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2018 | OriginalPaper | Chapter

4. Translational Clinical Applications of Micro-/Nanoimaging Probes: Challenges and Perspectives

Authors : Senmin Wu, Hui Zhu, Jianle Huang, Kai Chen, Yan Yang, Chunpeng Zou, Zhe Liu

Published in: Advances in Functional Micro-/Nanoimaging Probes

Publisher: Springer Singapore

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Abstract

With the upgraded innovations in material science and translational medicine, micro-/nanoimaging probes show great promises for clinical translations to serve human healthcare. A number of micro-/nanoimaging probes have been approved for clinical imaging in US, CT, PET, SPECT, etc., and tremendous agents are at the status of clinical trials or under translations. This chapter focuses on the current commercially available imaging probes and their biomedical roles in disease diagnosis for patients. The potential challenges and future perspectives of imaging probes under evaluation are also briefly disclosed.

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Literature
1.
go back to reference Kurup, N., Naik, P.: Microbubbles: a novel delivery system. Asian J. Pharm. Res. Healthc. 2, 228 (2013) Kurup, N., Naik, P.: Microbubbles: a novel delivery system. Asian J. Pharm. Res. Healthc. 2, 228 (2013)
2.
go back to reference Hitesh, J., Parth, P., Suraj, F., Prachi, P., Shikha, Y.: Microbubbles-a potential ultrasound tool in drug delivery. Asian J. Pharm. Clin. Res. 4, 6–11 (2011) Hitesh, J., Parth, P., Suraj, F., Prachi, P., Shikha, Y.: Microbubbles-a potential ultrasound tool in drug delivery. Asian J. Pharm. Clin. Res. 4, 6–11 (2011)
3.
go back to reference Patel, R.M.: Microbubble: an ultrasound contrast agent in molecular imaging. Pharma Times 40, 15–19 (2008) Patel, R.M.: Microbubble: an ultrasound contrast agent in molecular imaging. Pharma Times 40, 15–19 (2008)
4.
go back to reference Palekar-Shanbhag, P., Chogale, M.M., Jog, S.V., Gaikwad, S.S.: Microbubbles and their applications in pharmaceutical targeting. Curr. Drug Deliv. 10, 363–373 (2013)CrossRef Palekar-Shanbhag, P., Chogale, M.M., Jog, S.V., Gaikwad, S.S.: Microbubbles and their applications in pharmaceutical targeting. Curr. Drug Deliv. 10, 363–373 (2013)CrossRef
5.
go back to reference Ittrich, H., Peldschus, K., Raabe, N., Kaul, M., Adam, G.: Superparamagnetic iron oxide nanoparticles in biomedicine: Applications and developments in diagnostics and therapy. RoFo: Fortschritte auf dem Gebiete der Roentgenstrahlen und der Nuklearmedizin 185, 1149–1166 (2013)CrossRef Ittrich, H., Peldschus, K., Raabe, N., Kaul, M., Adam, G.: Superparamagnetic iron oxide nanoparticles in biomedicine: Applications and developments in diagnostics and therapy. RoFo: Fortschritte auf dem Gebiete der Roentgenstrahlen und der Nuklearmedizin 185, 1149–1166 (2013)CrossRef
6.
go back to reference Lee, N., Choi, S.H., Hyeon, T.: Nano-sized ct contrast agents. Adv. Mater. 25, 2641–2660 (2013)CrossRef Lee, N., Choi, S.H., Hyeon, T.: Nano-sized ct contrast agents. Adv. Mater. 25, 2641–2660 (2013)CrossRef
7.
go back to reference Bean, C.P., Livingston, J.D.: Superparamagnetism. J. Appl. Phys. 30, S120–S129 (1959)CrossRef Bean, C.P., Livingston, J.D.: Superparamagnetism. J. Appl. Phys. 30, S120–S129 (1959)CrossRef
8.
go back to reference Schoonman, J.: Nanostructured materials in solid state ionics. Solid State Ionics 135, 5–19 (2000)CrossRef Schoonman, J.: Nanostructured materials in solid state ionics. Solid State Ionics 135, 5–19 (2000)CrossRef
9.
go back to reference Kemsheadl, J.T., Ugelstad, J.: Magnetic separation techniques: their application to medicine. Mol. Cell. Biochem. 67, 11–18 (1985)CrossRef Kemsheadl, J.T., Ugelstad, J.: Magnetic separation techniques: their application to medicine. Mol. Cell. Biochem. 67, 11–18 (1985)CrossRef
10.
go back to reference Hemmingsson, A., Carlsten, J., Ericsson, A., Klaveness, J., Sperber, G.O., Thuomas, K.A.: Relaxation enhancement of the dog liver and spleen by biodegradable superparamagnetic particles in proton magnetic resonance imaging. Acta Radiol. 28, 703–705 (1987)CrossRef Hemmingsson, A., Carlsten, J., Ericsson, A., Klaveness, J., Sperber, G.O., Thuomas, K.A.: Relaxation enhancement of the dog liver and spleen by biodegradable superparamagnetic particles in proton magnetic resonance imaging. Acta Radiol. 28, 703–705 (1987)CrossRef
11.
