Blood system functions are very diverse and important for most processes in human organism. One of its primary functions is matter transport among different parts of the organism including tissue supplying with oxygen, carbon dioxide excretion, drug propagation etc. Forecasting of these processes under normal conditions and in the presence of different pathologies like atherosclerosis, loss of blood, anatomical abnormalities, pathological changing in chemical transformations and others is significant issue for many physiologists. In this connection should be pointed out that global processes are of special interest as they include feedbacks and interdependences among different regions of the organism. At the modern level of computer engineering the most adequate physical model for the dynamical description of cardiovascular system is the model of non-stationary flow of incompressible fluid through the system of elastic tubes. Mechanics of such flow is described by nonlinear set of hyperbolic equations including mass and momentum conservation joined with equation of state that determines elastic properties of the tube [
]. As we interested in global processes the models of the four vascular trees (arterial and venous parts of systemic and pulmonary circulation) must be closed with heart and peripheral circulation models. Heart operation is described by the model of fluid flow averaged by volume through the system of extensible chambers that results in the set of stiff ordinary differential equations [
]. When combined these models allow us to consider functional changes and responses as during one cardiac cycle and at a longer periods upon 10 minutes that
Pressure wave propagation through the large pulmonary arteries during one cardiac cycle. Grayscale designates divergence from the minimum pressure in each vessel.