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Erschienen in:
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2020 | OriginalPaper | Buchkapitel

1. Introduction

verfasst von : Andreas Grimmer, Robert Wille

Erschienen in: Designing Droplet Microfluidic Networks

Verlag: Springer International Publishing

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Abstract

This chapter provides an introduction into microfluidics in general and droplet microfluidic networks in particular. It briefly reviews the state-of-the-art design process for such devices and discusses the contributions made in this book to improve it. By this, the chapter gives an overview of the book and its contributions.

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Nächstes Kapitel Background
Fußnoten
1
 
3
A bypass channel [20] connects the endpoints of the two successor channels. This bypass cannot be entered by any droplet and is used to make the droplet routing only dependent on the resistances of the successors.
 
4
Note that simulation as proposed in Chap. 3 often also provides the basis for other contributions (cf. Chap. 4 or 8) and, hence, is covered right after the Background in Chap. 3.
 
Literatur
6.
A. Biral, A. Zanella, Introducing purely hydrodynamic networking functionalities into microfluidic systems. Nano Commun. Netw. 4(4), 205–215 (2013)CrossRef
13.
X. Chen, C.L. Ren, A microfluidic chip integrated with droplet generation, pairing, trapping, merging, mixing and releasing. RSC Adv. 7(27), 16738–16750 (2017)CrossRef
20.
G. Cristobal, J.-P. Benoit, M. Joanicot, A. Ajdari, Microfluidic bypass for efficient passive regulation of droplet traffic at a junction. Appl. Phys. Lett. 89(3), 34104–34104 (2006)CrossRef
32.
M.J. Fuerstman, A. Lai, M.E. Thurlow, S.S. Shevkoplyas, H.A. Stone, G.M. Whitesides, The pressure drop along rectangular microchannels containing bubbles. Lab Chip 7(11), 1479–1489 (2007)CrossRef
35.
T. Glatzel, C. Litterst, C. Cupelli, T. Lindemann, C. Moosmann, R. Niekrawietz, W. Streule, R. Zengerle, P. Koltay, Computational fluid dynamics (CFD) software tools for microfluidic applications–a case study. Comput. Fluids 37(3), 218–235 (2008)MATHCrossRef
36.
T. Glawdel, C.L. Ren, Global network design for robust operation of microfluidic droplet generators with pressure-driven flow. Microfluid. Nanofluid. 13(3), 469–480 (2012)CrossRef
37.
T. Glawdel, C. Elbuken, C. Ren, Passive droplet trafficking at microfluidic junctions under geometric and flow asymmetries. Lab Chip 11(22), 3774–3784 (2011)CrossRef
43.
A. Grimmer, W. Haselmayr, A. Springer, R. Wille, A discrete model for Networked Labs-on-Chips: linking the physical world to design automation, in Design Automation Conference (2017), pp. 50:1–50:6
44.
A. Grimmer, W. Haselmayr, A. Springer, R. Wille, Verification of Networked Labs-on-Chip architectures, in Design, Automation and Test in Europe (2017), pp. 1679–1684
45.
A. Grimmer, Q. Wang, H. Yao, T.-Y. Ho, R. Wille, Close-to-optimal placement and routing for continuous-flow microfluidic biochips, in Asia and South Pacific Design Automation Conference (2017), pp. 530–535
46.
A. Grimmer, X. Chen, M. Hamidović, W. Haselmayr, C.L. Ren, R. Wille, Simulation before fabrication: a case study on the utilization of simulators for the design of droplet microfluidic networks. RSC Adv. 8, 34733–34742 (2018)CrossRef