go back to reference Josephson, L., Lewis, J., Jacobs, P., Hahn, P.F., Stark, D.D.: The Effects of Iron Oxides on Proton Relaxivity. Prentice-Hall (1988) Josephson, L., Lewis, J., Jacobs, P., Hahn, P.F., Stark, D.D.: The Effects of Iron Oxides on Proton Relaxivity. Prentice-Hall (1988)
12.
go back to reference Rubin, G.D., Rofsky, N.M.: CT and MR Angiography: Comprehensive Vascular Assessment. Lippincott Williams & Wilkins (2008) Rubin, G.D., Rofsky, N.M.: CT and MR Angiography: Comprehensive Vascular Assessment. Lippincott Williams & Wilkins (2008)
13.
go back to reference Molinari, F., Fink, C., Risse, F., Tuengerthal, S., Bonomo, L., Kauczor, H.U.: Assessment of differential pulmonary blood flow using perfusion magnetic resonance imaging: comparison with radionuclide perfusion scintigraphy. Invest. Radiol. 41, 624 (2006)CrossRef Molinari, F., Fink, C., Risse, F., Tuengerthal, S., Bonomo, L., Kauczor, H.U.: Assessment of differential pulmonary blood flow using perfusion magnetic resonance imaging: comparison with radionuclide perfusion scintigraphy. Invest. Radiol. 41, 624 (2006)CrossRef
14.
go back to reference Ohno, Y., Hatabu, H., Higashino, T., Takenaka, D., Watanabe, H., Nishimura, Y., Yoshimura, M., Sugimura, K.: Dynamic perfusion MRI versus perfusion scintigraphy: prediction of postoperative lung function in patients with lung cancer. Am. J. Roentgenol. 182, 73–78 (2004)CrossRef Ohno, Y., Hatabu, H., Higashino, T., Takenaka, D., Watanabe, H., Nishimura, Y., Yoshimura, M., Sugimura, K.: Dynamic perfusion MRI versus perfusion scintigraphy: prediction of postoperative lung function in patients with lung cancer. Am. J. Roentgenol. 182, 73–78 (2004)CrossRef
15.
go back to reference Iwasawa, T., Saito, K., Ogawa, N., Ishiwa, N., Kurihara, H.: Prediction of postoperative pulmonary function using perfusion magnetic resonance imaging of the lung. J. Magn. Reson. Imaging 15, 685–692 (2002)CrossRef Iwasawa, T., Saito, K., Ogawa, N., Ishiwa, N., Kurihara, H.: Prediction of postoperative pulmonary function using perfusion magnetic resonance imaging of the lung. J. Magn. Reson. Imaging 15, 685–692 (2002)CrossRef
16.
go back to reference Weinsaft, J.W., Klem, I., Judd, R.M.: MRI for the assessment of myocardial viability. Cardiol. Clin. 25, 505–525 (2007)CrossRef Weinsaft, J.W., Klem, I., Judd, R.M.: MRI for the assessment of myocardial viability. Cardiol. Clin. 25, 505–525 (2007)CrossRef
17.
go back to reference Sakuma, H.: Magnetic resonance imaging for ischemic heart disease. J. Magn. Reson. Imaging 26, 3–13 (2007)CrossRef Sakuma, H.: Magnetic resonance imaging for ischemic heart disease. J. Magn. Reson. Imaging 26, 3–13 (2007)CrossRef
18.
go back to reference Saslow, D., Harms, S., Leach, M.O., Morris, E., Pisano, E., Sener, S.: American cancer society guidelines for breast screening with MRI as an adjunct to mammography. CA-A Cancer J. Clin. 57, 75 (2007)CrossRef Saslow, D., Harms, S., Leach, M.O., Morris, E., Pisano, E., Sener, S.: American cancer society guidelines for breast screening with MRI as an adjunct to mammography. CA-A Cancer J. Clin. 57, 75 (2007)CrossRef
19.
go back to reference Moon, M., Cornfeld, D., Weinreb, J.: Dynamic contrast-enhanced breast MR imaging. Magn. Reson. Imaging Clin. N. Am. 17, 351–362 (2009)CrossRef Moon, M., Cornfeld, D., Weinreb, J.: Dynamic contrast-enhanced breast MR imaging. Magn. Reson. Imaging Clin. N. Am. 17, 351–362 (2009)CrossRef
20.
go back to reference Fidler, J.: MR imaging of the small bowel. Radiographics 29, 1811–1825 (2009)CrossRef Fidler, J.: MR imaging of the small bowel. Radiographics 29, 1811–1825 (2009)CrossRef
21.
