perchlorate reduction by nanoscale iron particles. J Nanopart Res 7:499–506
87.
go back to reference Ponder SM, Darab JG, Mallouk TE (2000) Remediation of Cr(VI) and Pb(II) aqueous solutions using supported, nanoscale zero-valent iron. Environ Sci Technol 34:2564–2569 Ponder SM, Darab JG, Mallouk TE (2000) Remediation of Cr(VI) and Pb(II) aqueous solutions using supported, nanoscale zero-valent iron. Environ Sci Technol 34:2564–2569
88.
go back to reference Kanel SR, Manning B, Charlet L et al (2005) Removal of arsenic (III) from groundwater by nanoscale zero-valent iron. Environ Sci Technol 39:1291–1298 Kanel SR, Manning B, Charlet L et al (2005) Removal of arsenic (III) from groundwater by nanoscale zero-valent iron. Environ Sci Technol 39:1291–1298
89.
go back to reference Li XQ, Zhang WX (2006) Iron nanoparticles, the core–shell structure and unique properties for Ni (II) sequestration. Langmuir 22:4638–4642 Li XQ, Zhang WX (2006) Iron nanoparticles, the core–shell structure and unique properties for Ni (II) sequestration. Langmuir 22:4638–4642
90.
go back to reference Keum YS, Li QX (2004) Reduction of nitroaromatic pesticides with zerovalent iron. Chemosphere 54:255–263 Keum YS, Li QX (2004) Reduction of nitroaromatic pesticides with zerovalent iron. Chemosphere 54:255–263
91.
go back to reference Zhang L, Fang M (2010) Nanomaterials in pollution trace detection and environmental improvement. Nano Today 5:128–142 Zhang L, Fang M (2010) Nanomaterials in pollution trace detection and environmental improvement. Nano Today 5:128–142
92.
go back to reference Elliot DW, Zhang WX (2001) Field assessment of nanoscale biometallic particles for ground water treatment. Environ Sci Technol 35:4922–4926 Elliot DW, Zhang WX (2001) Field assessment of nanoscale biometallic particles for ground water treatment. Environ Sci Technol 35:4922–4926
93.
go back to reference He P, Zhao DY (2005) Preparation and characterization of a new class of starch–stabilized bimetallic nanoparticles for degradation of chlorinated hydrocarbons in water. Environ Sci Technol 39:3314–3320 He P, Zhao DY (2005) Preparation and characterization of a new class of starch–stabilized bimetallic nanoparticles for degradation of chlorinated hydrocarbons in water. Environ Sci Technol 39:3314–3320
94.
go back to reference Schrick B, Hydutsky BW, Blough JL, Mallouk TE (2004) Delivery vehicles for zerovalent metal nanoparticles in soil and groundwater. Chem Mater 16:2187–2193 Schrick B, Hydutsky BW, Blough JL, Mallouk TE (2004) Delivery vehicles for zerovalent metal nanoparticles in soil and groundwater. Chem Mater 16:2187–2193
95.
go back to reference He F, Zhao DY, Liu J et al (2007) Stabilization of Fe-Pd nanoparticles with sodium carboxymethyl cellulose for enhanced transport and dechlorination of trichloroethylene in soil and groundwater. Ind Eng Chem Res 46:29–34 He F, Zhao DY, Liu J et al (2007) Stabilization of Fe-Pd nanoparticles with sodium carboxymethyl cellulose for enhanced transport and dechlorination of trichloroethylene in soil and groundwater. Ind Eng Chem Res 46:29–34
96.
go back to reference Saleh N, Sirk K, Liu YQ et al (2007) Surface modifications enhance nano iron transport and NAPL targeting in satulated porous media. Envrion Eng Sci 24:45–57 Saleh N, Sirk K, Liu YQ et al (2007) Surface modifications enhance nano iron transport and NAPL targeting in satulated porous media. Envrion Eng Sci 24:45–57
97.
go back to reference Kikuchi Y, Sunada K, Iyoda T et al (1997) Photocatalytic bactericidal effect of TiO2 thin films: dynamic view of the active oxygen species responsible for the effect. J Photochem Photobiol A Chem 106:51–56 Kikuchi Y, Sunada K, Iyoda T et al (1997) Photocatalytic bactericidal effect of TiO2 thin films: dynamic view of the active oxygen species responsible for the effect. J Photochem Photobiol A Chem 106:51–56
98.
go back to reference Choi H, Stathatos E, Dionysiou D (2007) Photocatalytic TiO2 films and membranes for the development of efficient wastewater treatment and reuse systems. Desalination 202:199–206 Choi H, Stathatos E, Dionysiou D (2007) Photocatalytic TiO2 films and membranes for the development of efficient wastewater treatment and reuse systems. Desalination 202:199–206
99.
go back to reference Hoff JC (1986) Inactivation of microbial agents by chemical disinfectants. EPA/600/S602-686/067. U.S. Environmental Protection Agency, Cincinnati, OH Hoff JC (1986) Inactivation of microbial agents by chemical disinfectants. EPA/600/S602-686/067. U.S. Environmental Protection Agency, Cincinnati, OH
100.
go back to reference Hunt NK, Marinas BJ (1997) Kinetics of Escherichia Coli inactivation with ozone. Wat Res 31(6):1355–1362 Hunt NK, Marinas BJ (1997) Kinetics of Escherichia Coli inactivation with ozone. Wat Res 31(6):1355–1362
101.
go back to reference Morones JR, Elechiguerra JL, Camacho A et al (2005) The bactericidal effect of silver nanoparticles. Nanotechnol 16:2346–2353 Morones JR, Elechiguerra JL, Camacho A et al (2005) The bactericidal effect of silver nanoparticles. Nanotechnol 16:2346–2353
102.
go back to reference Pal S, Tak YK, Song JM (2007) Does the antibacterial activity of silver nanoparticles depend on the shape of the nanoparticle? A study of the Gram—negative bacterium Escherichia coli. Appl Environ Microbiol 73:1712–1720 Pal S, Tak YK, Song JM (2007) Does the antibacterial activity of silver nanoparticles depend on the shape of the nanoparticle? A study of the Gram—negative bacterium Escherichia coli. Appl Environ Microbiol 73:1712–1720
103.
go back to reference Sondi I, Salopek-Sondi B (2004) Silver nanoparticles as antimicrobial agent: case study on E. coli as a model for Gram-negative bacteria. J Colloid Interface Sci 275:177–182 Sondi I, Salopek-Sondi B (2004) Silver nanoparticles as antimicrobial agent: case study on E. coli as a model for Gram-negative bacteria. J Colloid Interface Sci 275:177–182
104.
go back to reference Kim JS, Kuk E, Yu KM et al (2007) Antimicrobial effects of silver nanoparticles. Nanomedicine 3:95–101 Kim JS, Kuk E, Yu KM et al (2007) Antimicrobial effects of silver nanoparticles. Nanomedicine 3:95–101
105.
go back to reference Shahverdi AR, Kakhimi A, Shahverdi HD, Minaian S (2007) Synthesis and effect of silver nanoparticles on the antibacterial activity of different antibiotics against Staphylococcus aureus and Escherichia coli. Nanomed Nanotechnol Biol Med 3:168–171 Shahverdi AR, Kakhimi A, Shahverdi HD, Minaian S (2007) Synthesis and effect of silver nanoparticles on the antibacterial activity of different antibiotics against Staphylococcus aureus and Escherichia coli. Nanomed Nanotechnol Biol Med 3:168–171
107.
go back to reference Yoon KY, Byeon JH, Park JH et al (2007) Susceptibility constants of Escherichia coli and Bacillus subtilis to silver and copper nanoparticles. Sci Total Environ 373:572–575 Yoon KY, Byeon JH, Park JH et al (2007) Susceptibility constants of Escherichia coli and Bacillus subtilis to silver and copper nanoparticles. Sci Total Environ 373:572–575
108.
go back to reference Ju-Nam Y, Lead JR (2008) Manufactured nanoparticles: an overview of their chemistry, interactions and potential environmental implications. Sci Total Environ 400:396–414 Ju-Nam Y, Lead JR (2008) Manufactured nanoparticles: an overview of their chemistry, interactions and potential environmental implications. Sci Total Environ 400:396–414
109.
