Abstract
Mesoporous glass beads and 5 μm silica particles were modified with beta-cyclodextrin ( Β-CD) by means of directly bonding, linking spacer group, and cross-linking agent. The selectivities of the Β-CD modified silica particles were measured by simple column chromatography to separate a model mixture of 1-and 2-hydroxy-naphthalene (naphthols) and ortho, meta, and para-xylene. In the packed column chromatography experiments, two major controlling factors (inclusion complex formation effect and steric hindrance effect of the analytes) on the separations were observed. The elusion orders of the Β-CD directly bonded glass beads were meta-, para-, ortho-xylene and 1-naphthol, 2-naphthol. The phenomena of Β-CD pore blocking and narrowing by spacer groups and cross-linking agent were observed. The spacer group and cross-linking agent decreased inclusion complex formation of 2-naphthol.
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This paper is dedicated to Professor Hyun-Ku Rhee on the occasion of his retirement from Seoul National University.
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Kim, M., Way, J.D. & Baldwin, R.M. Effects of cross-linking and spacer groups on beta-cyclodextrin bonded liquid chromatographic separation. Korean J. Chem. Eng. 21, 465–468 (2004). https://doi.org/10.1007/BF02705436
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DOI: https://doi.org/10.1007/BF02705436