go back to reference Schneider, G., Reimer, P., Mamann, A., Kirchin, M.A., Morana, G., Grazioli, L.: Contrast agents in abdominal imaging: current and future directions. Topics Magn. Reson. Imaging 16, 107–124 (2005)CrossRef Schneider, G., Reimer, P., Mamann, A., Kirchin, M.A., Morana, G., Grazioli, L.: Contrast agents in abdominal imaging: current and future directions. Topics Magn. Reson. Imaging 16, 107–124 (2005)CrossRef
22.
go back to reference Hricak, H., Chen, M., Coakley, F.V., Kinkel, K., Yu, K.K., Sica, G., Bacchetti, P., Powell, C.B.: Complex adnexal masses: detection and characterization with MR imaging–multivariate analysis. Radiology 214, 39 (2000)CrossRef Hricak, H., Chen, M., Coakley, F.V., Kinkel, K., Yu, K.K., Sica, G., Bacchetti, P., Powell, C.B.: Complex adnexal masses: detection and characterization with MR imaging–multivariate analysis. Radiology 214, 39 (2000)CrossRef
23.
go back to reference Whitten, C.R., Desouza, N.M.: Magnetic resonance imaging of uterine malignancies. Topics Magn. Reson. Imaging. 17, 365–377 (2006)CrossRef Whitten, C.R., Desouza, N.M.: Magnetic resonance imaging of uterine malignancies. Topics Magn. Reson. Imaging. 17, 365–377 (2006)CrossRef
24.
go back to reference Manfredi, R., Gui, B., Maresca, G., Fanfani, F., Bonomo, L.: Endometrial cancer: magnetic resonance imaging. Abdom. Imaging 30, 626–636 (2005)CrossRef Manfredi, R., Gui, B., Maresca, G., Fanfani, F., Bonomo, L.: Endometrial cancer: magnetic resonance imaging. Abdom. Imaging 30, 626–636 (2005)CrossRef
25.
go back to reference Sohaib, S.A., Sahdev, A., Van, T.P., Jacobs, I.J., Reznek, R.H.: Characterization of adnexal mass lesions on MR imaging. Am. J. Roentgenol. 180, 1297–1304 (2003)CrossRef Sohaib, S.A., Sahdev, A., Van, T.P., Jacobs, I.J., Reznek, R.H.: Characterization of adnexal mass lesions on MR imaging. Am. J. Roentgenol. 180, 1297–1304 (2003)CrossRef
26.
go back to reference Calero, M., Gutierrez, L., Salas, G., Luengo, Y., Lazaro, A., Acedo, P., Morales, M.P., Miranda, R., Villanueva, A.: Efficient and safe internalization of magnetic iron oxide nanoparticles: Two fundamental requirements for biomedical applications. Nanomed. Nanotech. Biol. Med. 10, 733–743 (2014)CrossRef Calero, M., Gutierrez, L., Salas, G., Luengo, Y., Lazaro, A., Acedo, P., Morales, M.P., Miranda, R., Villanueva, A.: Efficient and safe internalization of magnetic iron oxide nanoparticles: Two fundamental requirements for biomedical applications. Nanomed. Nanotech. Biol. Med. 10, 733–743 (2014)CrossRef
27.
go back to reference Weissleder, R., Elizondo, G., Wittenberg, J., Lee, A.S., Josephson, L., Brady, T.J.: Ultrasmall superparamagnetic iron oxide: an intravenous contrast agent for assessing lymph nodes with MR imaging. Radiology 175, 494–498 (1990)CrossRef Weissleder, R., Elizondo, G., Wittenberg, J., Lee, A.S., Josephson, L., Brady, T.J.: Ultrasmall superparamagnetic iron oxide: an intravenous contrast agent for assessing lymph nodes with MR imaging. Radiology 175, 494–498 (1990)CrossRef
28.
go back to reference Seneterre, E., Weissleder, R., Jaramillo, D., Reimer, P., Lee, A.S., Brady, T.J., Wittenberg, J.: Bone marrow: ultrasmall superparamagnetic iron oxide for MR imaging. Radiology 179, 529 (1991)CrossRef Seneterre, E., Weissleder, R., Jaramillo, D., Reimer, P., Lee, A.S., Brady, T.J., Wittenberg, J.: Bone marrow: ultrasmall superparamagnetic iron oxide for MR imaging. Radiology 179, 529 (1991)CrossRef
29.
go back to reference Schmitz, S.A., Winterhalter, S., Schiffler, S., Gust, R., Wagner, S., Kresse, M., Coupland, S.E., Semmler, W., Wolf, K.J.: Uspio-enhanced direct MR imaging of thrombus: preclinical evaluation in rabbits. Radiology 221, 237 (2001)CrossRef Schmitz, S.A., Winterhalter, S., Schiffler, S., Gust, R., Wagner, S., Kresse, M., Coupland, S.E., Semmler, W., Wolf, K.J.: Uspio-enhanced direct MR imaging of thrombus: preclinical evaluation in rabbits. Radiology 221, 237 (2001)CrossRef
30.