go back to reference Danilczuk M, Lund A, Saldo J et al (2006) Conduction electron spin resonance of small silver particles. Spectrochim Acta A 63:189–191 Danilczuk M, Lund A, Saldo J et al (2006) Conduction electron spin resonance of small silver particles. Spectrochim Acta A 63:189–191
110.
go back to reference Mills A, LeHunte S (1997) An overview of semiconductor photocatalysis. J Photochem Photobiol A Chem 108:1–35 Mills A, LeHunte S (1997) An overview of semiconductor photocatalysis. J Photochem Photobiol A Chem 108:1–35
111.
go back to reference Lee S, Nakamura M, Ohgaki S (1998) Inactivation of phage Qβ by 254 nm UV light and titanium dioxide photocatalyst. J Environ Sci Health A 33:1643–1655 Lee S, Nakamura M, Ohgaki S (1998) Inactivation of phage Qβ by 254 nm UV light and titanium dioxide photocatalyst. J Environ Sci Health A 33:1643–1655
112.
go back to reference Inaba R, Fukahori T, Hamamoto M et al (2006) Synthesis of nanosized TiO2 particles in reverse micelle systems and their photocalytic activity for degradation of toluene in gas phase. J Mol Cat A: Chem 200:247–254 Inaba R, Fukahori T, Hamamoto M et al (2006) Synthesis of nanosized TiO2 particles in reverse micelle systems and their photocalytic activity for degradation of toluene in gas phase. J Mol Cat A: Chem 200:247–254
113.
go back to reference Shephard GS, Stockenstrom S, de Villiers D et al (2002) Degradation of microcystin toxins in a falling film photocatalytic reactor with immobilized titanium dioxide catalyst. Water Res 36:140–146 Shephard GS, Stockenstrom S, de Villiers D et al (2002) Degradation of microcystin toxins in a falling film photocatalytic reactor with immobilized titanium dioxide catalyst. Water Res 36:140–146
114.
go back to reference Kominami H, Murakami S, Kato J et al (2002) Correlation between some physical properties of titanium dioxide particles and their photocatalytic activity for some probe reactions in aqueous systems. J Phys Chem B 106:10501–10507 Kominami H, Murakami S, Kato J et al (2002) Correlation between some physical properties of titanium dioxide particles and their photocatalytic activity for some probe reactions in aqueous systems. J Phys Chem B 106:10501–10507
115.
go back to reference Toma D, Bertrand G, Chwa SO et al. (2006) Comparative study on the photocatalytic decomposition of nitrogen oxides using TiO2 coatings prepared by conventional plasma spraying and suspension plasma spraying. Surf Coat Technol 200:5855–5862). Toma D, Bertrand G, Chwa SO et al. (2006) Comparative study on the photocatalytic decomposition of nitrogen oxides using TiO2 coatings prepared by conventional plasma spraying and suspension plasma spraying. Surf Coat Technol 200:5855–5862).
116.
go back to reference Joo J, Kwon SG, Yu T et al (2005) Large– scale synthesis of TiO2 nanorods via nonhydrolytic sol-gel ester elimination reaction and their application to photocatalytic inactivation of E. coli. J Phys Chem B 109:15297–15302 Joo J, Kwon SG, Yu T et al (2005) Large– scale synthesis of TiO2 nanorods via nonhydrolytic sol-gel ester elimination reaction and their application to photocatalytic inactivation of E. coli. J Phys Chem B 109:15297–15302
117.
go back to reference Egerton TA, Kosa SA, Christensen PA (2006) Photoelectrocatalytic disinfection of E. coli suspensions by iron doped TiO2. Phys Chem Chem Phys 8:398–406 Egerton TA, Kosa SA, Christensen PA (2006) Photoelectrocatalytic disinfection of E. coli suspensions by iron doped TiO2. Phys Chem Chem Phys 8:398–406
118.
go back to reference Page K, Palgrave RG, Parkin IP et al (2007) Titania and silver-titania composite films on glass-potent antimicrobial coatings. J Mat Chem 17(1):95–104 Page K, Palgrave RG, Parkin IP et al (2007) Titania and silver-titania composite films on glass-potent antimicrobial coatings. J Mat Chem 17(1):95–104
119.
go back to reference Yu JC, Yu J, Zhao J (2002) Enhanced photocatalytic activity of mesoporous and ordinary TiO2 thin films by sulfuric acid treatment. Appl Catal B Environ 36:31–43 Yu JC, Yu J, Zhao J (2002) Enhanced photocatalytic activity of mesoporous and ordinary TiO2 thin films by sulfuric acid treatment. Appl Catal B Environ 36:31–43
120.
go back to reference das Neves J, Amiji MM, Bahia MF et al (2010) Nanotechnology-based systems for the treatment and prevention of HIV/AIDS. Adv Drug Deliv Rev 62:458–477 das Neves J, Amiji MM, Bahia MF et al (2010) Nanotechnology-based systems for the treatment and prevention of HIV/AIDS. Adv Drug Deliv Rev 62:458–477
121.
go back to reference Gunaseelan S, Gunaseelan K, Deshmukh M et al (2010) Surface modifications of nanocarriers for effective intracellular delivery of anti-HIV drugs. Adv Drug Deliv Rev 62:518–531 Gunaseelan S, Gunaseelan K, Deshmukh M et al (2010) Surface modifications of nanocarriers for effective intracellular delivery of anti-HIV drugs. Adv Drug Deliv Rev 62:518–531
122.
go back to reference Gupta U, Jain NK (2010) Non-polymeric nano-carriers in HIV/AIDS drug delivery and targeting. Adv Drug Deliv Rev 62:478–490 Gupta U, Jain NK (2010) Non-polymeric nano-carriers in HIV/AIDS drug delivery and targeting. Adv Drug Deliv Rev 62:478–490
123.
go back to reference Sharma P, Garg S (2010) Pure drug and polymer based nanotechnologies for the improved solubility, stability, bioavailability and targeting of anti-HIV drugs. Adv Drug Del Rev 62:491–502 Sharma P, Garg S (2010) Pure drug and polymer based nanotechnologies for the improved solubility, stability, bioavailability and targeting of anti-HIV drugs. Adv Drug Del Rev 62:491–502
124.
go back to reference Wong HL, Chattopadhyay N, Wu XY et al (2010) Nanotechnology applications for improved delivery of antiretroviral drugs to the brain. Adv Drug Deliv Rev 62:503–517 Wong HL, Chattopadhyay N, Wu XY et al (2010) Nanotechnology applications for improved delivery of antiretroviral drugs to the brain. Adv Drug Deliv Rev 62:503–517
125.
go back to reference du Toit LC, Pillay V, Choonara YE (2010) Nano-microbicides: challenges in drug delivery, patient ethics and intellectual property in the war against HIV/AIDS. Adv Drug Del Rev 62:532–546 du Toit LC, Pillay V, Choonara YE (2010) Nano-microbicides: challenges in drug delivery, patient ethics and intellectual property in the war against HIV/AIDS. Adv Drug Del Rev 62:532–546
126.
go back to reference Hammer SM, Eron JJ Jr, Reiss P et al (2008) International AIDS Society-USA, antiretroviral treatment of adult HIV infection: 2008 recommendations of the International AIDS Society-USA panel. JAMA 300:555–570 Hammer SM, Eron JJ Jr, Reiss P et al (2008) International AIDS Society-USA, antiretroviral treatment of adult HIV infection: 2008 recommendations of the International AIDS Society-USA panel. JAMA 300:555–570
127.
go back to reference Blankson JN, Persaud D, Siliciano RF (2002) The challenge of viral reservoirs in HIV-1 infection. Ann Rev Med 53:557–593 Blankson JN, Persaud D, Siliciano RF (2002) The challenge of viral reservoirs in HIV-1 infection. Ann Rev Med 53:557–593
128.
go back to reference Amiji MM, Vyas TK, Shah LK (2006) Role of nanotechnology in HIV/AIDS treatment: potential to overcome the viral reservoir challenge. Discov Med 6:157–162 Amiji MM, Vyas TK, Shah LK (2006) Role of nanotechnology in HIV/AIDS treatment: potential to overcome the viral reservoir challenge. Discov Med 6:157–162
129.
