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Erschienen in: International Journal of Computer Assisted Radiology and Surgery 5/2014

01.09.2014 | Original Article

Intraoperative segmentation of iodine and palladium radioactive sources in C-arm images

verfasst von: Chiara Amat di San Filippo, Gabor Fichtinger, William James Morris, Septimiu E. Salcudean, Ehsan Dehghan, Pascal Fallavollita

Erschienen in: International Journal of Computer Assisted Radiology and Surgery | Ausgabe 5/2014

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Abstract

Purpose

   Dynamic dosimetry is becoming the standard to evaluate the quality of radioactive implants during brachytherapy. For this, it is essential to obtain a 3D visualization of the implanted seeds and their relative position to the prostate. A method was developed to obtain a robust and precise segmentation of seeds in C-arm images, and this approach was tested using clinical datasets.

Method

   A region-based implicit active contour approach was used to delineate implanted seeds. Then, a template-based matching was employed to segment iodine implants whereas a K-means algorithm is implemented to resolve palladium seed clusters. To validate the method, 55 C-arm images from 10 patients were used for the segmentation of iodine sources, whereas 225 C-arm images from 16 patients were used for the palladium case.

Results

   Compared to manual ground truth segmentation of 6,002 iodine seeds and 15,354 palladium seeds, 98.7 % of iodine sources were automatically detected and declustered showing a false-positive rate of only 1.7 %. A total of 98.7 % of palladium sources were automatically detected and declustered with a false-positive rate of only 2.0 %.

Conclusion

   An automated segmentation method was developed that is able to perform the identification and annotation processes of seeds on par with a human expert. This method was shown to be robust and suitable for integration in the dynamic dosimetry workflow of prostate brachytherapy interventions.