go back to reference Schmitz, S.A., Coupland, S.E., Gust, R., Winterhalter, S., Wagner, S., Kresse, M., Semmler, W., Wolf, K.J.: Superparamagnetic iron oxide-enhanced MRI of atherosclerotic plaques in watanabe hereditable hyperlipidemic rabbits. Invest. Radiol. 35, 460–471 (2000)CrossRef Schmitz, S.A., Coupland, S.E., Gust, R., Winterhalter, S., Wagner, S., Kresse, M., Semmler, W., Wolf, K.J.: Superparamagnetic iron oxide-enhanced MRI of atherosclerotic plaques in watanabe hereditable hyperlipidemic rabbits. Invest. Radiol. 35, 460–471 (2000)CrossRef
31.
go back to reference Hahn, P.F., Stark, D.D., Weissleder, R., Elizondo, G., Saini, S., Ferrucci, J.T.: Clinical application of superparamagnetic iron oxide to MR imaging of tissue perfusion in vascular liver tumors. Radiology 174, 361–366 (1990)CrossRef Hahn, P.F., Stark, D.D., Weissleder, R., Elizondo, G., Saini, S., Ferrucci, J.T.: Clinical application of superparamagnetic iron oxide to MR imaging of tissue perfusion in vascular liver tumors. Radiology 174, 361–366 (1990)CrossRef
32.
go back to reference Kent, T.A., Quast, M.J., Kaplan, B.J., Lifsey, R.S., Eisenberg, H.M.: Assessment of a superparamagnetic iron oxide (AMI-25) as a brain contrast agent. Magn. Reson. Med. 13, 434–443 (1990)CrossRef Kent, T.A., Quast, M.J., Kaplan, B.J., Lifsey, R.S., Eisenberg, H.M.: Assessment of a superparamagnetic iron oxide (AMI-25) as a brain contrast agent. Magn. Reson. Med. 13, 434–443 (1990)CrossRef
33.
go back to reference Vellinga, M.M., Oude, E., Seewann, A., Pouwels, P., Wattjes, P., van der Pol, S.M., Pering, C., Polman, C., de Vries, H., Geurts, J., Barkhof, F.: Pluriformity of inflammation in multiple sclerosis shown by ultra-small iron oxide particle enhancement. Brain 131, 800–807 (2008)CrossRef Vellinga, M.M., Oude, E., Seewann, A., Pouwels, P., Wattjes, P., van der Pol, S.M., Pering, C., Polman, C., de Vries, H., Geurts, J., Barkhof, F.: Pluriformity of inflammation in multiple sclerosis shown by ultra-small iron oxide particle enhancement. Brain 131, 800–807 (2008)CrossRef
34.
go back to reference Ferrucci, J.T., Stark, D.D.: Iron oxide-enhanced mr imaging of the liver and spleen: review of the first 5 years. Am. J. Roentgenol. 155, 943–950 (1990)CrossRef Ferrucci, J.T., Stark, D.D.: Iron oxide-enhanced mr imaging of the liver and spleen: review of the first 5 years. Am. J. Roentgenol. 155, 943–950 (1990)CrossRef
35.
go back to reference Imai, Y., Murakami, T., Yoshida, S., Nishikawa, M., Ohsawa, M., Tokunaga, K., Murata, M., Shibata, K., Zushi, S., Kurokawa, M.: Superparamagnetic iron oxide–enhanced magnetic resonance images of hepatocellular carcinoma: correlation with histological grading. Hepatology 32, 205–212 (2000)CrossRef Imai, Y., Murakami, T., Yoshida, S., Nishikawa, M., Ohsawa, M., Tokunaga, K., Murata, M., Shibata, K., Zushi, S., Kurokawa, M.: Superparamagnetic iron oxide–enhanced magnetic resonance images of hepatocellular carcinoma: correlation with histological grading. Hepatology 32, 205–212 (2000)CrossRef
36.
go back to reference Pultrum, B.B., Ej, V.D.J., van Westreenen, H.L., van Dullemen, H.M., Kappert, P., Groen, H., Sietsma, J., Oudkerk, M., Plukker, J.T., van Dam, G.M.: Detection of lymph node metastases with ultrasmall superparamagnetic iron oxide (USPIO)-enhanced magnetic resonance imaging in oesophageal cancer: a feasibility study. Cancer Imaging 9, 19–28 (2009)CrossRef Pultrum, B.B., Ej, V.D.J., van Westreenen, H.L., van Dullemen, H.M., Kappert, P., Groen, H., Sietsma, J., Oudkerk, M., Plukker, J.T., van Dam, G.M.: Detection of lymph node metastases with ultrasmall superparamagnetic iron oxide (USPIO)-enhanced magnetic resonance imaging in oesophageal cancer: a feasibility study. Cancer Imaging 9, 19–28 (2009)CrossRef
37.
