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Journal of Materials Science
Erschienen in: Journal of Materials Science 1/2015

01.01.2015 | Original Paper

In vitro cytocompatibility and corrosion resistance of zinc-doped hydroxyapatite coatings on a titanium substrate

verfasst von: Qiongqiong Ding, Xuejiao Zhang, Yong Huang, Yajing Yan, Xiaofeng Pang

Erschienen in: Journal of Materials Science | Ausgabe 1/2015

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Abstract

To improve biocompatibility and corrosion resistance during the initial implantation stage, zinc-substituted hydroxyapatite (ZnHAp) coating was fabricated on pure titanium by the electrolytic deposition method. The morphology, microstructure and chemical composition of the coating were investigated by X-ray diffraction, scanning electron microscopy, energy-dispersive X-ray analysis and Fourier transform infrared spectroscopy. The prepared ZnHAp crystals were calcium deficient and were carbonated owing to the incorporation of some Zn2+. This incorporation of Zn2+ into the HAp significantly reduced porosity and caused the coating to become noticeably denser. In addition, the Zn2+ ions were homogeneously distributed in the coating. The potentiodynamic polarisation test revealed that the ZnHAp-coated surface showed superior corrosion resistance over that of the HAp-coated surface and bare Ti. The in vitro bioactivity was evaluated in a simulated body fluid, which revealed that the ZnHAp coating can rapidly induce bone-like apatite formation of nuclear and growth features. In addition, the cell response tests showed that the MC3T3-E1 cells on the ZnHAp coating clearly enhanced the in vitro cytocompatibility of Ti compared with the same cells on HAp coating. ZnHAp coating was thus beneficial for improving biocompatibility.
Vorheriger Artikel Kinetics of triple-junctions in eutectic solidification: a sharp interface model
Nächster Artikel Subsolidus phase relations of Li2O–FeO–P2O5 system and the solid solubility of Li1+x Fe1−x PO4 compounds under Ar/H2 atmosphere

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Metadaten
Titel
In vitro cytocompatibility and corrosion resistance of zinc-doped hydroxyapatite coatings on a titanium substrate
verfasst von
Qiongqiong Ding
Xuejiao Zhang
Yong Huang
Yajing Yan
Xiaofeng Pang
Publikationsdatum
01.01.2015
Verlag
Springer US
Erschienen in
Journal of Materials Science / Ausgabe 1/2015
Print ISSN: 0022-2461
Elektronische ISSN: 1573-4803
DOI
https://doi.org/10.1007/s10853-014-8578-4

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