Skip to main content
Erschienen in: KI - Künstliche Intelligenz 2/2015

01.06.2015 | Technical Contribution

Exploiting Latent Embeddings of Nominal Clinical Data for Predicting Hospital Readmission

verfasst von: Denis Krompaß, Cristóbal Esteban, Volker Tresp, Martin Sedlmayr, Thomas Ganslandt

Erschienen in: KI - Künstliche Intelligenz | Ausgabe 2/2015

Einloggen

Aktivieren Sie unsere intelligente Suche, um passende Fachinhalte oder Patente zu finden.

search-config
loading …

Abstract

Hospital readmissions of patients put a high burden not only on the health care system, but also on the patients since complications after discharge generally lead to additional burdens. Estimating the risk of readmission after discharge from inpatient care has been the subject of several publications in recent years. In those publications the authors mostly tried to directly infer the readmission risk (within a certain time frame) from the clinical data recorded in the medical routine such as primary diagnosis, co-morbidities, length of stay, or questionnaires. Instead of using these data directly as inputs for a prediction model, we are exploiting latent embeddings for the nominal parts of the data (e.g., diagnosis and procedure codes). These latent embeddings have been used with great success in the natural language processing domain and can be constructed in a preprocessing step. We show in our experiments, that a prediction model that exploits these latent embeddings can lead to improved readmission predictive models.

Sie haben noch keine Lizenz? Dann Informieren Sie sich jetzt über unsere Produkte:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

  • über 102.000 Bücher
  • über 537 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Maschinenbau + Werkstoffe
  • Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

KI - Künstliche Intelligenz

The Scientific journal "KI – Künstliche Intelligenz" is the official journal of the division for artificial intelligence within the "Gesellschaft für Informatik e.V." (GI) – the German Informatics Society - with constributions from troughout the field of artificial intelligence.

Springer Professional "Wirtschaft"

Online-Abonnement

Mit Springer Professional "Wirtschaft" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 340 Zeitschriften

aus folgenden Fachgebieten:

  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Versicherung + Risiko




Jetzt Wissensvorsprung sichern!

Weitere Produktempfehlungen anzeigen
Fußnoten
1
Admission and discharge reason, therapy (also medication) and department codes.
 
2
Primary diagnosis, secondary diagnosis, LOINC Lab, therapies/medication, admission reason, discharge reason and department codes.
 