go back to reference Nguyen, B.C., Stanford, W., Thompson, B.H., Rossi, N.P., Kernstine, K.H., Kern, J.A., Robinson, R.A., Amorosa, J.K., Mammone, J.F., Outwater, E.K.: Multicenter clinical trial of ultrasmall superparamagnetic iron oxide in the evaluation of mediastinal lymph nodes in patients with primary lung carcinoma. J. Magn. Reson. Imaging 10, 468–473 (1999)CrossRef Nguyen, B.C., Stanford, W., Thompson, B.H., Rossi, N.P., Kernstine, K.H., Kern, J.A., Robinson, R.A., Amorosa, J.K., Mammone, J.F., Outwater, E.K.: Multicenter clinical trial of ultrasmall superparamagnetic iron oxide in the evaluation of mediastinal lymph nodes in patients with primary lung carcinoma. J. Magn. Reson. Imaging 10, 468–473 (1999)CrossRef
38.
go back to reference Tokuhara, T., Tanigawa, N., Matsuki, M., Nomura, E., Mabuchi, H., Lee, S.W., Tatsumi, Y., Nishimura, H., Yoshinaka, R., Kurisu, Y.: Evaluation of lymph node metastases in gastric cancer using magnetic resonance imaging with ultrasmall superparamagnetic iron oxide (USPIO): diagnostic performance in post-contrast images using new diagnostic criteria. Gastric Cancer 11, 194–200 (2008)CrossRef Tokuhara, T., Tanigawa, N., Matsuki, M., Nomura, E., Mabuchi, H., Lee, S.W., Tatsumi, Y., Nishimura, H., Yoshinaka, R., Kurisu, Y.: Evaluation of lymph node metastases in gastric cancer using magnetic resonance imaging with ultrasmall superparamagnetic iron oxide (USPIO): diagnostic performance in post-contrast images using new diagnostic criteria. Gastric Cancer 11, 194–200 (2008)CrossRef
39.
go back to reference Ruehm, S.G., Corot, C., Vogt, P., Kolb, S., Debatin, J.F.: Magnetic resonance imaging of atherosclerotic plaque with ultrasmall superparamagnetic particles of iron oxide in hyperlipidemic rabbits. Circulation 103, 415 (2001)CrossRef Ruehm, S.G., Corot, C., Vogt, P., Kolb, S., Debatin, J.F.: Magnetic resonance imaging of atherosclerotic plaque with ultrasmall superparamagnetic particles of iron oxide in hyperlipidemic rabbits. Circulation 103, 415 (2001)CrossRef
40.
go back to reference Kooi, M.E., Cappendijk, V.C., Cleutjens, K.B., Kessels, A.G., Kitslaar, P.J., Borgers, M., Frederik, P.M., Daemen, M.J., van Engelshoven, J.M.: Accumulation of ultrasmall superparamagnetic particles of iron oxide in human atherosclerotic plaques can be detected by in vivo magnetic resonance imaging. Circulation 107, 2453–2458 (2003)CrossRef Kooi, M.E., Cappendijk, V.C., Cleutjens, K.B., Kessels, A.G., Kitslaar, P.J., Borgers, M., Frederik, P.M., Daemen, M.J., van Engelshoven, J.M.: Accumulation of ultrasmall superparamagnetic particles of iron oxide in human atherosclerotic plaques can be detected by in vivo magnetic resonance imaging. Circulation 107, 2453–2458 (2003)CrossRef
41.
go back to reference Hahn, P.F., Stark, D.D., Ferrucci, J.T.: Accumulation of iron oxide particles around liver metastases during MR imaging. Gastrointest. Radiol. 17, 173–174 (1992)CrossRef Hahn, P.F., Stark, D.D., Ferrucci, J.T.: Accumulation of iron oxide particles around liver metastases during MR imaging. Gastrointest. Radiol. 17, 173–174 (1992)CrossRef
42.
go back to reference Moore, A., Marecos, E., Bogdanov Jr., A., Weissleder, R.: Tumoral distribution of long-circulating dextran-coated iron oxide nanoparticles in a rodent model. Radiology 214, 568–574 (2000)CrossRef Moore, A., Marecos, E., Bogdanov Jr., A., Weissleder, R.: Tumoral distribution of long-circulating dextran-coated iron oxide nanoparticles in a rodent model. Radiology 214, 568–574 (2000)CrossRef
43.
go back to reference Saleh, A., Schroeter, M., Jonkmanns, C., Hartung, H.P., Modder, U., Jander, S.: In vivo MRI of brain inflammation in human ischaemic stroke. Brain 127, 1670–1677 (2004)CrossRef Saleh, A., Schroeter, M., Jonkmanns, C., Hartung, H.P., Modder, U., Jander, S.: In vivo MRI of brain inflammation in human ischaemic stroke. Brain 127, 1670–1677 (2004)CrossRef
44.
go back to reference Enochs, W.S., Harsh, G., Hochberg, F., Weissleder, R.: Improved delineation of human brain tumors on mr images using a long-circulating, superparamagnetic iron oxide agent. J. Magn. Reson. Imaging 9, 228–232 (1999)CrossRef Enochs, W.S., Harsh, G., Hochberg, F., Weissleder, R.: Improved delineation of human brain tumors on mr images using a long-circulating, superparamagnetic iron oxide agent. J. Magn. Reson. Imaging 9, 228–232 (1999)CrossRef
45.