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Literatur
1.
Zurück zum Zitat Siegel R, Naishadham D, Jemal A (2013) Cancer statistics. CA Cancer J Clin 63(1):11–30 Siegel R, Naishadham D, Jemal A (2013) Cancer statistics. CA Cancer J Clin 63(1):11–30
2.
Zurück zum Zitat Nag S, Ciezki JP, Cormack R, Doggett S, DeWyngaert K, Edmundson GK, Stock RG, Stone NN, Yu Y, Zelefsky M (2001) Intraoperative planning and evaluation of permanent prostate brachytherapy: report of the American brachytherapy society. Int J Radiat Oncol Biol Phys 51(5):1422PubMedCrossRef Nag S, Ciezki JP, Cormack R, Doggett S, DeWyngaert K, Edmundson GK, Stock RG, Stone NN, Yu Y, Zelefsky M (2001) Intraoperative planning and evaluation of permanent prostate brachytherapy: report of the American brachytherapy society. Int J Radiat Oncol Biol Phys 51(5):1422PubMedCrossRef
3.
Zurück zum Zitat Lee J, Labat C, Jain AK, Song DY, Burdette CE, Fichtinger G, Prince JL (2011) REDMAPS: reduced-dimensionality matching for prostate brachytherapy seed reconstruction. IEEE Trans Med Imaging 30(1):38–51PubMedCrossRefPubMedCentral Lee J, Labat C, Jain AK, Song DY, Burdette CE, Fichtinger G, Prince JL (2011) REDMAPS: reduced-dimensionality matching for prostate brachytherapy seed reconstruction. IEEE Trans Med Imaging 30(1):38–51PubMedCrossRefPubMedCentral
4.
Zurück zum Zitat Dehghan E, Lee J, Fallavollita P, Kuo N, Deguet A, Le Y, Burdette CE, Song DY, Prince JL, Fichtinger G (2012) Ultrasound-fluoroscopy registration for prostate brachytherapy dosimetry. Med Image Anal 16(7):1347–1358PubMedCrossRefPubMedCentral Dehghan E, Lee J, Fallavollita P, Kuo N, Deguet A, Le Y, Burdette CE, Song DY, Prince JL, Fichtinger G (2012) Ultrasound-fluoroscopy registration for prostate brachytherapy dosimetry. Med Image Anal 16(7):1347–1358PubMedCrossRefPubMedCentral
5.
Zurück zum Zitat Lam S, Marks RJ, Cho PS (2001) Prostate brachytherapy seed segmentation using spoke transform. SPIE 4322(1):1490–1500 Lam S, Marks RJ, Cho PS (2001) Prostate brachytherapy seed segmentation using spoke transform. SPIE 4322(1):1490–1500
6.
Zurück zum Zitat Tubic D, Zaccarin A, Beaulieu L, Pouliot J (2001) Automated seed detection and three-dimensional reconstruction. i. Seed localization from fluoroscopic images or radiographs. Med Phys 28(11):2272–2279 Tubic D, Zaccarin A, Beaulieu L, Pouliot J (2001) Automated seed detection and three-dimensional reconstruction. i. Seed localization from fluoroscopic images or radiographs. Med Phys 28(11):2272–2279
7.
Zurück zum Zitat Kuo N, Deguet N, Song A, Burdette DY, Prince EC, Lee JL (2012) Automatic segmentation of radiographic fiducial and seeds from X-ray images in prostate brachytherapy. Med Eng Phys 34(1):64–77 Kuo N, Deguet N, Song A, Burdette DY, Prince EC, Lee JL (2012) Automatic segmentation of radiographic fiducial and seeds from X-ray images in prostate brachytherapy. Med Eng Phys 34(1):64–77
8.
Zurück zum Zitat Moult E, Fichtinger G, Morris WJ, Salcudean SE, Dehghan E, Fallavollita P (2012) Segmentation of iodine brachytherapy implants in fluoroscopy. IJCARS 7(6):871–879 Moult E, Fichtinger G, Morris WJ, Salcudean SE, Dehghan E, Fallavollita P (2012) Segmentation of iodine brachytherapy implants in fluoroscopy. IJCARS 7(6):871–879
9.
Zurück zum Zitat Amat di San Filippo C, Fichtinger G, Morris WJ, Salcudean SE, Dehghan E, Fallavollita P (2013) Declustering n-connected components for segmentation of iodine implants in C-arm fluoroscopy images. IPCAI 7915:101–110 Amat di San Filippo C, Fichtinger G, Morris WJ, Salcudean SE, Dehghan E, Fallavollita P (2013) Declustering n-connected components for segmentation of iodine implants in C-arm fluoroscopy images. IPCAI 7915:101–110
10.
Zurück zum Zitat Hu Y-c, Xiong J-p, Cohan G, Zaider M, Mageras G, Zelefsky M (2013) Fast radioactive seed localization in intraoperative cone beam CT for low-dose-rate prostate brachytherapy. Proc SPIE 8671, id. 867108 7 pp Hu Y-c, Xiong J-p, Cohan G, Zaider M, Mageras G, Zelefsky M (2013) Fast radioactive seed localization in intraoperative cone beam CT for low-dose-rate prostate brachytherapy. Proc SPIE 8671, id. 867108 7 pp
11.
Zurück zum Zitat Hoskin P, Coyle C (2011) Radiotherapy in practice—brachytherapy. Radiotherapy in practice series. Oxford University Press, OxfordCrossRef Hoskin P, Coyle C (2011) Radiotherapy in practice—brachytherapy. Radiotherapy in practice series. Oxford University Press, OxfordCrossRef
12.
Zurück zum Zitat Li C, Kao C, Gore JC, Ding Z (2008) Minimization of region-scalable fit- ting energy for image segmentation. IEEE Trans Image Process 17:1940–1949PubMedCrossRefPubMedCentral Li C, Kao C, Gore JC, Ding Z (2008) Minimization of region-scalable fit- ting energy for image segmentation. IEEE Trans Image Process 17:1940–1949PubMedCrossRefPubMedCentral
13.
Zurück zum Zitat Kirsch RA (1971) Computer determination of the constituent structure of biological images. Comput Biomed Res 4:315–328PubMedCrossRef Kirsch RA (1971) Computer determination of the constituent structure of biological images. Comput Biomed Res 4:315–328PubMedCrossRef
14.
Zurück zum Zitat Su Y, Davis B, Herman M, Manduca A, Robb R (2001) Examination of dosimetry accuracy as a function of seed detection rate in permanent prostate brachytherapy. Med Phys 32:30493056 Su Y, Davis B, Herman M, Manduca A, Robb R (2001) Examination of dosimetry accuracy as a function of seed detection rate in permanent prostate brachytherapy. Med Phys 32:30493056
15.
Zurück zum Zitat Kuo N, Dehghan E, Deguet A, Song DY, Prince JL, Lee J (Feb 9–14, 2013) An intraoperative dynamic dosimetry guidance system for prostate brachytherapy. In: SPIE medical imaging, Lake Buena Vista, FL Kuo N, Dehghan E, Deguet A, Song DY, Prince JL, Lee J (Feb 9–14, 2013) An intraoperative dynamic dosimetry guidance system for prostate brachytherapy. In: SPIE medical imaging, Lake Buena Vista, FL
Metadaten
Titel
Intraoperative segmentation of iodine and palladium radioactive sources in C-arm images
verfasst von
Chiara Amat di San Filippo
Gabor Fichtinger
William James Morris
Septimiu E. Salcudean
Ehsan Dehghan
Pascal Fallavollita
Publikationsdatum
01.09.2014
Verlag
Springer Berlin Heidelberg
Erschienen in
International Journal of Computer Assisted Radiology and Surgery / Ausgabe 5/2014
Print ISSN: 1861-6410
Elektronische ISSN: 1861-6429
DOI
https://doi.org/10.1007/s11548-014-0983-2

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