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Published in:
2009 | OriginalPaper | Chapter
Time Dependent Virus Replication in Cell Cultures
Authors : Juan G. Díaz Ochoa, Andreas Voigt, Heiko Briesen, Kai Sundmacher
Published in: Complex Sciences
Publisher: Springer Berlin Heidelberg
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We present in this report a stochastic model for the virus replication of influenza A in a cell culture. We consider not only the infection process of individual cells but also the number of intracellular components expressed in virus equivalent. Given that this expression is non constant in time we suggest a variable threshold, related to a viral resistance in the cell population, that could explain the time variation in the viral expression in the cell seen in experiments.