go back to reference Eniola, A.O., Willcox, P.J., Hammer, D.A.: Interplay between rolling and firm adhesion elucidated with a cell-free system engineered with two distinct receptor-ligand pairs. Biophys. J. 85, 2720–2731 (2003)CrossRef Eniola, A.O., Willcox, P.J., Hammer, D.A.: Interplay between rolling and firm adhesion elucidated with a cell-free system engineered with two distinct receptor-ligand pairs. Biophys. J. 85, 2720–2731 (2003)CrossRef
46.
go back to reference Liu, Y., Miyoshi, H., Nakamura, M.: Encapsulated ultrasound microbubbles: therapeutic application in drug/gene delivery. J. Control. Release 114, 89–99 (2006)CrossRef Liu, Y., Miyoshi, H., Nakamura, M.: Encapsulated ultrasound microbubbles: therapeutic application in drug/gene delivery. J. Control. Release 114, 89–99 (2006)CrossRef
47.
go back to reference Amberg, J.R., Thompson, W.M., Golberger, L., Williamson, S., Alexander, R., Bates, M.: Factors in the intestinal absorption of oral cholecystopaques. Invest. Radiol. 15, S136 (1980)CrossRef Amberg, J.R., Thompson, W.M., Golberger, L., Williamson, S., Alexander, R., Bates, M.: Factors in the intestinal absorption of oral cholecystopaques. Invest. Radiol. 15, S136 (1980)CrossRef
48.
go back to reference Berk, R.N., Loeb, P.M.: Pharmacology and physiology of the biliary radiographic contrast materials. Semin. Roentgenol. 11, 147–156 (1976)CrossRef Berk, R.N., Loeb, P.M.: Pharmacology and physiology of the biliary radiographic contrast materials. Semin. Roentgenol. 11, 147–156 (1976)CrossRef
49.
go back to reference Berk, R.N., Loeb, P.M., Cobo-Frenkel, A., Barnhart, J.L.: The biliary and urinary excretion of sodium tyropanoate and sodium ipodate in dogs: Pharmacokinetics, influence of bile salts and choleretic effects with comparison to iopanoic acid. Invest. Radiol. 12, 85 (1977)CrossRef Berk, R.N., Loeb, P.M., Cobo-Frenkel, A., Barnhart, J.L.: The biliary and urinary excretion of sodium tyropanoate and sodium ipodate in dogs: Pharmacokinetics, influence of bile salts and choleretic effects with comparison to iopanoic acid. Invest. Radiol. 12, 85 (1977)CrossRef
50.
go back to reference Janes, J.O., Dietschy, J.M., Berk, R.N., Loeb, P.M., Barnhart, J.L.: Determinants of the rate of intestinal absorption of oral cholecystographic contrast agents in the dog jejunum. Gastroenterology 76, 970–977 (1979) Janes, J.O., Dietschy, J.M., Berk, R.N., Loeb, P.M., Barnhart, J.L.: Determinants of the rate of intestinal absorption of oral cholecystographic contrast agents in the dog jejunum. Gastroenterology 76, 970–977 (1979)
51.
go back to reference Chilton, C., Swanson, D., Chilton, H., Thrall, J.: Pharmaceuticals in Medical Imaging. Macmillan Publishing Co. (1990) Chilton, C., Swanson, D., Chilton, H., Thrall, J.: Pharmaceuticals in Medical Imaging. Macmillan Publishing Co. (1990)
52.
go back to reference Sovak, M., Hoey, G.B., Smith, K.R.: Radiocontrast agents. Handb. Exp. Pharmacol. 73, 1–125 (1984)CrossRef Sovak, M., Hoey, G.B., Smith, K.R.: Radiocontrast agents. Handb. Exp. Pharmacol. 73, 1–125 (1984)CrossRef
53.
go back to reference Dawson, P., Cosgrove, D.O., Grainger, R.G.: Textbook of Contrast Media. Isis Medical Media, Calif (1999) Dawson, P., Cosgrove, D.O., Grainger, R.G.: Textbook of Contrast Media. Isis Medical Media, Calif (1999)
54.
go back to reference Siegel, R.L., Miller, K.D., Jemal, A.: Cancer statistics, 2015. CA Cancer J. Clin. 65, 5–29 (2015)CrossRef Siegel, R.L., Miller, K.D., Jemal, A.: Cancer statistics, 2015. CA Cancer J. Clin. 65, 5–29 (2015)CrossRef
55.
