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2017 | OriginalPaper | Buchkapitel

Intramolecular Arylation of 2-Nitrobenzenesulfonamides: A Route to Diverse Nitrogenous Heterocycles

verfasst von : Eva Schütznerová, Viktor Krchňák

Erschienen in: Solid-Phase Synthesis of Nitrogenous Heterocycles

Verlag: Springer International Publishing

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Abstract

In addition to being an integral component of numerous drugs, 2- and 4-nitrobenzenesulfonyl (Nos) groups are used as protecting/activating agents for the selective alkylation of primary amines. 2-Nos amides are also useful intermediates for the synthesis of fused nitrogenous heterocycles. This chapter focuses on the use of 2-Nos amides as intramolecular arylation agents and on the application of C- and N-aryl derivatives for the synthesis of diverse heterocycles in the solid phase.

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Titel: Intramolecular Arylation of 2-Nitrobenzenesulfonamides: A Route to Diverse Nitrogenous Heterocycles
verfasst von: Eva Schütznerová
Viktor Krchňák
Verlag: Springer International Publishing
Buch: Solid-Phase Synthesis of Nitrogenous Heterocycles
Print ISBN: 978-3-319-58615-1

Electronic ISBN: 978-3-319-58616-8

Copyright-Jahr: 2017
DOI: https://doi.org/10.1007/7081_2016_5