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Erschienen in: Medical & Biological Engineering & Computing 10/2019

09.08.2019 | Original Article

Improving the power of objective response detection of evoked responses in noise by using average and product of magnitude-squared coherence of two different signals

verfasst von: Tiago Zanotelli, Antonio Mauricio Ferreira Leite Miranda de Sá, Eduardo Mazoni Andrade Marçal Mendes, Leonardo Bonato Felix

Erschienen in: Medical & Biological Engineering & Computing | Ausgabe 10/2019

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Abstract

Objective response detection (ORD) techniques such as the magnitude-squared coherence (MSC) are mathematical methods tailored to detect potentials evoked by an external periodic stimulation. The performance of the MSC is directly proportional to the signal-to-noise ratio (SNR) of the recorded signal and the time spent for collecting data. An alternative to increasing the performance of detection techniques without increasing data recording time is to use the information from more than one signal simultaneously. In this context, this work proposes two new detection techniques based on the average and on the product of MSCs of two different signals. The critical values and detection probabilities were obtained theoretically and using a Monte Carlo simulation. The performances of the new detectors were evaluated using synthetic data and electroencephalogram (EEG) signals during photo and auditory stimulation. For the synthetic signals, the two proposed detectors exhibited a higher detection rate when compared to the rate of the traditional MSC technique. When applied to EEG signals, these detectors resulted in an increase of the mean detection rate in relation to MSC for visual and auditory stimulation of at least 25% and 13.21%, respectively. The proposed detectors may be considered as promising tools for clinical applications.

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Glossar
κ A(f)
Average coherence
ASSR
Auditory steady-state response
CSM
Component synchrony measure
DR
Detection rate
EEG
Electroencephalogram
EP
Evoked potential
FP
False positives
H 0
Null hypothesis
MORD
Multivariate objective response detectors
MSC
Magnitude-squared coherence
NDR
Number of detected responses
NT
Number of tests
ORD
Objective response detection
PDF
Probability density function
PD
Probability of detecting
κ P(f)
Product coherence
SNR
Signal-to-noise
SFT
Spectral F-test (SFT)
Literatur
2.
Zurück zum Zitat Palaniappan R (2010) Biological signal analysis. Ventus Publishing, Denmark Palaniappan R (2010) Biological signal analysis. Ventus Publishing, Denmark
4.
10.
Zurück zum Zitat Kay SM (1998) Fundamentals of statistical signal processing, volume 2: detection theory. Signal Process II:672 Kay SM (1998) Fundamentals of statistical signal processing, volume 2: detection theory. Signal Process II:672
37.
Zurück zum Zitat Miranda de Sá AMFL, Felix LB (2002) Improving the detection of evoked responses to periodic stimulation by using multiple coherence – application during photic stimulation. Med Eng Phys 24:245–252CrossRef Miranda de Sá AMFL, Felix LB (2002) Improving the detection of evoked responses to periodic stimulation by using multiple coherence – application during photic stimulation. Med Eng Phys 24:245–252CrossRef
39.
Metadaten
Titel
Improving the power of objective response detection of evoked responses in noise by using average and product of magnitude-squared coherence of two different signals
verfasst von
Tiago Zanotelli
Antonio Mauricio Ferreira Leite Miranda de Sá
Eduardo Mazoni Andrade Marçal Mendes
Leonardo Bonato Felix
Publikationsdatum
09.08.2019
Verlag
Springer Berlin Heidelberg
Erschienen in
Medical & Biological Engineering & Computing / Ausgabe 10/2019
Print ISSN: 0140-0118
Elektronische ISSN: 1741-0444
DOI
https://doi.org/10.1007/s11517-019-02020-y

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