go back to reference Talbot, J.N., Fartoux, L., Balogova, S., Nataf, V., Kerrou, K., Gutman, F., Huchet, V., Ancel, D., Grange, J.D., Rosmorduc, O.: Detection of hepatocellular carcinoma with PET/CT: a prospective comparison of 18F-fluorocholine and 18F-FDG in patients with cirrhosis or chronic liver disease. J. Nucl. Med. 51, 1699–1706 (2010)CrossRef Talbot, J.N., Fartoux, L., Balogova, S., Nataf, V., Kerrou, K., Gutman, F., Huchet, V., Ancel, D., Grange, J.D., Rosmorduc, O.: Detection of hepatocellular carcinoma with PET/CT: a prospective comparison of 18F-fluorocholine and 18F-FDG in patients with cirrhosis or chronic liver disease. J. Nucl. Med. 51, 1699–1706 (2010)CrossRef
56.
go back to reference How, K.N., Dugue, A.E., Sevin, E., Allouache, N., Lesaunier, F., Joly, F., Aide, N.: Pairwise comparison of 18F-FDG and 18F-FCH PET/CT in prostate cancer patients with rising PSA and known or suspected second malignancy. Nucl. Med. Commun. 37, 348–355 (2016)CrossRef How, K.N., Dugue, A.E., Sevin, E., Allouache, N., Lesaunier, F., Joly, F., Aide, N.: Pairwise comparison of 18F-FDG and 18F-FCH PET/CT in prostate cancer patients with rising PSA and known or suspected second malignancy. Nucl. Med. Commun. 37, 348–355 (2016)CrossRef
57.
go back to reference Garcia, V., Jimenez, A., Villena, M., Jimenez, L., Borras, M.: 18F-fluorocholine PET/CT, brain MRI, and 5-aminolevulinic acid for the assessment of tumor resection in high-grade glioma. Clin. Nucl. Med. 42, e300–e303 (2017)CrossRef Garcia, V., Jimenez, A., Villena, M., Jimenez, L., Borras, M.: 18F-fluorocholine PET/CT, brain MRI, and 5-aminolevulinic acid for the assessment of tumor resection in high-grade glioma. Clin. Nucl. Med. 42, e300–e303 (2017)CrossRef
58.
go back to reference Balogova, S., Huchet, V., Kerrou, K., Nataf, V., Gutman, F., Antoine, M., Ruppert, A., Prignon, A., Lavolee, A., Montravers, F., Mayaud, C., Cadranel, J., Talbot, J.: Detection of bronchioloalveolar cancer by means of PET/CT and 18F-fluorocholine, and comparison with 18F-fluorodeoxyglucose. Nucl. Med. Commun. 31, 389–397 (2010) Balogova, S., Huchet, V., Kerrou, K., Nataf, V., Gutman, F., Antoine, M., Ruppert, A., Prignon, A., Lavolee, A., Montravers, F., Mayaud, C., Cadranel, J., Talbot, J.: Detection of bronchioloalveolar cancer by means of PET/CT and 18F-fluorocholine, and comparison with 18F-fluorodeoxyglucose. Nucl. Med. Commun. 31, 389–397 (2010)
59.
go back to reference Are, C., Meyer, B., Stack, A., Ahmad, H., Smith, L., Qian, B., Song, T., Chowdhury, S.: Global trends in the burden of liver cancer. J. Surg. Oncol. 115, 591–602 (2017)CrossRef Are, C., Meyer, B., Stack, A., Ahmad, H., Smith, L., Qian, B., Song, T., Chowdhury, S.: Global trends in the burden of liver cancer. J. Surg. Oncol. 115, 591–602 (2017)CrossRef
60.
go back to reference Kubota, R., Kubota, K., Yamada, S., Tada, M., Takahashi, T., Iwata, R., Tamahashi, N.: Methionine uptake by tumor tissue: a microautoradiographic comparison with FDG. J. Nucl. Med. 36, 484–492 (1995) Kubota, R., Kubota, K., Yamada, S., Tada, M., Takahashi, T., Iwata, R., Tamahashi, N.: Methionine uptake by tumor tissue: a microautoradiographic comparison with FDG. J. Nucl. Med. 36, 484–492 (1995)
61.
go back to reference Buroni, F.E., Pasi, F., Persico, M.G., Lodola, L., Aprile, C., Nano, R.: Evidence of 18F-FCH uptake in human T98G glioblastoma cells. Anticancer Res. 35, 6439–6443 (2015) Buroni, F.E., Pasi, F., Persico, M.G., Lodola, L., Aprile, C., Nano, R.: Evidence of 18F-FCH uptake in human T98G glioblastoma cells. Anticancer Res. 35, 6439–6443 (2015)
62.
go back to reference Bejanin, A., Schonhaut, D.R., La Joie, R., Kramer, J.H., Baker, S.L., Sosa, N., Ayakta, N., Cantwell, A., Janabi, M., Lauriola, M., O’Neil, J.P., Gorno-Tempini, M.L., Miller, Z.A., Rosen, H.J., Miller, B.L., Jagust, W.J., Rabinovici, G.D.: Tau pathology and neurodegeneration contribute to cognitive impairment in alzheimer’s disease. Brain 140, 3286–3300 (2017)CrossRef Bejanin, A., Schonhaut, D.R., La Joie, R., Kramer, J.H., Baker, S.L., Sosa, N., Ayakta, N., Cantwell, A., Janabi, M., Lauriola, M., O’Neil, J.P., Gorno-Tempini, M.L., Miller, Z.A., Rosen, H.J., Miller, B.L., Jagust, W.J., Rabinovici, G.D.: Tau pathology and neurodegeneration contribute to cognitive impairment in alzheimer’s disease. Brain 140, 3286–3300 (2017)CrossRef
63.