go back to reference Chun TW, Justement JS, Moir S et al (2007) Decay of the HIV reservoir in patients receiving antiretroviral therapy for extended periods: implications for eradication of virus. J Infect Dis 195:1762–1764 Chun TW, Justement JS, Moir S et al (2007) Decay of the HIV reservoir in patients receiving antiretroviral therapy for extended periods: implications for eradication of virus. J Infect Dis 195:1762–1764
130.
go back to reference Temesgen Z, Warnke D, Kasten MJ (2006) Current status of antiretroviral therapy. Expert Opin Pharmacother 7:1541–1554 Temesgen Z, Warnke D, Kasten MJ (2006) Current status of antiretroviral therapy. Expert Opin Pharmacother 7:1541–1554
131.
go back to reference Spitzenberger TJ, Heilman D, Diekmann C et al (2007) Novel delivery system enhances efficacy of antiretroviral therapy in animal model for HIV-1 encephalitis. J Cereb Blood Flow Metab 27:1033–1042 Spitzenberger TJ, Heilman D, Diekmann C et al (2007) Novel delivery system enhances efficacy of antiretroviral therapy in animal model for HIV-1 encephalitis. J Cereb Blood Flow Metab 27:1033–1042
132.
go back to reference Govender T, Ojewole E, Naidoo P et al (2008) Polymeric nanoparticles for enhancing antiretroviral drug therapy. Drug Deliv 15:493–501 Govender T, Ojewole E, Naidoo P et al (2008) Polymeric nanoparticles for enhancing antiretroviral drug therapy. Drug Deliv 15:493–501
133.
go back to reference Urdea M, Penny LA, Olmsted SS et al (2006) Requirements for high impact diagnostics in the developing world. Nature 444(Suppl 1):73–79 Urdea M, Penny LA, Olmsted SS et al (2006) Requirements for high impact diagnostics in the developing world. Nature 444(Suppl 1):73–79
134.
go back to reference Yager P, Edwards T, Fu E, Helton K et al (2006) Microfluidic diagnostic technologies for global public health. Nature 442:412–418 Yager P, Edwards T, Fu E, Helton K et al (2006) Microfluidic diagnostic technologies for global public health. Nature 442:412–418
135.
go back to reference Gardella F, Assi S, Simon F et al (2008) Antimalarial drug use in general populations of tropical Africa. Malar J 7:124 Gardella F, Assi S, Simon F et al (2008) Antimalarial drug use in general populations of tropical Africa. Malar J 7:124
136.
go back to reference Greenwood BM, Fidock DA, Kyle DE et al (2008) Malaria: progress, perils, and prospects for eradication. J Clin Invest 118:1266–1276 Greenwood BM, Fidock DA, Kyle DE et al (2008) Malaria: progress, perils, and prospects for eradication. J Clin Invest 118:1266–1276
137.
go back to reference Skinner-Adams TS, McCarthy JS, Gardiner DL et al (2008) HIV and malaria co-infection: interactions and consequences of chemotherapy. Trends Parasitol 24:264–271 Skinner-Adams TS, McCarthy JS, Gardiner DL et al (2008) HIV and malaria co-infection: interactions and consequences of chemotherapy. Trends Parasitol 24:264–271
138.
go back to reference Santos-Magalhães NS, Mosqueira VCF (2010) Nanotechnology applied to the treatment of malaria. Adv Drug Del Rev 62:560–575 Santos-Magalhães NS, Mosqueira VCF (2010) Nanotechnology applied to the treatment of malaria. Adv Drug Del Rev 62:560–575
139.
go back to reference Winstanley P, Ward S (2006) Malaria chemotherapy. Adv Parasitol 61:47–76 Winstanley P, Ward S (2006) Malaria chemotherapy. Adv Parasitol 61:47–76
140.
go back to reference Vauthier C and P. Couvreur P (2007) Nanomedicines: a new approach for the treatment of serious diseases J Biomed Nanotechnol 3:223–234 Vauthier C and P. Couvreur P (2007) Nanomedicines: a new approach for the treatment of serious diseases J Biomed Nanotechnol 3:223–234
141.
go back to reference Forrest ML, Kwon GS (2008) Clinical developments in drug delivery nanotechnology. Adv Drug Deliv Rev 60:861–862 Forrest ML, Kwon GS (2008) Clinical developments in drug delivery nanotechnology. Adv Drug Deliv Rev 60:861–862
142.
go back to reference Foger F, Noonpakdee W, Loretz B et al (2006) Inhibition of malarial topoisomerase II in Plasmodium falciparum by antisense nanoparticles. Int J Pharm 319:139–146 Foger F, Noonpakdee W, Loretz B et al (2006) Inhibition of malarial topoisomerase II in Plasmodium falciparum by antisense nanoparticles. Int J Pharm 319:139–146
143.
go back to reference Barker RH Jr, Metelev V, Coakley A et al (1998) Plasmodium falciparum: effect of chemical structure on efficacy and specificity of antisense oligonucleotides against malaria in vitro. Exp Parasitol 88:51–59 Barker RH Jr, Metelev V, Coakley A et al (1998) Plasmodium falciparum: effect of chemical structure on efficacy and specificity of antisense oligonucleotides against malaria in vitro. Exp Parasitol 88:51–59
144.
go back to reference Noonpakdee W, Pothikasikorn J, Nimitsantiwong W et al (2003) Inhibition of Plasmodium falciparum proliferation in vitro by antisense oligodeoxynucleotides against malarial topoisomerase II. Biochem Biophys Res Commun 302:659–664 Noonpakdee W, Pothikasikorn J, Nimitsantiwong W et al (2003) Inhibition of Plasmodium falciparum proliferation in vitro by antisense oligodeoxynucleotides against malarial topoisomerase II. Biochem Biophys Res Commun 302:659–664
145.
go back to reference Wong HL, Bendayan R, Rauth AM et al (2006) A mechanistic study of enhanced doxorubicin uptake and retention in multidrug resistant breast cancer cells using a polymer-lipid hybrid nanoparticle system. J Pharmacol Exp Ther 317:1372–1381 Wong HL, Bendayan R, Rauth AM et al (2006) A mechanistic study of enhanced doxorubicin uptake and retention in multidrug resistant breast cancer cells using a polymer-lipid hybrid nanoparticle system. J Pharmacol Exp Ther 317:1372–1381
146.
go back to reference Pacurari M, Castranova V, Vallyathan V (2010) Single- and multi-wall carbon nanotubes versus asbestos: are the carbon nanotubes a new health risk to humans? J Toxicol Environ Health A 73:378–395 Pacurari M, Castranova V, Vallyathan V (2010) Single- and multi-wall carbon nanotubes versus asbestos: are the carbon nanotubes a new health risk to humans? J Toxicol Environ Health A 73:378–395
147.
go back to reference Wang H, Wang J, Deng X et al (2004) Biodistribution of carbon single-wall carbon nanotubes in mice. J Nanosci Nanotechnol 4:1019–1024 Wang H, Wang J, Deng X et al (2004) Biodistribution of carbon single-wall carbon nanotubes in mice. J Nanosci Nanotechnol 4:1019–1024
148.
go back to reference Pantarotto D, Singh R, McCarthy D et al (2004) Functionalized carbon nanotubes for plasmid DNA gene delivery. Angew Chem Int Ed Engl 43:5242–5246 Pantarotto D, Singh R, McCarthy D et al (2004) Functionalized carbon nanotubes for plasmid DNA gene delivery. Angew Chem Int Ed Engl 43:5242–5246
149.
go back to reference Ji Z, Zhang D, Li L et al (2009) The hepatotoxicity of multi-walled carbon nanotubes in mice. Nanotechnol 20:445101 Ji Z, Zhang D, Li L et al (2009) The hepatotoxicity of multi-walled carbon nanotubes in mice. Nanotechnol 20:445101
150.
go back to reference Huczko A, Lange H (2001) Carbon nanotubes: experimental evidence for a null risk of skin irritation and allergy. Fullerene Sci Technol 9:247–250 Huczko A, Lange H (2001) Carbon nanotubes: experimental evidence for a null risk of skin irritation and allergy. Fullerene Sci Technol 9:247–250
151.