47.
A. Grimmer, P. Frank, P. Ebner, S. Häfner, A. Richter, R. Wille, Meander designer: automatically generating meander channel designs. Micromach. J. Micro/Nano Sci. Dev. Appl. 9(12), 625 (2018)CrossRef
48.
A. Grimmer, W. Haselmayr, A. Springer, R. Wille, Design of application-specific architectures for Networked Labs-on-Chips. Trans. Comput. Aided Des. Integr. Circuits Syst. 37(1), 193–202 (2018)CrossRef
49.
50.
52.
53.
D.T. Grissom, P. Brisk, Fast online synthesis of digital microfluidic biochips. Trans. Comput. Aided Des. Integr. Circuits Syst. 33(3), 356–369 (2014)CrossRef
54.
D. Grissom, K. O’Neal, B. Preciado, H. Patel, R. Doherty, N. Liao, P. Brisk, A digital microfluidic biochip synthesis framework, in International Conference on Very Large Scale Integration of System-on-Chip (2012), pp. 177–182
55.
H. Gu, M.H. Duits, F. Mugele, Droplets formation and merging in two-phase flow microfluidics. Int. J. Mol. Sci. 12(4), 2572–2597 (2011)CrossRef
56.
S. Haeberle, R. Zengerle, Microfluidic platforms for Lab-on-a-Chip applications. Lab Chip 7, 1094–1110 (2007)CrossRef
62.
Y.-L. Hsieh, T.-Y. Ho, K. Chakrabarty, Biochip synthesis and dynamic error recovery for sample preparation using digital microfluidics. Trans. Comput. Aided Des. Integr. Circuits Syst. 33(2), 183–196 (2014)CrossRef
63.
K. Hu, F. Yu, T.-Y. Ho, K. Chakrabarty, Testing of flow-based microfluidic biochips: fault modeling, test generation, and experimental demonstration. Trans. Comput. Aided Des. Integr. Circuits Syst. 33(10), 1463–1475 (2014)CrossRef
64.
W.-L. Huang, A. Gupta, S. Roy, T.-Y. Ho, P. Pop, Fast architecture-level synthesis of fault-tolerant flow-based microfluidic biochips, in Design, Automation and Test in Europe (2017), pp. 1671–1676
71.
O. Keszocze, R. Wille, T.-Y. Ho, R. Drechsler, Exact one-pass synthesis of digital microfluidic biochips, in Design Automation Conference (2014), pp. 1–6
73.
O. Keszocze, Z. Li, A. Grimmer, R. Wille, K. Chakrabarty, R. Drechsler, Exact routing for micro-electrode-dot-array digital microfluidic biochips, in Asia and South Pacific Design Automation Conference (2017)
82.
E. Maftei, P. Pop, J. Madsen, Tabu search-based synthesis of digital microfluidic biochips with dynamically reconfigurable non-rectangular devices. J. Des. Autom. Embed. Syst. 14(3), 287–307 (2010)CrossRef
86.
J. McDaniel, B. Crites, P. Brisk, W.H. Grover, Flow-layer physical design for microchips based on monolithic membrane valves. J. Des. Test 32(6), 51–59 (2015)
87.
W.H. Minhass, P. Pop, J. Madsen, System-level modeling and synthesis of flow-based microfluidic biochips, in International Conference on Compilers, Architecture and Synthesis for Embedded Systems (2011), pp. 225–233
88.
W.H. Minhass, P. Pop, J. Madsen, F.S. Blaga, Architectural synthesis of flow-based microfluidic large-scale integration biochips, in International Conference on Compilers, Architecture and Synthesis for Embedded Systems (2012), pp. 181–190
89.
D. Mitra, S. Roy, S. Bhattacharjee, K. Chakrabarty, B.B. Bhattacharya, On-chip sample preparation for multiple targets using digital microfluidics. Trans. Comput. Aided Des. Integr. Circuits Syst. 33(8), 1131–1144 (2014)CrossRef
91.
G.E. Moore, Cramming more components onto integrated circuits. Electronics 38(8), 114–117 (1965)
