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01.08.2013 | Research Article

Experimental characterization of powered Fontan hemodynamics in an idealized total cavopulmonary connection model

verfasst von: Anna-Elodie M. Kerlo, Yann T. Delorme, Duo Xu, Steven H. Frankel, Guruprasad A. Giridharan, Mark D. Rodefeld, Jun Chen

Erschienen in: Experiments in Fluids | Ausgabe 8/2013

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Abstract

A viscous impeller pump (VIP) based on the Von Karman viscous pump is specifically designed to provide cavopulmonary assist in a univentricular Fontan circulation. The technology will make it possible to biventricularize the univentricular Fontan circulation. Ideally, it will reduce the number of surgeries required for Fontan conversion from three to one early in life, while simultaneously improving physiological conditions. Later in life, it will provide a currently unavailable means of chronic support for adolescent and adult patients with failing Fontan circulations. Computational fluid dynamics simulations demonstrate that the VIP can satisfactorily augment cavopulmonary blood flow in an idealized total cavopulmonary connection (TCPC). When the VIP is deployed at the TCPC intersection as a static device, it stabilizes the four-way flow pattern and is not obstructive to the flow. Experimental studies are carried out to assess performance, hemodynamic characteristics, and flow structures of the VIP in an idealized TCPC model. Stereoscopic particle image velocimetry is applied using index-matched blood analog. Results show excellent performance of the VIP without cavitation and with reduction of the energy losses. The non-rotating VIP smoothes and accelerates flow, and decreases stresses and turbulence in the TCPC. The rotating VIP generates the desired low-pressure Fontan flow augmentation (0–10 mmHg) while maintaining acceptable stress thresholds.

Vorheriger Artikel A particle-tracking approach for accurate material derivative measurements with tomographic PIV

Nächster Artikel Hydraulic admittance of a partially saturated microfluidic slit

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Titel: Experimental characterization of powered Fontan hemodynamics in an idealized total cavopulmonary connection model
verfasst von: Anna-Elodie M. Kerlo
Yann T. Delorme
Duo Xu
Steven H. Frankel
Guruprasad A. Giridharan
Mark D. Rodefeld
Jun Chen
Publikationsdatum: 01.08.2013
Verlag: Springer Berlin Heidelberg
Erschienen in: Experiments in Fluids / Ausgabe 8/2013
Print ISSN: 0723-4864
Elektronische ISSN: 1432-1114
DOI: https://doi.org/10.1007/s00348-013-1581-8

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