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01.06.2015 | Communication

In situ synthesis of conductive polypyrrole on electrospun cellulose nanofibers: scaffold for neural tissue engineering

verfasst von: Johannes Thunberg, Theodoros Kalogeropoulos, Volodymyr Kuzmenko, Daniel Hägg, Sara Johannesson, Gunnar Westman, Paul Gatenholm

Erschienen in: Cellulose | Ausgabe 3/2015

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This study reports the synthesis of conductive polypyrrole (PPy) on electrospun cellulose nanofibers. The cellulose nanofibers were electrospun via cellulose acetate and surface modified using in situ pyrrole polymerization. PPy adhered to the cellulose nanofiber surface as small particles and caused a 10⁵ fold increase in conductivity compared to unmodified cellulose nanofibers. In addition, tests revealed no cytotoxic potential for the PPy coated cellulose nanofiber materials. In vitro culturing using SH-SY5Y human neuroblastoma cells indicated enhanced cell adhesion on the PPy coated cellulose material. SH-SY5Y cell viability was evident up to 15 days of differentiation and cells adhered to the PPy coated cellulose nanofibers and altered their morphology to a more neuron like phenotype.

Vorheriger Artikel Surface-restricted modification of nanocellulose aerogels in gas-phase esterification by di-functional fatty acid reagents

Nächster Artikel Vibrational spectral signatures of crystalline cellulose using high resolution broadband sum frequency generation vibrational spectroscopy (HR-BB-SFG-VS)

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Titel: In situ synthesis of conductive polypyrrole on electrospun cellulose nanofibers: scaffold for neural tissue engineering
verfasst von: Johannes Thunberg
Theodoros Kalogeropoulos
Volodymyr Kuzmenko
Daniel Hägg
Sara Johannesson
Gunnar Westman
Paul Gatenholm
Publikationsdatum: 01.06.2015
Verlag: Springer Netherlands
Erschienen in: Cellulose / Ausgabe 3/2015
Print ISSN: 0969-0239
Elektronische ISSN: 1572-882X
DOI: https://doi.org/10.1007/s10570-015-0591-5

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