The lack of on-line measurements of key variables is the main obstacle that hinders the development of proper control and optimisation systems for fermentation processes. This is especially true for solid substrate cultivation (SSC) that lags behind submerged cultivation. To partially overcome this limitation of SSC processes, on-line observers of relevant variables, such as biomass, secondary metabolites and nutrients concentration, can be developed. In fact, the high cost and scarcity of reliable sensors adapted to SSC systems forces the development of softsensors (software + sensors) .
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- Fungal biomass estimation in batch solid substrate cultivation using asymptotic observation
- Springer Netherlands