go back to reference Murray AR, Kisin E, Leonard SS et al (2009) Oxidative stress and inflammatory response in dermal toxicity of single-walled carbon nanotubes. Toxicol 257:161–171 Murray AR, Kisin E, Leonard SS et al (2009) Oxidative stress and inflammatory response in dermal toxicity of single-walled carbon nanotubes. Toxicol 257:161–171
152.
go back to reference Ma-Hock L, Treumann S, Strauss V et al (2009) Inhalation toxicity of multiwall carbon nanotubes in rats exposed for 3 months. Toxicol Sci 112:468–481 Ma-Hock L, Treumann S, Strauss V et al (2009) Inhalation toxicity of multiwall carbon nanotubes in rats exposed for 3 months. Toxicol Sci 112:468–481
153.
go back to reference Mitchell LA, Gao J, Wal RV et al (2007) Pulmonary and systemic immune response to inhaled multiwalled carbon nanotubes. Toxicol Sci 100:203–214 Mitchell LA, Gao J, Wal RV et al (2007) Pulmonary and systemic immune response to inhaled multiwalled carbon nanotubes. Toxicol Sci 100:203–214
154.
go back to reference Poland CA, Duffin R, Kinloch I et al (2008) Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study. Nat Nanotechnol 3:423–428 Poland CA, Duffin R, Kinloch I et al (2008) Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study. Nat Nanotechnol 3:423–428
155.
go back to reference Takagi A, Hirose A, Nishimura T et al (2008) Induction of mesothelioma in p53 ± mouse by intraperitoneal application of multi-wall carbon nanotube. J Toxicol Sci 33:105–116 Takagi A, Hirose A, Nishimura T et al (2008) Induction of mesothelioma in p53 ± mouse by intraperitoneal application of multi-wall carbon nanotube. J Toxicol Sci 33:105–116
156.
go back to reference Sakamoto Y, Nakae D, Fukumori N et al (2009) Induction of mesothelioma by a single intrascrotal administration of multi-wall carbon nanotube in intact male Fischer 344 rats. J Toxicol Sci 34:65–76 Sakamoto Y, Nakae D, Fukumori N et al (2009) Induction of mesothelioma by a single intrascrotal administration of multi-wall carbon nanotube in intact male Fischer 344 rats. J Toxicol Sci 34:65–76
157.
go back to reference Pacurari M, Yin XJ, Ding M et al (2008) Oxidative and molecular interactions of multi-wall carbon nanotubes (MWCNT) in normal and malignant human mesothelial cells. Nanotoxicol 2:155–170 Pacurari M, Yin XJ, Ding M et al (2008) Oxidative and molecular interactions of multi-wall carbon nanotubes (MWCNT) in normal and malignant human mesothelial cells. Nanotoxicol 2:155–170
158.
go back to reference Pacurari M, Yin XJ, Zhao J et al (2008) Raw single-wall carbon nanotubes induce oxidative stress and activate MAPKs, AP-1, NF-kappaB, and Akt in normal and malignant human mesothelial cells. Environ Health Perspect 116:1211–1217 Pacurari M, Yin XJ, Zhao J et al (2008) Raw single-wall carbon nanotubes induce oxidative stress and activate MAPKs, AP-1, NF-kappaB, and Akt in normal and malignant human mesothelial cells. Environ Health Perspect 116:1211–1217
159.
go back to reference Wang L, Mercer RR, Rojanasakul Y et al (2010) Direct fibrogenic effects of dispersed single-walled carbon nanotubes on human lung fibroblasts. J Toxicol Environ Health A 73:410–422 Wang L, Mercer RR, Rojanasakul Y et al (2010) Direct fibrogenic effects of dispersed single-walled carbon nanotubes on human lung fibroblasts. J Toxicol Environ Health A 73:410–422
160.
go back to reference Lindberg HK, Falck GC, Suhonen S et al (2009) Genotoxicity of nanomaterials: DNA damage and micronuclei induced by carbon nanotubes and graphite nanofibres in human bronchial epithelial cells in vitro. Toxicol Lett 186:166–173 Lindberg HK, Falck GC, Suhonen S et al (2009) Genotoxicity of nanomaterials: DNA damage and micronuclei induced by carbon nanotubes and graphite nanofibres in human bronchial epithelial cells in vitro. Toxicol Lett 186:166–173
161.
go back to reference Sayes CM, Liang F, Hudson JL et al (2006) Functionalization density dependence of single-walled carbon nanotubes cytotoxicity in vitro. Toxicol Lett 161:135–142 Sayes CM, Liang F, Hudson JL et al (2006) Functionalization density dependence of single-walled carbon nanotubes cytotoxicity in vitro. Toxicol Lett 161:135–142
162.
go back to reference Monteiro-Riviere NA, Nemanich RJ, Inman AO et al (2005) Multi-walled carbon nanotube interactions with human epidermal keratinocytes. Toxicol Lett 155:377–384 Monteiro-Riviere NA, Nemanich RJ, Inman AO et al (2005) Multi-walled carbon nanotube interactions with human epidermal keratinocytes. Toxicol Lett 155:377–384
163.
go back to reference Jia G, Wang H, Yan L, Wang X et al (2005) Cytotoxicity of carbon nanomaterials: single-wall nanotube, multi-wall nanotube, and fullerene. Environ Sci Technol 39:1378–1383 Jia G, Wang H, Yan L, Wang X et al (2005) Cytotoxicity of carbon nanomaterials: single-wall nanotube, multi-wall nanotube, and fullerene. Environ Sci Technol 39:1378–1383
164.
go back to reference Kagan VE, Tyurina YY, Tyurin VA et al (2006) Direct and indirect effects of single walled carbon nanotubes on RAW 264.7 macrophages: role of iron. Toxicol Lett 165:88–100 Kagan VE, Tyurina YY, Tyurin VA et al (2006) Direct and indirect effects of single walled carbon nanotubes on RAW 264.7 macrophages: role of iron. Toxicol Lett 165:88–100
165.
go back to reference Simon-Deckers A, Gouget B, Mayne-L’hermite M et al (2008) In vitro investigation of oxide nanoparticle and carbon nanotube toxicity and intracellular accumulation in A549 human pneumocytes. Toxicol 253:137–146 Simon-Deckers A, Gouget B, Mayne-L’hermite M et al (2008) In vitro investigation of oxide nanoparticle and carbon nanotube toxicity and intracellular accumulation in A549 human pneumocytes. Toxicol 253:137–146
166.
go back to reference Hardman R (2006) A toxicologic review of quantum dots: toxicity depends on physicochemical and environmental factors. Environ Health Perspect 114:165–172 Hardman R (2006) A toxicologic review of quantum dots: toxicity depends on physicochemical and environmental factors. Environ Health Perspect 114:165–172
167.
go back to reference Aldana J, Wang YA, Peng X (2001) Photochemical instability of CdSe nanocrystals coated by hydrophilic thiols. J Am Chem Soc 123:8844–8850 Aldana J, Wang YA, Peng X (2001) Photochemical instability of CdSe nanocrystals coated by hydrophilic thiols. J Am Chem Soc 123:8844–8850
168.
go back to reference Aldana J, Lavelle N, Wang Y et al (2005) Size-dependent dissociation pH of thiolate ligands from cadmium chalcogenide nanocrystals. J Am Chem Soc 127:2496–2504 Aldana J, Lavelle N, Wang Y et al (2005) Size-dependent dissociation pH of thiolate ligands from cadmium chalcogenide nanocrystals. J Am Chem Soc 127:2496–2504
169.
go back to reference Kim S, Bawendi MG (2003) Oligomeric ligands for luminescent and stable nanocrystal quantum dots. J Am Chem Soc 125:14652–14653 Kim S, Bawendi MG (2003) Oligomeric ligands for luminescent and stable nanocrystal quantum dots. J Am Chem Soc 125:14652–14653
170.
go back to reference Tsay JM, Michalet X (2005) New light on quantum dot cytotoxicity. Chem Biol 12:1159–1161 Tsay JM, Michalet X (2005) New light on quantum dot cytotoxicity. Chem Biol 12:1159–1161
171.
