This chapter explores the integration of affective storytelling in virtual museum (VM) experience. The use of Information and Communication Technologies (ICT) affects the way people create, communicate and learn, opens novel opportunities and provides new means for museums to create narratives, express their points and provide quality experiences. Museums’ integration of new media, empowers people to construct their own understandings within an open-ended framework. ICT permeate cultural life, not only by introducing new forms of creative expression and meanings for art, but also by enriching, transforming and enhancing the museum experience. ICT in museums can empower curators to disseminate their ideas and facilitate understandings of the complexities regarding museum exhibits and thus develop aesthetic perception, sensitivities and creativity. In this chapter, the function and cultural significance of storytelling as such is addressed, before venturing into discussing digital storytelling vis-à-vis cultural heritage organizations’ practices. Furthermore, the potential of digital storytelling as fulcrum for rethinking museums as affective spaces in-dialogue with their audiences is delineated.