Literatur
1.
Zurück zum Zitat Bengio Y, Ducharme R, Vincent P, Janvin C (2003) A neural probabilistic language model. J Mach Learn Res 3:1137–1155MATH Bengio Y, Ducharme R, Vincent P, Janvin C (2003) A neural probabilistic language model. J Mach Learn Res 3:1137–1155MATH
2.
Zurück zum Zitat Billings J, Blunt I, Stevenson A, Georghiou T, Lewis G, Bardsley M (2012) Development of a predictive model to identify inpatients at risk of readmission within 30 days of discharge (parr-30). BMJ Open Billings J, Blunt I, Stevenson A, Georghiou T, Lewis G, Bardsley M (2012) Development of a predictive model to identify inpatients at risk of readmission within 30 days of discharge (parr-30). BMJ Open
3.
Zurück zum Zitat Choudhry S, Li J, Davis D, Erdmann C, Sikka R, Sutariya B (2013) A public-private partnership develops and externally validates a 30-day hospital readmission risk prediction model. Online J Public Health Inform 5(2) Choudhry S, Li J, Davis D, Erdmann C, Sikka R, Sutariya B (2013) A public-private partnership develops and externally validates a 30-day hospital readmission risk prediction model. Online J Public Health Inform 5(2)
4.
Zurück zum Zitat Collobert R, Weston J, Bottou L, Karlen M, Kavukcuoglu K, Kuksa P (2011) Natural language processing (almost) from scratch. J Mach Learn Res 12:2493–2537MATH Collobert R, Weston J, Bottou L, Karlen M, Kavukcuoglu K, Kuksa P (2011) Natural language processing (almost) from scratch. J Mach Learn Res 12:2493–2537MATH
5.
Zurück zum Zitat Donzé J, Aujesky D, Williams D, Schnipper JL (2013) Potentially avoidable 30-day hospital readmissions in medical patients. JAMA 173:632–638 Donzé J, Aujesky D, Williams D, Schnipper JL (2013) Potentially avoidable 30-day hospital readmissions in medical patients. JAMA 173:632–638
6.
Zurück zum Zitat Dormann H, Neubert A, Criegee-Rieck M, Egger T, Radespiel-Troger M, Azaz-Livshits T, Levy M, Brune K, Hahn EG (2004) Readmissions and adverse drug reactions in internal medicine: the economic impact. J Int Med 255:653–663CrossRef Dormann H, Neubert A, Criegee-Rieck M, Egger T, Radespiel-Troger M, Azaz-Livshits T, Levy M, Brune K, Hahn EG (2004) Readmissions and adverse drug reactions in internal medicine: the economic impact. J Int Med 255:653–663CrossRef
7.
Zurück zum Zitat Hasan O, Meltzer DO, Shaykevich SA, Bell CM et al (2009) Hospital readmission in general medicine patients: a prediction model. J Gen Intern Med 25:211–219CrossRef Hasan O, Meltzer DO, Shaykevich SA, Bell CM et al (2009) Hospital readmission in general medicine patients: a prediction model. J Gen Intern Med 25:211–219CrossRef
8.
Zurück zum Zitat Hebert C, Shivade C, Foraker R, Wasserman J, et al (2014) Diagnosis-specific readmission risk prediction using electronic health data: A retrospective cohort study. BMC Med Inform Decis Making 14 Hebert C, Shivade C, Foraker R, Wasserman J, et al (2014) Diagnosis-specific readmission risk prediction using electronic health data: A retrospective cohort study. BMC Med Inform Decis Making 14
9.
Zurück zum Zitat Hendricks V, Schmidt S, Vogt A, Gysan D, Latz V, Schwang I, Griebenow R, Riedel R (2014) Case management program for patients with chronic heart failure. effectiveness in terms of mortality, hospital admissions and costs. Deutsches Aerzteblatt. International 111:264–270 Hendricks V, Schmidt S, Vogt A, Gysan D, Latz V, Schwang I, Griebenow R, Riedel R (2014) Case management program for patients with chronic heart failure. effectiveness in terms of mortality, hospital admissions and costs. Deutsches Aerzteblatt. International 111:264–270
10.
Zurück zum Zitat Huang EH, Socher R, Manning CD, Ng AY (2012) Improving word representations via global context and multiple word prototypes. In: Annual Meeting of the Association for Computational Linguistics (ACL) Huang EH, Socher R, Manning CD, Ng AY (2012) Improving word representations via global context and multiple word prototypes. In: Annual Meeting of the Association for Computational Linguistics (ACL)
11.
Zurück zum Zitat Jack BW, Chetty VK, Anthony D, Greenwald JL et al (1999) A reengineered hospital discharge program to decrease rehospitalization: a randomized trial. JAMA 281:613–620CrossRef Jack BW, Chetty VK, Anthony D, Greenwald JL et al (1999) A reengineered hospital discharge program to decrease rehospitalization: a randomized trial. JAMA 281:613–620CrossRef