go back to reference Green M, Howman E (2005) Semiconductor quantum dots and free radical induced DNA nicking. Chem Commun (Camb)7:121–123 Green M, Howman E (2005) Semiconductor quantum dots and free radical induced DNA nicking. Chem Commun (Camb)7:121–123
172.
go back to reference Ipe BI, Lehnig M, Niemeyer CM (2005) On the generation of free radical species from quantum dots. Small 1:706–709 Ipe BI, Lehnig M, Niemeyer CM (2005) On the generation of free radical species from quantum dots. Small 1:706–709
173.
go back to reference Choi AO, Brown SE, Szyf M, Maysinger D (2008) Quantum dot-induced epigenetic and genotoxic changes in human breast cancer cells. J Mol Med 86:291–302 Choi AO, Brown SE, Szyf M, Maysinger D (2008) Quantum dot-induced epigenetic and genotoxic changes in human breast cancer cells. J Mol Med 86:291–302
174.
go back to reference Hoshino A, Fujioka K, Oku T et al (2004) Physicochemical properties and cellular ttoxicity of nanocrystal quantum dots depend on their surface modification. Nano Lett 4:2163–2169 Hoshino A, Fujioka K, Oku T et al (2004) Physicochemical properties and cellular ttoxicity of nanocrystal quantum dots depend on their surface modification. Nano Lett 4:2163–2169
175.
go back to reference Selvan ST, Tan TT, Ying JY (2005) Robust, non-cytotoxic, silica-coated CdSe quantum dots with efficient photoluminescence. Adv Mater 17:1620–1625 Selvan ST, Tan TT, Ying JY (2005) Robust, non-cytotoxic, silica-coated CdSe quantum dots with efficient photoluminescence. Adv Mater 17:1620–1625
176.
go back to reference Guo G, Liu W, Liang J et al (2007) Probing the cytotoxicity of CdSe quantum dots with surface modification. Material Lett 61:1641–1644 Guo G, Liu W, Liang J et al (2007) Probing the cytotoxicity of CdSe quantum dots with surface modification. Material Lett 61:1641–1644
177.
go back to reference Larese FF, D’Agostin F, Crosera M et al (2009) Human skin penetration of silver nanoparticles through intact and damaged skin. Toxicol 255:33–37 Larese FF, D’Agostin F, Crosera M et al (2009) Human skin penetration of silver nanoparticles through intact and damaged skin. Toxicol 255:33–37
178.
go back to reference Chen X, Schluesener HJ (2008) Nanosilver: a nanoproduct in medical application. Toxicol Lett 176:1–12 Chen X, Schluesener HJ (2008) Nanosilver: a nanoproduct in medical application. Toxicol Lett 176:1–12
179.
go back to reference Hussain SM, Hess KL, Gearhart JM et al (2005) In vitro toxicity of nanoparticles in BRL 3A rat liver cells. Toxicol In Vitro 19:975–983 Hussain SM, Hess KL, Gearhart JM et al (2005) In vitro toxicity of nanoparticles in BRL 3A rat liver cells. Toxicol In Vitro 19:975–983
180.
go back to reference Elechiguerra JL, Burt JL, Morones JR et al (2005) Interaction of silver nanoparticles with HIV-1. J Nanobiotechnol 3:6 Elechiguerra JL, Burt JL, Morones JR et al (2005) Interaction of silver nanoparticles with HIV-1. J Nanobiotechnol 3:6
181.
go back to reference Ji JH, Jung JH, Kim SS et al (2007) Twenty-eight-day inhalation toxicity study of silver nanoparticles in Sprague-Dawley rats. Inhal Toxicol 19:857–871 Ji JH, Jung JH, Kim SS et al (2007) Twenty-eight-day inhalation toxicity study of silver nanoparticles in Sprague-Dawley rats. Inhal Toxicol 19:857–871
182.
go back to reference Sung JH, Ji JH, Yoon JU et al (2008) Lung function changes in Sprague-Dawley rats after prolonged inhalation exposure to silver nanoparticles. Inhal Toxicol 20:567–574 Sung JH, Ji JH, Yoon JU et al (2008) Lung function changes in Sprague-Dawley rats after prolonged inhalation exposure to silver nanoparticles. Inhal Toxicol 20:567–574
183.
go back to reference Sung JH, Ji JH, Park JD et al (2009) Subchronic inhalation toxicity of silver nanoparticles. Toxicol Sci 108:452–461 Sung JH, Ji JH, Park JD et al (2009) Subchronic inhalation toxicity of silver nanoparticles. Toxicol Sci 108:452–461
184.
go back to reference Goodman CM, McCusker CD, Yilmaz T et al (2004) Toxicity of gold nanoparticles functionalized with cationic and anionic side chains. Bioconjug Chem 15:897–900 Goodman CM, McCusker CD, Yilmaz T et al (2004) Toxicity of gold nanoparticles functionalized with cationic and anionic side chains. Bioconjug Chem 15:897–900
185.
go back to reference Connor EE, Mwamuka J, Gole A et al (2005) Gold nanoparticles are taken up by human cells but do not cause acute cytotoxicity. Small 1:325–327 Connor EE, Mwamuka J, Gole A et al (2005) Gold nanoparticles are taken up by human cells but do not cause acute cytotoxicity. Small 1:325–327
186.
go back to reference Hauck TS, Ghazani AA, Chan WC (2008) Assessing the effect of surface chemistry on gold nanorod uptake, toxicity, and gene expression in mammalian cells. Small 4:153–159 Hauck TS, Ghazani AA, Chan WC (2008) Assessing the effect of surface chemistry on gold nanorod uptake, toxicity, and gene expression in mammalian cells. Small 4:153–159
187.
go back to reference Shukla R, Bansal V, Chaudhary M et al (2005) Biocompatibility of gold nanoparticles and their endocytotic fate inside the cellular compartment: a microscopic overview. Langmuir 21:10644–10654 Shukla R, Bansal V, Chaudhary M et al (2005) Biocompatibility of gold nanoparticles and their endocytotic fate inside the cellular compartment: a microscopic overview. Langmuir 21:10644–10654
188.
go back to reference Pan Y, Neuss S, Leifert A et al (2007) Size-dependent cytotoxicity of gold nanoparticles. Small 3:1941–1949 Pan Y, Neuss S, Leifert A et al (2007) Size-dependent cytotoxicity of gold nanoparticles. Small 3:1941–1949
189.
go back to reference Patra HK, Banerjee S, Chaudhuri U, Lahiri P et al (2007) Cell selective response to gold nanoparticles. Nanomedicine 3:111–119 Patra HK, Banerjee S, Chaudhuri U, Lahiri P et al (2007) Cell selective response to gold nanoparticles. Nanomedicine 3:111–119
190.
go back to reference Zharov VP, Mercer KE, Galitovskaya EN et al (2006) Photothermal nanotherapeutics and nanodiagnostics for selective killing of bacteria targeted with gold nanoparticles. Biophys J 90:619–627 Zharov VP, Mercer KE, Galitovskaya EN et al (2006) Photothermal nanotherapeutics and nanodiagnostics for selective killing of bacteria targeted with gold nanoparticles. Biophys J 90:619–627
191.
go back to reference Lewinski N, Colvin V, Drezek R (2008) Cytotoxicity of nanoparticles. Small 4:26–49 Lewinski N, Colvin V, Drezek R (2008) Cytotoxicity of nanoparticles. Small 4:26–49
192.
go back to reference Takenaka S, Karg E, Kreyling WG et al (2006) Distribution pattern of inhaled ultrafine gold particles in the rat lung. Inhal Toxicol 18:733–740 Takenaka S, Karg E, Kreyling WG et al (2006) Distribution pattern of inhaled ultrafine gold particles in the rat lung. Inhal Toxicol 18:733–740
193.
go back to reference Hillyer JF, Albrecht RM (2001) Gastrointestinal persorption and tissue distribution of differently sized colloidal gold nanoparticles. J Pharm Sci 90:1927–1936 Hillyer JF, Albrecht RM (2001) Gastrointestinal persorption and tissue distribution of differently sized colloidal gold nanoparticles. J Pharm Sci 90:1927–1936
194.
