Internet of Things (IoT) is a network of physical things, which includes variety of smart sensing devices connected over the internet. These devices continuously monitor their surrounding parameters such as temperature, humidity, pressure, healthcare information, etc.; moreover, communication takes place among the devices thereby substantiating an intelligent IoT system. The benefit of this system is to convert raw data into meaningful information. It helps in taking involuntary decisions for the specific purpose for which the system is designed. Abundant ingenious applications have been developed in the past using IoT, which are completely solitary. These applications provide efficiency and flexibility to the manual work, which were initially carried out without an application of IoT. Research community is continuously striving for automation, and thereby better solution is being provided by IoT. Moreover, an availability of varieties of IoT devices makes the IoT systems more intelligent and smarter day-by-day. It is predicted that, in the near future, everything around us will use an internet for communication and will become an Internet of Everything (IoE). The future will be de facto steered by IoE where people, data, process, and things will be tied together to provide more relevant and valuable information than ever before. It is an upcoming distributed technology, providing great experience and groundbreaking opportunities in the business. This chapter presents diverse applications of IoT by adopting IoE in different domains such as agriculture, security, medical, industry, domestic, wearable, etc. with the emphasis on issues, challenges, and applicability.