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01-01-2014 | Original Paper

Synthesis and characterization of citric acid-based pH-sensitive biopolymeric hydrogels

Authors: D. S. Franklin, S. Guhanathan

Published in: Polymer Bulletin | Issue 1/2014

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Abstract

Biocompatible hydrogels based on citric acid (CA) with varying glycol unit, viz., ethylene glycol (EG), diethylene glycol and triethylene glycol were prepared along with acrylic acid. The formations of various hydrogels were confirmed using spectral techniques such as FT-IR and ¹H NMR. Thermal stability (thermogravimetric analysis, DTA and differential scanning calorimetry) and morphology (SEM) of the synthesized hydrogels were investigated. Swelling studies of hydrogels at various pH values ranging from 4.0 to 10.0 were also investigated. The results of swelling studies show that the percentage of swelling is comparatively higher at higher pH than lower pH. Swelling equilibrium for various hydrogels was also found. Increased composition of CA in hydrogels at different pH values of 4.0, 6.0, 7.4, 8.0 and 10.0 enhanced the swelling equilibrium.

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Title: Synthesis and characterization of citric acid-based pH-sensitive biopolymeric hydrogels
Authors: D. S. Franklin
S. Guhanathan
Publication date: 01-01-2014
Publisher: Springer Berlin Heidelberg
Published in: Polymer Bulletin / Issue 1/2014
Print ISSN: 0170-0839
Electronic ISSN: 1436-2449
DOI: https://doi.org/10.1007/s00289-013-1047-4

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