go back to reference Paciotti GF, Myer L, Weinreich D, Goia D et al (2004) Colloidal gold: a novel nanoparticle vector for tumor directed drug delivery. Drug Deliv 11:169–183 Paciotti GF, Myer L, Weinreich D, Goia D et al (2004) Colloidal gold: a novel nanoparticle vector for tumor directed drug delivery. Drug Deliv 11:169–183
195.
go back to reference Hainfeld JF, Slatkin DN, Smilowitz HM (2004) The use of gold nanoparticles to enhance radiotherapy in mice. Phys Med Biol 49:N309–N315 Hainfeld JF, Slatkin DN, Smilowitz HM (2004) The use of gold nanoparticles to enhance radiotherapy in mice. Phys Med Biol 49:N309–N315
196.
go back to reference Cho WS, Cho M, Jeong J et al (2009) Acute toxicity and pharmacokinetics of 13 nm-sized PEG-coated gold nanoparticles. Toxicol Appl Pharmacol 236:16–24 Cho WS, Cho M, Jeong J et al (2009) Acute toxicity and pharmacokinetics of 13 nm-sized PEG-coated gold nanoparticles. Toxicol Appl Pharmacol 236:16–24
197.
go back to reference Chithrani BD, Ghazani AA, Chan WC (2006) Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells. Nano Lett 6:662–668 Chithrani BD, Ghazani AA, Chan WC (2006) Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells. Nano Lett 6:662–668
198.
go back to reference Pernodet N, Fang X, Sun Y, Bakhtina A et al (2006) Adverse effects of citrate/gold nanoparticles on human dermal fibroblasts. Small 2:766–773 Pernodet N, Fang X, Sun Y, Bakhtina A et al (2006) Adverse effects of citrate/gold nanoparticles on human dermal fibroblasts. Small 2:766–773
199.
go back to reference Gu YJ, Cheng J, Lin CC et al (2009) Nuclear penetration of surface functionalized gold nanoparticles. Toxicol Appl Pharmacol 237:196–204 Gu YJ, Cheng J, Lin CC et al (2009) Nuclear penetration of surface functionalized gold nanoparticles. Toxicol Appl Pharmacol 237:196–204
200.
go back to reference Ma-Hock L, Burkhardt S, Strauss V et al (2009) Development of a short-term inhalation test in the rat using nano-titanium dioxide as a model substance. Inhal Toxicol 21:102–118 Ma-Hock L, Burkhardt S, Strauss V et al (2009) Development of a short-term inhalation test in the rat using nano-titanium dioxide as a model substance. Inhal Toxicol 21:102–118
201.
go back to reference Wang J, Chen C, Liu Y et al (2008) Potential neurological lesion after nasal instillation of TiO2 nanoparticles in the anatase and rutile crystal phases. Toxicol Lett 183:72–80 Wang J, Chen C, Liu Y et al (2008) Potential neurological lesion after nasal instillation of TiO2 nanoparticles in the anatase and rutile crystal phases. Toxicol Lett 183:72–80
202.
go back to reference Wang J, Liu Y, Jiao F et al (2008) Time-dependent translocation and potential impairment on central nervous system by intranasally instilled TiO2 nanoparticles. Toxicology 254:82–90 Wang J, Liu Y, Jiao F et al (2008) Time-dependent translocation and potential impairment on central nervous system by intranasally instilled TiO2 nanoparticles. Toxicology 254:82–90
203.
go back to reference van Ravenzwaay B, Landsiedel R, Fabian E et al (2009) Comparing fate and effects of three particles of different surface properties: nano-TiO(2), pigmentary TiO2 and quartz. Toxicol Lett 186:152–159 van Ravenzwaay B, Landsiedel R, Fabian E et al (2009) Comparing fate and effects of three particles of different surface properties: nano-TiO(2), pigmentary TiO2 and quartz. Toxicol Lett 186:152–159
204.
go back to reference Zhang Z, Kleinstreuer C, Donohue JF et al (2005) Comparison of micro- and nano-size particle depositions in a human upper airway model. J Aerosol Sci 36:211–233 Zhang Z, Kleinstreuer C, Donohue JF et al (2005) Comparison of micro- and nano-size particle depositions in a human upper airway model. J Aerosol Sci 36:211–233
205.
go back to reference Donaldson K, Stone V, Clouter A et al (2001) Ultrafine particles. Occup Environ Med 58:211–216 Donaldson K, Stone V, Clouter A et al (2001) Ultrafine particles. Occup Environ Med 58:211–216
206.
go back to reference Ferin J, Oberdorster G, Penney DP (1992) Pulmonary retention of ultrafine and fine particles in rats. Am J Respir Cell Mol Biol 6:535–542 Ferin J, Oberdorster G, Penney DP (1992) Pulmonary retention of ultrafine and fine particles in rats. Am J Respir Cell Mol Biol 6:535–542
207.
go back to reference Oberdorster G, Ferin J, Lehnert BE (1994) Correlation between particle size, in vivo particle persistence, and lung injury. Environ Health Perspect 102(Suppl 5):173–179 Oberdorster G, Ferin J, Lehnert BE (1994) Correlation between particle size, in vivo particle persistence, and lung injury. Environ Health Perspect 102(Suppl 5):173–179
208.
go back to reference Renwick LC, Brown D, Clouter A, Donaldson K (2004) Increased inflammation and altered macrophage chemotactic responses caused by two ultrafine particle types. Occup Environ Med 61:442–447 Renwick LC, Brown D, Clouter A, Donaldson K (2004) Increased inflammation and altered macrophage chemotactic responses caused by two ultrafine particle types. Occup Environ Med 61:442–447
209.
go back to reference Grassian VH, O’Shaughnessy PT, Adamcakova-Dodd A et al (2007) Inhalation exposure study of titanium dioxide nanoparticles with a primary particle size of 2 to 5 nm. Environ Health Perspect 115:397–402 Grassian VH, O’Shaughnessy PT, Adamcakova-Dodd A et al (2007) Inhalation exposure study of titanium dioxide nanoparticles with a primary particle size of 2 to 5 nm. Environ Health Perspect 115:397–402
210.
go back to reference Chen HW, Su SF, Chien CT et al (2006) Titanium dioxide nanoparticles induce emphysema-like lung injury in mice. Faseb J 20:2393–2395 Chen HW, Su SF, Chien CT et al (2006) Titanium dioxide nanoparticles induce emphysema-like lung injury in mice. Faseb J 20:2393–2395
211.
go back to reference Bermudez E, Mangum JB, Wong BA et al (2004) Pulmonary responses of mice, rats, and hamsters to subchronic inhalation of ultrafine titanium dioxide particles. Toxicol Sci 77:347–357 Bermudez E, Mangum JB, Wong BA et al (2004) Pulmonary responses of mice, rats, and hamsters to subchronic inhalation of ultrafine titanium dioxide particles. Toxicol Sci 77:347–357
212.
go back to reference Shimizu M, Tainaka H, Oba T et al (2009) Maternal exposure to nanoparticulate titanium dioxide during the prenatal period alters gene expression related to brain development in the mouse. Part Fibre Toxicol 6:20 Shimizu M, Tainaka H, Oba T et al (2009) Maternal exposure to nanoparticulate titanium dioxide during the prenatal period alters gene expression related to brain development in the mouse. Part Fibre Toxicol 6:20
213.
go back to reference Gurr JR, Wang AS, Chen CH et al (2005) Ultrafine titanium dioxide particles in the absence of photoactivation can induce oxidative damage to human bronchial epithelial cells. Toxicology 213:66–73 Gurr JR, Wang AS, Chen CH et al (2005) Ultrafine titanium dioxide particles in the absence of photoactivation can induce oxidative damage to human bronchial epithelial cells. Toxicology 213:66–73
214.
go back to reference Churg A, Gilks B, Dai J (1999) Induction of fibrogenic mediators by fine and ultrafine titanium dioxide in rat tracheal explants. Am J Physiol 277:L975–L982 Churg A, Gilks B, Dai J (1999) Induction of fibrogenic mediators by fine and ultrafine titanium dioxide in rat tracheal explants. Am J Physiol 277:L975–L982
215.
