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17-06-2024

Tuning sensitivity of bimetallic, MXene and graphene-based SPR biosensors for rapid malaria detection: a numerical approach

Authors: Bhishma Karki, Arun Uniyal, Manoj Sharma, Ram Bharos Yadav, Parusharamulu Buduma

Published in: Journal of Computational Electronics | Issue 4/2024

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Abstract

The potential of surface plasmon resonance (SPR) biosensors to detect different biomolecules quickly and sensitively has attracted much attention. In this work, we use a numerical method to identify malaria phases by exploring the sensitivity adjustment of SPR sensors based on bimetallic, MXene and graphene layers. Effective treatment for malaria, a potentially fatal disease brought on by plasmodium parasites, depends on early identification. Innovative biosensing technologies are necessary since traditional diagnostic procedures frequently lack sensitivity and speed. The transfer matrix method is employed here in this study for reflectance calculation. The COMSOL software finds the electric field distribution across the various layers interfaces. The maximum sensitivity of 301.1667°/RIU has been attained for the proposed work.

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Metadata
Title
Tuning sensitivity of bimetallic, MXene and graphene-based SPR biosensors for rapid malaria detection: a numerical approach
Authors
Bhishma Karki
Arun Uniyal
Manoj Sharma
Ram Bharos Yadav
Parusharamulu Buduma
Publication date
17-06-2024
Publisher
Springer US
Published in
Journal of Computational Electronics / Issue 4/2024
Print ISSN: 1569-8025
Electronic ISSN: 1572-8137
DOI
https://doi.org/10.1007/s10825-024-02191-4