12.
Zurück zum Zitat Jencks SF, Williams MV, Coleman EA New England Journal of Medicine 14:1418–1428 Jencks SF, Williams MV, Coleman EA New England Journal of Medicine 14:1418–1428
13.
Zurück zum Zitat Lebret R, Collobert R (2014) Word embeddings through hellinger pca. In: Proceedings of the 14th Conference of the European Chapter of the Association for Computational Linguistics (EACL). Association for Computational Linguistics. pp 482–490 Lebret R, Collobert R (2014) Word embeddings through hellinger pca. In: Proceedings of the 14th Conference of the European Chapter of the Association for Computational Linguistics (EACL). Association for Computational Linguistics. pp 482–490
14.
Zurück zum Zitat Naylor MD, Brooten D, Campbell R, Jacobsen BS et al (1999) A comprehensive discharge planning and home follow-up of hospitalized elders: a randomized clinical trial. JAMA 281:613–620CrossRef Naylor MD, Brooten D, Campbell R, Jacobsen BS et al (1999) A comprehensive discharge planning and home follow-up of hospitalized elders: a randomized clinical trial. JAMA 281:613–620CrossRef
15.
Zurück zum Zitat OECD (2013) Health at a glance 2013: OECD indicators. http://dx.doi.org/10.1787/health_glance-2013-en OECD (2013) Health at a glance 2013: OECD indicators. http://​dx.​doi.​org/​10.​1787/​health_​glance-2013-en
16.
Zurück zum Zitat Department of Health (2013) Payment by results guidance for 2013–2014. Department of Health, London Department of Health (2013) Payment by results guidance for 2013–2014. Department of Health, London
17.
Zurück zum Zitat Ohman E, Granger CB, Harrington RA, Lee KL (2000) Risk stratification and therapeutic decision making in acute coronary syndromes. JAMA 286(7):876–878CrossRef Ohman E, Granger CB, Harrington RA, Lee KL (2000) Risk stratification and therapeutic decision making in acute coronary syndromes. JAMA 286(7):876–878CrossRef
19.
Zurück zum Zitat Rümenapf G, Geiger S, Schneider B, Amendt K, Wilhelm N, Morbach S, Nagel N (2013) Readmissions of patients with diabetes mellitus and foot ulcers after infra-popliteal bypass surgery: attacking the problem by an integrated case management model. Eur J Vasc Med 42:56–67 Rümenapf G, Geiger S, Schneider B, Amendt K, Wilhelm N, Morbach S, Nagel N (2013) Readmissions of patients with diabetes mellitus and foot ulcers after infra-popliteal bypass surgery: attacking the problem by an integrated case management model. Eur J Vasc Med 42:56–67
20.
Zurück zum Zitat Smitht D, Giobbie-Hurder A, Weinberger M, Oddone EZ et al (2000) Predicting non-elective hospital readmissions: a multi site study. J Clin Epidemiol 53:1113–1118CrossRef Smitht D, Giobbie-Hurder A, Weinberger M, Oddone EZ et al (2000) Predicting non-elective hospital readmissions: a multi site study. J Clin Epidemiol 53:1113–1118CrossRef
21.
Zurück zum Zitat Srivastava N, Hinton G, Krizhevsky A, Sutskever I, Salakhutdinov R (2014) Dropout: a simple way to prevent neural networks from overfitting. J Mach Learn Res 15:1929–1958MATHMathSciNet Srivastava N, Hinton G, Krizhevsky A, Sutskever I, Salakhutdinov R (2014) Dropout: a simple way to prevent neural networks from overfitting. J Mach Learn Res 15:1929–1958MATHMathSciNet
22.
Zurück zum Zitat Turney PD, Pantel P (2010) From frequency to meaning: vector space models of semantics. pp 141–188 Turney PD, Pantel P (2010) From frequency to meaning: vector space models of semantics. pp 141–188
23.
Zurück zum Zitat Yu S, Van Esbroeck A, Farooq F, Fung G, Anand V, Krishnapuram B (2013) Predicting readmission risk with institution specific prediction models. In: ICHI, pp 415–420 Yu S, Van Esbroeck A, Farooq F, Fung G, Anand V, Krishnapuram B (2013) Predicting readmission risk with institution specific prediction models. In: ICHI, pp 415–420
Metadaten
Titel
Exploiting Latent Embeddings of Nominal Clinical Data for Predicting Hospital Readmission
verfasst von
Denis Krompaß
Cristóbal Esteban
Volker Tresp
Martin Sedlmayr
Thomas Ganslandt
Publikationsdatum
01.06.2015
Verlag
Springer Berlin Heidelberg
Erschienen in
KI - Künstliche Intelligenz / Ausgabe 2/2015
Print ISSN: 0933-1875
Elektronische ISSN: 1610-1987
DOI
https://doi.org/10.1007/s13218-014-0344-x

Weitere Artikel der Ausgabe 2/2015

KI - Künstliche Intelligenz 2/2015 Zur Ausgabe