go back to reference Kim JK, Lee WK, Lee EJ et al (1999) Mechanism of silica- and titanium dioxide-induced cytotoxicity in alveolar macrophages. J Toxicol Environ Health A 58:437–450 Kim JK, Lee WK, Lee EJ et al (1999) Mechanism of silica- and titanium dioxide-induced cytotoxicity in alveolar macrophages. J Toxicol Environ Health A 58:437–450
216.
go back to reference Falck GC, Lindberg HK, Suhonen S et al (2009) Genotoxic effects of nanosized and fine TiO2. Hum Exp Toxicol 28:339–352 Falck GC, Lindberg HK, Suhonen S et al (2009) Genotoxic effects of nanosized and fine TiO2. Hum Exp Toxicol 28:339–352
217.
go back to reference Schulz J, Hohenberg H, Pflucker F et al (2002) Distribution of sunscreens on skin. Adv Drug Deliv Rev 54(Suppl 1):S157–S163 Schulz J, Hohenberg H, Pflucker F et al (2002) Distribution of sunscreens on skin. Adv Drug Deliv Rev 54(Suppl 1):S157–S163
218.
go back to reference Kiss B, Biro T, Czifra G, Toth BI et al (2008) Investigation of micronized titanium dioxide penetration in human skin xenografts and its effect on cellular functions of human skin-derived cells. Exp Dermatol 17:659–667 Kiss B, Biro T, Czifra G, Toth BI et al (2008) Investigation of micronized titanium dioxide penetration in human skin xenografts and its effect on cellular functions of human skin-derived cells. Exp Dermatol 17:659–667
219.
go back to reference Jin CY, Zhu BS, Wang XF et al (2008) Cytotoxicity of titanium dioxide nanoparticles in mouse fibroblast cells. Chem Res Toxicol 21:1871–1877 Jin CY, Zhu BS, Wang XF et al (2008) Cytotoxicity of titanium dioxide nanoparticles in mouse fibroblast cells. Chem Res Toxicol 21:1871–1877
220.
go back to reference Griffitt RJ, Luo J, Gao J et al (2008) Effects of particle composition and species on toxicity of metallic nanomaterials in aquatic organisms. Environ Toxicol Chem 27:1972–1978 Griffitt RJ, Luo J, Gao J et al (2008) Effects of particle composition and species on toxicity of metallic nanomaterials in aquatic organisms. Environ Toxicol Chem 27:1972–1978
221.
go back to reference Zhang X, Sun H, Zhang ZN et al (2007) Enhanced bioaccumulation of cadmium in carp in the presence of titanium dioxide nanoparticles. Chemosphere 67:160–166 Zhang X, Sun H, Zhang ZN et al (2007) Enhanced bioaccumulation of cadmium in carp in the presence of titanium dioxide nanoparticles. Chemosphere 67:160–166
222.
go back to reference Hao L, Wang Z, Xing B (2009) Effect of sub-acute exposure to TiO2 nanoparticles on oxidative stress and histopathological changes in Juvenile Carp (Cyprinus carpio). J Environ Sci (China) 21:1459–1466 Hao L, Wang Z, Xing B (2009) Effect of sub-acute exposure to TiO2 nanoparticles on oxidative stress and histopathological changes in Juvenile Carp (Cyprinus carpio). J Environ Sci (China) 21:1459–1466
223.
go back to reference Aruoja V, Dubourguier HC, Kasemets K et al (2009) Toxicity of nanoparticles of CuO, ZnO and TiO2 to microalgae Pseudokirchneriella subcapitata. Sci Total Environ 407:1461–1468 Aruoja V, Dubourguier HC, Kasemets K et al (2009) Toxicity of nanoparticles of CuO, ZnO and TiO2 to microalgae Pseudokirchneriella subcapitata. Sci Total Environ 407:1461–1468
224.
go back to reference Hartmann NB, Von der Kammer F, Hofmann T et al (2009) Algal testing of titanium dioxide nanoparticles-testing considerations, inhibitory effects and modification of cadmium bioavailability. Toxicol 269:190–197 Hartmann NB, Von der Kammer F, Hofmann T et al (2009) Algal testing of titanium dioxide nanoparticles-testing considerations, inhibitory effects and modification of cadmium bioavailability. Toxicol 269:190–197
225.
go back to reference Gojova A, Guo B, Kota RS et al (2007) Induction of inflammation in vascular endothelial cells by metal oxide nanoparticles: effect of particle composition. Environ Health Perspect 115:403–409 Gojova A, Guo B, Kota RS et al (2007) Induction of inflammation in vascular endothelial cells by metal oxide nanoparticles: effect of particle composition. Environ Health Perspect 115:403–409
226.
go back to reference Jeng HA, Swanson J (2006) Toxicity of metal oxide nanoparticles in mammalian cells. J Environ Sci Health A Tox Hazard Subst Environ Eng 41:2699–2711 Jeng HA, Swanson J (2006) Toxicity of metal oxide nanoparticles in mammalian cells. J Environ Sci Health A Tox Hazard Subst Environ Eng 41:2699–2711
227.
go back to reference Brunner TJ, Wick P, Manser P et al (2006) In vitro cytotoxicity of oxide nanoparticles: comparison to asbestos, silica, and the effect of particle solubility. Environ Sci Technol 40:4374–4381 Brunner TJ, Wick P, Manser P et al (2006) In vitro cytotoxicity of oxide nanoparticles: comparison to asbestos, silica, and the effect of particle solubility. Environ Sci Technol 40:4374–4381
228.
go back to reference Reddy KM, Feris K, Bell J et al (2007) Selective toxicity of zinc oxide nanoparticles to prokaryotic and eukaryotic systems. Appl Phys Lett 90:2139021–2139023 Reddy KM, Feris K, Bell J et al (2007) Selective toxicity of zinc oxide nanoparticles to prokaryotic and eukaryotic systems. Appl Phys Lett 90:2139021–2139023
229.
go back to reference Lanone S, Rogerieux F, Geys J et al (2009) Comparative toxicity of 24 manufactured nanoparticles in human alveolar epithelial and macrophage cell lines. Part Fibre Toxicol 6:14 Lanone S, Rogerieux F, Geys J et al (2009) Comparative toxicity of 24 manufactured nanoparticles in human alveolar epithelial and macrophage cell lines. Part Fibre Toxicol 6:14
230.
go back to reference Sayes CM, Reed KL, Warheit DB (2007) Assessing toxicity of fine and nanoparticles: comparing in vitro measurements to in vivo pulmonary toxicity profiles. Toxicol Sci 97:163–180 Sayes CM, Reed KL, Warheit DB (2007) Assessing toxicity of fine and nanoparticles: comparing in vitro measurements to in vivo pulmonary toxicity profiles. Toxicol Sci 97:163–180
231.
go back to reference Adams LK, Lyon DY, Alvarez PJ (2006) Comparative eco-toxicity of nanoscale TiO2, SiO2, and ZnO water suspensions. Water Res 40:3527–3532 Adams LK, Lyon DY, Alvarez PJ (2006) Comparative eco-toxicity of nanoscale TiO2, SiO2, and ZnO water suspensions. Water Res 40:3527–3532
232.
go back to reference Huang Z, Zheng X, Yan D et al (2008) Toxicological effect of ZnO nanoparticles based on bacteria. Langmuir 24:4140–4144 Huang Z, Zheng X, Yan D et al (2008) Toxicological effect of ZnO nanoparticles based on bacteria. Langmuir 24:4140–4144
233.
go back to reference Wu B, Wang Y, Lee YH, Horst A et al (2010) Comparative eco-toxicities of nano-ZnO particles under aquatic and aerosol exposure modes. Environ Sci Technol 44:1484–1489 Wu B, Wang Y, Lee YH, Horst A et al (2010) Comparative eco-toxicities of nano-ZnO particles under aquatic and aerosol exposure modes. Environ Sci Technol 44:1484–1489
234.
go back to reference Franklin NM, Rogers NJ, Apte SC et al (2007) Comparative toxicity of nanoparticulate ZnO, bulk ZnO, and ZnCl2 to a freshwater microalga (Pseudokirchneriella subcapitata): the importance of particle solubility. Environ Sci Technol 41:8484–8490 Franklin NM, Rogers NJ, Apte SC et al (2007) Comparative toxicity of nanoparticulate ZnO, bulk ZnO, and ZnCl2 to a freshwater microalga (Pseudokirchneriella subcapitata): the importance of particle solubility. Environ Sci Technol 41:8484–8490
235.
