11. Summary and Conclusions

This chapter delves into the contentious hypothesis of chemical evolution, presenting a counterbalance to the often overoptimistic interpretations found in existing literature. It scrutinizes the selection of biomolecules, questioning why specific molecules were favored in the course of chemical evolution. The chapter challenges the notion that thermodynamic stability alone can explain the prevalence of certain biomolecules, such as proteinogenic amino acids and canonical nucleobases. It explores the enigmatic selection of D-ribose as the repeat unit in RNA, despite the existence of more stable alternatives. The text also raises thought-provoking questions about the role of aptamers and the concept of 'frozen accidents' in the origin of life. By addressing these overlooked issues, the chapter offers a fresh perspective on the chemical evolution hypothesis, inviting readers to question established narratives and engage with the complexities of this fascinating field.