go back to reference Kang, J.M., Lee, S.Y., Seo, S., Jeong, H.J., Woo, S.H., Lee, H., Lee, Y.B., Yeon, B.K., Shin, D.H., Park, K.H., Kang, H., Okamura, N., Furumoto, S., Yanai, K., Villemagne, V.L., Seong, J.K., Na, D.L., Ido, T., Cho, J., Lee, K.M., Noh, Y.: Tau positron emission tomography using [(18)F]THK5351 and cerebral glucose hypometabolism in alzheimer’s disease. Neurobiol. Aging 59, 210–219 (2017)CrossRef Kang, J.M., Lee, S.Y., Seo, S., Jeong, H.J., Woo, S.H., Lee, H., Lee, Y.B., Yeon, B.K., Shin, D.H., Park, K.H., Kang, H., Okamura, N., Furumoto, S., Yanai, K., Villemagne, V.L., Seong, J.K., Na, D.L., Ido, T., Cho, J., Lee, K.M., Noh, Y.: Tau positron emission tomography using [(18)F]THK5351 and cerebral glucose hypometabolism in alzheimer’s disease. Neurobiol. Aging 59, 210–219 (2017)CrossRef
64.
go back to reference Ueno, A., Masugi, Y., Yamazaki, K., Komuta, M., Effendi, K., Tanami, Y., Tsujikawa, H., Tanimoto, A., Okuda, S., Itano, O., Kitagawa, Y., Kuribayashi, S., Sakamoto, M.: OATP1B3 expression is strongly associated with Wnt/beta-catenin signalling and represents the transporter of gadoxetic acid in hepatocellular carcinoma. J. Hepatol. 61, 1080–1087 (2014)CrossRef Ueno, A., Masugi, Y., Yamazaki, K., Komuta, M., Effendi, K., Tanami, Y., Tsujikawa, H., Tanimoto, A., Okuda, S., Itano, O., Kitagawa, Y., Kuribayashi, S., Sakamoto, M.: OATP1B3 expression is strongly associated with Wnt/beta-catenin signalling and represents the transporter of gadoxetic acid in hepatocellular carcinoma. J. Hepatol. 61, 1080–1087 (2014)CrossRef
65.
go back to reference Junking, M., Grainok, J., Thepmalee, C., Wongkham, S., Yenchitsomanus, P.T.: Enhanced cytotoxic activity of effector T-cells against cholangiocarcinoma by dendritic cells pulsed with pooled mRNA. Tumour Biol. 39, 1010428317733367 (2017)CrossRef Junking, M., Grainok, J., Thepmalee, C., Wongkham, S., Yenchitsomanus, P.T.: Enhanced cytotoxic activity of effector T-cells against cholangiocarcinoma by dendritic cells pulsed with pooled mRNA. Tumour Biol. 39, 1010428317733367 (2017)CrossRef
66.
go back to reference Piert, M., Montgomery, J., Kunju, L.P., Siddiqui, J., Rogers, V., Rajendiran, T., Johnson, T.D., Shao, X., Davenport, M.S.: 18F-choline PET/MRI: The additional value of pet for MRI-guided transrectal prostate biopsies. J. Nucl. Med. 57, 1065–1070 (2016)CrossRef Piert, M., Montgomery, J., Kunju, L.P., Siddiqui, J., Rogers, V., Rajendiran, T., Johnson, T.D., Shao, X., Davenport, M.S.: 18F-choline PET/MRI: The additional value of pet for MRI-guided transrectal prostate biopsies. J. Nucl. Med. 57, 1065–1070 (2016)CrossRef
67.
go back to reference Tardy, I., Pochon, S., Theraulaz, M., Emmel, P., Passantino, L., Tranquart, F., Schneider, M.: Ultrasound molecular imaging of VEGFR2 in a rat prostate tumor model using BR55. Invest. Radiol. 45, 573–578 (2010)CrossRef Tardy, I., Pochon, S., Theraulaz, M., Emmel, P., Passantino, L., Tranquart, F., Schneider, M.: Ultrasound molecular imaging of VEGFR2 in a rat prostate tumor model using BR55. Invest. Radiol. 45, 573–578 (2010)CrossRef
Metadata
Title
Translational Clinical Applications of Micro-/Nanoimaging Probes: Challenges and Perspectives
Authors
Senmin Wu
Hui Zhu
Jianle Huang
Kai Chen
Yan Yang
Chunpeng Zou
Zhe Liu
Copyright Year
2018
Publisher
Springer Singapore
DOI
https://doi.org/10.1007/978-981-10-4804-3_4

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