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2017 | Book

Diagnostic and Therapeutic Nanomaterials Read chapter Read first chapter

Therapeutic and Diagnostic Nanomaterials

Author:  Devasena T

Publisher: Springer Singapore

Book Series : SpringerBriefs in Applied Sciences and Technology

Part of: Springer Professional "Wirtschaft+Technik" , Springer Professional "Technik"

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About this book

This brief highlights nanoparticles used in the diagnosis and treatment of prominent diseases and toxic conditions. Ecofriendly methods which are ideal for the synthesis of medicinally valued nanoparticles are explained and the characteristic features of these particles projected. The role of these particles in the therapeutic field, and the induced biological changes in some diseases are discussed. The main focus is on inflammation, oxidative stress and cellular membrane integrity alterations. The effect of nanoparticles on these changes produced by various agents are highlighted using in vitro and in vivo models. The mechanism of nanoparticles in ameliorating the biological changes is supported by relevant images and data. Finally, the brief demonstrates recent developments on the use of nanoparticles in diagnosis or sensing of some biological materials and biologically hazardous environmental materials.

Table of Contents

Frontmatter
Chapter 1. Diagnostic and Therapeutic Nanomaterials
Abstract
Identification or detection of a disease through its signs/symptoms or by analyzing the biomarkers is called diagnosis. Treatment of a disease after diagnosis is called therapy. Agents used for diagnosis and therapy are called diagnostics and therapeutics, respectively. Additionally, some instrumental methods or techniques are also used accordingly. Nanoparticles have wider applications in diagnosis and therapy due to their many unique properties, which are explained elsewhere. Nanomaterials of different morphologies and different forms, such as nanoconjugates and nanocomposites, are widely used for diagnosis and therapeutic purposes. Several reports indicate the high efficacy of nanodiagnostics and nanotherapeutics.
Devasena T
Chapter 2. Multifunctional Nanoparticles
Abstract
The functionalization of nanoparticles with one or more specific chemical moieties, so-called ligands, results in multifunctional nanoparticles. They are widely used in biomedical applications, especially drug delivery, cancer therapy, diagnostics, tissue engineering, and molecular biology.
Devasena T
Chapter 3. Biomarkers
Abstract
Biomarkers are accurately quantifiable indicators that are capable of reflecting normal biological processes, pathogenic processes, incidence or outcome of a disease, pharmacologic responses to a therapeutic intervention, or the adverse effects of a desired new drug.
Devasena T
Chapter 4. Diagnostic and Therapeutic Techniques
Abstract
The use of molecular probes for the visualization and investigation of the structure, function, characteristics, and processes of cells in a living organism is called molecular imaging. The probes bind to the target cells or molecules and indicate their presence by giving a quantifiable signal.
Devasena T
Chapter 5. Nanotoxicity and Risk Assessment
Abstract
The fields of research, medicine, materials science, metals, food, and electrical and electronics could not resist the production and use of nanoparticles because of their unique mechanical, physical, and chemical properties. Thus, nanotechnology plays a leading role in cutting-edge research and technology. Because nanoparticles are unique, their interactions with biological components such as cells and their vital molecules are also unique when compared to their bulk counterparts.
Devasena T
Chapter 6. Applications of Select Nanomaterials
Abstract
The diagnostic and therapeutic applications of nanomaterials are numerous. This chapter presents select examples of the biomedical applications of the following nanomaterials.
Devasena T
Metadata
Title
Therapeutic and Diagnostic Nanomaterials
Author
Devasena T
Copyright Year
2017
Publisher
Springer Singapore
Electronic ISBN
978-981-10-0923-5
Print ISBN
978-981-10-0921-1
DOI
https://doi.org/10.1007/978-981-10-0923-5