go back to reference Zhu X, Zhu L, Duan Z et al (2008) Comparative toxicity of several metal oxide nanoparticle aqueous suspensions to Zebrafish (Danio rerio) early developmental stage. J Environ Sci Health A Tox Hazard Subst Environ Eng 43:278–284 Zhu X, Zhu L, Duan Z et al (2008) Comparative toxicity of several metal oxide nanoparticle aqueous suspensions to Zebrafish (Danio rerio) early developmental stage. J Environ Sci Health A Tox Hazard Subst Environ Eng 43:278–284
236.
go back to reference Lee CW, Mahendra S, Zodrow K (2010) Developmental phytotoxicity of metal oxide nanoparticles to Arabidopsis thaliana. Environ Toxicol Chem 29:669–675 Lee CW, Mahendra S, Zodrow K (2010) Developmental phytotoxicity of metal oxide nanoparticles to Arabidopsis thaliana. Environ Toxicol Chem 29:669–675
237.
go back to reference Lin D, Xing B (2007) Phytotoxicity of nanoparticles: inhibition of seed germination and root growth. Environ Pollut 150:243–250 Lin D, Xing B (2007) Phytotoxicity of nanoparticles: inhibition of seed germination and root growth. Environ Pollut 150:243–250
238.
go back to reference Blinova I, Ivask A, Heinlaan M et al (2010) Ecotoxicity of nanoparticles of CuO and ZnO in natural water. Environ Pollut 158:41–47 Blinova I, Ivask A, Heinlaan M et al (2010) Ecotoxicity of nanoparticles of CuO and ZnO in natural water. Environ Pollut 158:41–47
239.
go back to reference Navarro E, Piccapietra F, Wagner B et al (2008) Toxicity of silver nanoparticles to Chlamydomonas reinhardtii. Environ Sci Technol 42:8959–8964 Navarro E, Piccapietra F, Wagner B et al (2008) Toxicity of silver nanoparticles to Chlamydomonas reinhardtii. Environ Sci Technol 42:8959–8964
240.
go back to reference Farre M, Gajda-Schrantz K, Kantiani L et al (2009) Ecotoxicity and analysis of nanomaterials in the aquatic environment. Anal Bioanal Chem 393:81–95 Farre M, Gajda-Schrantz K, Kantiani L et al (2009) Ecotoxicity and analysis of nanomaterials in the aquatic environment. Anal Bioanal Chem 393:81–95
241.
go back to reference Bai W, Zhang Z, Tian W et al (2009) Toxicity of zinc oxide nanoparticles to zebrafish embryo: a physicochemical study of toxicity mechanism. J Nanopart Res. doi:10.1007/s11051-009-9740-9 Bai W, Zhang Z, Tian W et al (2009) Toxicity of zinc oxide nanoparticles to zebrafish embryo: a physicochemical study of toxicity mechanism. J Nanopart Res. doi:10.​1007/​s11051-009-9740-9
242.
go back to reference Wang H, Wick RL, Xing B (2009) Toxicity of nanoparticulate and bulk ZnO, Al2O3 and TiO2 to the nematode Caenorhabditis elegans. Environ Pollut 157:1171–1177 Wang H, Wick RL, Xing B (2009) Toxicity of nanoparticulate and bulk ZnO, Al2O3 and TiO2 to the nematode Caenorhabditis elegans. Environ Pollut 157:1171–1177
243.
go back to reference Deng X, Luan Q, Chen W et al (2009) Nanosized zinc oxide particles induce neural stem cell apoptosis. Nanotechnol 20:115101 Deng X, Luan Q, Chen W et al (2009) Nanosized zinc oxide particles induce neural stem cell apoptosis. Nanotechnol 20:115101
244.
go back to reference Takeda A, Ohnuma M, Sawashita J et al (1997) Zinc transport in the rat olfactory system. Neurosci Lett 225:69–71 Takeda A, Ohnuma M, Sawashita J et al (1997) Zinc transport in the rat olfactory system. Neurosci Lett 225:69–71
245.
go back to reference Persson E, Henriksson J, Tallkvist J et al (2003) Transport and subcellular distribution of intranasally administered zinc in the olfactory system of rats and pikes. Toxicol 191:97–108 Persson E, Henriksson J, Tallkvist J et al (2003) Transport and subcellular distribution of intranasally administered zinc in the olfactory system of rats and pikes. Toxicol 191:97–108
246.
go back to reference Xia T, Kovochich M, Liong M et al (2008) Comparison of the mechanism of toxicity of zinc oxide and cerium oxide nanoparticles based on dissolution and oxidative stress properties. ACS Nano 2:2121–2134 Xia T, Kovochich M, Liong M et al (2008) Comparison of the mechanism of toxicity of zinc oxide and cerium oxide nanoparticles based on dissolution and oxidative stress properties. ACS Nano 2:2121–2134
247.
go back to reference Tracy MA, Ward KL, Firouzabadian L et al (1999) Factors affecting the degradation rate of poly(lactide-co-glycolide) microspheres in vivo and in vitro. Biomaterials 20:1057–1062 Tracy MA, Ward KL, Firouzabadian L et al (1999) Factors affecting the degradation rate of poly(lactide-co-glycolide) microspheres in vivo and in vitro. Biomaterials 20:1057–1062
248.
go back to reference Nafee N, Schneider M, Schaefer UF et al (2009) Relevance of the colloidal stability of chitosan/PLGA nanoparticles on their cytotoxicity profile. Int J Pharm 381:130–139 Nafee N, Schneider M, Schaefer UF et al (2009) Relevance of the colloidal stability of chitosan/PLGA nanoparticles on their cytotoxicity profile. Int J Pharm 381:130–139
249.
go back to reference Mishra V, Gupta U, Jain NK (2009) Surface-engineered dendrimers: a solution for toxicity issues. J Biomater Sci Polym Ed 20:141–166 Mishra V, Gupta U, Jain NK (2009) Surface-engineered dendrimers: a solution for toxicity issues. J Biomater Sci Polym Ed 20:141–166
250.
go back to reference Malik N, Wiwattanapatapee R, Klopsch R et al (2000) Dendrimers: relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125I-labelled polyamidoamine dendrimers in vivo. J Control Release 65:133–148 Malik N, Wiwattanapatapee R, Klopsch R et al (2000) Dendrimers: relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125I-labelled polyamidoamine dendrimers in vivo. J Control Release 65:133–148
251.
go back to reference Heiden TC, Dengler E, Kao WJ et al (2007) Developmental toxicity of low generation PAMAM dendrimers in zebrafish. Toxicol Appl Pharmacol 225:70–79 Heiden TC, Dengler E, Kao WJ et al (2007) Developmental toxicity of low generation PAMAM dendrimers in zebrafish. Toxicol Appl Pharmacol 225:70–79
252.
go back to reference Jevprasesphant R, Penny J, Jalal R et al (2003) The influence of surface modification on the cytotoxicity of PAMAM dendrimers. Int J Pharm 252:263–266 Jevprasesphant R, Penny J, Jalal R et al (2003) The influence of surface modification on the cytotoxicity of PAMAM dendrimers. Int J Pharm 252:263–266
253.
go back to reference Chen HT, Neerman MF, Parrish AR et al (2004) Cytotoxicity, hemolysis, and acute in vivo toxicity of dendrimers based on melamine, candidate vehicles for drug delivery. J Am Chem Soc 126:10044–10048 Chen HT, Neerman MF, Parrish AR et al (2004) Cytotoxicity, hemolysis, and acute in vivo toxicity of dendrimers based on melamine, candidate vehicles for drug delivery. J Am Chem Soc 126:10044–10048
Metadata
Title
Relevance of Nanotechnology to Africa: Synthesis, Applications, and Safety
Authors
Ndeke Musee
Lucky Sikhwivhilu
Mary Gulumian
Copyright Year
2013
Publisher
Springer Berlin Heidelberg
DOI
https://doi.org/10.1007/978-3-642-29642-0_8