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Polymer Bulletin
Erschienen in: Polymer Bulletin 7/2020

03.09.2019 | Original Paper

Improvement of antibacterial and biocompatibility properties of electrospray biopolymer films by ZnO and MCM-41

verfasst von: Esra Cansever Mutlu, Arzu Birinci Yıldırım, Muhammet Yıldırım, Anton Ficai, Denisa Ficai, Faik Nuzhet Oktar, Mihail Ţîţu, Ayhan Çetinkaya, Arzu Demir

Erschienen in: Polymer Bulletin | Ausgabe 7/2020

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Abstract

This study aims the improvement of antibacterial and biocompatibility properties of electrospray ternary blends of chitosan/poly(ethylene glycol)/hyaluronic acid. It conserves microscale particle structure even after incorporating zinc oxide (ZnO), the zeolite Mobil Composition of Matter No. 41 (MCM41) and penicillin G during this technique. Three different electrospray (ESP) blend compositions (ESPI, ESPII and ESPIII) have been produced in order to improve both antibacterial activity against to both gram-positive and gram-negative bacteria and biocompatibility. Results of FTIR spectroscopy and microscopy verified with SEM, EDS and AFM analyses. Hyaluronic acid surface has been specified definitely through ZnO-based ESPI surface composed of heterogeneously dispersed microparticles. Surface structures of ESPII and ESPIII have more homogenously dispersed microparticles as hill–valley surface by the aid of MCM 41-PEN. Antibacterial activity has been performed by Kirby–Bauer method. ESPI has good antibacterial activity against both gram-positive (S. aureus and S. epidermidis) and gram-negative bacteria (E. cloacea). Each electrospray film displayed good biocompatibility against to mouse fibroblast cell line L929 (ATTC number CCL-1). The highest amount of cell proliferation has been detected on ESPIII surface.
Vorheriger Artikel Dissolution of lignocellulosic biopolymers in ethanolamine-based protic ionic liquids
Nächster Artikel Evaluation of mechanical and thermal properties and creep behavior of micro- and nano-CaCO3 particle-filled HDPE nano- and microcomposites produced in large scale

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Metadaten
Titel
Improvement of antibacterial and biocompatibility properties of electrospray biopolymer films by ZnO and MCM-41
verfasst von
Esra Cansever Mutlu
Arzu Birinci Yıldırım
Muhammet Yıldırım
Anton Ficai
Denisa Ficai
Faik Nuzhet Oktar
Mihail Ţîţu
Ayhan Çetinkaya
Arzu Demir
Publikationsdatum
03.09.2019
Verlag
Springer Berlin Heidelberg
Erschienen in
Polymer Bulletin / Ausgabe 7/2020
Print ISSN: 0170-0839
Elektronische ISSN: 1436-2449
DOI
https://doi.org/10.1007/s00289-019-02937-2

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