93.
K.W. Oh, K. Lee, B. Ahn, E.P. Furlani, Design of pressure-driven microfluidic networks using electric circuit analogy. Lab Chip 12(3), 515–545 (2012)CrossRef
95.
S. Poddar, S. Ghoshal, K. Chakrabarty, B.B. Bhattacharya, Error-correcting sample preparation with cyberphysical digital microfluidic Lab-on-Chip. Trans. Des. Autom. Electron. Syst. 22(1), 2 (2016)CrossRef
96.
M.G. Pollack, A.D. Shenderov, R.B. Fair, Electrowetting-based actuation of droplets for integrated microfluidics. Lab Chip 2(2), 96–101 (2002)CrossRef
97.
P. Pop, I.E. Araci, K. Chakrabarty, Continuous-flow biochips: technology, physical-design methods, and testing. J. Des. Test 32(6), 8–19 (2015)
99.
S. Roy, B.B. Bhattacharya, S. Ghoshal, K. Chakrabarty, High-throughput dilution engine for sample preparation on digital microfluidic biochips. IET Comput. Digit. Tech. 8(4), 163–171 (2014)CrossRef
101.
M. Schindler, A. Ajdari, Droplet traffic in microfluidic networks: a simple model for understanding and designing. Phys. Rev. Lett. 100(4), 044501 (2008)
103.
M.F. Schmidt, W.H. Minhass, P. Pop, J. Madsen, Modeling and simulation framework for flow-based microfluidic biochips, in Symposium on Design, Test, Integration & Packaging of MEMS/MOEMS (2013), pp. 1–6
111.
F. Su, K. Chakrabarty, High-level synthesis of digital microfluidic biochips. J. Emerg. Technol. Comput. Syst. 3(4), 1 (2008)CrossRef
112.
F. Su, S. Ozev, K. Chakrabarty, Testing of droplet-based microelectrofluidic systems, in International Test Conference, vol. 46 (2003), pp. 1192–1200
113.
F. Su, W. Hwang, K. Chakrabarty, Droplet routing in the synthesis of digital microfluidic biochips, in Design, Automation and Test in Europe, vol. 1 (2006), pp. 1–6
117.
S.-Y. Teh, R. Lin, L.-H. Hung, A.P. Lee, Droplet microfluidics. Lab Chip 8, 198–220 (2008)CrossRef
121.
K.-H. Tseng, S.-C. You, J.-Y. Liou, T.-Y. Ho, A top-down synthesis methodology for flow-based microfluidic biochips considering valve-switching minimization, in International Symposium on Physical Design (2013), pp. 123–129
122.
S.A. Vanapalli, A.G. Banpurkar, D. van den Ende, M.H. Duits, F. Mugele, Hydrodynamic resistance of single confined moving drops in rectangular microchannels. Lab Chip 9(7), 982–990 (2009)CrossRef
126.
G.M. Whitesides, The origins and the future of microfluidics. Nature 442(7101), 368–373 (2006)CrossRef
127.
R. Wille, O. Keszocze, R. Drechsler, T. Boehnisch, A. Kroker, Scalable one-pass synthesis for digital microfluidic biochips. J. Des. Test 32(6), 41–50 (2015)
128.
M. Wörner, Numerical modeling of multiphase flows in microfluidics and micro process engineering: a review of methods and applications. Microfluid. Nanofluid. 12(6), 841–886 (2012)CrossRef
129.
T. Xu, K. Chakrabarty, Integrated droplet routing in the synthesis of microfluidic biochips, in Design Automation Conference (2007), pp. 948–953
131.
Y. Zhao, K. Chakrabarty, Design and Testing of Digital Microfluidic Biochips (Springer, New York, 2012)
Metadaten
Titel
Introduction
verfasst von
Andreas Grimmer
Robert Wille
Copyright-Jahr
2020
Buch
Designing Droplet Microfluidic Networks

Print ISBN: 978-3-030-20712-0

Electronic ISBN: 978-3-030-20713-7

Copyright-Jahr: 2020

DOI
https://doi.org/10.1007/978-3-030-20713-7_1

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