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Machine Learning Techniques for Structural Health Monitoring Read chapter Read first chapter

2020 | OriginalPaper | Chapter

The Preparation of Smart Magnetic Nanoparticles for Intracellular Hyperthermia

Authors : XiaoGang Yu, RenPeng Yang, ChengWei Wu, Wei Zhang, DongFeng Deng, XuXin Zhang, YanZhao Li

Published in: Proceedings of the 13th International Conference on Damage Assessment of Structures

Publisher: Springer Singapore

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Abstract

Magnetic induction hyperthermia is a new “green” cancer therapy method, which can destroy the tumor cells and undamage healthy cells. However, the difficulty of in vivo temperature rise control limits its clinical application. In this paper, we prepare a kind of smart magnetic nanoparticles for magnetic induction hyperthermia. The smart nanoparticles can self-control the temperature at 59.9 °C in the hyperthermia due to the low Curie temperature of nanoparticles. The formation mechanism of the smart magnetic nanoparticles is investigated. On the other hand, owing to the low thermal conductivity of the cell membrane, it is reasonable to believe that the intracellular hyperthermia is superior to extracellular hyperthermia. As such, we also discuss the feasibility of intracellular hyperthermia using the obtained smart magnetic nanoparticles. The results indicate that the temperature changes of the cell can meet the requirement of hyperthermia temperature when a single cell internalizes 2 pg of the smart magnetic nanoparticles.

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previous chapter Studies of Fibre Reinforced Polymer Samples with Embedded FBG Sensors
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Metadata
Title
The Preparation of Smart Magnetic Nanoparticles for Intracellular Hyperthermia
Authors
XiaoGang Yu
RenPeng Yang
ChengWei Wu
Wei Zhang
DongFeng Deng
XuXin Zhang
YanZhao Li
Copyright Year
2020
Publisher
Springer Singapore
Book
Proceedings of the 13th International Conference on Damage Assessment of Structures

Print ISBN: 978-981-13-8330-4

Electronic ISBN: 978-981-13-8331-1

Copyright Year: 2020

DOI
https://doi.org/10.1007/978-981-13-8331-1_75

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